Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" AARS2 "AARSL, bA444E17.1, KIAA1270" ENSG00000124608 "Alanyl-tRNA synthetase 2, mitochondrial" Q5JTZ9 6 44298731-44313347 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration, Premature ovarian failure, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035636, HPA061396" Approved Enhanced Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 64: Non-specific - Transcription" Mitochondria "HPA035636: AB_10670837, HPA061396: AB_2684502" "unprognostic (1.56e-1)" "unprognostic (3.24e-2)" "unprognostic (2.58e-2)" "unprognostic (2.04e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.83e-3)" "unprognostic (5.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-2)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" ACAD9 "MGC14452, NPD002" ENSG00000177646 "Acyl-CoA dehydrogenase family member 9" Q9H845 3 128879596-128924003 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037716, HPA046720" Supported Enhanced Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 43: Non-specific - Mitochondria" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA037716: AB_10673638, HPA046720: AB_2679773" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.61e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.67e-6)" "unprognostic (1.30e-1)" "unprognostic (3.74e-1)" "unprognostic (3.25e-2)" "unprognostic (1.37e-1)" "unprognostic (6.96e-3)" "prognostic favorable (4.32e-8)" "unprognostic (1.52e-1)" "unprognostic (2.64e-2)" "unprognostic (6.56e-2)" "unprognostic (9.96e-2)" AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein binding" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favorable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" AGK "FLJ10842, MULK" ENSG00000006530 "Acylglycerol kinase" Q53H12 7 141551278-141655244 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Cardiomyopathy, Cataract, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 97.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020959, HPA053471" Supported Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 7: NK-cells - Immune response regulation" Mitochondria Vesicles "HPA020959: AB_1854206, HPA053471: AB_2682164" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.28e-2)" "unprognostic (9.47e-3)" "unprognostic (5.43e-2)" "unprognostic (2.15e-2)" "unprognostic (3.68e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (6.24e-3)" "unprognostic (7.90e-2)" "unprognostic (9.29e-2)" "unprognostic (9.65e-2)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Intellectual disability, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 232.2;Proximal tubular cells: 331.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 48: Non-specific - RNA binding" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" ATAD3A FLJ10709 ENSG00000197785 "ATPase family AAA domain containing 3A" Q9NVI7 1 1512162-1534685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058968, HPA064867, HPA065305" Approved Enhanced Mitochondria NA NA 27000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 38: Non-specific - mRNA processing" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA058968: AB_2683864, HPA064867: AB_2685375, HPA065305: AB_2685459" "unprognostic (8.42e-2)" "unprognostic (1.67e-1)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.50e-1)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.90e-5)" "unprognostic (6.62e-2)" "unprognostic (9.53e-2)" "unprognostic (5.81e-2)" "unprognostic (4.09e-2)" "unprognostic (7.66e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (3.09e-1)" "unprognostic (6.25e-2)" "unprognostic (1.87e-3)" ATP5F1A "ATP5A, ATP5A1, ATP5AL2, ATPM, hATP1, OMR, ORM" ENSG00000152234 "ATP synthase F1 subunit alpha" P25705 18 46080248-46104334 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1760.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2292.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013067, HPA040622, HPA044202" Enhanced Supported Mitochondria NA NA 8800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: Non-specific - Cilium assembly" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "CAB013067: AB_221511, HPA040622: AB_2677048, HPA044202: AB_2678855" "unprognostic (3.08e-2)" "unprognostic (9.13e-2)" "unprognostic (1.84e-2)" "unprognostic (3.54e-1)" "unprognostic (6.36e-2)" "unprognostic (2.61e-1)" "unprognostic (1.89e-2)" "unprognostic (6.79e-2)" "unprognostic (8.31e-2)" "unprognostic (4.79e-2)" "unprognostic (7.30e-3)" "unprognostic (1.50e-2)" "prognostic favorable (1.22e-15)" "unprognostic (4.60e-3)" "unprognostic (2.06e-1)" "unprognostic (1.77e-1)" "unprognostic (4.87e-3)" ATP5F1D ATP5D ENSG00000099624 "ATP synthase F1 subunit delta" P30049 19 1241746-1244825 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 806.2" "Cell type enhanced" "Detected in all" "Distal enterocytes: 2045.1;Proximal enterocytes: 1988.9;Proximal tubular cells: 1817.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002865 Approved NA NA 160000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 53: Non-specific - mRNA processing" "Cluster 50: Enterocytes - Absorption" "HPA002865: AB_1078244" "unprognostic (4.80e-2)" "unprognostic (9.34e-2)" "unprognostic (7.77e-2)" "prognostic favorable (1.23e-4)" "unprognostic (1.64e-2)" "unprognostic (1.95e-1)" "unprognostic (4.63e-2)" "unprognostic (6.75e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-1)" "prognostic favorable (4.60e-4)" "unprognostic (6.95e-2)" "prognostic favorable (3.46e-5)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "unprognostic (3.74e-1)" "unprognostic (3.49e-2)" ATP5F1E ATP5E ENSG00000124172 "ATP synthase F1 subunit epsilon" P56381 20 59025475-59032345 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 4576.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (1.73e-1)" "unprognostic (6.30e-2)" "unprognostic (8.16e-2)" "unprognostic (9.04e-2)" "unprognostic (2.16e-1)" "unprognostic (1.92e-3)" "unprognostic (7.88e-3)" "unprognostic (2.51e-1)" "unprognostic (5.01e-2)" "unprognostic (6.41e-2)" "unprognostic (4.35e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (3.98e-1)" "unprognostic (3.21e-1)" "unprognostic (1.67e-1)" "unprognostic (2.44e-2)" ATP5MD "bA792D24.4, DAPIT, MGC14697, USMG5" ENSG00000173915 "ATP synthase membrane subunit DAPIT" Q96IX5 10 103389041-103396492 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4842.3;Hepatocytes: 2211.0;Proximal tubular cells: 2198.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044798 Supported Mitochondria NA NA 55000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA044798: AB_2679091" "unprognostic (4.41e-2)" "unprognostic (3.08e-2)" "unprognostic (2.59e-1)" "unprognostic (7.93e-2)" "unprognostic (1.65e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (5.67e-2)" "unprognostic (1.57e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (7.46e-2)" "unprognostic (1.03e-2)" ATPAF2 "ATP12, Atp12p, LP3663, MGC29736" ENSG00000171953 "ATP synthase mitochondrial F1 complex assembly factor 2" Q8N5M1 17 17977409-18039209 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "testis cancer: 104.2" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023329, HPA059422" Supported Enhanced Cytosol No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 49: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Cytosol "HPA023329: AB_1845209, HPA059422: AB_2684011" "unprognostic (3.16e-2)" "unprognostic (1.98e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.95e-4)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (2.70e-3)" "unprognostic (1.67e-2)" "prognostic favorable (6.00e-5)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (5.15e-1)" "unprognostic (2.62e-2)" BCS1L "BCS, BJS, h-BCS, Hs.6719" ENSG00000074582 "BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone" Q9Y276 2 218658764-218663443 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037700, HPA037701" Supported NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 35: Non-specific - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" "HPA037700: AB_10794619, HPA037701: AB_10805235" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (6.28e-2)" "unprognostic (4.99e-2)" "unprognostic (6.44e-2)" "unprognostic (4.31e-1)" "unprognostic (4.25e-2)" "unprognostic (2.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.83e-2)" "unprognostic (1.21e-2)" "unprognostic (6.02e-2)" "unprognostic (3.47e-3)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" "unprognostic (8.38e-2)" "prognostic favorable (3.31e-4)" BOLA3 ENSG00000163170 "BolA family member 3" Q53S33 2 74135400-74147912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 173.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 488.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046393, HPA053162" Uncertain Supported "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Enzymes" "Cluster 16: Non-specific - RNA binding" "Nuclear bodies, Mitochondria" Cytosol "HPA046393: , HPA053162: AB_2682063" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.83e-2)" "unprognostic (4.23e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.86e-3)" "unprognostic (8.03e-2)" "unprognostic (1.60e-2)" "unprognostic (4.03e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (9.90e-5)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (4.40e-1)" C12orf65 "FLJ38663, SPG55" ENSG00000130921 "Chromosome 12 open reading frame 65" Q9H3J6 12 123233385-123258079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.0" "Cell type enhanced" "Detected in all" "Spermatocytes: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057595 Approved Approved Nucleoplasm,Mitochondria,Cytosol No Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 63: T-cells - Adaptive immune response" "Cluster 45: Non-specific - Cell proliferation" "Cluster 11: Non-specific - Transcription" "Nucleoplasm, Cytosol" Mitochondria "HPA057595: " "unprognostic (9.07e-3)" "unprognostic (1.51e-2)" "unprognostic (5.30e-2)" "unprognostic (8.19e-3)" "unprognostic (1.23e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (4.29e-9)" "unprognostic (9.33e-3)" "unprognostic (2.39e-1)" "unprognostic (2.50e-2)" "unprognostic (6.33e-3)" "unprognostic (1.20e-2)" "unprognostic (2.01e-2)" "unprognostic (3.89e-2)" "unprognostic (3.19e-2)" "unprognostic (9.83e-3)" "prognostic favorable (7.82e-5)" C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA 410000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 49: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" "Plasma membrane" Mitochondria "HPA026483: AB_1847108" "unprognostic (2.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (6.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (4.62e-2)" "unprognostic (2.40e-3)" "unprognostic (6.03e-2)" "unprognostic (4.60e-3)" "unprognostic (3.08e-2)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (3.97e-1)" CARS2 FLJ12118 ENSG00000134905 "Cysteinyl-tRNA synthetase 2, mitochondrial" Q9HA77 13 110641412-110713603 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 220.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041776 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 13: Non-specific - Nuclear processes" "Cluster 19: Macrophages - Innate immune response" "Nucleoplasm, Mitochondria" "HPA041776: AB_2677666" "unprognostic (2.34e-3)" "unprognostic (9.50e-2)" "unprognostic (6.62e-2)" "prognostic favorable (1.84e-4)" "unprognostic (1.98e-1)" "unprognostic (3.54e-3)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (7.82e-2)" "unprognostic (2.11e-3)" "unprognostic (5.75e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.73e-2)" "unprognostic (3.42e-1)" "unprognostic (3.21e-1)" "unprognostic (1.71e-2)" CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 382.1;Distal tubular cells: 429.1;Hepatocytes: 347.2;Proximal enterocytes: 409.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Enzymes" "Cluster 50: Enterocytes - Absorption" Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" COA5 "C2orf64, FLJ27524, MGC52110, Pet191" ENSG00000183513 "Cytochrome c oxidase assembly factor 5" Q86WW8 2 98599314-98608515 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 149.3;Proximal tubular cells: 159.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057768 Uncertain Supported Mitochondria No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA057768: AB_2683521" "unprognostic (1.00e-1)" "unprognostic (4.19e-2)" "unprognostic (3.85e-2)" "unprognostic (1.67e-3)" "unprognostic (2.61e-2)" "unprognostic (7.11e-2)" "unprognostic (4.69e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.32e-3)" "unprognostic (3.71e-3)" "unprognostic (8.00e-3)" "unprognostic (3.08e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-1)" "unprognostic (4.93e-2)" "unprognostic (2.50e-1)" "prognostic favorable (1.00e-5)" COA6 C1orf31 ENSG00000168275 "Cytochrome c oxidase assembly factor 6" Q5JTJ3 1 234373456-234385080 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028588 Approved Supported Nucleoplasm,Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 61: Liver - Metabolism" "Cluster 19: Macrophages - Innate immune response" Mitochondria Nucleoplasm "HPA028588: AB_10601123" "unprognostic (6.26e-2)" "unprognostic (1.92e-1)" "unprognostic (3.05e-1)" "unprognostic (1.01e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (4.04e-3)" "unprognostic (4.89e-2)" "unprognostic (2.79e-2)" "unprognostic (6.25e-3)" "unprognostic (9.24e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (2.38e-1)" "unprognostic (5.24e-2)" "unprognostic (2.19e-1)" "prognostic favorable (7.12e-4)" COA8 "APOP-1, APOPT1, C14orf153, MGC2562" ENSG00000256053 "Cytochrome c oxidase assembly factor 8" Q96IL0 14 103562960-103607523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.2" "Group enriched" "Detected in all" 5 "Early spermatids: 519.2;Late spermatids: 1111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 36: Spermatids - Spermatogenesis" "unprognostic (1.28e-1)" "unprognostic (1.76e-1)" "unprognostic (1.46e-1)" "unprognostic (4.06e-1)" "unprognostic (1.93e-1)" "unprognostic (6.74e-3)" "prognostic unfavorable (6.34e-5)" "unprognostic (1.83e-1)" "unprognostic (7.59e-2)" "prognostic favorable (4.78e-4)" "unprognostic (2.24e-1)" "unprognostic (2.26e-1)" "unprognostic (1.43e-2)" "unprognostic (5.55e-2)" "unprognostic (2.98e-2)" "unprognostic (3.14e-1)" "unprognostic (3.99e-1)" COX10 ENSG00000006695 "Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10" Q12887 17 14069490-14231736 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Heme biosynthesis, Lipid metabolism" Transferase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 44.5;tongue: 44.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 133.0;Late spermatids: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032005, HPA032006" Supported Supported Nucleoli,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 49: Non-specific - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "Nucleoli, Cytosol" "HPA032005: AB_10603560, HPA032006: AB_10670554" "unprognostic (6.17e-2)" "unprognostic (3.14e-1)" "unprognostic (1.41e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.40e-2)" "unprognostic (6.27e-3)" "unprognostic (1.07e-1)" "unprognostic (9.46e-3)" "unprognostic (6.46e-2)" "prognostic favorable (4.32e-6)" "prognostic favorable (8.73e-4)" "unprognostic (8.82e-2)" "unprognostic (1.02e-2)" "unprognostic (8.71e-2)" COX14 "C12orf62, MGC14288" ENSG00000178449 "Cytochrome c oxidase assembly factor COX14" Q96I36 12 50112082-50120457 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 621.3;Distal tubular cells: 587.7;Proximal tubular cells: 865.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "HPA044618, HPA062014" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA044618: AB_10960419, HPA062014: AB_2684657" "unprognostic (5.71e-2)" "unprognostic (1.86e-2)" "unprognostic (1.43e-1)" "unprognostic (4.04e-1)" "unprognostic (1.87e-2)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (4.20e-3)" "prognostic unfavorable (7.90e-4)" "unprognostic (7.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.09e-3)" "unprognostic (3.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-3)" COX15 CEMCOX2 ENSG00000014919 "Cytochrome c oxidase assembly homolog COX15" Q7KZN9 10 99710868-99732127 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037727, HPA037728, HPA066096" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 16: Non-specific - RNA binding" Mitochondria Nucleoplasm "HPA037727: AB_10672391, HPA037728: AB_10672463, HPA066096: AB_2685616" "unprognostic (9.74e-2)" "unprognostic (1.20e-1)" "unprognostic (1.99e-1)" "unprognostic (6.55e-3)" "unprognostic (1.50e-2)" "unprognostic (1.34e-1)" "unprognostic (5.36e-2)" "unprognostic (2.96e-1)" "unprognostic (6.84e-2)" "unprognostic (1.76e-1)" "unprognostic (3.40e-2)" "unprognostic (8.34e-2)" "prognostic favorable (9.21e-6)" "unprognostic (2.08e-2)" "unprognostic (2.21e-2)" "unprognostic (1.86e-2)" "unprognostic (3.40e-2)" COX20 "FAM36A, FLJ43269" ENSG00000203667 "Cytochrome c oxidase assembly factor COX20" Q5RI15 1 244835616-244845057 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 491.8;Distal tubular cells: 497.6;Proximal tubular cells: 522.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043617, HPA045490" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA043617: AB_10965694, HPA045490: AB_10962869" "unprognostic (5.84e-3)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (2.86e-1)" "unprognostic (3.62e-1)" "unprognostic (3.70e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.99e-1)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (2.54e-2)" "unprognostic (3.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.02e-3)" COX6B1 "COX6B, COXG" ENSG00000126267 "Cytochrome c oxidase subunit 6B1" P14854 19 35648323-35658782 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 2453.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2506.3;Distal tubular cells: 3100.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004192 Supported Supported Mitochondria NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA004192: AB_1847180" "unprognostic (5.12e-2)" "unprognostic (1.86e-2)" "unprognostic (3.81e-2)" "unprognostic (1.22e-1)" "unprognostic (1.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.18e-1)" "unprognostic (6.16e-2)" "unprognostic (3.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.64e-1)" "unprognostic (1.88e-1)" "prognostic favorable (5.42e-4)" "unprognostic (2.10e-2)" "unprognostic (6.98e-2)" "unprognostic (5.74e-2)" "unprognostic (5.48e-3)" CYC1 UQCR4 ENSG00000179091 "Cytochrome c1" P08574 8 144095039-144097525 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 730.0;tongue: 724.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 677.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001247 Supported Approved Mitochondria NA NA 45000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 26: Intestinal epithelial cells - Absorption" Mitochondria "HPA001247: AB_1078602" "unprognostic (3.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.25e-1)" "unprognostic (6.52e-2)" "unprognostic (1.39e-1)" "unprognostic (3.92e-3)" "unprognostic (6.23e-2)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "prognostic favorable (5.89e-6)" "unprognostic (6.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-1)" "unprognostic (3.13e-2)" DGUOK dGK ENSG00000114956 "Deoxyguanosine kinase" Q16854 2 73926826-73958961 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034766, HPA057246" Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 74: Pancreatic cells - Mixed function" "HPA034766: AB_10669850, HPA057246: AB_2683381" "unprognostic (3.40e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-2)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (4.17e-2)" "unprognostic (2.14e-2)" "unprognostic (1.37e-2)" "unprognostic (4.10e-3)" "unprognostic (5.07e-2)" "unprognostic (1.41e-1)" "unprognostic (9.84e-2)" "prognostic unfavorable (8.69e-7)" "unprognostic (3.86e-1)" "unprognostic (2.21e-2)" "unprognostic (5.98e-2)" "prognostic favorable (7.47e-4)" DLD "DLDH, E3, GCSL, LAD, OGDC-E3" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107891162-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 357.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 346.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044849 Supported Approved Nucleoplasm,Mitochondria NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: Non-specific - Transcription" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoplasm "HPA044849: AB_2679111" "unprognostic (2.01e-3)" "unprognostic (2.26e-1)" "unprognostic (1.27e-2)" "unprognostic (9.27e-2)" "unprognostic (5.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (9.43e-2)" "unprognostic (7.35e-2)" "prognostic favorable (7.58e-9)" "unprognostic (4.08e-2)" "unprognostic (1.88e-1)" "unprognostic (4.45e-3)" "unprognostic (1.18e-1)" DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Intellectual disability, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.7;Excitatory neurons: 13.9;Inhibitory neurons: 15.2;Oligodendrocytes: 17.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.8" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 43: Non-specific - Cell proliferation" Mitochondria "HPA037487: AB_10672493, HPA057526: AB_2683456" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Approved Supported Vesicles,Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 44: Photoreceptor cells - Visual perception" Cytosol Vesicles "CAB009952: AB_2093533, HPA039324: AB_2676443" "unprognostic (2.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.27e-6)" "unprognostic (8.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.04e-2)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (7.48e-2)" "unprognostic (1.57e-2)" EARS2 "KIAA1970, MSE1, mtGlnRS" ENSG00000103356 "Glutamyl-tRNA synthetase 2, mitochondrial" Q5JPH6 16 23520754-23557731 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043289, HPA043633" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: Non-specific - Transcription" "Cluster 16: Non-specific - RNA binding" Mitochondria Nucleoplasm "HPA043289: AB_10963932, HPA043633: AB_10959901" "unprognostic (3.10e-2)" "unprognostic (1.60e-1)" "unprognostic (3.65e-3)" "unprognostic (4.20e-1)" "unprognostic (3.57e-1)" "unprognostic (4.64e-2)" "unprognostic (2.73e-1)" "unprognostic (2.91e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (8.09e-2)" "prognostic favorable (3.16e-6)" "unprognostic (2.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.19e-1)" "unprognostic (4.29e-2)" ELAC2 "FLJ10530, HPC2" ENSG00000006744 "ElaC ribonuclease Z 2" Q9BQ52 17 12991612-13018065 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "testis cancer: 394.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019535 Approved Supported Nucleoplasm NA NA 9500 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 49: Non-specific - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA019535: AB_1848106" "unprognostic (4.24e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "prognostic favorable (3.24e-6)" "unprognostic (8.64e-2)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.47e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-1)" "unprognostic (5.31e-3)" "unprognostic (3.09e-1)" "unprognostic (5.31e-3)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (8.09e-2)" "unprognostic (3.70e-2)" FARS2 "dJ236A3.1, FARS1, mtPheRS" ENSG00000145982 "Phenylalanyl-tRNA synthetase 2, mitochondrial" O95363 6 5261044-5829192 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 106.9;Excitatory neurons: 213.9;Inhibitory neurons: 119.7;Microglial cells: 104.0;Oligodendrocyte precursor cells: 178.6;Oligodendrocytes: 115.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018148, HPA028836" Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "HPA018148: AB_1848426, HPA028836: AB_10601377" "unprognostic (2.73e-1)" "unprognostic (4.08e-3)" "prognostic favorable (5.14e-4)" "unprognostic (2.68e-1)" "unprognostic (1.94e-2)" "unprognostic (5.34e-3)" "unprognostic (1.82e-1)" "unprognostic (4.31e-3)" "unprognostic (7.18e-2)" "unprognostic (1.02e-2)" "unprognostic (8.91e-2)" "unprognostic (2.50e-1)" "prognostic favorable (1.24e-6)" "unprognostic (2.81e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" FASTKD2 KIAA0971 ENSG00000118246 "FAST kinase domains 2" Q9NYY8 2 206765357-206796189 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067191 Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA067191: AB_2685801" "unprognostic (1.19e-1)" "unprognostic (2.45e-1)" "unprognostic (3.50e-3)" "unprognostic (1.36e-3)" "unprognostic (7.40e-2)" "unprognostic (2.69e-3)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.69e-2)" "unprognostic (2.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.38e-3)" "unprognostic (1.48e-1)" "unprognostic (6.32e-2)" "unprognostic (4.87e-2)" "unprognostic (7.18e-2)" "unprognostic (1.03e-3)" "unprognostic (3.57e-2)" FBXL4 "FBL4, FBL5" ENSG00000112234 "F-box and leucine rich repeat protein 4" Q9UKA2 6 98868535-98948006 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 92.9;Oligodendrocytes: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029140, CAB033362" Approved Supported "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 1: Thyroid gland - Transcription" "Cluster 15: Non-specific - Protein binding" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nuclear speckles" "CAB033362: AB_2103974, HPA029140: AB_10611967" "unprognostic (1.24e-1)" "unprognostic (5.10e-2)" "unprognostic (1.10e-2)" "unprognostic (1.42e-1)" "unprognostic (3.34e-2)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (3.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.68e-1)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-1)" "unprognostic (2.62e-1)" FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519755 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 209.0;Early spermatids: 247.9;Syncytiotrophoblasts: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: Non-specific - RNA binding" "Cluster 18: Non-specific - Mixed function" Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" FOXRED1 H17 ENSG00000110074 "FAD dependent oxidoreductase domain containing 1" Q96CU9 11 126269055-126278131 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039620, HPA046192" Uncertain Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 40: Plasma cells - Humoral immune response" Mitochondria "HPA039620: AB_2676602, HPA046192: AB_2679580" "prognostic unfavorable (7.36e-4)" "unprognostic (4.62e-2)" "unprognostic (2.71e-1)" "unprognostic (3.47e-3)" "unprognostic (1.76e-1)" "unprognostic (1.84e-1)" "unprognostic (9.59e-2)" "unprognostic (1.43e-1)" "unprognostic (8.14e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.01e-6)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (2.00e-1)" "unprognostic (1.94e-1)" GATB "PET112, PET112L" ENSG00000059691 "Glutamyl-tRNA amidotransferase subunit B" O75879 4 151670504-151761007 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Muller glia cells: 313.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042610 Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 68: Muller glia cells - Visual perception" Mitochondria "HPA042610: AB_10797502" "unprognostic (2.52e-1)" "unprognostic (3.33e-1)" "unprognostic (1.01e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (2.06e-1)" "unprognostic (6.76e-2)" "unprognostic (1.37e-1)" "unprognostic (8.17e-2)" "prognostic favorable (1.20e-10)" "unprognostic (1.91e-1)" "unprognostic (8.39e-2)" "unprognostic (3.09e-2)" "unprognostic (2.46e-1)" GATC "15E1.2, FLJ37000" ENSG00000257218 "Glutamyl-tRNA amidotransferase subunit C" O43716 12 120446444-120463749 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 22: Non-specific - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" "unprognostic (2.10e-1)" "unprognostic (3.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.04e-2)" "unprognostic (2.22e-1)" "unprognostic (8.46e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.68e-1)" "unprognostic (2.94e-2)" "unprognostic (1.02e-1)" "unprognostic (1.64e-1)" "unprognostic (1.02e-1)" "unprognostic (4.10e-3)" "unprognostic (1.32e-1)" "unprognostic (1.70e-1)" "unprognostic (1.12e-1)" "unprognostic (5.92e-2)" GFM1 "EFGM, EGF1, GFM, mtEF-G1" ENSG00000168827 "G elongation factor mitochondrial 1" Q96RP9 3 158644527-158695581 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034764, HPA034765, HPA061405" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondria" "Cluster 16: Non-specific - RNA binding" Mitochondria Nucleoplasm "HPA034764: AB_2674320, HPA034765: AB_10669849, HPA061405: AB_2684505" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (5.48e-3)" "unprognostic (4.48e-3)" "unprognostic (1.84e-1)" "unprognostic (3.40e-1)" "unprognostic (4.75e-2)" "unprognostic (6.05e-2)" "unprognostic (2.48e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (9.20e-4)" "unprognostic (2.79e-1)" "prognostic favorable (1.16e-7)" "unprognostic (1.62e-1)" "unprognostic (4.78e-1)" "unprognostic (3.32e-2)" "unprognostic (8.78e-2)" GFM2 "EF-G2mt, EFG2, FLJ21661" ENSG00000164347 "GTP dependent ribosome recycling factor mitochondrial 2" Q969S9 5 74721206-74767147 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036863, HPA069871" Uncertain Approved "Nucleoplasm,Midbody ring,Mitochondria" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 56: Ciliated cells - Cilium assembly" Mitochondria "Nucleoplasm, Midbody ring" "HPA036863: AB_2675354, HPA069871: " "unprognostic (2.58e-3)" "unprognostic (7.04e-2)" "unprognostic (8.54e-3)" "unprognostic (1.98e-1)" "unprognostic (4.49e-2)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (1.40e-1)" "unprognostic (3.80e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.33e-5)" "unprognostic (9.55e-2)" "unprognostic (4.15e-1)" "unprognostic (8.52e-3)" "unprognostic (9.82e-2)" GTPBP3 "FLJ14700, GTPBG3, MSS1, MTGP1, THDF1" ENSG00000130299 "GTP binding protein 3, mitochondrial" Q969Y2 19 17334920-17342731 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042158 Approved Supported Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 53: Non-specific - mRNA processing" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA042158: AB_10964400" "unprognostic (1.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (3.08e-3)" "unprognostic (1.34e-1)" "unprognostic (2.18e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (6.32e-2)" "unprognostic (1.82e-1)" "unprognostic (2.70e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (2.81e-4)" "prognostic unfavorable (1.64e-4)" "unprognostic (4.94e-3)" "unprognostic (1.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.79e-1)" HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 292.5;Hepatocytes: 314.6;Proximal enterocytes: 392.7;Proximal tubular cells: 252.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 507.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 50: Enterocytes - Absorption" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 793.3;skeletal muscle: 950.6;tongue: 1097.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria No No 61000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favorable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 280.0;Proximal tubular cells: 352.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541, HPA067080" Enhanced Enhanced Mitochondria NA NA 74000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 45: Non-specific - Cell proliferation" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA036540: AB_10673355, HPA036541: AB_2675182, HPA067080: " "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favorable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favorable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119748002-119768905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 2434.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 492.2;Enteroendocrine cells: 252.7;Hepatocytes: 1106.7;Intestinal goblet cells: 256.8;Paneth cells: 285.3;Undifferentiated cells: 232.4" "Cancer enriched" "Detected in many" 5 "liver cancer: 441.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 40.5;colorectal cancer: 64.4;prostate cancer: 43.7" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027423, HPA027442, CAB032906" Enhanced Approved Mitochondria NA NA 830000 "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Mitochondria "CAB032906: AB_2118322, HPA027423: AB_2672266, HPA027442: AB_2672277" "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "unprognostic (7.62e-2)" "unprognostic (1.49e-2)" "prognostic favorable (2.43e-7)" "unprognostic (9.68e-2)" "unprognostic (3.21e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.20e-1)" "unprognostic (6.42e-2)" "prognostic favorable (3.43e-5)" "unprognostic (9.57e-2)" "unprognostic (2.31e-1)" "unprognostic (5.00e-2)" "unprognostic (1.54e-3)" IBA57 "C1orf69, FLJ12734" ENSG00000181873 "Iron-sulfur cluster assembly factor IBA57" Q5T440 1 228165804-228182257 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Heme biosynthesis" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030555, HPA030556, HPA030557" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 6: Late spermatids - Spermatogenesis" Mitochondria "HPA030555: AB_2673522, HPA030556: AB_2673523, HPA030557: AB_10670433" "unprognostic (3.00e-2)" "unprognostic (1.71e-1)" "unprognostic (1.36e-1)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "unprognostic (8.16e-3)" "unprognostic (1.03e-1)" "unprognostic (6.11e-2)" "unprognostic (7.01e-2)" "unprognostic (8.00e-3)" "unprognostic (2.87e-2)" "unprognostic (1.61e-1)" "prognostic favorable (1.71e-9)" "unprognostic (4.94e-2)" "unprognostic (5.02e-1)" "unprognostic (5.04e-3)" "unprognostic (7.14e-2)" ISCA1 "HBLD2, hIscA, ISA1, MGC4276" ENSG00000135070 "Iron-sulfur cluster assembly 1" Q9BUE6 9 86264546-86283102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 565.4;Late spermatids: 660.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" HPA042789 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 55: Non-specific - Unknown function" "Cluster 36: Spermatids - Spermatogenesis" "HPA042789: AB_10797022" "unprognostic (1.14e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-3)" "unprognostic (6.91e-2)" "unprognostic (2.08e-1)" "unprognostic (1.00e-3)" "unprognostic (2.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (2.66e-1)" "prognostic favorable (3.83e-4)" "unprognostic (4.06e-1)" "unprognostic (1.24e-1)" "unprognostic (1.09e-2)" "unprognostic (3.31e-1)" ISCA2 "HBLD1, ISA2" ENSG00000165898 "Iron-sulfur cluster assembly 2" Q86U28 14 74493756-74497106 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030492 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA030492: AB_10603772" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "unprognostic (5.73e-2)" "unprognostic (5.62e-2)" "unprognostic (2.51e-1)" "unprognostic (5.89e-3)" "unprognostic (6.03e-3)" "unprognostic (7.98e-2)" "unprognostic (1.66e-1)" "unprognostic (2.59e-2)" "unprognostic (1.31e-2)" "unprognostic (2.21e-1)" "prognostic favorable (1.68e-7)" "unprognostic (3.98e-2)" "unprognostic (1.47e-1)" "prognostic favorable (8.98e-5)" "unprognostic (5.23e-2)" ISCU "hnifU, ISU2, NIFUN" ENSG00000136003 "Iron-sulfur cluster assembly enzyme" Q9H1K1 12 108562582-108569368 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 755.5;Distal tubular cells: 1483.3;Late spermatids: 963.1;Proximal tubular cells: 1208.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "CAB006329, HPA038602, HPA057592" Approved Supported Mitochondria,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" "Mitochondria, Cytosol" "CAB006329: AB_425907, HPA038602: AB_2676109, HPA057592: AB_2683478" "unprognostic (1.72e-1)" "prognostic favorable (4.90e-7)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (2.43e-1)" "unprognostic (3.15e-2)" "unprognostic (1.33e-1)" "unprognostic (6.69e-3)" "unprognostic (1.14e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-3)" "unprognostic (2.49e-2)" "prognostic favorable (2.73e-7)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-3)" "prognostic favorable (6.12e-4)" KIF1C "SAX2, SPAX2, SPG58" ENSG00000129250 "Kinesin family member 1C" O43896 17 4997950-5028401 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 244.8;choroid plexus: 142.7;heart muscle: 185.0;skeletal muscle: 561.0;tongue: 389.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 342.4;Distal enterocytes: 141.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024602, HPA045020" Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 49: Non-specific - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA024602: AB_1852480, HPA045020: AB_2679187" "unprognostic (3.89e-2)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-1)" "unprognostic (8.97e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (6.69e-2)" "unprognostic (8.31e-2)" "unprognostic (1.45e-1)" "unprognostic (4.90e-3)" "prognostic favorable (2.26e-9)" "unprognostic (1.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.41e-1)" "unprognostic (7.10e-3)" LARS1 "FLJ10595, FLJ21788, HSPC192, LARS, LEUS, RNTLS" ENSG00000133706 "Leucyl-tRNA synthetase 1" Q9P2J5 5 146110566-146182696 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036424, HPA040881" Supported Approved "Nuclear bodies,Cytosol" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 57: Non-specific - Translation" "Cluster 16: Non-specific - RNA binding" "Nuclear bodies, Cytosol" "HPA036424: AB_10670102, HPA040881: AB_2677185" "unprognostic (2.20e-2)" "unprognostic (1.87e-1)" "unprognostic (2.38e-3)" "unprognostic (1.92e-1)" "unprognostic (2.69e-1)" "unprognostic (3.39e-1)" "prognostic unfavorable (3.78e-5)" "unprognostic (8.17e-2)" "unprognostic (2.72e-1)" "unprognostic (6.80e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.96e-2)" LDLR LDLCQ2 ENSG00000130164 "Low density lipoprotein receptor" P01130 19 11089462-11133820 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 112.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 272.7;Alveolar cells type 2: 420.9;Suprabasal keratinocytes: 288.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 46.0" "Lineage enriched" "Detected in many" 9 "granulocytes: 46.0" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Heart muscle - Endothelial cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009647, HPA013159" Approved NA NA 23000000 "Cluster 38: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 41: Alveolar cells - Lung function" "HPA009647: AB_1079243, HPA013159: AB_1852775" "unprognostic (4.39e-1)" "unprognostic (1.93e-3)" "unprognostic (2.52e-1)" "unprognostic (2.76e-1)" "unprognostic (4.03e-2)" "unprognostic (1.17e-1)" "unprognostic (6.71e-2)" "unprognostic (4.26e-2)" "unprognostic (3.73e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (1.62e-1)" "unprognostic (2.78e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.43e-4)" LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39459004-39485109 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria Yes No "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Mixed function" Nucleoplasm Mitochondria "HPA018842: AB_1852864, HPA019076: AB_1852866" "unprognostic (3.61e-1)" "unprognostic (1.89e-1)" "unprognostic (8.44e-2)" "unprognostic (2.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (4.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.46e-3)" "unprognostic (3.80e-2)" "prognostic favorable (4.11e-7)" "unprognostic (9.41e-3)" "unprognostic (2.35e-1)" "unprognostic (5.45e-2)" "unprognostic (6.98e-2)" LRPPRC "GP130, LRP130, LSFC" ENSG00000138095 "Leucine rich pentatricopeptide repeat containing" P42704 2 43886224-43995989 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033786, HPA036408, HPA036409" Enhanced Enhanced Mitochondria No No 210000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" Mitochondria "CAB033786: AB_2137450, HPA036408: AB_10670438, HPA036409: AB_2675108" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-3)" "prognostic unfavorable (1.72e-5)" "unprognostic (1.68e-1)" "unprognostic (8.34e-3)" "prognostic unfavorable (2.31e-7)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.44e-3)" "unprognostic (7.68e-2)" "prognostic favorable (6.65e-6)" "unprognostic (9.07e-2)" "unprognostic (1.92e-1)" "unprognostic (1.12e-1)" "unprognostic (5.00e-2)" LYRM4 "C6orf149, CGI-203, ISD11" ENSG00000214113 "LYR motif containing 4" Q9HD34 6 5103629-5260950 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Testis - Early spermatids" HPA030362 Approved Supported "Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 15: Non-specific - Protein binding" "Cluster 39: Non-specific - Translation" "Nuclear bodies" "HPA030362: AB_10601546" "unprognostic (2.41e-2)" "unprognostic (3.72e-2)" "unprognostic (7.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.30e-1)" "unprognostic (8.73e-2)" "unprognostic (1.85e-3)" "unprognostic (4.58e-2)" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.03e-1)" "unprognostic (2.26e-1)" "unprognostic (2.79e-3)" "unprognostic (1.43e-1)" "unprognostic (2.76e-1)" "unprognostic (9.80e-2)" "unprognostic (5.23e-1)" LYRM7 "C5orf31, FLJ20796, MZM1L" ENSG00000186687 "LYR motif containing 7" Q5U5X0 5 131170944-131205428 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 33.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 117.5;Early spermatids: 155.4;Late spermatids: 213.6;Spermatocytes: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050053 Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 57: Non-specific - Translation" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "HPA050053: AB_2680999" "unprognostic (1.88e-2)" "unprognostic (2.89e-1)" "unprognostic (3.16e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-1)" "unprognostic (5.90e-2)" "unprognostic (1.02e-1)" "unprognostic (9.03e-2)" "unprognostic (2.50e-3)" "unprognostic (1.23e-1)" "unprognostic (1.50e-2)" "unprognostic (3.03e-1)" "prognostic favorable (9.84e-6)" "unprognostic (6.61e-2)" "unprognostic (2.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.20e-1)" MARS2 "mtMetRS, SPAX3" ENSG00000247626 "Methionyl-tRNA synthetase 2, mitochondrial" Q96GW9 2 197705369-197708395 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 13.2;Suprabasal keratinocytes: 13.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035589, HPA035590" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA035589: AB_10601870, HPA035590: AB_2674693" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.12e-4)" "unprognostic (2.99e-2)" "unprognostic (2.35e-2)" "unprognostic (1.53e-1)" "unprognostic (7.61e-2)" "unprognostic (1.04e-1)" "unprognostic (9.54e-2)" "unprognostic (1.86e-3)" "prognostic favorable (6.14e-5)" "unprognostic (1.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.47e-2)" "unprognostic (8.74e-2)" MFF "C2orf33, GL004" ENSG00000168958 "Mitochondrial fission factor" Q9GZY8 2 227325151-227357836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 998.2;Late spermatids: 1810.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010968, HPA074625" Enhanced Supported Mitochondria No No 62000 "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 61: Liver - Metabolism" "Cluster 6: Late spermatids - Spermatogenesis" Mitochondria "HPA010968: AB_1845714, HPA074625: AB_2686704" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-2)" "unprognostic (1.73e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.20e-4)" "unprognostic (3.07e-2)" "unprognostic (1.32e-1)" "unprognostic (6.07e-2)" "unprognostic (3.00e-2)" "unprognostic (6.24e-3)" "unprognostic (5.50e-2)" "unprognostic (1.00e-1)" "unprognostic (2.70e-2)" "unprognostic (1.51e-1)" "unprognostic (3.22e-1)" MGME1 "bA504H3.4, C20orf72, DDK1" ENSG00000125871 "Mitochondrial genome maintenance exonuclease 1" Q9BQP7 20 17969018-17991122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040913 Approved Supported Mitochondria NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 43: Non-specific - Cell proliferation" Mitochondria "HPA040913: AB_10962835" "unprognostic (5.81e-3)" "unprognostic (5.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-3)" "unprognostic (5.42e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (5.31e-2)" "unprognostic (7.05e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (8.70e-2)" "unprognostic (6.89e-2)" MICOS13 "C19orf70, MIC13, P117, QIL1" ENSG00000174917 "Mitochondrial contact site and cristae organizing system subunit 13" Q5XKP0 19 5678421-5680516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Late spermatids: 3956.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042672 Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 53: Non-specific - mRNA processing" "Cluster 51: Late spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA042672: AB_10794531" "unprognostic (9.54e-2)" "unprognostic (4.90e-3)" "unprognostic (3.04e-1)" "unprognostic (3.21e-3)" "unprognostic (1.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (2.53e-3)" "unprognostic (2.14e-2)" "unprognostic (9.32e-2)" "unprognostic (2.50e-2)" "unprognostic (1.57e-1)" "prognostic favorable (7.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.94e-2)" "unprognostic (2.27e-1)" "unprognostic (5.47e-2)" MICU1 "CALC, CBARA1, EFHA3, FLJ12684" ENSG00000107745 "Mitochondrial calcium uptake 1" Q9BPX6 10 72367327-72626191 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" Allergen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 182.8;Inhibitory neurons: 201.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037479, HPA037480" Approved Supported Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 37: Neurons - Neuronal signaling" Mitochondria "HPA037479: AB_2675495, HPA037480: AB_10696934" "unprognostic (8.18e-2)" "unprognostic (6.98e-3)" "unprognostic (6.71e-2)" "unprognostic (8.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (8.91e-2)" "unprognostic (3.60e-2)" "unprognostic (2.96e-3)" "unprognostic (3.38e-2)" "unprognostic (7.43e-2)" "unprognostic (2.23e-2)" "prognostic favorable (4.66e-7)" "unprognostic (1.70e-1)" "unprognostic (1.55e-1)" "unprognostic (5.35e-2)" "unprognostic (6.70e-2)" MIEF2 "MGC23130, MiD49, SMCR7" ENSG00000177427 "Mitochondrial elongation factor 2" Q96C03 17 18260597-18266552 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042334 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 49: Non-specific - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" "HPA042334: AB_10794418" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" "unprognostic (7.56e-3)" "unprognostic (1.30e-1)" "unprognostic (8.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-2)" "prognostic favorable (1.75e-7)" "unprognostic (4.68e-2)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (3.06e-2)" MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 133.4;Oligodendrocytes: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 739.7;tongue: 559.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1280.7;Distal tubular cells: 1296.8;Proximal tubular cells: 522.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045119, HPA055790" Enhanced Enhanced Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein binding" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA045119: AB_10960421, HPA055790: AB_2682923" "unprognostic (3.30e-2)" "prognostic favorable (1.45e-4)" "unprognostic (5.24e-3)" "unprognostic (1.68e-1)" "unprognostic (3.17e-2)" "unprognostic (2.85e-2)" "unprognostic (7.61e-2)" "prognostic favorable (1.29e-4)" "unprognostic (3.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (5.64e-2)" "prognostic favorable (4.79e-11)" "unprognostic (4.13e-2)" "unprognostic (1.03e-1)" "unprognostic (7.48e-2)" "unprognostic (8.45e-2)" MPV17 SYM1 ENSG00000115204 "Mitochondrial inner membrane protein MPV17" P39210 2 27309492-27325680 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 16: Non-specific - RNA binding" "unprognostic (9.34e-3)" "unprognostic (2.70e-1)" "unprognostic (9.50e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (6.99e-6)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (1.56e-1)" "unprognostic (2.22e-1)" "unprognostic (1.48e-1)" "unprognostic (1.44e-3)" "unprognostic (2.59e-3)" "unprognostic (2.52e-1)" "unprognostic (5.10e-3)" "unprognostic (4.62e-2)" MRM2 "FJH1, FTSJ2, RRMJ2" ENSG00000122687 "Mitochondrial rRNA methyltransferase 2" Q9UI43 7 2234195-2242205 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 4.5;Basal squamous epithelial cells: 6.3;Erythroid cells: 6.8;Excitatory neurons: 4.8;Inhibitory neurons: 4.3;Microglial cells: 6.4;Oligodendrocyte precursor cells: 4.8;Oligodendrocytes: 4.4;Plasma cells: 8.7;Squamous epithelial cells: 5.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019826, HPA049622" Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 63: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "HPA019826: AB_2670282, HPA049622: AB_2680834" "unprognostic (8.05e-2)" "unprognostic (1.65e-1)" "unprognostic (2.14e-2)" "unprognostic (2.59e-1)" "unprognostic (1.49e-2)" "unprognostic (2.50e-3)" "prognostic unfavorable (5.21e-6)" "unprognostic (8.49e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (9.99e-2)" "unprognostic (8.33e-2)" "unprognostic (1.69e-1)" "unprognostic (2.37e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (1.48e-1)" MRPL12 "MRPL7, MRPL7/L12, RPML12" ENSG00000262814 "Mitochondrial ribosomal protein L12" P52815 17 81703367-81707517 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 330.6;Undifferentiated cells: 399.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022853, HPA023043" Supported Supported Mitochondria NA NA 49000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: RS4;11 - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" Mitochondria "HPA022853: AB_1854099, HPA023043: AB_1854100" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (6.59e-2)" "unprognostic (1.66e-2)" "unprognostic (9.52e-2)" "unprognostic (5.97e-2)" "unprognostic (5.97e-3)" "prognostic unfavorable (2.35e-4)" "unprognostic (1.78e-1)" "unprognostic (6.47e-3)" "unprognostic (8.17e-2)" "unprognostic (3.07e-1)" "unprognostic (8.77e-3)" "unprognostic (3.41e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (9.26e-2)" MRPL3 "MRL3, RPML3" ENSG00000114686 "Mitochondrial ribosomal protein L3" P09001 3 131462212-131502983 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043665, HPA060132" Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondria" "Cluster 16: Non-specific - RNA binding" "HPA043665: AB_2678606, HPA060132: AB_2684209" "unprognostic (1.75e-2)" "unprognostic (7.23e-2)" "unprognostic (2.61e-2)" "unprognostic (1.61e-3)" "unprognostic (7.83e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.33e-7)" "unprognostic (1.54e-1)" "unprognostic (8.23e-2)" "prognostic favorable (1.36e-4)" "prognostic unfavorable (3.51e-6)" "unprognostic (2.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (3.29e-1)" MRPL44 "FLJ12701, FLJ13990" ENSG00000135900 "Mitochondrial ribosomal protein L44" Q9H9J2 2 223957463-223967714 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038147, HPA038148" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Mitochondria" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" Mitochondria "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA038147: AB_10671521, HPA038148: AB_2675863" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (3.38e-2)" "unprognostic (3.00e-1)" "unprognostic (7.05e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.16e-2)" "unprognostic (3.32e-1)" "unprognostic (7.65e-2)" "unprognostic (8.33e-2)" "unprognostic (6.65e-2)" "prognostic favorable (2.02e-4)" "unprognostic (2.47e-2)" "unprognostic (1.14e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-1)" MRPS14 HSMRPS14 ENSG00000120333 "Mitochondrial ribosomal protein S14" O60783 1 175010789-175023425 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051087 Uncertain Supported "Nuclear membrane,Mitochondria" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 18: Non-specific - RNA binding" "Cluster 16: Non-specific - RNA binding" Mitochondria "Nuclear membrane" "HPA051087: AB_2681339" "unprognostic (9.24e-2)" "unprognostic (6.37e-2)" "unprognostic (1.50e-1)" "unprognostic (3.46e-1)" "unprognostic (3.44e-2)" "unprognostic (5.39e-2)" "unprognostic (1.61e-2)" "unprognostic (3.01e-2)" "unprognostic (7.32e-2)" "unprognostic (4.85e-2)" "unprognostic (7.67e-2)" "unprognostic (3.10e-2)" "unprognostic (1.31e-3)" "unprognostic (1.67e-1)" "unprognostic (8.04e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-2)" MRPS16 CGI-132 ENSG00000182180 "Mitochondrial ribosomal protein S16" Q9Y3D3 10 73248843-73252693 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050081, HPA054538" Supported Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 16: Non-specific - RNA binding" "Mitochondria, Cytosol" "HPA050081: AB_2681007, HPA054538: AB_2682519" "unprognostic (9.19e-2)" "unprognostic (5.19e-2)" "unprognostic (2.34e-1)" "unprognostic (1.26e-2)" "unprognostic (1.23e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (4.57e-5)" "unprognostic (1.68e-2)" "unprognostic (6.44e-2)" "unprognostic (2.98e-2)" "unprognostic (3.21e-2)" "unprognostic (2.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.17e-2)" "unprognostic (1.24e-1)" "unprognostic (1.20e-1)" "unprognostic (5.84e-2)" MRPS2 CGI-91 ENSG00000122140 "Mitochondrial ribosomal protein S2" Q9Y399 9 135499984-135504673 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029487, HPA057261" Approved Supported Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 55: Non-specific - Unknown function" "Cluster 14: Endometrium - Transcription regulation" Mitochondria "HPA029487: , HPA057261: AB_2683385" "unprognostic (3.18e-3)" "unprognostic (9.42e-3)" "unprognostic (1.46e-1)" "unprognostic (7.81e-2)" "unprognostic (3.55e-1)" "unprognostic (8.45e-2)" "unprognostic (1.63e-1)" "unprognostic (5.63e-3)" "unprognostic (3.83e-1)" "unprognostic (2.90e-2)" "unprognostic (4.81e-2)" "unprognostic (7.58e-2)" "prognostic favorable (6.96e-9)" "unprognostic (2.74e-2)" "unprognostic (1.06e-1)" "unprognostic (8.29e-2)" "unprognostic (2.24e-1)" MRPS22 "C3orf5, GIBT, GK002, MRP-S22" ENSG00000175110 "Mitochondrial ribosomal protein S22" P82650 3 139005806-139357223 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006083, HPA007830" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondria" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA006083: AB_1854122, HPA007830: AB_1854123" "unprognostic (8.38e-2)" "unprognostic (1.52e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (5.22e-3)" "unprognostic (5.45e-3)" "unprognostic (4.85e-2)" "unprognostic (2.18e-2)" "unprognostic (2.78e-2)" "unprognostic (4.49e-3)" "prognostic unfavorable (1.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.22e-3)" "unprognostic (2.56e-2)" "unprognostic (1.49e-1)" "unprognostic (1.77e-1)" "unprognostic (3.40e-1)" MRPS23 "CGI-138, HSPC329, MRP-S23" ENSG00000181610 "Mitochondrial ribosomal protein S23" Q9Y3D9 17 57834781-57850056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 232.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023453 Supported Supported "Nuclear membrane,Mitochondria" No No "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 70: Basal prostatic cells - Lipid metabolism" Mitochondria "Nuclear membrane" "HPA023453: AB_1854125" "unprognostic (3.84e-3)" "unprognostic (3.36e-1)" "unprognostic (1.75e-2)" "unprognostic (2.00e-2)" "unprognostic (7.96e-2)" "unprognostic (3.06e-3)" "prognostic unfavorable (9.52e-4)" "unprognostic (3.71e-1)" "unprognostic (7.92e-2)" "unprognostic (2.63e-3)" "unprognostic (1.39e-2)" "unprognostic (8.74e-2)" "unprognostic (3.74e-2)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "unprognostic (2.75e-3)" "unprognostic (2.83e-1)" MRPS25 "DKFZp313H0817, FLJ00023, MRP-S25, RPMS25" ENSG00000131368 "Mitochondrial ribosomal protein S25" P82663 3 15042460-15065317 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 360.8;Late spermatids: 1332.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043490 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 5: Non-specific - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" Mitochondria "HPA043490: AB_10794888" "unprognostic (3.98e-2)" "unprognostic (5.36e-2)" "unprognostic (4.58e-3)" "unprognostic (1.24e-2)" "unprognostic (4.66e-2)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (4.93e-3)" "unprognostic (2.23e-1)" "unprognostic (2.10e-1)" "unprognostic (6.29e-2)" "unprognostic (2.68e-3)" "prognostic favorable (3.60e-7)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (5.06e-2)" "unprognostic (2.91e-3)" MRPS28 "HSPC007, MRP-S28, MRPS35" ENSG00000147586 "Mitochondrial ribosomal protein S28" Q9Y2Q9 8 79918717-80030289 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 158.6;Proximal tubular cells: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027202 Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA027202: AB_1854126" "unprognostic (3.63e-3)" "unprognostic (6.41e-2)" "unprognostic (9.61e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-3)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (4.55e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "prognostic favorable (1.20e-6)" "unprognostic (4.48e-2)" "unprognostic (3.13e-1)" "unprognostic (1.18e-1)" "unprognostic (7.18e-2)" MRPS34 "MGC2616, MRP-S12" ENSG00000074071 "Mitochondrial ribosomal protein S34" P82930 16 1771890-1773150 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042112 Supported Supported Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: Non-specific - Transcription" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA042112: AB_10796899" "unprognostic (2.02e-1)" "unprognostic (4.83e-2)" "unprognostic (6.79e-2)" "unprognostic (3.42e-2)" "unprognostic (2.27e-1)" "unprognostic (9.59e-2)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (3.03e-1)" "unprognostic (2.22e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (3.52e-1)" "unprognostic (1.37e-2)" "unprognostic (6.60e-2)" "unprognostic (3.18e-1)" "unprognostic (5.44e-2)" MRPS7 "MRP-S, RP-S7, RPMS7" ENSG00000125445 "Mitochondrial ribosomal protein S7" Q9Y2R9 17 75261674-75266376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 472.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022522, HPA023007" Supported Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" Mitochondria "HPA022522: AB_1854131, HPA023007: AB_1854132" "unprognostic (1.24e-1)" "unprognostic (4.74e-2)" "prognostic favorable (1.12e-4)" "unprognostic (5.82e-3)" "unprognostic (3.62e-2)" "unprognostic (5.05e-3)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (4.95e-2)" "unprognostic (8.56e-3)" "unprognostic (1.03e-1)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (8.56e-2)" "unprognostic (1.76e-1)" "unprognostic (4.15e-1)" MT-ATP6 "ATP6, ATPase-6, MTATP6, RP, Su6m" ENSG00000198899 "Mitochondrially encoded ATP synthase membrane subunit 6" P00846 MT 8527-9207 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Cardiomyopathy, Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, Neuropathy, Primary mitochondrial disease, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 240231.8" "Cell type enhanced" "Detected in all" "Bipolar cells: 68183.5;Cardiomyocytes: 49112.5;Cone photoreceptor cells: 42181.9;Horizontal cells: 36532.8;Rod photoreceptor cells: 54767.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 15099.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 15099.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 9: Neurons - Nervous system development" "unprognostic (2.97e-1)" "unprognostic (4.16e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" "unprognostic (8.45e-3)" "unprognostic (1.66e-1)" "prognostic favorable (3.79e-4)" "unprognostic (6.47e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-2)" "prognostic favorable (7.64e-4)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (1.46e-1)" "unprognostic (1.37e-1)" "unprognostic (3.56e-1)" "unprognostic (2.52e-3)" MT-ATP8 "A6L, ATP8, MTATP8" ENSG00000228253 "Mitochondrially encoded ATP synthase membrane subunit 8" P03928 MT 8366-8572 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 350376.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 2595.9;Cardiomyocytes: 10320.6;Gastric mucus-secreting cells: 2250.1;Squamous epithelial cells: 1920.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 10572.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 10572.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (1.54e-1)" "unprognostic (4.12e-2)" "unprognostic (3.95e-2)" "unprognostic (2.56e-1)" "unprognostic (3.07e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.56e-5)" "unprognostic (5.17e-2)" "unprognostic (6.61e-2)" "unprognostic (2.52e-3)" "unprognostic (8.26e-2)" "unprognostic (1.30e-2)" "unprognostic (1.10e-1)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (2.62e-1)" "unprognostic (1.63e-2)" MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Deafness, Disease variant, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 222644.8;heart muscle: 255389.3" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 67670.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016241, HPA069328" Enhanced Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "CAB016241: AB_2229888, HPA069328: AB_2686122" "unprognostic (4.39e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.21e-1)" "unprognostic (1.59e-1)" "unprognostic (3.31e-1)" "prognostic favorable (2.29e-4)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (1.20e-2)" "unprognostic (6.60e-2)" "unprognostic (2.83e-2)" "unprognostic (5.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.15e-2)" "unprognostic (2.44e-2)" MT-CO2 "CO2, COX2, MTCO2" ENSG00000198712 "Mitochondrially encoded cytochrome c oxidase II" P00403 MT 7586-8269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 164780.5;heart muscle: 210840.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 78921.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016243, HPA051505, HPA054758" Enhanced NA NA 240000 "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" "CAB016243: AB_2066366, HPA051505: AB_2681511, HPA054758: AB_2682595" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (2.77e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.06e-1)" "unprognostic (3.39e-1)" "unprognostic (2.72e-3)" "prognostic favorable (7.10e-4)" "unprognostic (1.25e-1)" "unprognostic (9.30e-2)" "unprognostic (3.05e-1)" "unprognostic (1.70e-1)" "unprognostic (9.50e-2)" "unprognostic (3.72e-3)" MT-CO3 "CO3, COIII, COX3, MTCO3" ENSG00000198938 "Mitochondrially encoded cytochrome c oxidase III" P00414 MT 9207-9990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 189825.4;heart muscle: 231090.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 84798.7;Horizontal cells: 59830.8;Rod photoreceptor cells: 57689.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042788 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 9: Neurons - Nervous system development" "HPA042788: AB_10793985" "unprognostic (2.38e-1)" "unprognostic (5.24e-2)" "unprognostic (1.71e-1)" "unprognostic (1.88e-1)" "unprognostic (3.04e-1)" "unprognostic (2.93e-1)" "prognostic favorable (2.01e-4)" "unprognostic (1.18e-1)" "unprognostic (1.45e-2)" "unprognostic (1.05e-2)" "prognostic favorable (1.04e-4)" "unprognostic (1.05e-1)" "unprognostic (8.80e-3)" "unprognostic (2.75e-2)" "unprognostic (1.20e-1)" "unprognostic (9.29e-2)" "unprognostic (1.33e-2)" MT-CYB "COB, CYTB, MTCYB, UQCR3" ENSG00000198727 "Mitochondrially encoded cytochrome b" P00156 MT 14747-15887 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Cataract, Deafness, Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 130283.4" "Cell type enhanced" "Detected in all" "Bipolar cells: 61574.2;Cardiomyocytes: 60359.4;Rod photoreceptor cells: 38637.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032215, HPA068400, HPA074796" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "CAB032215: AB_2261378, HPA068400: AB_2685982, HPA074796: " "unprognostic (4.50e-1)" "unprognostic (2.56e-1)" "unprognostic (9.12e-2)" "unprognostic (3.88e-2)" "unprognostic (9.22e-2)" "unprognostic (3.50e-1)" "prognostic favorable (5.96e-4)" "unprognostic (1.63e-2)" "unprognostic (8.53e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-3)" "unprognostic (6.09e-2)" "unprognostic (1.40e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (4.09e-2)" "unprognostic (1.54e-2)" MT-ND1 "MTND1, NAD1, ND1" ENSG00000198888 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1" P03886 MT 3307-4262 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Alzheimer disease, Amyloidosis, Diabetes mellitus, Disease variant, Epilepsy, FDA approved drug targets, Leber hereditary optic neuropathy, MELAS syndrome, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 111350.7;heart muscle: 127951.9" "Cell type enhanced" "Detected in all" "Bipolar cells: 21963.9;Cardiomyocytes: 30786.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 9432.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 9432.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033779, HPA066847" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" "CAB033779: AB_2149736, HPA066847: " "prognostic favorable (3.63e-4)" "unprognostic (3.55e-1)" "unprognostic (3.77e-2)" "unprognostic (3.65e-1)" "unprognostic (3.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.95e-3)" "unprognostic (5.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.05e-2)" "prognostic favorable (3.26e-4)" "unprognostic (8.67e-2)" "unprognostic (8.66e-2)" "unprognostic (3.24e-2)" "unprognostic (1.42e-2)" "unprognostic (3.99e-2)" "unprognostic (2.85e-2)" MT-ND2 "MTND2, NAD2, ND2" ENSG00000198763 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2" P03891 MT 4470-5511 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Alzheimer disease, Amyloidosis, Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 101525.8;heart muscle: 130517.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 33265.3;Proximal enterocytes: 18614.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 16754.8" "Lineage enriched" "Detected in all" 10 "granulocytes: 16754.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (5.82e-3)" "unprognostic (1.58e-2)" "unprognostic (1.53e-2)" "unprognostic (1.36e-1)" "unprognostic (4.77e-1)" "unprognostic (4.79e-2)" "unprognostic (9.56e-3)" "unprognostic (3.74e-2)" "unprognostic (2.18e-1)" "unprognostic (3.38e-3)" "unprognostic (4.55e-3)" "unprognostic (3.79e-2)" "unprognostic (4.35e-2)" "unprognostic (3.94e-2)" "unprognostic (2.11e-1)" "unprognostic (5.92e-2)" "unprognostic (4.35e-2)" MT-ND3 "MTND3, NAD3, ND3" ENSG00000198840 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3" P03897 MT 10059-10404 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 184151.1" "Cell type enhanced" "Detected in all" "Bipolar cells: 23877.6;Cardiomyocytes: 24734.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063296 Enhanced Uncertain Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 17: Granulosa cells - Transcription regulation" Cytosol "HPA063296: AB_2684978" "unprognostic (1.71e-2)" "unprognostic (1.05e-1)" "unprognostic (8.10e-2)" "unprognostic (3.07e-1)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "prognostic favorable (4.63e-5)" "unprognostic (2.45e-2)" "unprognostic (7.13e-2)" "unprognostic (8.85e-2)" "unprognostic (1.76e-3)" "unprognostic (1.74e-1)" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (1.19e-1)" "unprognostic (2.07e-1)" "unprognostic (5.65e-3)" MT-ND4 "LHON, MTND4, NAD4, ND4" ENSG00000198886 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4" P03905 MT 10760-12137 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Dystonia, Leber hereditary optic neuropathy, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 196536.0" "Cell type enhanced" "Detected in all" "Bipolar cells: 58448.2;Cardiomyocytes: 106696.0;Rod photoreceptor cells: 47132.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13456.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053928 Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA053928: AB_2682313" "unprognostic (8.39e-2)" "unprognostic (1.83e-1)" "unprognostic (7.29e-2)" "unprognostic (9.54e-2)" "unprognostic (5.41e-2)" "unprognostic (3.78e-2)" "unprognostic (2.50e-3)" "unprognostic (8.16e-2)" "unprognostic (1.45e-1)" "prognostic favorable (1.76e-4)" "unprognostic (1.01e-2)" "unprognostic (7.23e-2)" "unprognostic (2.79e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (3.14e-2)" "unprognostic (4.24e-2)" MT-ND4L "MTND4L, NAD4L, ND4L" ENSG00000212907 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L" P03901 MT 10470-10766 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 132930.7;heart muscle: 145078.7" "Cell type enriched" "Detected in all" 5 "Cardiomyocytes: 27304.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075648 Approved Centrosome,Mitochondria,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "Centrosome, Cytosol" "HPA075648: AB_2686760" "unprognostic (5.81e-2)" "unprognostic (3.46e-2)" "unprognostic (2.76e-2)" "unprognostic (7.91e-2)" "unprognostic (5.64e-2)" "unprognostic (1.05e-1)" "prognostic favorable (4.47e-4)" "unprognostic (1.97e-1)" "unprognostic (4.04e-2)" "unprognostic (4.63e-3)" "unprognostic (6.61e-2)" "unprognostic (7.38e-3)" "unprognostic (1.39e-1)" "unprognostic (3.09e-1)" "unprognostic (3.73e-1)" "unprognostic (2.97e-2)" "unprognostic (5.68e-2)" MT-ND5 "MTND5, NAD5, ND5" ENSG00000198786 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5" P03915 MT 12337-14148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 25147.7;heart muscle: 26116.9;skeletal muscle: 25697.4" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 32207.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (2.87e-1)" "unprognostic (3.18e-2)" "unprognostic (3.00e-1)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-3)" "unprognostic (5.09e-3)" "unprognostic (1.06e-2)" "unprognostic (3.01e-1)" "unprognostic (3.29e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.31e-5)" "unprognostic (9.93e-3)" "unprognostic (8.75e-2)" "unprognostic (1.26e-2)" "unprognostic (3.68e-2)" MT-ND6 "MTND6, NAD6, ND6" ENSG00000198695 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6" P03923 MT 14149-14673 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Dystonia, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 35802.7;skeletal muscle: 57879.2" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 12019.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (1.96e-1)" "unprognostic (3.27e-1)" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (1.22e-2)" "unprognostic (1.03e-3)" "unprognostic (6.02e-3)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (6.06e-3)" "unprognostic (2.91e-1)" "prognostic favorable (8.91e-6)" "unprognostic (3.64e-2)" "unprognostic (1.42e-2)" "unprognostic (1.15e-2)" "unprognostic (2.92e-2)" MTFMT FMT1 ENSG00000103707 "Mitochondrial methionyl-tRNA formyltransferase" Q96DP5 15 65001512-65029639 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040710 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 35: Non-specific - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA040710: AB_10794879" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (9.28e-3)" "unprognostic (4.35e-2)" "unprognostic (1.28e-1)" "unprognostic (1.42e-2)" "unprognostic (6.63e-2)" "unprognostic (2.02e-1)" "unprognostic (6.95e-2)" "unprognostic (2.18e-2)" "unprognostic (2.41e-2)" "unprognostic (1.78e-1)" "prognostic favorable (3.31e-8)" "unprognostic (2.75e-2)" "unprognostic (4.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.85e-2)" MTO1 ENSG00000135297 "Mitochondrial tRNA translation optimization 1" Q9Y2Z2 6 73461578-73509236 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 141.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030230, HPA030232" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein binding" "Cluster 49: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA030230: AB_10598910, HPA030232: AB_10600891" "unprognostic (2.17e-2)" "unprognostic (5.29e-2)" "unprognostic (1.05e-2)" "unprognostic (3.22e-2)" "unprognostic (6.47e-2)" "unprognostic (8.58e-2)" "unprognostic (6.28e-2)" "unprognostic (5.48e-2)" "unprognostic (2.97e-1)" "unprognostic (2.12e-3)" "unprognostic (9.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.67e-1)" "unprognostic (8.08e-3)" "unprognostic (1.64e-1)" MTPAP "FLJ10486, PAPD1, SPAX4, TENT6" ENSG00000107951 "Mitochondrial poly(A) polymerase" Q9NVV4 10 30309801-30374448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transcription" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.8" "Cell type enriched" "Detected in all" 4 "Early spermatids: 196.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038620, HPA058232" Approved Supported Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Mitochondria "Nucleoplasm, Vesicles" "HPA038620: AB_10673015, HPA058232: AB_2683646" "unprognostic (2.76e-2)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (3.05e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.16e-1)" "unprognostic (2.04e-1)" "unprognostic (4.78e-2)" "unprognostic (1.77e-1)" "unprognostic (3.56e-2)" "unprognostic (9.02e-2)" "unprognostic (6.28e-3)" "unprognostic (3.77e-1)" "unprognostic (1.14e-2)" "unprognostic (4.39e-2)" NADK2 "C5orf33, FLJ30596, MNADK, NADKD1" ENSG00000152620 "NAD kinase 2, mitochondrial" Q4G0N4 5 36192589-36242279 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "liver: 328.0" "Group enriched" "Detected in all" 6 "Astrocytes: 102.2;Early spermatids: 385.1;Hepatocytes: 210.8;Late spermatids: 163.2" "Cancer enhanced" "Detected in all" "liver cancer: 36.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038366, HPA038367, HPA061492" Enhanced Supported Mitochondria NA NA 30000 "Cluster 24: B-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 40: Non-specific - Enzymes" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Mitochondria "HPA038366: AB_2675977, HPA038367: AB_10672743, HPA061492: AB_2684538" "unprognostic (1.15e-2)" "unprognostic (2.63e-2)" "unprognostic (3.01e-2)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (1.97e-2)" "unprognostic (4.06e-3)" "unprognostic (8.84e-2)" "unprognostic (3.32e-2)" "unprognostic (1.93e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (9.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.58e-1)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" NARS2 "DFNB94, FLJ23441, SLM5" ENSG00000137513 "Asparaginyl-tRNA synthetase 2, mitochondrial" Q96I59 11 78435968-78574874 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Leigh syndrome, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026793 Supported Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Neuronal signaling" "Nucleoplasm, Mitochondria" Cytosol "HPA026793: AB_1848833" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (5.73e-3)" "unprognostic (1.79e-3)" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (5.62e-2)" "unprognostic (4.62e-3)" "prognostic favorable (1.39e-5)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.22e-6)" "unprognostic (8.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" NBAS NAG ENSG00000151779 "NBAS subunit of NRZ tethering complex" A2RRP1 2 15166914-15561334 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 214.7;Inhibitory neurons: 183.6;Oligodendrocyte precursor cells: 152.6;Oligodendrocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036817 Approved Approved "Nuclear membrane,Nucleoli,Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 38: Neurons - Neuronal signaling" "Golgi apparatus" "Nuclear membrane, Nucleoli" "HPA036817: AB_10670925" "unprognostic (1.72e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (3.80e-2)" "unprognostic (4.16e-2)" "unprognostic (1.33e-1)" "unprognostic (1.55e-1)" "unprognostic (1.53e-2)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-1)" "prognostic unfavorable (5.84e-5)" NDUFA1 "CI-MWFE, MWFE" ENSG00000125356 "NADH:ubiquinone oxidoreductase subunit A1" O15239 X 119871832-119876662 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3350.7;Distal tubular cells: 2515.8;Proximal tubular cells: 1899.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029768, HPA054359" Enhanced Approved Mitochondria,Cytosol No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 48: Non-specific - RNA binding" "Cluster 77: Cardiomyocytes - Muscle contraction" Cytosol Mitochondria "HPA029768: AB_2673192, HPA054359: AB_2682461" "unprognostic (1.72e-1)" "unprognostic (3.00e-3)" "unprognostic (3.12e-2)" "unprognostic (1.17e-1)" "unprognostic (1.74e-1)" "unprognostic (7.34e-3)" "unprognostic (1.56e-1)" "unprognostic (8.20e-3)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (8.11e-3)" "unprognostic (4.77e-2)" "prognostic favorable (3.48e-4)" "unprognostic (1.16e-1)" "unprognostic (3.62e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-3)" NDUFA10 CI-42k ENSG00000130414 "NADH:ubiquinone oxidoreductase subunit A10" O95299 2 239892450-240025743 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 332.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 423.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059529, HPA067045, CAB070846" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "CAB070846: AB_11152346, HPA059529: AB_2684051, HPA067045: AB_2732756" "unprognostic (2.12e-2)" "unprognostic (8.94e-3)" "unprognostic (8.73e-2)" "unprognostic (2.02e-2)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (5.71e-2)" "unprognostic (2.47e-2)" "unprognostic (1.05e-1)" "prognostic favorable (2.09e-7)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.98e-1)" "unprognostic (2.95e-1)" NDUFA11 B14.7 ENSG00000174886 "NADH:ubiquinone oxidoreductase subunit A11" Q86Y39 19 5891276-5904006 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1222.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA072209 Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: RS4;11 - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA072209: AB_2686495" "unprognostic (2.24e-1)" "prognostic favorable (4.54e-5)" "unprognostic (8.20e-3)" "prognostic favorable (3.38e-5)" "unprognostic (4.54e-2)" "unprognostic (7.73e-2)" "unprognostic (6.30e-2)" "unprognostic (7.26e-3)" "unprognostic (3.95e-1)" "unprognostic (4.20e-2)" "unprognostic (1.67e-3)" "unprognostic (9.02e-2)" "unprognostic (1.12e-2)" "unprognostic (2.91e-1)" "unprognostic (1.16e-1)" "unprognostic (3.40e-2)" "unprognostic (6.16e-3)" NDUFA12 "B17.2, DAP13" ENSG00000184752 "NADH:ubiquinone oxidoreductase subunit A12" Q9UI09 12 94897055-95003748 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 558.6;tongue: 563.1" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 2532.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039903 Supported Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "HPA039903: AB_10795516" "unprognostic (2.76e-1)" "unprognostic (5.32e-3)" "unprognostic (1.17e-1)" "unprognostic (2.56e-2)" "unprognostic (2.85e-1)" "unprognostic (4.03e-2)" "unprognostic (3.05e-2)" "unprognostic (6.68e-2)" "unprognostic (1.67e-1)" "unprognostic (2.47e-2)" "unprognostic (1.89e-1)" "unprognostic (1.64e-1)" "unprognostic (3.13e-3)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (6.13e-2)" "unprognostic (3.27e-2)" NDUFA13 "B16.6, CDA016, CGI-39, GRIM-19, GRIM19" ENSG00000186010 "NADH:ubiquinone oxidoreductase subunit A13" Q9P0J0 19 19515736-19529054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Electron transport, Host-virus interaction, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1060.0;Late spermatids: 2420.2;Proximal enterocytes: 1128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041213 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 53: Non-specific - mRNA processing" "Cluster 6: Late spermatids - Spermatogenesis" Mitochondria "HPA041213: AB_10794988" "unprognostic (2.87e-1)" "unprognostic (2.88e-3)" "unprognostic (9.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.36e-2)" "unprognostic (5.78e-2)" "unprognostic (6.00e-2)" "unprognostic (3.30e-2)" "unprognostic (2.81e-1)" "unprognostic (1.83e-3)" "unprognostic (1.26e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-2)" "unprognostic (1.33e-1)" "unprognostic (2.37e-1)" "unprognostic (2.15e-2)" "unprognostic (2.15e-2)" NDUFA2 B8 ENSG00000131495 "NADH:ubiquinone oxidoreductase subunit A2" O43678 5 140638740-140647771 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 858.3;Proximal tubular cells: 1081.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035933 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA035933: AB_10669661" "unprognostic (4.48e-1)" "prognostic favorable (6.53e-4)" "unprognostic (3.61e-2)" "unprognostic (1.96e-2)" "unprognostic (6.15e-2)" "unprognostic (5.39e-3)" "unprognostic (4.01e-1)" "unprognostic (2.75e-2)" "unprognostic (1.60e-1)" "unprognostic (4.39e-3)" "unprognostic (1.84e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.78e-2)" "unprognostic (9.96e-2)" "unprognostic (4.22e-1)" "unprognostic (1.30e-3)" NDUFA6 "B14, CI-B14, LYRM6, NADHB14" ENSG00000184983 "NADH:ubiquinone oxidoreductase subunit A6" P56556 22 42085526-42090884 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2477.2;Distal tubular cells: 883.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: Non-specific - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (3.48e-2)" "prognostic favorable (3.87e-4)" "unprognostic (7.00e-3)" "prognostic favorable (4.96e-4)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (4.02e-2)" "unprognostic (2.71e-2)" "unprognostic (1.47e-2)" "unprognostic (8.28e-2)" "unprognostic (3.61e-1)" "prognostic favorable (1.05e-6)" "unprognostic (2.15e-1)" "unprognostic (1.63e-1)" "unprognostic (9.49e-2)" "unprognostic (4.84e-2)" NDUFA9 "CI-39k, COQ11, NDUFS2L, SDR22E1" ENSG00000139180 "NADH:ubiquinone oxidoreductase subunit A9" Q16795 12 4649095-4694317 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 630.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA042268: AB_2677922, HPA073212: AB_2686581" "unprognostic (2.26e-1)" "unprognostic (7.85e-3)" "unprognostic (3.67e-2)" "unprognostic (1.84e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (9.64e-3)" "unprognostic (3.02e-1)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (3.45e-2)" "unprognostic (1.16e-1)" "prognostic favorable (2.57e-7)" "unprognostic (7.80e-2)" "unprognostic (1.71e-1)" "unprognostic (1.93e-2)" "prognostic favorable (5.75e-4)" NDUFAF1 "CGI-65, CIA30" ENSG00000137806 "NADH:ubiquinone oxidoreductase complex assembly factor 1" Q9Y375 15 41387218-41409403 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 94.7;Early spermatids: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039933, HPA040064" Supported Approved Mitochondria,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" "Mitochondria, Cytosol" "HPA039933: AB_10795265, HPA040064: AB_10795687" "unprognostic (2.02e-1)" "unprognostic (1.02e-1)" "unprognostic (1.72e-1)" "unprognostic (2.10e-3)" "unprognostic (2.38e-1)" "unprognostic (1.20e-1)" "prognostic favorable (2.88e-5)" "unprognostic (3.01e-1)" "unprognostic (2.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "prognostic favorable (3.34e-6)" "unprognostic (1.68e-1)" "unprognostic (3.23e-1)" "unprognostic (3.17e-2)" "unprognostic (2.05e-1)" NDUFAF2 "B17.2L, mimitin, MMTN, NDUFA12L" ENSG00000164182 "NADH:ubiquinone oxidoreductase complex assembly factor 2" Q8N183 5 60945177-61154531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "HPA048082, HPA054776" Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 47: Non-specific - Unknown function" "Cluster 57: Non-specific - Translation" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA048082: AB_2680254, HPA054776: AB_2682598" "unprognostic (7.28e-2)" "unprognostic (6.83e-2)" "unprognostic (1.37e-1)" "unprognostic (2.46e-3)" "unprognostic (2.41e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.06e-1)" "unprognostic (4.76e-2)" "unprognostic (8.40e-3)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.79e-2)" "unprognostic (6.10e-2)" "unprognostic (2.37e-1)" "unprognostic (4.66e-2)" NDUFAF3 "2P1, C3orf60, DKFZP564J0123, E3-3, MGC10527" ENSG00000178057 "NADH:ubiquinone oxidoreductase complex assembly factor 3" Q9BU61 3 49020459-49023495 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 329.8" "Cell type enhanced" "Detected in all" "Early spermatids: 1081.6;Late spermatids: 1348.0;Proximal tubular cells: 624.5;Spermatocytes: 799.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035376, HPA035377" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 5: Non-specific - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA035376: AB_2674597, HPA035377: AB_10673219" "unprognostic (2.90e-2)" "unprognostic (2.72e-2)" "unprognostic (6.88e-2)" "unprognostic (3.03e-2)" "unprognostic (3.57e-2)" "unprognostic (2.61e-1)" "unprognostic (6.28e-3)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.64e-2)" "unprognostic (8.62e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.86e-5)" "unprognostic (7.97e-2)" "unprognostic (1.73e-1)" "unprognostic (8.02e-2)" "unprognostic (1.60e-1)" NDUFAF4 "bA22L21.1, C6orf66, HRPAP20, HSPC125, My013" ENSG00000123545 "NADH:ubiquinone oxidoreductase complex assembly factor 4" Q9P032 6 96889315-96897891 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 163.4;Distal tubular cells: 177.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030216, HPA046560" Uncertain Supported Mitochondria,Cytosol NA Yes "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein binding" "Cluster 16: Non-specific - RNA binding" Mitochondria Cytosol "HPA030216: , HPA046560: AB_10966700" "prognostic unfavorable (1.31e-4)" "unprognostic (1.32e-1)" "unprognostic (1.09e-2)" "unprognostic (1.14e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (6.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (2.78e-2)" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" NDUFAF5 "C20orf7, dJ842G6.1" ENSG00000101247 "NADH:ubiquinone oxidoreductase complex assembly factor 5" Q5TEU4 20 13785007-13821580 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Oxidoreductase, Transferase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 20.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 75.1;Early spermatids: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051184 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 18: Non-specific - Mixed function" "HPA051184: AB_2681377" "unprognostic (3.81e-1)" "unprognostic (1.27e-2)" "unprognostic (4.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (8.22e-2)" "unprognostic (1.68e-2)" "unprognostic (3.14e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" "unprognostic (1.74e-3)" "unprognostic (2.41e-2)" "prognostic favorable (2.27e-6)" "unprognostic (5.38e-2)" "unprognostic (5.89e-2)" "unprognostic (6.88e-2)" "unprognostic (1.58e-2)" NDUFAF6 "C8orf38, MGC40214" ENSG00000156170 "NADH:ubiquinone oxidoreductase complex assembly factor 6" Q330K2 8 94895767-95116455 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047148, HPA050545" Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "HPA047148: AB_2679954, HPA050545: AB_2681166" "unprognostic (1.97e-3)" "unprognostic (1.62e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (8.73e-2)" "unprognostic (3.45e-2)" "unprognostic (7.62e-3)" "unprognostic (2.52e-2)" "unprognostic (9.61e-2)" "unprognostic (3.85e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (4.04e-3)" "unprognostic (9.44e-2)" "unprognostic (1.57e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-3)" NDUFAF8 C17orf89 ENSG00000224877 "NADH:ubiquinone oxidoreductase complex assembly factor 8" A1L188 17 81239305-81241310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 264.3" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 369.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA057732 Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA057732: AB_2683513" "unprognostic (4.33e-3)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (4.62e-2)" "unprognostic (1.97e-1)" "unprognostic (9.32e-2)" "unprognostic (3.06e-1)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.71e-2)" "unprognostic (2.40e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.70e-6)" "unprognostic (5.74e-2)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" NDUFB10 PDSW ENSG00000140990 "NADH:ubiquinone oxidoreductase subunit B10" O96000 16 1959538-1961975 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 774.5;skeletal muscle: 1298.5;tongue: 1013.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1788.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073189 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: Non-specific - Transcription" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA073189: AB_2686579" "unprognostic (3.56e-1)" "prognostic favorable (7.38e-4)" "unprognostic (1.08e-1)" "unprognostic (5.22e-2)" "unprognostic (1.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.58e-2)" "unprognostic (1.75e-1)" "unprognostic (7.84e-2)" "unprognostic (1.22e-2)" "unprognostic (2.20e-1)" "unprognostic (1.44e-1)" "prognostic favorable (9.43e-6)" "unprognostic (1.24e-1)" "unprognostic (5.21e-2)" "unprognostic (4.43e-1)" "unprognostic (8.76e-2)" NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142216-47145038 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 717.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030367 Supported Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 48: Non-specific - RNA binding" "Cluster 39: Non-specific - Translation" Mitochondria "HPA030367: AB_10603882" "unprognostic (2.20e-1)" "unprognostic (6.77e-3)" "unprognostic (1.39e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (8.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (3.27e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (8.46e-3)" NDUFB3 B12 ENSG00000119013 "NADH:ubiquinone oxidoreductase subunit B3" O43676 2 201071433-201085750 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 704.3;tongue: 727.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1846.5;Distal tubular cells: 932.9;Proximal tubular cells: 765.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034596 Enhanced NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA034596: AB_10602712" "unprognostic (5.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (7.24e-4)" "unprognostic (1.41e-3)" "unprognostic (6.29e-2)" "unprognostic (8.81e-3)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-2)" "unprognostic (9.40e-3)" "unprognostic (9.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.27e-2)" NDUFB8 "ASHI, CI-ASHI" ENSG00000166136 "NADH:ubiquinone oxidoreductase subunit B8" O95169 10 100523740-100530000 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 908.0;Proximal tubular cells: 902.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "HPA003886, HPA065549" Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA003886: AB_1079463, HPA065549: " "unprognostic (4.07e-2)" "unprognostic (1.95e-3)" "unprognostic (2.28e-1)" "unprognostic (7.33e-2)" "unprognostic (4.88e-2)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (6.46e-2)" "unprognostic (8.33e-2)" "unprognostic (9.09e-2)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-2)" NDUFB9 "B22, LYRM3, UQOR22" ENSG00000147684 "NADH:ubiquinone oxidoreductase subunit B9" Q9Y6M9 8 124539101-124580648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1314.9;tongue: 1486.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1117.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042768 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: NCI-H716 - Unknown function" "Cluster 18: Non-specific - Mixed function" Mitochondria "HPA042768: AB_10797508" "unprognostic (1.18e-2)" "unprognostic (2.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-3)" "unprognostic (8.32e-2)" "unprognostic (9.71e-2)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (3.80e-2)" "unprognostic (1.51e-1)" "unprognostic (3.64e-1)" "prognostic favorable (3.42e-5)" "unprognostic (9.54e-2)" "unprognostic (9.64e-2)" "unprognostic (4.94e-2)" "unprognostic (2.74e-1)" NDUFS1 CI-75k ENSG00000023228 "NADH:ubiquinone oxidoreductase core subunit S1" P28331 2 206114817-206159509 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 181.7;skeletal muscle: 221.6;tongue: 225.2" "Cell type enriched" "Detected in all" 6 "Cardiomyocytes: 845.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064605, CAB070844" Enhanced Supported Mitochondria NA NA 48000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "CAB070844: , HPA064605: AB_2685297" "prognostic unfavorable (3.85e-4)" "unprognostic (1.76e-1)" "unprognostic (9.22e-3)" "unprognostic (5.01e-2)" "unprognostic (8.63e-3)" "unprognostic (3.75e-1)" "unprognostic (3.72e-2)" "unprognostic (6.18e-2)" "unprognostic (2.30e-2)" "unprognostic (3.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.47e-12)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" "unprognostic (4.73e-2)" NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214723 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 464.8;tongue: 633.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055140, HPA061953" Enhanced Supported Mitochondria NA NA 25000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: Non-specific - RNA binding" "Cluster 18: Non-specific - Mixed function" Mitochondria "HPA055140: AB_2682713, HPA061953: AB_2684646" "unprognostic (2.13e-2)" "unprognostic (2.24e-2)" "unprognostic (8.47e-2)" "unprognostic (7.78e-2)" "unprognostic (9.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-2)" "unprognostic (1.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-2)" "unprognostic (3.17e-2)" "unprognostic (1.11e-1)" "prognostic favorable (2.32e-4)" "unprognostic (2.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" NDUFS3 CI-30 ENSG00000213619 "NADH:ubiquinone oxidoreductase core subunit S3" O75489 11 47565336-47584562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 292.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004484, CAB034894" Enhanced Supported "Nuclear bodies,Mitochondria" NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: RS4;11 - Unknown function" "Cluster 18: Non-specific - Mixed function" Mitochondria "Nuclear bodies" "CAB034894: AB_2151118, HPA004484: AB_1079464" "unprognostic (2.18e-1)" "unprognostic (7.42e-3)" "unprognostic (1.75e-1)" "unprognostic (5.01e-2)" "unprognostic (7.51e-2)" "unprognostic (3.13e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "unprognostic (1.93e-1)" "unprognostic (1.41e-2)" "unprognostic (6.75e-3)" "unprognostic (7.73e-2)" "prognostic favorable (2.61e-6)" "unprognostic (2.77e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-2)" "unprognostic (3.17e-3)" NDUFS4 "AQDQ, CI-18" ENSG00000164258 "NADH:ubiquinone oxidoreductase subunit S4" O43181 5 53560633-53683338 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 397.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 475.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003884 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 5: Bronchus - Unknown function" Mitochondria "HPA003884: AB_1079465" "unprognostic (1.25e-1)" "unprognostic (3.61e-3)" "unprognostic (3.44e-2)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" "unprognostic (6.73e-3)" "unprognostic (6.93e-2)" "unprognostic (1.11e-1)" "unprognostic (3.93e-1)" "unprognostic (4.38e-1)" "unprognostic (1.72e-2)" "unprognostic (3.11e-1)" "prognostic favorable (3.85e-6)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" NDUFS6 CI-13kA ENSG00000145494 "NADH:ubiquinone oxidoreductase subunit S6" O75380 5 1801407-1816048 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 615.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 982.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064221 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Enzymes" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA064221: AB_2685217" "unprognostic (2.34e-1)" "unprognostic (1.43e-3)" "unprognostic (4.04e-1)" "unprognostic (9.74e-2)" "unprognostic (5.91e-2)" "unprognostic (6.27e-2)" "unprognostic (1.13e-2)" "unprognostic (5.67e-2)" "unprognostic (3.22e-1)" "unprognostic (9.99e-3)" "unprognostic (1.68e-3)" "unprognostic (8.57e-2)" "unprognostic (2.14e-2)" "unprognostic (1.16e-3)" "unprognostic (2.46e-1)" "unprognostic (9.08e-2)" "unprognostic (1.02e-1)" NDUFS7 "CI-20, FLJ45860, FLJ46880, PSST" ENSG00000115286 "NADH:ubiquinone oxidoreductase core subunit S7" O75251 19 1383527-1395589 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 665.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 730.8;Proximal tubular cells: 765.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 53: Non-specific - mRNA processing" "Cluster 16: Non-specific - RNA binding" "unprognostic (7.36e-2)" "prognostic favorable (2.03e-4)" "unprognostic (5.30e-2)" "unprognostic (3.81e-2)" "unprognostic (1.12e-1)" "unprognostic (5.28e-2)" "unprognostic (2.41e-2)" "unprognostic (5.85e-2)" "unprognostic (4.88e-2)" "unprognostic (2.29e-1)" "unprognostic (1.99e-3)" "unprognostic (8.12e-2)" "prognostic favorable (4.90e-7)" "unprognostic (2.95e-1)" "unprognostic (2.82e-1)" "unprognostic (1.57e-1)" "unprognostic (2.34e-2)" NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 761.9;Late spermatids: 797.2;Proximal tubular cells: 898.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018524, HPA067429" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA018524: AB_1854355, HPA067429: " "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-1)" "unprognostic (7.75e-2)" "unprognostic (3.15e-1)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (3.27e-8)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (9.45e-2)" NDUFV1 CI-51K ENSG00000167792 "NADH:ubiquinone oxidoreductase core subunit V1" P49821 11 67605653-67612554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 526.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 691.6;Proximal tubular cells: 447.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045211, HPA075051" Enhanced Supported Mitochondria,Cytosol No No 37000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "HPA045211: AB_10962830, HPA075051: AB_2686732" "unprognostic (4.57e-2)" "unprognostic (2.17e-2)" "unprognostic (2.84e-1)" "unprognostic (7.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.54e-3)" "unprognostic (1.19e-1)" "unprognostic (3.31e-2)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (4.02e-2)" "unprognostic (3.03e-2)" "prognostic favorable (7.49e-10)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 606.9" "Cell type enhanced" "Detected in all" "Ductal cells: 318.9;Exocrine glandular cells: 343.4;Pancreatic endocrine cells: 324.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003404, HPA077896" Supported Approved Nucleoplasm,Mitochondria,Cytosol No No 7600 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: Myeloma - Humoral immune response" "Cluster 61: Non-specific - Transcription" Mitochondria "Nucleoplasm, Cytosol" "HPA003404: AB_1079466, HPA077896: AB_2686866" "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (2.89e-1)" "unprognostic (8.22e-2)" "unprognostic (1.32e-2)" "unprognostic (6.72e-3)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "unprognostic (6.72e-3)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (1.31e-1)" "unprognostic (6.56e-2)" "unprognostic (1.95e-3)" NFU1 "CGI-33, HIRIP5, NifU, NIFUC" ENSG00000169599 "NFU1 iron-sulfur cluster scaffold" Q9UMS0 2 69396113-69437628 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035826 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 38: Heart - Muscle contraction" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" Cytosol Nucleoplasm "HPA035826: AB_2674803" "unprognostic (4.49e-3)" "unprognostic (5.62e-2)" "unprognostic (5.40e-2)" "unprognostic (1.84e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-3)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-1)" "unprognostic (2.21e-3)" "unprognostic (2.63e-1)" "unprognostic (1.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.87e-1)" NKX6-2 "GTX, NKX6.1, NKX6B" ENSG00000148826 "NK6 homeobox 2" Q9C056 10 132783179-132786147 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding, Repressor" "Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 112.9" "Group enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 70.4;Oligodendrocytes: 114.8" "Cancer enriched" "Detected in some" 5 "glioma: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "white matter: 15.7" "Low region specificity" "Detected in many" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.92e-1)" "unprognostic (4.39e-2)" "unprognostic (2.26e-1)" "unprognostic (2.14e-1)" "unprognostic (1.83e-1)" "unprognostic (1.57e-1)" "unprognostic (1.62e-1)" NSUN3 FLJ22609 ENSG00000178694 "NOP2/Sun RNA methyltransferase 3" Q9H649 3 94062980-94131832 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036181 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 61: Liver - Metabolism" "Cluster 49: Early spermatids - Spermatogenesis" "HPA036181: AB_10602715" "unprognostic (5.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-2)" "unprognostic (6.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.13e-1)" "unprognostic (7.35e-4)" "unprognostic (1.44e-1)" "unprognostic (9.50e-2)" "unprognostic (1.22e-1)" "unprognostic (8.63e-3)" "unprognostic (6.94e-3)" "unprognostic (6.47e-2)" "unprognostic (2.67e-1)" "unprognostic (2.52e-1)" "unprognostic (3.92e-2)" "unprognostic (2.33e-2)" NUBPL "C14orf127, FLJ12660, huInd1, IND1" ENSG00000151413 "Nucleotide binding protein like" Q8TB37 14 31489956-31861224 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 66.1;Inhibitory neurons: 73.1;Oligodendrocyte precursor cells: 84.2;Oligodendrocytes: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029203 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Mitochondria "HPA029203: AB_10602810" "unprognostic (1.49e-1)" "unprognostic (1.71e-2)" "unprognostic (5.21e-3)" "unprognostic (8.28e-2)" "unprognostic (8.25e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "unprognostic (1.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "prognostic favorable (3.64e-8)" "unprognostic (2.82e-2)" "unprognostic (6.60e-2)" "unprognostic (3.67e-3)" "unprognostic (1.56e-2)" OGDH "E1k, KGD1, OGDC-E1, OGDH2" ENSG00000105953 "Oxoglutarate dehydrogenase" Q02218 7 44606572-44709066 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 324.0;skeletal muscle: 363.6;tongue: 374.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019514, HPA020347" Supported Enhanced Mitochondria No No 130000 "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 63: Non-specific - Unknown function" "Cluster 75: Myeloid cells - Innate immune response" Mitochondria "HPA019514: AB_1854772, HPA020347: AB_1854773" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (4.39e-1)" "unprognostic (5.64e-3)" "unprognostic (3.02e-3)" "unprognostic (1.20e-1)" "unprognostic (3.45e-1)" "unprognostic (7.58e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.30e-2)" "prognostic favorable (2.22e-14)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (2.23e-2)" "unprognostic (5.88e-3)" OPA1 "FLJ12460, KIAA0567, MGM1, NPG, NTG" ENSG00000198836 "OPA1 mitochondrial dynamin like GTPase" O60313 3 193593144-193697811 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Sensory transduction, Vision" Hydrolase "Cardiomyopathy, Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 219.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036926, HPA036927" Supported Supported Nucleoplasm,Mitochondria NA NA 10000 "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondria" "Cluster 77: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Mitochondria" "HPA036926: AB_10671247, HPA036927: AB_2675388" "unprognostic (2.10e-2)" "unprognostic (9.23e-3)" "unprognostic (7.98e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (1.62e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (3.48e-2)" "prognostic favorable (1.84e-4)" "unprognostic (2.92e-1)" "unprognostic (4.75e-1)" "unprognostic (4.50e-3)" "unprognostic (3.21e-1)" PET100 C19orf79 ENSG00000229833 "PET100 cytochrome c oxidase chaperone" P0DJ07 19 7629793-7631956 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067288 Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 53: Non-specific - mRNA processing" "Cluster 74: Pancreatic cells - Mixed function" Mitochondria "HPA067288: AB_2732762" "unprognostic (7.02e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.57e-1)" "unprognostic (9.87e-3)" "unprognostic (2.14e-1)" "unprognostic (4.18e-2)" "unprognostic (1.70e-1)" "prognostic favorable (7.97e-4)" "unprognostic (4.89e-1)" "unprognostic (2.88e-3)" "unprognostic (2.49e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (2.66e-2)" "prognostic favorable (2.44e-4)" PMPCB "MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing subunit beta" O75439 7 103297435-103329511 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria No No 19000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 31: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" Mitochondria "HPA040674: AB_10961998, HPA074168: AB_2686671" "prognostic favorable (2.79e-4)" "unprognostic (3.11e-1)" "unprognostic (7.18e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "unprognostic (7.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-3)" "prognostic favorable (2.95e-8)" "unprognostic (2.59e-2)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" PNPLA8 "IPLA2-2, IPLA2G, iPLA2gamma" ENSG00000135241 "Patatin like phospholipase domain containing 8" Q9NP80 7 108470417-108569666 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020083 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 31: Non-specific - Transcription" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA020083: AB_1851849" "unprognostic (4.48e-2)" "unprognostic (3.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (4.61e-1)" "unprognostic (2.73e-2)" "unprognostic (3.48e-2)" "unprognostic (3.32e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (2.49e-1)" "prognostic favorable (1.86e-6)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (4.28e-3)" "unprognostic (1.24e-1)" PNPT1 "DFNB70, old-35, OLD35, PNPase" ENSG00000138035 "Polyribonucleotide nucleotidyltransferase 1" Q8TCS8 2 55634061-55693863 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transport" "Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, RNA-binding, Transferase" "Deafness, Disease variant, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033424, HPA034602, HPA034603" Supported Supported Mitochondria,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 69: BICR 18 - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria Cytosol "CAB033424: AB_2299801, HPA034602: AB_2674243, HPA034603: AB_10603130" "unprognostic (9.09e-2)" "unprognostic (7.40e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (3.40e-2)" "unprognostic (1.03e-2)" "prognostic unfavorable (1.95e-7)" "unprognostic (1.88e-1)" "unprognostic (5.93e-3)" "unprognostic (5.23e-2)" "prognostic unfavorable (5.44e-5)" "unprognostic (2.19e-2)" "unprognostic (2.11e-2)" "unprognostic (6.92e-2)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (1.21e-1)" POLG "POLG1, POLGA" ENSG00000140521 "DNA polymerase gamma, catalytic subunit" P54098 15 89305198-89334861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 70.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056821, HPA078482" Approved Supported Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Mitochondria "HPA056821: AB_2683247, HPA078482: " "unprognostic (1.87e-1)" "unprognostic (4.71e-2)" "unprognostic (2.61e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (3.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.63e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.65e-3)" "unprognostic (1.58e-2)" "unprognostic (4.29e-2)" "unprognostic (2.07e-1)" "unprognostic (3.45e-1)" POLG2 "HP55, MTPOLB" ENSG00000256525 "DNA polymerase gamma 2, accessory subunit" Q9UHN1 17 64477785-64497054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB017030, HPA023202, HPA078396" Approved Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 65: Breast cancer - Unknown function" "Cluster 11: Non-specific - Transcription" Mitochondria "Nuclear bodies" "CAB017030: , HPA023202: AB_1855523, HPA078396: " "unprognostic (1.76e-1)" "unprognostic (2.20e-1)" "unprognostic (1.59e-1)" "unprognostic (7.02e-2)" "unprognostic (6.01e-2)" "unprognostic (2.91e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (4.38e-2)" "unprognostic (8.46e-2)" "unprognostic (3.14e-1)" "unprognostic (5.17e-3)" "prognostic unfavorable (6.59e-4)" "prognostic unfavorable (1.17e-5)" "unprognostic (5.17e-2)" "unprognostic (1.58e-1)" "unprognostic (2.88e-2)" "unprognostic (4.82e-2)" PUS1 ENSG00000177192 "Pseudouridine synthase 1" Q9Y606 12 131929200-131945896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing, tRNA processing" Isomerase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051636, HPA057593" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Mitochondria" "HPA051636: AB_2681560, HPA057593: AB_2683479" "unprognostic (2.72e-1)" "unprognostic (9.13e-2)" "unprognostic (1.81e-1)" "unprognostic (2.69e-2)" "unprognostic (8.12e-3)" "unprognostic (8.07e-2)" "unprognostic (4.57e-3)" "unprognostic (7.34e-2)" "unprognostic (1.01e-1)" "unprognostic (3.34e-1)" "unprognostic (2.06e-1)" "unprognostic (5.30e-2)" "prognostic unfavorable (3.49e-8)" "unprognostic (1.80e-3)" "unprognostic (8.06e-2)" "unprognostic (8.59e-2)" "unprognostic (1.56e-2)" QRSL1 "DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA" ENSG00000130348 "Glutaminyl-tRNA amidotransferase subunit QRSL1" Q9H0R6 6 106629578-106668417 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "memory B-cell: 86.4;naive B-cell: 71.0" "Lineage enriched" "Detected in all" 7 "B-cells: 86.4" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029585, HPA029587" Approved Approved Vesicles,Centrosome NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" Vesicles Centrosome "HPA029585: AB_10599823, HPA029587: AB_10602311" "unprognostic (1.86e-3)" "unprognostic (5.58e-2)" "unprognostic (6.19e-3)" "unprognostic (3.45e-1)" "unprognostic (2.11e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (8.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (4.03e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.83e-4)" "unprognostic (2.06e-1)" "unprognostic (2.09e-1)" "unprognostic (2.04e-1)" "unprognostic (3.46e-1)" RINT1 "FLJ11785, RINT-1" ENSG00000135249 "RAD50 interactor 1" Q6NUQ1 7 105532169-105567677 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019875, HPA031646" Approved Approved "Golgi apparatus" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Golgi apparatus" "HPA019875: AB_1856283, HPA031646: AB_2673975" "unprognostic (1.58e-2)" "unprognostic (3.94e-2)" "unprognostic (9.00e-2)" "unprognostic (1.80e-1)" "unprognostic (2.50e-1)" "unprognostic (7.95e-2)" "unprognostic (4.68e-3)" "unprognostic (1.33e-2)" "unprognostic (4.96e-3)" "unprognostic (2.41e-1)" "unprognostic (8.72e-2)" "unprognostic (5.35e-2)" "unprognostic (8.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.39e-5)" "unprognostic (1.76e-1)" RMND1 "bA351K16.3, C6orf96, FLJ20627, RMD1" ENSG00000155906 "Required for meiotic nuclear division 1 homolog" Q9NWS8 6 151404762-151452158 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031397, HPA031398, HPA031399" Approved Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: Non-specific - Protein binding" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA031397: AB_2673861, HPA031398: AB_2673862, HPA031399: AB_10601156" "unprognostic (1.12e-1)" "unprognostic (4.45e-2)" "unprognostic (9.70e-3)" "unprognostic (6.67e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.50e-3)" "unprognostic (6.56e-2)" "unprognostic (1.02e-1)" "unprognostic (1.73e-1)" "unprognostic (2.03e-1)" "unprognostic (3.57e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (9.74e-2)" "unprognostic (1.04e-1)" RNASEH1 ENSG00000171865 "Ribonuclease H1" O60930 2 3541430-3558333 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "HPA034817, HPA043037" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 74: Pancreatic cells - Mixed function" "Nucleoplasm, Cytosol" "HPA034817: , HPA043037: AB_2678280" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (8.81e-3)" "unprognostic (4.32e-3)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (9.43e-2)" "unprognostic (8.46e-3)" "unprognostic (6.38e-2)" "unprognostic (2.29e-3)" "unprognostic (2.67e-1)" "unprognostic (4.06e-2)" "unprognostic (2.34e-2)" "unprognostic (2.11e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-3)" RRM2B p53R2 ENSG00000048392 "Ribonucleotide reductase regulatory TP53 inducible subunit M2B" Q7LG56 8 102204502-102238961 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Deoxyribonucleotide synthesis, DNA damage, DNA repair" Oxidoreductase "Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006854, HPA028812" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "Nucleoplasm, Cytosol" "CAB006854: , HPA028812: AB_10602246" "unprognostic (7.76e-3)" "unprognostic (4.14e-2)" "unprognostic (9.41e-3)" "unprognostic (3.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.28e-1)" "unprognostic (5.51e-2)" "unprognostic (1.35e-2)" "unprognostic (1.66e-1)" "unprognostic (9.40e-2)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-2)" "unprognostic (4.32e-1)" "unprognostic (1.47e-1)" "unprognostic (2.52e-1)" "unprognostic (7.17e-2)" SACS "ARSACS, DKFZp686B15167, DNAJC29, KIAA0730, PPP1R138, SPAX6" ENSG00000151835 "Sacsin molecular chaperone" Q9NZJ4 13 23328826-23433740 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 68.3;Excitatory neurons: 85.0;Inhibitory neurons: 106.0;Mucus glandular cells: 62.6;Oligodendrocyte precursor cells: 73.2;Oligodendrocytes: 104.8;Skeletal myocytes: 84.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017714 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 15: Smooth muscle cells - Muscle contraction" "CAB017714: " "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.02e-3)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.26e-2)" "unprognostic (1.66e-1)" "unprognostic (2.05e-3)" "unprognostic (2.59e-2)" "unprognostic (2.49e-1)" "unprognostic (4.14e-2)" "unprognostic (5.05e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.21e-6)" "unprognostic (2.84e-1)" "unprognostic (4.06e-2)" "unprognostic (3.67e-2)" "unprognostic (7.65e-4)" SARS2 "FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS" ENSG00000104835 "Seryl-tRNA synthetase 2, mitochondrial" Q9NP81 19 38915266-38930763 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 37.8;Late spermatids: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "HPA052730, HPA056957" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria" Vesicles "HPA052730: AB_2681929, HPA056957: AB_2683286" "unprognostic (3.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.88e-3)" "unprognostic (4.38e-3)" "unprognostic (1.22e-1)" "unprognostic (2.57e-2)" "unprognostic (8.62e-3)" "unprognostic (8.36e-2)" "unprognostic (1.67e-1)" "unprognostic (5.62e-3)" "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.69e-2)" SCO1 SCOD1 ENSG00000133028 "Synthesis of cytochrome C oxidase 1" O75880 17 10672474-10698375 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021565, HPA021579" Enhanced NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 49: Non-specific - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA021565: AB_1856631, HPA021579: AB_1856632" "unprognostic (6.11e-3)" "unprognostic (2.88e-1)" "unprognostic (5.12e-3)" "unprognostic (1.09e-2)" "unprognostic (1.92e-2)" "unprognostic (7.52e-2)" "unprognostic (5.01e-2)" "unprognostic (3.02e-2)" "unprognostic (7.09e-3)" "unprognostic (1.83e-2)" "unprognostic (2.43e-3)" "unprognostic (3.84e-2)" "prognostic favorable (9.69e-7)" "unprognostic (4.94e-3)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.12e-2)" SCO2 "MYP6, SCO1L" ENSG00000284194 "Synthesis of cytochrome C oxidase 2" O43819 22 50523568-50526461 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Cardiomyopathy, Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046943, HPA056254" Uncertain Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" Mitochondria "HPA046943: AB_2732536, HPA056254: AB_2683080" SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218241-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 601.0;skeletal muscle: 479.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 459.4;Proximal enterocytes: 261.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "CAB034929, HPA041981, HPA064582" Enhanced Supported Nucleoli,Mitochondria No No 360000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Enzymes" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293" "prognostic unfavorable (6.00e-4)" "unprognostic (1.93e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "prognostic favorable (9.53e-8)" "unprognostic (1.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (1.79e-1)" SDHAF1 LYRM8 ENSG00000205138 "Succinate dehydrogenase complex assembly factor 1" A6NFY7 19 35995188-35996312 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064277, HPA074563" Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 70: Basal prostatic cells - Lipid metabolism" Mitochondria "HPA064277: AB_2685231, HPA074563: " "unprognostic (2.01e-1)" "unprognostic (3.46e-2)" "unprognostic (2.22e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-1)" "unprognostic (4.47e-2)" "unprognostic (5.25e-2)" "unprognostic (2.29e-2)" "unprognostic (1.24e-1)" "unprognostic (3.78e-2)" "unprognostic (6.89e-3)" "unprognostic (1.83e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.38e-2)" "unprognostic (2.59e-1)" "unprognostic (2.24e-1)" "unprognostic (3.59e-2)" SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 391.6;Distal tubular cells: 429.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA045727 Approved "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" SERPINC1 "AT3, ATIII, MGC22579" ENSG00000117601 "Serpin family C member 1" P01008 1 173903800-173917327 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1341 "liver: 5056.6" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 2568.1" "Cancer enriched" "Detected in some" 871 "liver cancer: 1504.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gastric cancer: 2.5;liver cancer: 7.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001816, CAB016790, HPA024007" Supported "Secreted to blood" NA NA 120000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "CAB016790: , HPA001816: AB_1079926, HPA024007: AB_1856732" "unprognostic (1.28e-2)" "unprognostic (2.22e-1)" "unprognostic (3.83e-2)" "unprognostic (5.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.93e-2)" "prognostic favorable (3.40e-5)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (3.48e-2)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.36e-2)" "unprognostic (5.28e-3)" "unprognostic (5.80e-2)" "unprognostic (6.35e-2)" "unprognostic (8.21e-2)" SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Mitochondria" Vesicles "HPA018028: AB_1856792, HPA020872: AB_1856793" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (3.61e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (9.49e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (6.84e-2)" "unprognostic (4.56e-2)" "unprognostic (8.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.70e-3)" "unprognostic (4.22e-3)" "unprognostic (1.43e-1)" "unprognostic (6.21e-3)" "unprognostic (3.07e-3)" SLC25A10 DIC ENSG00000183048 "Solute carrier family 25 member 10" Q9UBX3 17 81712236-81721016 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Lipid transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 183.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.4;Late spermatids: 77.5;Proximal enterocytes: 54.1;Proximal tubular cells: 68.1;Undifferentiated cells: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" HPA023048 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria Nucleoplasm "HPA023048: AB_2301950" "unprognostic (7.17e-2)" "unprognostic (2.38e-2)" "unprognostic (2.36e-2)" "unprognostic (1.36e-1)" "unprognostic (9.50e-2)" "prognostic favorable (2.56e-4)" "unprognostic (5.66e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-2)" "prognostic favorable (8.14e-4)" "unprognostic (6.73e-2)" "unprognostic (1.33e-1)" "unprognostic (6.02e-2)" "unprognostic (6.32e-2)" "unprognostic (2.76e-1)" "unprognostic (2.05e-1)" "prognostic favorable (1.31e-4)" SLC25A12 Aralar ENSG00000115840 "Solute carrier family 25 member 12" O75746 2 171783405-171999859 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 97.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 123.9;Excitatory neurons: 146.3;Inhibitory neurons: 171.3;Oligodendrocyte precursor cells: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035333, HPA035334" Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA 9100 "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 45: Non-specific - Cell proliferation" "Cluster 37: Neurons - Neuronal signaling" "Nuclear speckles" Cytosol "HPA035333: AB_10603028, HPA035334: AB_2674577" "unprognostic (3.24e-2)" "unprognostic (2.52e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (2.65e-2)" "unprognostic (7.27e-2)" "unprognostic (4.21e-3)" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (4.96e-2)" "unprognostic (7.76e-2)" "unprognostic (1.13e-1)" "prognostic favorable (2.91e-8)" "unprognostic (8.64e-3)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" SLC25A21 "ODC, ODC1" ENSG00000183032 "Solute carrier family 25 member 21" Q9BQT8 14 36677921-37172606 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Antiport, Lipid transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 41.4;Excitatory neurons: 13.9;Inhibitory neurons: 10.1;Oligodendrocyte precursor cells: 11.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 12.5" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000662 Uncertain NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "HPA000662: AB_1080000" "unprognostic (6.81e-3)" "unprognostic (6.98e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-1)" "unprognostic (2.78e-2)" "unprognostic (2.20e-1)" "unprognostic (2.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.32e-2)" "unprognostic (6.86e-2)" "unprognostic (9.16e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-4)" "unprognostic (9.09e-3)" "unprognostic (1.95e-2)" "unprognostic (3.52e-1)" "unprognostic (1.07e-1)" SLC25A26 ENSG00000144741 "Solute carrier family 25 member 26" Q70HW3 3 66133610-66388116 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 129.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026887 Supported Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 5: Non-specific - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA026887: AB_2189921" "unprognostic (1.93e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-2)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (7.83e-2)" "unprognostic (7.94e-2)" "unprognostic (5.38e-2)" "unprognostic (1.53e-1)" "unprognostic (3.54e-1)" "unprognostic (9.21e-2)" "unprognostic (8.43e-2)" "prognostic favorable (1.73e-5)" "unprognostic (4.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.33e-1)" "unprognostic (2.07e-1)" SLC25A3 PHC ENSG00000075415 "Solute carrier family 25 member 3" Q00325 12 98593591-98606379 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1537.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1730.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045709 Supported Mitochondria NA NA 83000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Mixed function" Mitochondria "HPA045709: AB_10965843" "unprognostic (1.16e-2)" "unprognostic (4.68e-1)" "unprognostic (1.95e-2)" "unprognostic (1.52e-1)" "unprognostic (1.56e-2)" "unprognostic (6.38e-2)" "unprognostic (3.25e-3)" "unprognostic (9.41e-2)" "unprognostic (4.98e-2)" "unprognostic (6.43e-2)" "unprognostic (5.65e-2)" "unprognostic (7.40e-2)" "prognostic favorable (8.11e-7)" "unprognostic (3.45e-1)" "unprognostic (2.99e-1)" "unprognostic (8.66e-3)" "unprognostic (4.72e-2)" SLC25A4 "ANT1, PEO2, PEO3, T1" ENSG00000151729 "Solute carrier family 25 member 4" P12235 4 185143266-185150382 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Host-virus interaction, Transport" "Cardiomyopathy, Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 245.1;skeletal muscle: 190.8;tongue: 346.6" "Cell type enriched" "Detected in all" 6 "Cardiomyocytes: 6458.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 380000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (4.19e-2)" "unprognostic (1.06e-2)" "unprognostic (3.11e-1)" "unprognostic (8.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-3)" "unprognostic (8.25e-2)" "unprognostic (1.26e-2)" "unprognostic (7.87e-2)" "unprognostic (1.60e-1)" "prognostic favorable (3.41e-4)" "unprognostic (2.05e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (8.28e-3)" SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 232.2;tongue: 271.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 207.4;Early spermatids: 225.4;Late spermatids: 315.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: Non-specific - Nuclear processes" "Cluster 51: Late spermatids - Spermatogenesis" Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 780.5;Proximal enterocytes: 654.0;Proximal tubular cells: 3029.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Enzymes" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" SURF1 ENSG00000148290 "SURF1 cytochrome c oxidase assembly factor" Q15526 9 133351758-133356676 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033946 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 55: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" "CAB033946: AB_2302648" "unprognostic (1.87e-1)" "unprognostic (7.76e-3)" "unprognostic (1.34e-2)" "unprognostic (4.26e-3)" "unprognostic (3.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.35e-1)" "unprognostic (7.68e-2)" "unprognostic (3.00e-1)" "unprognostic (4.75e-2)" "unprognostic (1.11e-2)" "unprognostic (2.66e-1)" "prognostic favorable (6.92e-9)" "unprognostic (3.91e-2)" "unprognostic (2.13e-1)" "unprognostic (4.58e-2)" "unprognostic (1.98e-1)" TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 102.9;Proximal enterocytes: 86.1;Proximal tubular cells: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA021626: AB_1846148, HPA021643: AB_1846149, HPA024294: AB_1846150" "unprognostic (1.26e-1)" "unprognostic (2.92e-2)" "unprognostic (4.55e-3)" "unprognostic (9.82e-2)" "unprognostic (1.30e-1)" "unprognostic (9.30e-3)" "unprognostic (2.83e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (5.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" TARS2 "FLJ12528, TARSL1" ENSG00000143374 "Threonyl-tRNA synthetase 2, mitochondrial" Q9BW92 1 150487364-150507609 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028626 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: Non-specific - RNA binding" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Cytosol" "HPA028626: AB_10601719" "unprognostic (2.48e-1)" "unprognostic (7.75e-2)" "unprognostic (6.68e-2)" "unprognostic (3.75e-3)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "unprognostic (4.93e-2)" "unprognostic (2.14e-1)" "unprognostic (9.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.25e-1)" "unprognostic (3.76e-2)" "unprognostic (9.23e-2)" "unprognostic (9.29e-3)" "unprognostic (4.19e-2)" "unprognostic (1.14e-2)" "unprognostic (5.55e-2)" TFAM "TCF6, TCF6L2" ENSG00000108064 "Transcription factor A, mitochondrial" Q00059 10 58385345-58399220 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 320.4;Late spermatids: 1067.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040648, HPA063684" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 36: Spermatids - Spermatogenesis" Mitochondria "HPA040648: AB_10795635, HPA063684: AB_2685089" "unprognostic (5.30e-2)" "unprognostic (1.14e-1)" "unprognostic (6.34e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.10e-2)" "unprognostic (3.40e-2)" "unprognostic (1.54e-2)" "unprognostic (3.23e-2)" "unprognostic (1.24e-2)" "prognostic favorable (2.74e-4)" "unprognostic (1.99e-2)" "unprognostic (5.39e-2)" "prognostic favorable (2.22e-5)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (6.76e-2)" TIMM22 "TEX4, TIM22" ENSG00000177370 "Translocase of inner mitochondrial membrane 22" Q9Y584 17 997129-1003671 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "basophil: 4.0" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.0" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045138 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "HPA045138: AB_10962055" "unprognostic (2.69e-1)" "unprognostic (3.42e-1)" "unprognostic (2.57e-1)" "unprognostic (8.69e-3)" "unprognostic (3.00e-2)" "unprognostic (2.75e-2)" "unprognostic (2.16e-2)" "unprognostic (9.36e-2)" "unprognostic (2.37e-1)" "unprognostic (1.80e-1)" "prognostic favorable (3.42e-4)" "unprognostic (1.27e-1)" "prognostic favorable (1.41e-4)" "unprognostic (2.45e-1)" "unprognostic (3.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.70e-3)" TIMM8A "DDP, DFN1, MTS" ENSG00000126953 "Translocase of inner mitochondrial membrane 8A" O60220 X 101345661-101348742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Deafness, Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 63.3;Hepatocytes: 78.4;Suprabasal keratinocytes: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003628 Supported Supported Mitochondria NA NA 59000 "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 62: Granulocytes - Innate immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Mitochondria "HPA003628: AB_1080284" "prognostic unfavorable (7.89e-5)" "unprognostic (1.36e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (8.87e-5)" "unprognostic (2.06e-1)" "unprognostic (9.28e-3)" "unprognostic (5.14e-3)" "unprognostic (8.32e-2)" "unprognostic (1.90e-2)" "unprognostic (1.86e-3)" "unprognostic (6.41e-2)" "unprognostic (8.57e-3)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (7.75e-2)" "unprognostic (1.70e-1)" "unprognostic (3.86e-2)" TIMMDC1 "C3orf1, FLJ22597" ENSG00000113845 "Translocase of inner mitochondrial membrane domain containing 1" Q9NPL8 3 119498547-119525090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053214, HPA055846" Uncertain Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondria" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA053214: AB_2682081, HPA055846: AB_2682941" "unprognostic (3.95e-2)" "unprognostic (8.85e-2)" "unprognostic (1.73e-1)" "unprognostic (2.53e-2)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (9.60e-2)" "unprognostic (6.25e-2)" "unprognostic (3.39e-1)" "unprognostic (4.67e-3)" "unprognostic (1.05e-1)" "unprognostic (3.87e-2)" "unprognostic (8.89e-2)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-1)" TK2 SCA31 ENSG00000166548 "Thymidine kinase 2" O00142 16 66508003-66552544 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041162 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 36: Non-specific - Unknown function" "Cluster 69: Macrophages - Innate immune response" "HPA041162: AB_10961178" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.27e-3)" "unprognostic (3.94e-1)" "unprognostic (2.93e-1)" "unprognostic (1.10e-1)" "unprognostic (4.83e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-1)" "unprognostic (3.59e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.18e-6)" "unprognostic (3.05e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (7.05e-2)" TMEM126B HT007 ENSG00000171204 "Transmembrane protein 126B" Q8IUX1 11 85628573-85636539 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014480, HPA019186" Uncertain Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA014480: AB_1858083, HPA019186: AB_1858084" "unprognostic (1.11e-1)" "unprognostic (4.97e-2)" "unprognostic (1.10e-1)" "unprognostic (2.79e-2)" "unprognostic (5.67e-1)" "unprognostic (1.44e-1)" "unprognostic (5.55e-3)" "unprognostic (1.22e-1)" "unprognostic (1.45e-2)" "unprognostic (6.70e-3)" "unprognostic (4.42e-2)" "unprognostic (4.30e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (6.50e-2)" "unprognostic (5.86e-2)" "unprognostic (2.66e-2)" TMEM70 FLJ20533 ENSG00000175606 "Transmembrane protein 70" Q9BUB7 8 73972437-73982783 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 100.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023187, CAB034226" Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 66: Endothelial cells - Angiogenesis" Mitochondria Nucleoplasm "CAB034226: AB_2205189, HPA023187: AB_2671101" "unprognostic (2.26e-3)" "unprognostic (4.87e-1)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (8.22e-3)" "unprognostic (9.17e-2)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (7.04e-2)" "unprognostic (2.88e-2)" "unprognostic (9.14e-2)" "unprognostic (3.65e-3)" "unprognostic (6.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.13e-1)" "unprognostic (2.70e-2)" TRIT1 "FLJ20061, IPT" ENSG00000043514 "TRNA isopentenyltransferase 1" Q9H3H1 1 39838110-39883511 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024174, HPA027330" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 54: Extravillous trophoblasts - Unknown function" Mitochondria "HPA024174: AB_1858346, HPA027330: " "unprognostic (4.61e-2)" "unprognostic (1.77e-1)" "unprognostic (8.38e-3)" "prognostic unfavorable (8.80e-4)" "unprognostic (4.00e-2)" "unprognostic (8.55e-2)" "prognostic unfavorable (5.34e-6)" "unprognostic (2.90e-1)" "unprognostic (2.21e-3)" "unprognostic (3.18e-2)" "unprognostic (3.54e-1)" "unprognostic (6.68e-3)" "prognostic unfavorable (7.08e-8)" "unprognostic (6.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (6.90e-2)" TRMT10C "FLJ20432, MRPP1, RG9MTD1" ENSG00000174173 "TRNA methyltransferase 10C, mitochondrial RNase P subunit" Q7L0Y3 3 101561868-101566446 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036671 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondria" "Cluster 16: Non-specific - RNA binding" Mitochondria Nucleoplasm "HPA036671: AB_10602085" "unprognostic (7.42e-2)" "unprognostic (2.68e-1)" "unprognostic (9.08e-3)" "unprognostic (4.47e-3)" "unprognostic (5.01e-2)" "unprognostic (5.55e-2)" "prognostic unfavorable (6.56e-5)" "unprognostic (1.67e-2)" "unprognostic (8.48e-2)" "unprognostic (5.42e-2)" "unprognostic (4.70e-2)" "unprognostic (3.28e-2)" "prognostic favorable (3.32e-5)" "unprognostic (2.77e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" TRMT5 "KIAA1393, TRM5" ENSG00000126814 "TRNA methyltransferase 5" Q32P41 14 60971441-60981170 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 234.7;Late spermatids: 69.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000943 Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 46: Non-specific - Unknown function" "Cluster 49: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA000943: AB_1080388" "unprognostic (1.58e-2)" "unprognostic (3.62e-2)" "unprognostic (6.63e-3)" "unprognostic (1.11e-2)" "unprognostic (7.70e-3)" "unprognostic (2.26e-2)" "unprognostic (7.82e-3)" "unprognostic (4.50e-2)" "unprognostic (3.95e-1)" "unprognostic (1.78e-1)" "unprognostic (1.47e-1)" "unprognostic (2.84e-2)" "unprognostic (1.60e-3)" "unprognostic (1.82e-1)" "unprognostic (1.97e-2)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" TRMU "FLJ10140, MTO2, MTU1, TRMT" ENSG00000100416 "TRNA mitochondrial 2-thiouridylase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA000824: AB_2732393, HPA035273: AB_10602901, HPA043300: AB_2678415" "unprognostic (2.96e-1)" "unprognostic (1.09e-2)" "unprognostic (8.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.64e-1)" "unprognostic (3.52e-3)" "prognostic unfavorable (3.04e-5)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (7.89e-2)" "prognostic favorable (6.86e-4)" "unprognostic (4.74e-3)" "prognostic unfavorable (5.63e-6)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (7.44e-3)" TSFM "EF-TS, EF-Tsmt" ENSG00000123297 "Ts translation elongation factor, mitochondrial" P43897 12 57782761-57808071 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 29.0;Erythroid cells: 12.1;Late spermatids: 34.0;Plasma cells: 12.7;Squamous epithelial cells: 15.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006204 Supported Nucleoplasm,Mitochondria NA NA 9200 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 61: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA006204: AB_1080405" "unprognostic (1.17e-1)" "unprognostic (6.84e-3)" "unprognostic (1.93e-2)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (2.56e-3)" "unprognostic (2.49e-2)" "unprognostic (1.53e-1)" "unprognostic (8.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.49e-1)" "unprognostic (1.49e-3)" "prognostic favorable (8.82e-4)" "unprognostic (3.05e-1)" "unprognostic (6.97e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" TTC19 "FLJ20343, MGC19520" ENSG00000011295 "Tetratricopeptide repeat domain 19" Q6DKK2 17 15999784-16045015 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023010, HPA052380" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 49: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" Mitochondria "HPA023010: AB_1858429, HPA052380: AB_2681806" "unprognostic (1.04e-2)" "unprognostic (4.90e-3)" "unprognostic (2.87e-2)" "unprognostic (4.80e-3)" "unprognostic (8.09e-2)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.84e-2)" "unprognostic (8.34e-2)" "unprognostic (1.72e-2)" "unprognostic (2.30e-3)" "unprognostic (5.14e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.31e-1)" "unprognostic (3.22e-1)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846348 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria NA NA 610000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: Non-specific - Transcription" "Cluster 16: Non-specific - RNA binding" Mitochondria "CAB075730: AB_2665736, CAB075731: AB_2665737, CAB075732: AB_2665738, HPA018991: AB_1858458, HPA024087: AB_1858459" "unprognostic (1.40e-1)" "unprognostic (7.56e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.55e-2)" "unprognostic (3.39e-1)" "unprognostic (1.23e-3)" "unprognostic (8.05e-2)" "unprognostic (8.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "prognostic favorable (2.69e-6)" "unprognostic (5.26e-2)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (7.36e-2)" TWNK "C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL" ENSG00000107815 "Twinkle mtDNA helicase" Q96RR1 10 100987367-100994403 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "Helicase, Hydrolase" "Deafness, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002532 Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 16: Non-specific - RNA binding" "HPA002532: AB_1078311" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "unprognostic (1.16e-1)" "unprognostic (2.19e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (7.82e-3)" "unprognostic (7.99e-2)" "unprognostic (1.22e-1)" "unprognostic (7.95e-2)" "unprognostic (7.52e-2)" "unprognostic (1.96e-2)" "unprognostic (9.46e-2)" "unprognostic (9.82e-3)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 84000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 54: Extravillous trophoblasts - Unknown function" Mitochondria "CAB008681: AB_1623682, HPA000994: AB_1080267" "unprognostic (5.11e-2)" "unprognostic (4.40e-3)" "unprognostic (4.40e-3)" "unprognostic (1.07e-2)" "unprognostic (5.85e-2)" "unprognostic (4.28e-2)" "unprognostic (4.02e-2)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "prognostic favorable (2.04e-4)" "prognostic favorable (1.17e-6)" "unprognostic (1.49e-2)" "unprognostic (2.78e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" TYMP "ECGF1, MNGIE" ENSG00000025708 "Thymidine phosphorylase" P19971 22 50525752-50530032 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Glycosyltransferase, Growth factor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 676.8;Langerhans cells: 459.1;Macrophages: 533.9;monocytes: 947.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 135.8;eosinophil: 74.9;intermediate monocyte: 98.4;myeloid DC: 39.5;neutrophil: 114.1;non-classical monocyte: 77.1" "Group enriched" "Detected in all" 10 "dendritic cells: 39.5;granulocytes: 114.1;monocytes: 135.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 106.8" "Not detected" "Not detected" "HPA000530, HPA001072, CAB002518" Enhanced Approved "Nuclear bodies,Golgi apparatus,Cytosol" NA NA 11000000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 23: Langerhans cells - Immune response" "Nuclear bodies, Golgi apparatus" Cytosol "CAB002518: AB_563953, HPA000530: AB_2666017, HPA001072: AB_1080274" "unprognostic (7.02e-3)" "unprognostic (1.00e-1)" "unprognostic (3.61e-1)" "prognostic favorable (4.34e-5)" "unprognostic (7.60e-2)" "unprognostic (1.16e-2)" "unprognostic (2.40e-1)" "unprognostic (7.17e-2)" "unprognostic (4.64e-2)" "unprognostic (1.33e-1)" "unprognostic (3.31e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (3.50e-8)" "unprognostic (1.32e-1)" "unprognostic (4.02e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" UQCC2 "bA6B20.2, C6orf125, Cbp6, M19, MGC14833, MNF1" ENSG00000137288 "Ubiquinol-cytochrome c reductase complex assembly factor 2" Q9BRT2 6 33694293-33711727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1219.6;Late spermatids: 1159.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA039111 Uncertain Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 38: Heart - Muscle contraction" "Cluster 15: Non-specific - Protein binding" "Cluster 18: Non-specific - Mixed function" Mitochondria "Nuclear bodies" "HPA039111: AB_2676352" "unprognostic (3.58e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (1.93e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.21e-2)" "unprognostic (1.50e-1)" "unprognostic (2.35e-3)" "unprognostic (2.43e-2)" "unprognostic (5.93e-2)" "unprognostic (2.33e-2)" "unprognostic (7.43e-2)" "unprognostic (5.77e-2)" "unprognostic (3.88e-1)" "unprognostic (1.07e-1)" UQCC3 "C11orf83, UNQ655" ENSG00000204922 "Ubiquinol-cytochrome c reductase complex assembly factor 3" Q6UW78 11 62670273-62673686 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046851 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Mitochondria" Cytosol "HPA046851: AB_2679839" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.60e-1)" "unprognostic (3.42e-2)" "unprognostic (3.91e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (2.18e-1)" "unprognostic (1.67e-1)" "unprognostic (8.70e-3)" "unprognostic (7.84e-2)" "unprognostic (8.96e-2)" "unprognostic (7.07e-2)" "unprognostic (7.21e-3)" "unprognostic (1.48e-1)" "unprognostic (3.20e-1)" "unprognostic (1.36e-1)" UQCRB "QCR7, QP-C, UQBP, UQCR6" ENSG00000156467 "Ubiquinol-cytochrome c reductase binding protein" P14927 8 96222947-96235546 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1306.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 6148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" HPA043060 Approved NA NA 2200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 38: Heart - Muscle contraction" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA043060: AB_10806376" "unprognostic (5.48e-2)" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (9.47e-3)" "unprognostic (2.15e-1)" "unprognostic (8.41e-2)" "unprognostic (2.79e-1)" "unprognostic (9.20e-2)" "unprognostic (3.98e-1)" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (3.92e-1)" "prognostic favorable (2.90e-4)" "unprognostic (1.01e-1)" "unprognostic (7.54e-2)" "unprognostic (1.07e-1)" "unprognostic (5.66e-3)" UQCRC2 "QCR2, UQCR2" ENSG00000140740 "Ubiquinol-cytochrome c reductase core protein 2" P22695 16 21953288-21983660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 722.2;tongue: 933.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 645.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007998, HPA019146" Enhanced Enhanced Mitochondria NA NA 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Enzymes" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA007998: AB_1858648, HPA019146: AB_1858649" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.49e-3)" "unprognostic (3.35e-1)" "unprognostic (1.26e-2)" "unprognostic (6.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (2.43e-2)" "prognostic favorable (6.58e-9)" "unprognostic (2.33e-1)" "unprognostic (9.78e-3)" "unprognostic (4.67e-3)" "unprognostic (7.36e-2)" UQCRQ "QCR8, QP-C, UQCR7" ENSG00000164405 "Ubiquinol-cytochrome c reductase complex III subunit VII" O14949 5 132866630-132868847 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1301.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 5230.2;Hepatocytes: 5522.5;Proximal tubular cells: 3707.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046693, HPA053323" Approved Enhanced Mitochondria NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA046693: AB_10968453, HPA053323: AB_2682112" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (4.92e-2)" "prognostic favorable (4.23e-4)" "unprognostic (1.09e-1)" "unprognostic (9.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.45e-2)" "unprognostic (1.37e-1)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (3.49e-1)" "unprognostic (1.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (3.37e-2)" VAMP1 "SYB1, VAMP-1" ENSG00000139190 "Vesicle associated membrane protein 1" P23763 12 6462237-6470677 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 192.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 22.3;Inhibitory neurons: 24.5;Oligodendrocytes: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002779, CAB016119, CAB079000" Approved Supported NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 1: T-cells - Immune response" "CAB002779: , CAB016119: AB_628309, CAB079000: " "unprognostic (2.33e-1)" "unprognostic (6.72e-3)" "prognostic unfavorable (6.37e-5)" "unprognostic (8.09e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.22e-2)" "unprognostic (6.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.40e-3)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.04e-11)" "unprognostic (1.47e-2)" "unprognostic (5.99e-2)" "unprognostic (1.62e-1)" "unprognostic (3.65e-2)" VARS2 "DKFZP434L1435, G7a, KIAA1885, VARS2L, VARSL" ENSG00000137411 "Valyl-tRNA synthetase 2, mitochondrial" Q5ST30 6 30914205-30926459 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 14.2;Excitatory neurons: 8.2;Inhibitory neurons: 8.9;Microglial cells: 3.6;Oligodendrocyte precursor cells: 7.7;Oligodendrocytes: 6.7;Plasma cells: 4.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062449, HPA070267" Approved Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 63: Astrocytes - Nervous system maintenance" Mitochondria "HPA062449: AB_2684766, HPA070267: AB_2686245" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "unprognostic (1.96e-3)" "unprognostic (2.50e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-2)" "unprognostic (2.43e-2)" "unprognostic (1.66e-2)" "unprognostic (3.14e-1)" "unprognostic (8.98e-2)" "unprognostic (4.23e-2)" "unprognostic (2.60e-2)" "unprognostic (2.15e-3)" "unprognostic (1.04e-2)" "unprognostic (7.23e-2)" "unprognostic (1.19e-2)" "unprognostic (2.43e-2)" YARS2 "CGI-04, FLJ13995, mt-TyrRS" ENSG00000139131 "Tyrosyl-tRNA synthetase 2" Q9Y2Z4 12 32727490-32755897 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038721, HPA057610, HPA074097" Uncertain Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Mixed function" Mitochondria "Nuclear bodies" "HPA038721: AB_10674837, HPA057610: AB_2683483, HPA074097: AB_2686660" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (2.30e-3)" "unprognostic (1.02e-2)" "unprognostic (2.12e-1)" "unprognostic (5.99e-3)" "prognostic unfavorable (3.19e-5)" "unprognostic (1.41e-2)" "unprognostic (4.98e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-2)" "unprognostic (8.39e-2)" "unprognostic (7.45e-2)" "unprognostic (1.99e-1)" "unprognostic (4.71e-1)" "unprognostic (4.07e-1)" "unprognostic (2.09e-1)"