Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
OPN1LW	"CBBM, CBP, COD5, RCP"	ENSG00000102076	"Opsin 1, long wave sensitive"	P04000	X	154144243-154159032	"Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters"	"Sensory transduction, Vision"	"G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	2568	"retina: 256.7"	"Cell type enriched"	"Detected in some"	25	"Cone photoreceptor cells: 1981.8"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"																		NA	NA				"Cluster 79: Retina - Phototransduction"		"Cluster 44: Photoreceptor cells - Visual perception"													"unprognostic (6.05e-2)"							
OPN1MW	"CBBM, CBD, COD5, GCP, OPN1MW1"	ENSG00000268221	"Opsin 1, medium wave sensitive"	P04001	X	154182596-154196861	"Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins"	"Sensory transduction, Vision"	"G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	133	"retina: 13.3"	"Cell type enriched"	"Detected in some"	51	"Cone photoreceptor cells: 110.3"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"																		NA	NA				"Cluster 79: Retina - Phototransduction"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 44: Photoreceptor cells - Visual perception"																				
OPN1SW	"BCP, BOP, CBT"	ENSG00000128617	"Opsin 1, short wave sensitive"	P03999	7	128772485-128775794	"Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins"	"Sensory transduction, Vision"	"G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	84	"retina: 41.0"	"Cell type enriched"	"Detected in some"	20	"Cone photoreceptor cells: 86.2"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Kidney - Endothelial cells, Prostate - Smooth muscle cells"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA013562, HPA014083"	Enhanced		Approved	"Nucleoplasm,Cytokinetic bridge,Cytosol"		Yes	NA				"Cluster 79: Retina - Phototransduction"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 44: Photoreceptor cells - Visual perception"	"Nucleoplasm, Cytosol"	"Cytokinetic bridge"	"HPA013562: AB_2668850, HPA014083: AB_2668938"	"unprognostic (2.88e-1)"	"unprognostic (5.17e-2)"	"unprognostic (2.22e-2)"	"unprognostic (1.33e-2)"	"unprognostic (2.55e-2)"	"unprognostic (2.16e-1)"	"prognostic unfavorable (8.50e-5)"	"unprognostic (1.13e-1)"	"unprognostic (1.27e-1)"	"unprognostic (6.33e-2)"	"unprognostic (3.79e-1)"	"unprognostic (6.05e-2)"	"prognostic unfavorable (2.26e-8)"	"prognostic unfavorable (5.98e-8)"	"unprognostic (2.53e-1)"	"unprognostic (8.99e-2)"	"prognostic unfavorable (9.33e-4)"
OPN3	"ECPN, encephalopsin, ERO, NMO-1, PPP1R116"	ENSG00000054277	"Opsin 3"	Q9H1Y3	1	241590102-241677376	"G-protein coupled receptors, Predicted membrane proteins"	"Sensory transduction"	"G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 18.7"	"Cell type enhanced"	"Detected in many"		"dendritic cells: 213.1;Early spermatids: 148.4;Extravillous trophoblasts: 282.3;Langerhans cells: 254.6;Late spermatids: 108.3;Syncytiotrophoblasts: 157.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	4	"plasmacytoid DC: 10.0"	"Lineage enriched"	"Detected in many"	5	"dendritic cells: 10.0"	"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Macrophages, Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"							"CAB013682, HPA064443"	Uncertain		Approved	Nucleoplasm		NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 61: Liver - Metabolism"	"Cluster 48: Plasmacytoid dendritic cells - Unknown function"	Nucleoplasm		"CAB013682: , HPA064443: AB_2685267"	"unprognostic (2.41e-2)"	"prognostic unfavorable (3.17e-5)"	"unprognostic (1.75e-2)"	"unprognostic (1.93e-1)"	"prognostic unfavorable (1.70e-4)"	"unprognostic (7.12e-2)"	"unprognostic (5.10e-3)"	"unprognostic (1.24e-2)"	"unprognostic (2.39e-1)"	"unprognostic (4.96e-1)"	"unprognostic (2.66e-2)"	"unprognostic (3.44e-1)"	"unprognostic (9.13e-2)"	"unprognostic (9.15e-3)"	"unprognostic (2.61e-2)"	"unprognostic (7.12e-2)"	"unprognostic (9.44e-3)"
OPN4	"melanopsin, MOP"	ENSG00000122375	"Opsin 4"	Q9UHM6	10	86654547-86666848	"G-protein coupled receptors, Predicted membrane proteins, Transporters"	"Biological rhythms, Sensory transduction"	"G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 7.9;skeletal muscle: 2.5"	"Cell type enhanced"	"Detected in some"		"Excitatory neurons: 2.8;Horizontal cells: 1.3;Inhibitory neurons: 1.8;Smooth muscle cells: 1.6"	"Not detected"	"Not detected"			"Region enhanced"	"Detected in many"		"basal ganglia: 7.9"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"				"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA039147	Approved					NA	NA				"Cluster 47: Non-specific - Unknown function"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 72: Smooth muscle cells - ECM organization"			"HPA039147: AB_10673304"	"unprognostic (3.67e-3)"	"unprognostic (1.40e-2)"	"unprognostic (3.02e-2)"	"unprognostic (1.62e-1)"	"unprognostic (7.03e-3)"	"unprognostic (2.89e-2)"		"unprognostic (3.26e-1)"	"unprognostic (9.54e-2)"	"unprognostic (5.68e-2)"	"unprognostic (8.88e-3)"		"unprognostic (1.93e-6)"	"unprognostic (4.10e-2)"		"unprognostic (5.58e-2)"	"unprognostic (6.76e-2)"
OPN5	"dJ402H5.1, neuropsin, TMEM13"	ENSG00000124818	"Opsin 5"	Q6U736	6	47781982-47832780	"G-protein coupled receptors, Predicted membrane proteins"	"Sensory transduction, Vision"	"G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	6	"testis: 2.6"	"Group enriched"	"Detected in some"	11	"Early spermatids: 28.8;Late spermatids: 26.1;Spermatocytes: 10.3"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Testis - Early spermatids"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA026084	Supported					NA	NA				"Cluster 78: Testis - Spermatogenesis"	"Cluster 10: Ovarian & Endometrial cancers - Unknown function"	"Cluster 6: Late spermatids - Spermatogenesis"			"HPA026084: AB_2671807"					"unprognostic (1.95e-1)"								"unprognostic (6.18e-2)"		"unprognostic (4.84e-1)"	"unprognostic (1.07e-1)"	
RGR	RP44	ENSG00000148604	"Retinal G protein coupled receptor"	P47804	10	84230666-84259960	"Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Sensory transduction, Vision"	"G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer"	"Disease variant, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	9	"retina: 139.0"	"Cell type enriched"	"Detected in some"	40	"Muller glia cells: 1379.9"	"Cancer enriched"	"Detected in single"	4	"glioma: 0.9"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Testis - Early spermatids, Testis - Late spermatids"	"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	6	"midbrain: 23.4;olfactory bulb: 49.7;thalamus: 27.3"	HPA059149			Approved	"Vesicles,Plasma membrane,Cytosol"		NA	NA				"Cluster 77: Retina - Visual perception"	"Cluster 41: Non-specific - Cilium assembly"	"Cluster 68: Muller glia cells - Visual perception"	Vesicles	"Plasma membrane, Cytosol"	"HPA059149: "	"unprognostic (9.28e-2)"		"unprognostic (1.05e-1)"	"unprognostic (1.37e-1)"	"unprognostic (9.53e-2)"				"unprognostic (4.57e-2)"	"unprognostic (1.57e-1)"				"unprognostic (1.59e-1)"	"unprognostic (1.97e-1)"		
RHO	"CSNBAD1, OPN2, RP4"	ENSG00000163914	Rhodopsin	P08100	3	129528639-129535344	"Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters"	"Sensory transduction, Vision"	"G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer"	"Congenital stationary night blindness, Disease variant, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	5994	"retina: 4062.1"	"Cell type enriched"	"Detected in some"	4	"Rod photoreceptor cells: 3817.8"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"				"Region enriched"	"Detected in some"	4	"hippocampal formation: 9.7"	"Region enhanced"	"Detected in single"		"hippocampal formation: 1.1"	"HPA013440, CAB022486, CAB034887, CAB034888"	Enhanced					NA	NA				"Cluster 79: Retina - Phototransduction"		"Cluster 44: Photoreceptor cells - Visual perception"			"CAB022486: , CAB034887: AB_785511, CAB034888: AB_785512, HPA013440: AB_2668844"	"unprognostic (4.32e-2)"			"unprognostic (1.21e-1)"	"unprognostic (1.68e-1)"		"unprognostic (1.83e-1)"	"unprognostic (2.87e-1)"		"unprognostic (1.94e-1)"			"unprognostic (9.19e-11)"	"unprognostic (4.24e-2)"	"unprognostic (1.84e-1)"	"unprognostic (2.91e-1)"	
RRH	peropsin	ENSG00000180245	"Retinal pigment epithelium-derived rhodopsin homolog"	O14718	4	109827972-109849123	"G-protein coupled receptors, Predicted membrane proteins"	"Sensory transduction"	"G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	112	"retina: 75.6"	"Cell type enriched"	"Detected in some"	19	"Muller glia cells: 202.1"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"				"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"									NA	NA				"Cluster 79: Retina - Phototransduction"	"Cluster 52: Spermatids - Smell perception"	"Cluster 68: Muller glia cells - Visual perception"				"unprognostic (1.59e-1)"	"unprognostic (2.47e-2)"	"unprognostic (4.94e-2)"	"unprognostic (1.96e-2)"	"unprognostic (1.48e-1)"	"unprognostic (5.25e-2)"	"unprognostic (7.56e-2)"	"unprognostic (8.47e-2)"	"unprognostic (2.33e-1)"	"unprognostic (1.86e-2)"	"unprognostic (2.03e-2)"	"unprognostic (1.62e-3)"	"unprognostic (4.65e-1)"	"unprognostic (4.38e-3)"	"unprognostic (1.22e-1)"	"unprognostic (2.27e-1)"	"unprognostic (3.18e-2)"