Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
CHEK2	"bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53"	ENSG00000183765	"Checkpoint kinase 2"	O96017	22	28687743-28742422	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Transcription, Transcription regulation"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Spermatogonia: 18.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skin - Mitotic cells (Skin), Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA001878, CAB002030"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Unknown function"	"Cluster 52: Endometrial stromal cells - ECM organization"	Nucleoplasm	"Golgi apparatus"	"CAB002030: AB_563660, HPA001878: AB_1078514"	"unprognostic (1.54e-1)"	"unprognostic (2.20e-1)"	"unprognostic (5.83e-2)"	"unprognostic (2.93e-2)"	"unprognostic (2.42e-1)"	"unprognostic (3.83e-2)"	"unprognostic (1.49e-3)"	"unprognostic (5.08e-3)"	"unprognostic (3.33e-3)"	"unprognostic (9.62e-3)"	"unprognostic (1.28e-2)"	"unprognostic (3.13e-1)"	"prognostic unfavorable (7.80e-9)"	"unprognostic (2.38e-2)"	"unprognostic (1.78e-1)"	"unprognostic (7.27e-2)"	"unprognostic (6.79e-3)"
CHRM3		ENSG00000133019	"Cholinergic receptor muscarinic 3"	P20309	1	239386565-239915452	"Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 11.8;salivary gland: 17.5"	"Group enriched"	"Detected in many"	4	"Excitatory neurons: 791.9;Inhibitory neurons: 606.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Heart muscle - Smooth muscle cells, Skin - Eccrine sweat gland cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA024106, HPA048036"	Approved		Supported	"Plasma membrane"		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 22: Non-specific - Unknown function"	"Cluster 2: DU4475 - Unknown function"	"Cluster 38: Neurons - Neuronal signaling"	"Plasma membrane"		"HPA024106: AB_1854211, HPA048036: AB_2680238"	"unprognostic (1.63e-1)"	"unprognostic (4.82e-2)"	"unprognostic (1.05e-1)"	"unprognostic (4.11e-3)"	"unprognostic (3.48e-3)"	"unprognostic (5.81e-2)"	"unprognostic (2.30e-3)"	"unprognostic (5.18e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.27e-1)"	"unprognostic (6.29e-2)"	"unprognostic (6.44e-2)"	"unprognostic (5.34e-4)"	"unprognostic (3.04e-2)"	"unprognostic (2.67e-1)"	"unprognostic (1.02e-1)"	"unprognostic (4.88e-2)"
EDNRB	"ETB, HSCR, HSCR2"	ENSG00000136160	"Endothelin receptor type B"	P24530	13	77895481-77975529	"Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"	"Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 127.8"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 110.0;Astrocytes: 122.4;Endothelial cells: 80.0;Leydig cells: 83.6;Melanocytes: 175.9;Muller glia cells: 104.0;Sertoli cells: 105.0;Smooth muscle cells: 83.3"	"Cancer enhanced"	"Detected in all"		"melanoma: 127.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	12	"Myeloma: 93.7;skin cancer: 125.5"	"Liver - Hepatic stellate cells, Testis - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017842, HPA027546"	Approved		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 72: Smooth muscle cells - ECM organization"	"Plasma membrane"	Cytosol	"CAB017842: , HPA027546: AB_2672327"	"unprognostic (7.75e-2)"	"unprognostic (6.73e-2)"	"unprognostic (1.41e-3)"	"unprognostic (2.59e-2)"	"unprognostic (8.37e-2)"	"unprognostic (2.45e-3)"	"unprognostic (4.17e-3)"	"unprognostic (5.43e-2)"	"unprognostic (1.02e-1)"	"unprognostic (1.38e-2)"	"unprognostic (3.40e-2)"	"unprognostic (3.01e-2)"	"prognostic favorable (7.20e-5)"	"unprognostic (1.59e-2)"	"unprognostic (3.86e-2)"	"unprognostic (4.58e-2)"	"unprognostic (6.77e-3)"
EPCAM	"17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1"	ENSG00000119888	"Epithelial cell adhesion molecule"	P16422	2	47345158-47387601	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Tumor antigen"	"Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 806.0"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 2396.3;Enteroendocrine cells: 962.1;Intestinal goblet cells: 1437.9;Paneth cells: 2254.7;Proximal enterocytes: 2636.9;Undifferentiated cells: 1431.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in all"		"colorectal cancer: 691.3"	"Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in many"			"CAB003809, HPA026761, CAB030012, CAB055098, HPA067463"	Enhanced		Supported	"Plasma membrane"		NA	NA		22000		"Cluster 9: Intestine - Unknown function"	"Cluster 19: Stomach & Colon cancer - Absorption"	"Cluster 50: Enterocytes - Absorption"	"Plasma membrane"		"CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846"	"unprognostic (6.79e-2)"	"unprognostic (2.28e-1)"	"unprognostic (1.59e-2)"	"unprognostic (1.16e-2)"	"unprognostic (1.61e-1)"	"unprognostic (3.49e-2)"	"unprognostic (2.01e-1)"	"unprognostic (3.61e-2)"	"unprognostic (3.40e-1)"	"prognostic favorable (3.30e-4)"	"unprognostic (5.27e-2)"	"unprognostic (3.28e-2)"	"prognostic favorable (1.04e-6)"	"unprognostic (6.38e-3)"	"unprognostic (1.28e-1)"	"unprognostic (6.45e-3)"	"unprognostic (6.08e-2)"
FH		ENSG00000091483	"Fumarate hydratase"	P07954	1	241497603-241519755	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Tricarboxylic acid cycle"	Lyase	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 276.4"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 209.0;Early spermatids: 247.9;Syncytiotrophoblasts: 174.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017785, HPA025770, HPA025948, HPA027341"	Enhanced	Supported	Enhanced	Mitochondria		NA	NA		1800000	"Cluster 44: Non-specific - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 18: Non-specific - RNA binding"	"Cluster 18: Non-specific - Mixed function"	Mitochondria		"CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222"	"unprognostic (1.03e-2)"	"unprognostic (3.82e-2)"	"unprognostic (9.46e-3)"	"unprognostic (2.18e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.55e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.85e-2)"	"unprognostic (1.27e-2)"	"unprognostic (1.09e-1)"	"prognostic favorable (2.76e-7)"	"unprognostic (1.05e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.24e-2)"
FLCN	"BHD, DENND8B, MGC17998, MGC23445"	ENSG00000154803	Folliculin	Q8NFG4	17	17212212-17237188	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB015158, HPA028760"	Supported		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 72: Non-specific - Transcription"	"Cluster 32: Myeloid leukemia - Oxygen transport"	"Cluster 65: Fibroblasts - ECM organization"	Cytosol	"Plasma membrane"	"CAB015158: AB_2231645, HPA028760: AB_10601323"	"unprognostic (1.99e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.74e-1)"	"unprognostic (3.85e-2)"	"unprognostic (3.69e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.32e-1)"	"unprognostic (3.58e-2)"	"unprognostic (3.90e-1)"	"prognostic favorable (4.49e-4)"	"unprognostic (6.45e-3)"	"unprognostic (2.55e-3)"	"unprognostic (1.92e-1)"	"unprognostic (9.71e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.65e-1)"
MLH1	"COCA2, FCC2, HNPCC, HNPCC2"	ENSG00000076242	"MutL homolog 1"	P40692	3	36993350-37050846	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013294, HPA052707, HPA060714, CAB070868"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 5: Non-specific - Unknown function"	"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis"	Nucleoplasm		"CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348"	"unprognostic (1.26e-2)"	"unprognostic (3.88e-3)"	"unprognostic (2.36e-2)"	"unprognostic (1.82e-1)"	"unprognostic (3.33e-2)"	"unprognostic (1.05e-1)"	"prognostic unfavorable (8.24e-5)"	"unprognostic (3.36e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.32e-1)"	"unprognostic (8.54e-2)"	"unprognostic (8.63e-3)"	"unprognostic (2.10e-3)"	"unprognostic (4.37e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.02e-2)"	"unprognostic (8.86e-2)"
MLH3		ENSG00000119684	"MutL homolog 3"	Q9UHC1	14	75013769-75051532	"Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Disease variant, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Oligodendrocytes: 100.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA060570			Approved	Nucleoplasm		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 46: Non-specific - Unknown function"	"Cluster 4: Platelets - Platelet activation"	Nucleoplasm		"HPA060570: AB_2684323"	"unprognostic (2.94e-1)"	"unprognostic (6.70e-3)"	"unprognostic (7.14e-3)"	"unprognostic (7.35e-2)"	"unprognostic (7.38e-2)"	"unprognostic (1.55e-1)"	"unprognostic (1.49e-2)"	"unprognostic (1.62e-2)"	"unprognostic (3.77e-2)"	"unprognostic (6.68e-2)"	"unprognostic (1.93e-2)"	"unprognostic (8.42e-2)"	"unprognostic (3.53e-1)"	"unprognostic (2.89e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.64e-1)"	"unprognostic (7.11e-2)"
MSH2	"COCA1, HNPCC, HNPCC1"	ENSG00000095002	"MutS homolog 2"	P43246	2	47403067-47663146	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 84.4"	"Cancer enhanced"	"Detected in all"		"testis cancer: 46.2"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009572, HPA066845, CAB070867, CAB080131"	Supported		Supported	Nucleoplasm,Vesicles		NA	Yes		28000	"Cluster 48: NK-cells - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	Vesicles	"CAB009572: AB_2144828, CAB070867: , CAB080131: , HPA066845: AB_2732752"	"unprognostic (2.35e-1)"	"unprognostic (1.54e-2)"	"unprognostic (2.89e-3)"	"prognostic unfavorable (4.44e-4)"	"unprognostic (2.23e-1)"	"unprognostic (6.31e-3)"	"prognostic unfavorable (1.72e-9)"	"unprognostic (1.77e-1)"	"unprognostic (7.09e-3)"	"unprognostic (8.57e-2)"	"prognostic unfavorable (4.63e-4)"	"unprognostic (5.38e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.20e-3)"	"unprognostic (5.74e-1)"	"unprognostic (8.46e-2)"	"unprognostic (1.48e-1)"
MSH6	GTBP	ENSG00000116062	"MutS homolog 6"	P52701	2	47695530-47810063	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 113.3;Theca cells: 92.3"	"Cancer enhanced"	"Detected in all"		"testis cancer: 31.8"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009091, HPA028376, HPA028446, CAB070870"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"		NA	Yes		15000	"Cluster 44: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 17: Granulosa cells - Transcription regulation"	Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182"	"unprognostic (5.10e-2)"	"unprognostic (5.87e-3)"	"unprognostic (3.29e-2)"	"prognostic unfavorable (1.34e-4)"	"unprognostic (1.98e-1)"	"unprognostic (3.09e-2)"	"prognostic unfavorable (7.86e-4)"	"unprognostic (1.79e-1)"	"unprognostic (2.35e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.74e-3)"	"unprognostic (8.99e-2)"	"prognostic unfavorable (1.06e-7)"	"unprognostic (1.22e-1)"	"unprognostic (2.31e-1)"	"unprognostic (9.68e-2)"	"unprognostic (3.48e-2)"
PMS2	"H_DJ0042M02.9, HNPCC4, MLH4, PMSL2"	ENSG00000122512	"PMS1 homolog 2, mismatch repair system component"	P54278	7	5970925-6009106	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010235, HPA070310"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 34: Non-specific - Transcription"	"Cluster 63: Non-specific - Unknown function"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	Cytosol	"CAB010235: AB_2167281, HPA070310: AB_2686250"	"unprognostic (5.13e-2)"	"unprognostic (6.55e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.43e-3)"	"unprognostic (5.14e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.36e-2)"	"unprognostic (1.02e-1)"	"unprognostic (7.43e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.86e-1)"	"unprognostic (7.38e-2)"	"prognostic favorable (1.23e-5)"	"unprognostic (5.31e-2)"	"unprognostic (2.01e-2)"	"unprognostic (3.67e-2)"	"unprognostic (2.81e-2)"
PRKAR1A	"CNC1, PRKAR1, TSE1"	ENSG00000108946	"Protein kinase cAMP-dependent type I regulatory subunit alpha"	P10644	17	68511780-68551319	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 776.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB019378, HPA049979"	Approved		Approved	Cytosol		NA	NA		1800000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 16: Skin cancer - Melanocyte processes"	"Cluster 77: Cardiomyocytes - Muscle contraction"	Cytosol		"CAB019378: , HPA049979: AB_2680980"	"unprognostic (8.69e-2)"	"unprognostic (6.97e-2)"	"unprognostic (5.34e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.68e-1)"	"unprognostic (4.39e-2)"	"unprognostic (2.61e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.27e-1)"	"unprognostic (2.30e-1)"	"unprognostic (1.19e-2)"	"unprognostic (5.55e-2)"	"unprognostic (8.56e-3)"	"unprognostic (6.26e-2)"	"unprognostic (6.92e-2)"	"unprognostic (3.29e-2)"	"unprognostic (1.11e-1)"
SLC29A3	"ENT3, FLJ11160"	ENSG00000198246	"Solute carrier family 29 member 3"	Q9BZD2	10	71319259-71381423	"Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters"	Transport		"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 46.7;Extravillous trophoblasts: 49.8;Hofbauer cells: 30.2;Syncytiotrophoblasts: 33.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Macrophages, Adipose visceral - Adipose progenitor cells, Lung - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA046085, HPA054976, HPA057905"	Approved		Enhanced	"Golgi apparatus,Vesicles"		NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 28: Cytotrophoblasts - Unknown function"	"Golgi apparatus, Vesicles"		"HPA046085: AB_2679531, HPA054976: AB_2682659, HPA057905: AB_2683550"	"unprognostic (1.73e-1)"	"unprognostic (2.38e-3)"	"unprognostic (3.23e-3)"	"unprognostic (1.07e-1)"	"unprognostic (3.06e-2)"	"unprognostic (1.73e-2)"	"prognostic unfavorable (6.07e-6)"	"unprognostic (1.28e-1)"	"unprognostic (4.71e-1)"	"unprognostic (1.81e-1)"	"unprognostic (2.53e-1)"	"unprognostic (3.80e-2)"	"prognostic unfavorable (5.53e-5)"	"unprognostic (3.37e-1)"	"unprognostic (1.36e-1)"	"prognostic favorable (1.16e-4)"	"unprognostic (3.43e-3)"
SMARCA4	"BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2"	ENSG00000127616	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4"	P51532	19	10960932-11079426	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004208, HPA048340"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 53: Non-specific - mRNA processing"	"Cluster 18: Non-specific - Mixed function"	"Nucleoplasm, Nucleoli fibrillar center, Nucleoli rim"		"CAB004208: AB_626762, HPA048340: "	"unprognostic (2.68e-1)"	"unprognostic (4.85e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.43e-3)"	"unprognostic (1.40e-1)"	"unprognostic (6.33e-3)"	"prognostic unfavorable (1.11e-4)"	"unprognostic (7.19e-2)"	"unprognostic (7.29e-2)"	"unprognostic (1.73e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.15e-2)"	"unprognostic (6.80e-3)"	"unprognostic (6.83e-3)"	"unprognostic (5.44e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.29e-1)"
SMARCB1	"BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1"	ENSG00000099956	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1"	Q12824	22	23786931-23838009	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease variant, Hypotrichosis, Intellectual disability, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Extravillous trophoblasts: 253.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in many"		"Myeloma: 21.4"	"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009196, HPA018248, HPA019127"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center"		NA	NA			"Cluster 43: B-cells - Humoral immune response"	"Cluster 72: Non-specific - Transcription"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 62: B-cells - B-cell activation"	Nucleoplasm	"Nucleoli fibrillar center"	"CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165"	"unprognostic (2.15e-1)"	"unprognostic (5.62e-2)"	"unprognostic (6.60e-3)"	"unprognostic (1.63e-2)"	"unprognostic (4.01e-3)"	"unprognostic (2.14e-1)"	"prognostic unfavorable (6.52e-4)"	"unprognostic (4.10e-1)"	"unprognostic (1.86e-1)"	"unprognostic (1.03e-2)"	"unprognostic (2.10e-2)"	"unprognostic (4.43e-3)"	"prognostic favorable (1.14e-6)"	"unprognostic (1.24e-1)"	"unprognostic (4.58e-2)"	"unprognostic (4.57e-2)"	"unprognostic (7.04e-2)"
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687538	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876"	Enhanced		Enhanced	Nucleoplasm,Vesicles,Cytosol		Yes	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 49: Non-specific - Unknown function"	"Cluster 39: Non-specific - Translation"	Nucleoplasm	"Vesicles, Cytosol"	"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, HPA051244: AB_2681403, HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favorable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavorable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"