Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
BRAF	BRAF1	ENSG00000157764	"B-Raf proto-oncogene, serine/threonine kinase"	P15056	7	140719327-140924929	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins"		"Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 248.6;Inhibitory neurons: 236.7;Oligodendrocyte precursor cells: 197.4;Oligodendrocytes: 191.2;Syncytiotrophoblasts: 190.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001328, CAB004552, HPA071048"	Supported		Approved	Vesicles,Cytosol		No	No			"Cluster 15: NK-cells - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 31: Non-specific - Transcription"	"Cluster 1: T-cells - Immune response"	Vesicles	Cytosol	"CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336"	"unprognostic (2.98e-3)"	"unprognostic (5.66e-2)"	"unprognostic (2.20e-2)"	"unprognostic (2.66e-3)"	"unprognostic (2.44e-1)"	"unprognostic (1.48e-2)"	"unprognostic (2.07e-2)"	"unprognostic (4.23e-2)"	"unprognostic (4.07e-2)"	"unprognostic (1.58e-2)"	"unprognostic (6.53e-2)"	"unprognostic (1.91e-2)"	"unprognostic (3.79e-3)"	"unprognostic (2.08e-1)"	"unprognostic (1.76e-1)"	"unprognostic (8.01e-2)"	"unprognostic (5.46e-2)"
CDK4	PSK-J3	ENSG00000135446	"Cyclin dependent kinase 4"	P11802	12	57747727-57756013	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Cancer enriched"	"Detected in all"	5	"glioma: 175.8"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006024, CAB013116, CAB069405"	Supported		Supported	"Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol"		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 42: Sarcoma - Muscle contraction"	"Cluster 16: Non-specific - RNA binding"	Cytosol	"Nucleoplasm, Nuclear membrane, Nucleoli"	"CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: AB_2667497"	"unprognostic (8.88e-2)"	"unprognostic (2.53e-1)"	"unprognostic (5.27e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.10e-1)"	"prognostic unfavorable (2.09e-7)"	"unprognostic (7.39e-2)"	"unprognostic (3.23e-3)"	"unprognostic (2.93e-2)"	"unprognostic (3.19e-2)"	"unprognostic (9.10e-2)"	"prognostic unfavorable (3.15e-5)"	"unprognostic (3.32e-1)"	"unprognostic (1.67e-1)"	"unprognostic (3.64e-1)"	"unprognostic (1.57e-2)"
CDKN2A	"ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf"	ENSG00000147889	"Cyclin dependent kinase inhibitor 2A"	"P42771, Q8N726"	9	21967752-21995301	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 31.7;pituitary gland: 33.7"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 159.5;Early spermatids: 226.2;Ionocytes: 137.6;Late spermatids: 448.0;Respiratory ciliated cells: 183.1"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 49.9;ovarian cancer: 57.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"T-reg: 37.4"	"Group enriched"	"Detected in many"	6	"B-cells: 15.6;T-cells: 37.4"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 538.8"	"Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids"					"Low region specificity"	"Detected in some"			"CAB000093, CAB000445, CAB018232, HPA073143"	Enhanced		Supported	Nucleoplasm,Cytosol		NA	NA		18000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 48: Non-specific - RNA binding"	"Cluster 74: Pancreatic cells - Mixed function"	Nucleoplasm	Cytosol	"CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA073143: "	"unprognostic (3.41e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.00e-3)"	"prognostic unfavorable (1.82e-7)"	"unprognostic (5.22e-2)"	"prognostic favorable (5.19e-4)"	"prognostic unfavorable (2.17e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (5.76e-7)"	"unprognostic (9.41e-2)"	"unprognostic (1.22e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.55e-1)"
CDKN2B	"CDK4I, INK4B, MTS2, P15, p15INK4b, TP15"	ENSG00000147883	"Cyclin dependent kinase inhibitor 2B"	P42772	9	22002903-22009305	"Human disease related genes, Predicted intracellular proteins"	"Cell cycle"		"Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 36.2;intestine: 30.9"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 86.8;Distal enterocytes: 144.9;Proximal enterocytes: 129.1;Squamous epithelial cells: 168.6;Suprabasal keratinocytes: 106.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	10	"classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0"	"Lineage enriched"	"Detected in single"	17	"monocytes: 9.0"	"Cancer enhanced"	"Detected in many"		"cervical cancer: 55.8"	"Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Endothelial cells, Skin - Outer root sheath cells, Testis - Early spermatids"	"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"CAB000349, HPA052838, HPA063327, HPA073143"	Uncertain		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 37: Intestine - Unknown function"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 50: Enterocytes - Absorption"	Nucleoplasm	Cytosol	"CAB000349: , HPA052838: , HPA063327: AB_2684987, HPA073143: "	"unprognostic (2.30e-1)"	"unprognostic (9.23e-2)"	"unprognostic (2.19e-1)"	"prognostic unfavorable (4.47e-6)"	"unprognostic (2.10e-1)"	"unprognostic (7.40e-2)"	"prognostic unfavorable (1.49e-4)"	"unprognostic (2.01e-1)"	"unprognostic (3.03e-2)"	"unprognostic (3.19e-2)"	"unprognostic (1.13e-1)"	"unprognostic (1.36e-1)"	"prognostic unfavorable (1.03e-4)"	"unprognostic (9.14e-3)"	"unprognostic (1.29e-1)"	"unprognostic (2.72e-1)"	"unprognostic (7.28e-2)"
FAS	"APO-1, APT1, CD95, FAS1, TNFRSF6"	ENSG00000026103	"Fas cell surface death receptor"	P25445	10	88990531-89017059	"Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins"	Apoptosis	"Calmodulin-binding, Receptor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 66.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 114.7"	"Group enriched"	"Detected in all"	5	"granulocytes: 114.7;T-cells: 96.2"	"Low cancer specificity"	"Detected in all"			"Heart muscle - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA027444	Uncertain		Supported	"Nuclear bodies,Plasma membrane,Cytosol"	"Secreted to blood"	NA	NA	11900000	420000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling"	"Cluster 1: T-cells - Immune response"	"Plasma membrane"	"Nuclear bodies, Cytosol"	"HPA027444: AB_10601378"	"unprognostic (6.84e-2)"	"unprognostic (2.88e-3)"	"unprognostic (8.38e-3)"	"unprognostic (1.94e-1)"	"unprognostic (2.35e-2)"	"unprognostic (9.56e-2)"	"unprognostic (7.00e-2)"	"unprognostic (2.05e-1)"	"unprognostic (3.01e-1)"	"unprognostic (7.70e-2)"	"unprognostic (1.26e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.52e-3)"	"unprognostic (2.10e-1)"	"unprognostic (2.32e-2)"	"unprognostic (4.95e-3)"	"unprognostic (1.65e-1)"
HRAS	HRAS1	ENSG00000174775	"HRas proto-oncogene, GTPase"	P01112	11	532242-537287	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Suprabasal keratinocytes: 203.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"non-classical monocyte: 4.0"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002015, HPA049830, HPA070222"	Approved		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 22: Squamous epithelial cells - Keratinization"	"Nucleoplasm, Cytosol"		"CAB002015: , HPA049830: AB_2680903, HPA070222: "	"unprognostic (3.06e-2)"	"unprognostic (2.98e-2)"	"unprognostic (7.01e-2)"	"unprognostic (3.08e-3)"	"unprognostic (3.49e-3)"	"unprognostic (3.87e-1)"	"prognostic unfavorable (2.32e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.25e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.88e-3)"	"unprognostic (9.85e-2)"	"unprognostic (2.81e-1)"	"unprognostic (1.85e-1)"	"unprognostic (1.80e-1)"	"unprognostic (1.58e-2)"	"unprognostic (1.38e-1)"
JUNB		ENSG00000171223	"JunB proto-oncogene, AP-1 transcription factor subunit"	P17275	19	12791486-12793315	"Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 679.4"	"Group enriched"	"Detected in all"	5	"granulocytes: 679.4;monocytes: 182.7"	"Low cancer specificity"	"Detected in all"			"Heart muscle - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004464, HPA019149"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 11: Non-specific - Transcription"	Nucleoplasm		"CAB004464: AB_2130023, HPA019149: AB_1852053"	"unprognostic (1.03e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.11e-1)"	"unprognostic (1.04e-1)"	"unprognostic (7.17e-2)"	"unprognostic (1.77e-2)"	"unprognostic (2.19e-1)"	"unprognostic (2.13e-2)"	"unprognostic (1.12e-1)"	"prognostic unfavorable (3.65e-4)"	"unprognostic (1.79e-1)"	"unprognostic (9.78e-2)"	"prognostic unfavorable (1.05e-4)"	"unprognostic (7.20e-2)"	"unprognostic (7.06e-2)"	"unprognostic (3.77e-1)"	"unprognostic (1.02e-1)"
KRAS	"KRAS1, KRAS2"	ENSG00000133703	"KRAS proto-oncogene, GTPase"	P01116	12	25205246-25250936	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, Intellectual disability, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in all"		"Bile duct cancer: 233.0"		"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA049830	Approved					NA	NA		3300000	"Cluster 18: Basophils - Vesicular transport"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 19: Stomach & Colon cancer - Absorption"	"Cluster 12: Non-specific - Chromatin organization"			"HPA049830: AB_2680903"	"unprognostic (2.24e-2)"	"unprognostic (2.16e-2)"	"unprognostic (4.86e-3)"	"unprognostic (1.08e-2)"	"unprognostic (7.39e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.47e-2)"	"unprognostic (3.74e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.39e-1)"	"prognostic unfavorable (3.59e-4)"	"unprognostic (6.42e-2)"	"prognostic favorable (2.75e-5)"	"unprognostic (1.95e-2)"	"unprognostic (2.37e-1)"	"unprognostic (2.81e-2)"	"unprognostic (9.97e-2)"
MITF	"bHLHe32, MI, WS2, WS2A"	ENSG00000187098	"Melanocyte inducing transcription factor"	O75030	3	69739464-69968336	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Albinism, Cancer-related genes, Deafness, Disease variant, Microphthalmia, Osteopetrosis, Waardenburg syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 137.5;Melanocytes: 837.7;Oligodendrocyte precursor cells: 159.8;Oligodendrocytes: 226.9"	"Cancer enriched"	"Detected in all"	4	"melanoma: 39.2"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"basophil: 5.2;classical monocyte: 9.4;intermediate monocyte: 3.3;myeloid DC: 6.1;non-classical monocyte: 5.9"	"Group enriched"	"Detected in many"	6	"dendritic cells: 6.1;granulocytes: 5.2;monocytes: 9.4"	"Cancer enriched"	"Detected in all"	6	"skin cancer: 126.0"	"Breast - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002578, HPA003259"	Enhanced					NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 16: Skin cancer - Melanocyte processes"	"Cluster 25: Schwann cells & Melanocytes - Mixed function"			"CAB002578: AB_564111, HPA003259: AB_1079381"	"unprognostic (3.29e-1)"	"unprognostic (4.26e-2)"	"unprognostic (2.98e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.03e-1)"	"unprognostic (3.25e-1)"	"unprognostic (1.04e-2)"	"unprognostic (1.09e-1)"	"unprognostic (2.75e-1)"	"unprognostic (5.31e-3)"	"unprognostic (3.87e-3)"	"unprognostic (1.94e-1)"	"prognostic favorable (8.35e-10)"	"unprognostic (6.37e-2)"	"unprognostic (1.08e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.73e-1)"
MYC	"bHLHe39, c-Myc, MYCC"	ENSG00000136997	"MYC proto-oncogene, bHLH transcription factor"	P01106	8	127735434-127742951	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 254.6;skin 1: 289.1"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 608.5;Basal squamous epithelial cells: 1003.2;Squamous epithelial cells: 684.3;Suprabasal keratinocytes: 640.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000084, CAB010307, HPA055893, HPA066556"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 22: Squamous epithelial cells - Keratinization"	Nucleoplasm		"CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691"	"unprognostic (1.45e-2)"	"unprognostic (4.00e-3)"	"unprognostic (3.94e-3)"	"unprognostic (2.41e-3)"	"unprognostic (8.14e-2)"	"unprognostic (3.36e-3)"	"unprognostic (5.80e-2)"	"unprognostic (4.94e-3)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (7.52e-4)"	"unprognostic (5.19e-3)"	"unprognostic (9.86e-3)"	"prognostic unfavorable (5.49e-8)"	"unprognostic (7.85e-2)"	"unprognostic (4.66e-2)"	"unprognostic (2.48e-1)"	"prognostic unfavorable (4.96e-5)"
NAV3	"KIAA0938, POMFIL1"	ENSG00000067798	"Neuron navigator 3"	Q8IVL0	12	77324641-78213010	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 17.3;ovary: 18.3"	"Group enriched"	"Detected in many"	6	"Astrocytes: 854.7;Excitatory neurons: 1451.5;Inhibitory neurons: 738.0;Microglial cells: 519.9;Oligodendrocyte precursor cells: 752.8"	"Low cancer specificity"	"Detected in many"			"Group enriched"	"Detected in many"	8	"amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3"	"Immune cell enhanced"	"Detected in single"		"neutrophil: 1.0"	"Lineage enriched"	"Detected in single"	9	"granulocytes: 1.0"	"Cancer enhanced"	"Detected in many"		"Rhabdoid: 21.6"	"Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA032111, HPA061392"	Approved		Approved	"Nuclear membrane,Cytosol"		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 10: Brain - Neuronal signaling"	"Cluster 22: Rhabdoid cancers - Neuronal signaling"	"Cluster 38: Neurons - Neuronal signaling"	"Nuclear membrane"	Cytosol	"HPA032111: AB_10603881, HPA061392: "	"unprognostic (3.51e-1)"	"unprognostic (6.72e-2)"	"unprognostic (1.09e-2)"	"unprognostic (1.79e-1)"	"unprognostic (8.98e-2)"	"unprognostic (2.14e-1)"	"unprognostic (2.78e-1)"	"unprognostic (3.25e-2)"	"unprognostic (3.03e-2)"	"unprognostic (2.06e-2)"	"unprognostic (2.99e-1)"	"unprognostic (1.90e-1)"	"unprognostic (5.68e-7)"	"unprognostic (6.86e-3)"	"unprognostic (1.23e-1)"	"unprognostic (1.58e-2)"	"unprognostic (2.29e-3)"
NRAS	N-ras	ENSG00000213281	"NRAS proto-oncogene, GTPase"	P01111	1	114704469-114716771	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010157, HPA049830, CAB079912"	Uncertain		Supported	"Plasma membrane"		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 74: Pancreatic cells - Mixed function"	"Plasma membrane"		"CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903"	"unprognostic (4.75e-2)"	"unprognostic (2.81e-1)"	"unprognostic (1.09e-3)"	"unprognostic (2.11e-2)"	"unprognostic (8.59e-3)"	"unprognostic (1.14e-1)"	"prognostic unfavorable (3.03e-7)"	"unprognostic (7.76e-3)"	"unprognostic (1.57e-2)"	"unprognostic (1.01e-3)"	"prognostic unfavorable (1.36e-4)"	"unprognostic (6.60e-3)"	"prognostic unfavorable (7.87e-4)"	"unprognostic (2.68e-1)"	"unprognostic (1.30e-1)"	"unprognostic (1.16e-1)"	"unprognostic (3.33e-2)"
PTCH1	"BCNS, NBCCS, PTCH"	ENSG00000185920	"Patched 1"	Q13635	9	95442980-95517057	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		Receptor	"Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 26.7"	"Cell type enhanced"	"Detected in many"		"Late spermatids: 260.1;Leydig cells: 186.5;Peritubular cells: 426.5;Theca cells: 103.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"gdT-cell: 6.1"	"Lineage enriched"	"Detected in single"	9	"T-cells: 6.1"	"Low cancer specificity"	"Detected in all"			"Testis - Peritubular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013717, HPA075072"	Uncertain		Approved	"Golgi apparatus"		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 52: Endometrial stromal cells - ECM organization"	"Golgi apparatus"		"CAB013717: , HPA075072: AB_2686733"	"unprognostic (1.46e-1)"	"unprognostic (1.06e-1)"	"unprognostic (3.16e-1)"	"unprognostic (1.79e-2)"	"unprognostic (3.22e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.54e-3)"	"unprognostic (2.63e-1)"	"unprognostic (8.66e-3)"	"unprognostic (1.52e-2)"	"unprognostic (2.82e-1)"	"unprognostic (1.13e-6)"	"unprognostic (8.63e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.76e-1)"	"unprognostic (2.82e-1)"
PTEN	"BZS, MHAM, MMAC1, PTEN1, TEP1"	ENSG00000171862	"Phosphatase and tensin homolog"	P60484	10	87863625-87971930	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Lipid metabolism, Neurogenesis"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 60.5"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in many"			"Breast - Adipocytes (Breast), Prostate - Fibroblasts, Testis - Early spermatids"	"Low region specificity"	"Detected in all"							"CAB004076, HPA031335, CAB080153, CAB080155, CAB080157"	Approved		Supported	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 67: Non-specific - Mitochondria & RNA binding"	"Cluster 72: Smooth muscle cells - ECM organization"	Cytosol	Nucleoplasm	"CAB004076: AB_390810, CAB080153: , CAB080155: , CAB080157: , HPA031335: AB_2797221"	"unprognostic (8.72e-2)"	"unprognostic (2.45e-1)"	"unprognostic (5.43e-1)"	"unprognostic (1.50e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.07e-1)"	"unprognostic (6.87e-2)"	"unprognostic (9.77e-2)"	"unprognostic (2.71e-1)"	"prognostic unfavorable (7.35e-4)"	"unprognostic (1.57e-1)"	"unprognostic (2.73e-1)"	"unprognostic (6.54e-3)"	"unprognostic (2.41e-1)"
SHH	"HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS"	ENSG00000164690	"Sonic hedgehog signaling molecule"	Q15465	7	155799980-155812463	"Disease related genes, Human disease related genes, Predicted intracellular proteins"		"Developmental protein, Hydrolase, Protease"	"Disease variant, Holoprosencephaly, Microphthalmia"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 13.6;stomach 1: 10.5;urinary bladder: 16.2"	"Cell type enhanced"	"Detected in some"		"Alveolar cells type 1: 10.9;Alveolar cells type 2: 9.4;Cholangiocytes: 15.4;Collecting duct cells: 7.9;Gastric mucus-secreting cells: 10.1;Glandular and luminal cells: 8.4;Hepatocytes: 17.9"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"								"Intracellular and membrane"	NA	NA		5500000		"Cluster 85: Liver - Metabolism"	"Cluster 2: DU4475 - Unknown function"	"Cluster 14: Endometrium - Transcription regulation"				"unprognostic (7.17e-2)"	"unprognostic (7.68e-3)"	"unprognostic (6.70e-2)"	"prognostic favorable (8.62e-5)"	"unprognostic (1.59e-1)"	"unprognostic (2.50e-2)"	"unprognostic (2.39e-3)"	"unprognostic (1.82e-2)"	"unprognostic (1.83e-1)"	"unprognostic (2.16e-2)"	"unprognostic (3.47e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.77e-3)"	"unprognostic (2.86e-1)"	"unprognostic (2.85e-1)"	"unprognostic (3.43e-2)"	"unprognostic (2.66e-2)"
SMO	"FZD11, SMOH"	ENSG00000128602	"Smoothened, frizzled class receptor"	Q99835	7	129188633-129213545	"Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters"		"Developmental protein, G-protein coupled receptor, Receptor, Transducer"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 26.6;Leydig cells: 20.3;Muller glia cells: 14.0;Peritubular cells: 22.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Lung - Fibroblast_2, Stomach - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB011446	Approved					NA	NA				"Cluster 15: Liver - Metabolism"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 52: Endometrial stromal cells - ECM organization"			"CAB011446: "	"unprognostic (2.48e-2)"	"unprognostic (2.69e-2)"	"unprognostic (7.09e-2)"	"unprognostic (1.10e-1)"	"unprognostic (8.16e-2)"	"unprognostic (2.02e-1)"	"unprognostic (3.63e-1)"	"unprognostic (5.89e-2)"	"unprognostic (5.38e-3)"	"unprognostic (1.59e-1)"	"unprognostic (1.17e-2)"	"unprognostic (8.74e-3)"	"unprognostic (1.62e-1)"	"unprognostic (5.15e-3)"	"unprognostic (2.09e-1)"	"unprognostic (2.25e-1)"	"unprognostic (2.61e-2)"
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687538	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876"	Enhanced		Enhanced	Nucleoplasm,Vesicles,Cytosol		Yes	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 49: Non-specific - Unknown function"	"Cluster 39: Non-specific - Translation"	Nucleoplasm	"Vesicles, Cytosol"	"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, HPA051244: AB_2681403, HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favorable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavorable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"