Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
CASR	"FHH, GPRC2A, HHC, HHC1, NSHPT"	ENSG00000036828	"Calcium sensing receptor"	P41180	3	122183668-122291629	"Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters"		"G-protein coupled receptor, Receptor, Transducer"	"Disease variant, Epilepsy, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	29	"parathyroid gland: 654.4"	"Cell type enhanced"	"Detected in some"		"Cholangiocytes: 48.1;Enteroendocrine cells: 12.0;Granulosa cells: 20.7;Pancreatic endocrine cells: 17.2"	"Cancer enriched"	"Detected in some"	7	"pancreatic cancer: 5.5"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enriched"	"Detected in single"	9	"thyroid cancer: 6.8"	"Kidney - Ascending Loop of Henle cells, Stomach - Gastric enteroendocrine cells, Thyroid - Parafollicular cells"	"Low region specificity"	"Detected in some"			"Not detected"	"Not detected"			"HPA039686, HPA050335"	Enhanced					NA	NA				"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction"	"Cluster 17: Granulosa cells - Transcription regulation"			"HPA039686: AB_10673536, HPA050335: AB_2681092"		"unprognostic (1.97e-2)"	"unprognostic (7.40e-2)"	"unprognostic (8.20e-4)"	"unprognostic (3.15e-1)"	"unprognostic (8.55e-4)"	"unprognostic (1.58e-1)"	"unprognostic (7.32e-2)"		"unprognostic (7.67e-2)"	"unprognostic (1.62e-1)"	"unprognostic (1.48e-1)"	"unprognostic (1.91e-5)"	"unprognostic (2.72e-1)"	"unprognostic (2.26e-1)"		"unprognostic (1.24e-2)"
CDC73	"C1orf28, FIHP, HRPT1, HRPT2, parafibromin"	ENSG00000134371	"Cell division cycle 73"	Q6P1J9	1	193121983-193254815	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway"		"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002326, CAB016359, HPA069324"	Supported		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 59: Fibroblasts - Metabolism"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	Cytosol	"CAB016359: AB_628102, HPA002326: , HPA069324: "	"unprognostic (4.41e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.30e-2)"	"unprognostic (2.88e-3)"	"unprognostic (3.53e-2)"	"unprognostic (2.48e-3)"	"unprognostic (5.74e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.40e-1)"	"unprognostic (7.23e-3)"	"unprognostic (2.17e-1)"	"unprognostic (5.44e-3)"	"unprognostic (3.47e-1)"	"unprognostic (2.49e-1)"	"unprognostic (6.73e-3)"	"unprognostic (2.98e-3)"
GCM2	"GCMB, hGCMb"	ENSG00000124827	"Glial cells missing transcription factor 2"	O75603	6	10873223-10882041	"Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Developmental protein, DNA-binding"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	358	"parathyroid gland: 262.9"	"Cell type enhanced"	"Detected in some"		"Astrocytes: 1.3;Early spermatids: 2.5;Excitatory neurons: 2.3;Horizontal cells: 1.9;Inhibitory neurons: 1.7;Oligodendrocyte precursor cells: 1.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"				"Not detected"	"Not detected"			"Not detected"	"Not detected"									NA	NA				"Cluster 48: Parathyroid gland - membrane proteins"		"Cluster 57: Early spermatids - Flagellum & Golgi organization"								"unprognostic (1.55e-1)"					"unprognostic (4.94e-1)"				"unprognostic (2.18e-2)"	"unprognostic (7.17e-2)"	"unprognostic (2.63e-3)"	
GNAS	"GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI"	ENSG00000087460	"GNAS complex locus"	"O95467, P63092, P84996, Q5JWF2"	20	58839718-58911192	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		Transducer	"Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010337, HPA018122, HPA027478, HPA028386"	Uncertain		Approved	"Nucleoplasm,Plasma membrane,Cytosol"	"Intracellular and membrane"	NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 12: Non-specific - Chromatin organization"	Nucleoplasm	"Plasma membrane, Cytosol"	"CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983"	"unprognostic (7.48e-2)"	"unprognostic (1.41e-1)"	"unprognostic (3.90e-2)"	"unprognostic (4.77e-2)"	"unprognostic (8.37e-3)"	"unprognostic (2.82e-2)"	"unprognostic (4.53e-3)"	"unprognostic (8.01e-2)"	"unprognostic (4.29e-2)"	"prognostic favorable (8.76e-4)"	"unprognostic (2.07e-2)"	"unprognostic (1.58e-1)"	"prognostic unfavorable (3.49e-4)"	"unprognostic (5.24e-3)"	"unprognostic (1.61e-1)"	"unprognostic (8.25e-2)"	"unprognostic (1.36e-1)"
MEN1		ENSG00000133895	"Menin 1"	O00255	11	64803510-64811294	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA030342	Uncertain		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 16: Non-specific - RNA binding"	Nucleoplasm	Cytosol	"HPA030342: AB_10610138"	"unprognostic (2.06e-1)"	"unprognostic (1.76e-1)"	"unprognostic (3.78e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.05e-1)"	"unprognostic (8.41e-2)"	"prognostic unfavorable (1.08e-4)"	"unprognostic (2.66e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.42e-2)"	"unprognostic (4.96e-2)"	"unprognostic (1.36e-1)"	"unprognostic (7.39e-2)"	"prognostic favorable (6.31e-5)"	"unprognostic (1.40e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.76e-1)"
PTH	PTH1	ENSG00000152266	"Parathyroid hormone"	P01270	11	13492054-13496181	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins"		Hormone	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	245	"parathyroid gland: 50184.7"	"Cell type enhanced"	"Detected in some"		"Inhibitory neurons: 1.0;Oligodendrocytes: 2.8"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"				"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"CAB000072, CAB023409, CAB026363, HPA048540"	Enhanced				"Secreted to blood"	NA	NA	28000			"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 41: Non-specific - Cilium assembly"	"Cluster 37: Neurons - Neuronal signaling"			"CAB000072: , CAB023409: AB_619175, CAB026363: , HPA048540: AB_2680435"																	
STX16	"hsyn16, SYN16"	ENSG00000124222	"Syntaxin 16"	O14662	20	58651253-58679526	"Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"							"HPA041019, HPA042033"	Uncertain		Enhanced	Vesicles		NA	NA			"Cluster 34: Basophils - Unknown function"	"Cluster 50: Non-specific - Ribosome"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 64: Non-specific - Transcription"	Vesicles		"HPA041019: AB_10964273, HPA042033: AB_10963935"	"unprognostic (7.52e-2)"	"unprognostic (1.91e-1)"	"unprognostic (7.96e-2)"	"unprognostic (1.35e-2)"	"unprognostic (1.51e-1)"	"unprognostic (2.12e-1)"	"prognostic unfavorable (4.18e-4)"	"unprognostic (7.32e-2)"	"unprognostic (5.11e-2)"	"unprognostic (3.51e-2)"	"unprognostic (2.80e-3)"	"unprognostic (2.41e-2)"	"prognostic unfavorable (1.11e-16)"	"unprognostic (3.35e-2)"	"unprognostic (1.53e-1)"	"unprognostic (1.56e-1)"	"unprognostic (5.89e-2)"
TRPV6	"CaT1, ECAC2"	ENSG00000165125	"Transient receptor potential cation channel subfamily V member 6"	Q9H1D0	7	142871208-142885745	"Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels"	"Calcium transport, Ion transport, Transport"	"Calcium channel, Calmodulin-binding, Ion channel"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"pancreas: 38.3;prostate: 23.5;salivary gland: 69.3"	"Cell type enhanced"	"Detected in many"		"Ductal cells: 84.9;Late spermatids: 41.5;Prostatic glandular cells: 54.3;Serous glandular cells: 59.4"	"Cancer enriched"	"Detected in many"	5	"prostate cancer: 16.1"	"Low region specificity"	"Detected in single"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"breast cancer: 7.6;prostate cancer: 10.2"	"Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Prostate - Prostate glandular cells, Testis - Late spermatids"	"Low region specificity"	"Detected in single"							HPA062864	Approved					NA	NA				"Cluster 24: Salivary gland - Salivary secretion"	"Cluster 24: Prostate cancer - Lipid metabolism"	"Cluster 21: Serous glandular cells - Salivary secretion"			"HPA062864: AB_2684885"	"unprognostic (9.85e-2)"	"unprognostic (1.60e-2)"	"unprognostic (6.29e-2)"	"unprognostic (8.72e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.14e-1)"	"unprognostic (7.11e-2)"	"unprognostic (5.43e-2)"	"unprognostic (3.50e-1)"	"unprognostic (4.56e-2)"	"unprognostic (3.89e-2)"	"unprognostic (3.27e-2)"	"unprognostic (8.49e-2)"	"unprognostic (9.39e-3)"	"unprognostic (1.69e-1)"	"unprognostic (7.17e-3)"	"unprognostic (3.53e-2)"