Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Calmodulin-binding, Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 366.7;Late spermatids: 1337.4;Proximal enterocytes: 1054.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.0" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Fibroblast_1, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 59: Proximal enterocytes - Transmembrane transport" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" ACTN4 FSGS1 ENSG00000130402 "Actinin alpha 4" O43707 19 38647649-38731589 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 614.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001873, HPA006035" Supported Approved "Actin filaments,Cytosol" NA NA 71000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 72: Smooth muscle cells - ECM organization" "Actin filaments" Cytosol "HPA001873: AB_1078096, HPA006035: AB_1078095" "unprognostic (1.03e-1)" "unprognostic (6.34e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-2)" "unprognostic (2.37e-1)" "unprognostic (3.34e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (1.70e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.99e-1)" "prognostic favorable (5.25e-5)" "unprognostic (6.59e-2)" "unprognostic (1.91e-1)" "unprognostic (6.75e-3)" "unprognostic (6.52e-2)" ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 6 "Early spermatids: 193.4;Oligodendrocytes: 416.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 45: Non-specific - Cell proliferation" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 220.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 108.5;Endometrial ciliated cells: 115.5;Glandular and luminal cells: 222.6;Hepatocytes: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 337.3" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "HPA018885, CAB056156" Supported "Secreted to blood" NA NA 1640000000 9200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" AQP2 ENSG00000167580 "Aquaporin 2" P41181 12 49950737-49958878 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 92 "kidney: 386.9;seminal vesicle: 212.4" "Cell type enriched" "Detected in some" 17 "Collecting duct cells: 3264.7" "Group enriched" "Detected in some" 6 "renal cancer: 1.7;stomach cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.3" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA046834 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 70: Basal prostatic cells - Lipid metabolism" "HPA046834: AB_2679830" "unprognostic (2.10e-1)" "unprognostic (3.77e-2)" "unprognostic (6.96e-3)" "unprognostic (4.48e-3)" "unprognostic (3.60e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (7.38e-3)" "unprognostic (5.92e-2)" "unprognostic (4.60e-2)" "unprognostic (2.01e-2)" "unprognostic (1.11e-1)" ARHGDIA "GDIA1, RHOGDI" ENSG00000141522 "Rho GDP dissociation inhibitor alpha" P52565 17 81867721-81871378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010005, HPA021407" Approved Supported Cytosol NA NA 21000000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 65: Breast cancer - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" Cytosol "CAB010005: AB_2227516, HPA021407: AB_1856267" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" "unprognostic (5.00e-2)" "unprognostic (8.39e-3)" "unprognostic (1.39e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (5.32e-2)" "unprognostic (4.67e-2)" "unprognostic (2.67e-2)" "unprognostic (6.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (3.29e-1)" "unprognostic (6.88e-3)" ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "kidney: 63.6;salivary gland: 78.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 19.7;Cytotrophoblasts: 13.6;Distal tubular cells: 18.7;Ionocytes: 11.6;Melanocytes: 8.7;Salivary duct cells: 24.8;Serous glandular cells: 11.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 9.9;Gastric cancer: 11.2" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018029, HPA064555" Enhanced Uncertain Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" Cytosol "HPA018029: AB_1845190, HPA064555: AB_2685284" "unprognostic (1.99e-2)" "unprognostic (8.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (6.53e-2)" "unprognostic (4.63e-2)" "unprognostic (4.28e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-3)" "unprognostic (1.73e-1)" "prognostic favorable (1.32e-6)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-2)" ATP6V1B1 "ATP6B1, RTA1B, VATB, Vma2, VPP3" ENSG00000116039 "ATPase H+ transporting V1 subunit B1" P15313 2 70935900-70965431 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 127.4;salivary gland: 139.8" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 29.3;Distal tubular cells: 80.9" "Group enriched" "Detected in many" 5 "ovarian cancer: 94.7;renal cancer: 23.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 16.3;ovarian cancer: 12.8" "Kidney - Intercalated cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009523, HPA031847" Enhanced Approved "Nucleoplasm,Nuclear membrane" No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 28: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear membrane" "CAB009523: AB_677577, HPA031847: AB_2674072" "unprognostic (2.28e-2)" "unprognostic (6.02e-2)" "unprognostic (2.20e-5)" "unprognostic (1.15e-2)" "unprognostic (3.96e-1)" "unprognostic (1.31e-1)" "unprognostic (2.22e-2)" "unprognostic (2.17e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (2.94e-2)" "unprognostic (1.40e-1)" "unprognostic (1.33e-3)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (3.63e-5)" "unprognostic (1.97e-2)" AVIL "ADVIL, DOC6, FLJ12386, p92" ENSG00000135407 Advillin O75366 12 57797376-57818704 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 9.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.0;Gastric mucus-secreting cells: 26.2;Rod photoreceptor cells: 25.5;Skeletal myocytes: 22.8" "Cancer enriched" "Detected in all" 5 "glioma: 9.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.0" "Cancer enhanced" "Detected in many" "lung cancer: 8.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA058864 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 56: Neurons - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "HPA058864: AB_2683838" "unprognostic (3.86e-2)" "unprognostic (9.86e-3)" "unprognostic (4.36e-2)" "unprognostic (3.38e-3)" "unprognostic (1.36e-1)" "unprognostic (7.79e-4)" "unprognostic (1.42e-1)" "unprognostic (7.44e-2)" "unprognostic (9.13e-2)" "unprognostic (8.02e-2)" "unprognostic (1.04e-2)" "unprognostic (1.07e-2)" "unprognostic (2.57e-4)" "unprognostic (2.44e-1)" "unprognostic (9.41e-2)" "unprognostic (3.29e-1)" "prognostic favorable (2.71e-4)" AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.1" "Group enriched" "Detected in some" 32 "Adipocytes: 46.6;Collecting duct cells: 41.4;Endothelial cells: 18.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 7 "cerebellum: 3.9" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.6;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 29 "monocytes: 3.6" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 6.8" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: DU4475 - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (3.05e-2)" "unprognostic (5.62e-2)" "unprognostic (1.99e-4)" "unprognostic (2.50e-4)" "unprognostic (2.76e-1)" "unprognostic (7.10e-6)" "unprognostic (3.80e-3)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "unprognostic (4.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (4.38e-1)" "unprognostic (9.83e-2)" CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2670.7;Erythroid cells: 1674.5;Gastric mucus-secreting cells: 1248.4;Muller glia cells: 1263.5;Paneth cells: 644.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 50: Enterocytes - Absorption" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" CD151 "PETA-3, RAPH, SFA-1, TSPAN24" ENSG00000177697 "CD151 molecule (Raph blood group)" P48509 11 832887-839831 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Blood group antigen" "Deafness, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 667.2;Exocrine glandular cells: 860.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002428, HPA011906" Supported NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 74: Pancreatic cells - Mixed function" "CAB002428: AB_564129, HPA011906: AB_1846245" "unprognostic (1.50e-1)" "unprognostic (1.12e-2)" "unprognostic (5.47e-2)" "unprognostic (5.45e-3)" "unprognostic (4.10e-3)" "unprognostic (2.45e-2)" "prognostic unfavorable (5.58e-4)" "prognostic unfavorable (9.46e-4)" "unprognostic (5.47e-2)" "unprognostic (2.41e-1)" "unprognostic (1.02e-3)" "unprognostic (3.31e-1)" "unprognostic (4.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.24e-1)" "prognostic favorable (6.92e-4)" "unprognostic (7.83e-2)" CD2AP CMS ENSG00000198087 "CD2 associated protein" Q9Y5K6 6 47477789-47627263 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003267, HPA003326, CAB004352" Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 58000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "Plasma membrane" "Centriolar satellite" "CAB004352: AB_627009, HPA003267: AB_1078458, HPA003326: AB_1078457" "unprognostic (5.98e-2)" "unprognostic (1.08e-2)" "unprognostic (1.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.31e-1)" "unprognostic (1.77e-2)" "unprognostic (1.74e-3)" "unprognostic (1.19e-1)" "unprognostic (6.71e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (2.21e-1)" "unprognostic (3.09e-3)" "unprognostic (6.12e-3)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "prognostic favorable (7.57e-5)" CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 361.6;Hepatocytes: 844.7;Leydig cells: 290.7;Thymic epithelial cells: 395.1" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 78.4" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 65: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" CFHR5 "CFHL5, FHR-5, FHR5" ENSG00000134389 "Complement factor H related 5" Q9BXR6 1 196977556-197009678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1675 "liver: 167.5" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 96.2" "Cancer enriched" "Detected in single" 396 "liver cancer: 57.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "HPA038915, HPA040726" Supported "Secreted to blood" NA NA 1900000000 "Cluster 62: Liver - Hemostasis" "Cluster 61: Liver - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "HPA038915: AB_2676269, HPA040726: AB_2677101" "unprognostic (9.12e-3)" CLCN5 "ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN" ENSG00000171365 "Chloride voltage-gated channel 5" P51795 X 49922596-50099235 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 23.7;kidney: 46.2;liver: 16.9" "Cell type enhanced" "Detected in many" "dendritic cells: 49.9;Microglial cells: 45.6" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000401, HPA003213" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 11: Non-specific - Transcription" "Golgi apparatus, Plasma membrane" Cytosol "HPA000401: AB_1078531, HPA003213: AB_2666843" "unprognostic (3.33e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.57e-1)" "unprognostic (7.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.20e-4)" "unprognostic (3.59e-2)" "prognostic favorable (2.05e-8)" "unprognostic (7.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" COL4A3 ENSG00000169031 "Collagen type IV alpha 3 chain" Q01955 2 227164624-227314792 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 52.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 53.3;Bipolar cells: 68.8;Collecting duct cells: 45.3;Cone photoreceptor cells: 193.0;Muller glia cells: 112.5;Oligodendrocyte precursor cells: 81.3;Skeletal myocytes: 65.3" "Group enriched" "Detected in some" 6 "lung cancer: 1.7;renal cancer: 3.0;thyroid cancer: 5.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 7 "B-cells: 1.0" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9;Myeloma: 7.5" "Lung - Alveolar cells type 1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042064 Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 68: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA042064: AB_10794410" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-6)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (1.84e-2)" "unprognostic (7.07e-3)" "unprognostic (2.30e-1)" "unprognostic (9.09e-3)" "unprognostic (9.30e-2)" "unprognostic (3.02e-2)" "prognostic favorable (2.51e-7)" "unprognostic (1.78e-1)" "unprognostic (3.10e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 104.3;Collecting duct cells: 41.4;Cone photoreceptor cells: 43.1;Granulosa cells: 60.8;Muller glia cells: 73.9;Oligodendrocyte precursor cells: 52.9;Skeletal myocytes: 54.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 4.1" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cancer enhanced" "Detected in many" "cervical cancer: 12.5;ovarian cancer: 9.2" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Enzymes" "Cluster 17: Granulosa cells - Transcription regulation" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" COQ8B "ADCK4, COQ8, FLJ12229" ENSG00000123815 "Coenzyme Q8B" Q96D53 19 40691514-40725784 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027229, HPA027277, HPA027279, HPA028303" Supported Enhanced Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 56: Ciliated cells - Cilium assembly" Mitochondria "HPA027229: AB_10600100, HPA027277: AB_10599857, HPA027279: AB_10601219, HPA028303: AB_2672551" "unprognostic (7.57e-2)" "unprognostic (9.48e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-2)" "unprognostic (2.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.85e-1)" "unprognostic (2.27e-1)" "unprognostic (2.82e-2)" "unprognostic (1.48e-1)" "unprognostic (2.93e-2)" "unprognostic (6.18e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (2.65e-2)" CRB2 "FLJ16786, FLJ38464" ENSG00000148204 "Crumbs cell polarity complex component 2" Q5IJ48 9 123356170-123380324 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Gastrulation, Sensory transduction, Vision" "Developmental protein" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.9;choroid plexus: 14.1;retina: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 39.2;Bipolar cells: 37.4;Cone photoreceptor cells: 63.8;Oligodendrocytes: 25.4;Rod photoreceptor cells: 108.8;Thymic epithelial cells: 27.9" "Group enriched" "Detected in some" 7 "glioma: 9.4;ovarian cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.2" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043674 Approved Supported "Intracellular and membrane" NA NA 210000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 44: Photoreceptor cells - Visual perception" "HPA043674: AB_10962974" "unprognostic (1.38e-2)" "unprognostic (2.39e-2)" "unprognostic (1.26e-1)" "unprognostic (2.83e-4)" "unprognostic (2.85e-2)" "unprognostic (1.14e-2)" "unprognostic (2.31e-1)" "unprognostic (3.69e-4)" "unprognostic (1.20e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-3)" "unprognostic (3.09e-1)" "unprognostic (5.56e-5)" "unprognostic (1.31e-1)" "unprognostic (1.55e-1)" "unprognostic (4.38e-2)" "unprognostic (3.38e-1)" CUL3 ENSG00000036257 "Cullin 3" Q13618 2 224470150-224585397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, ER-Golgi transport, Mitosis, Transport, Ubl conjugation pathway" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 224.8" "Cell type enhanced" "Detected in all" "Early spermatids: 214.3;Late spermatids: 306.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002678 Supported NA NA 65000 "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 1: T-cells - Immune response" "CAB002678: " "unprognostic (1.22e-2)" "unprognostic (2.35e-1)" "unprognostic (7.05e-2)" "unprognostic (6.29e-2)" "unprognostic (2.82e-1)" "unprognostic (7.03e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-3)" "unprognostic (2.65e-2)" "unprognostic (1.01e-2)" "unprognostic (6.16e-2)" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (8.74e-3)" "unprognostic (9.61e-2)" "unprognostic (1.87e-2)" DGKE "DAGK6, DGK" ENSG00000153933 "Diacylglycerol kinase epsilon" P52429 17 56834107-56869567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Kinase, Transferase" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 34.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 170.4;Cone photoreceptor cells: 153.4;Inhibitory neurons: 88.0;Rod photoreceptor cells: 168.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017167 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: Myeloma - Humoral immune response" "Cluster 35: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA017167: AB_1847638" "unprognostic (1.19e-2)" "unprognostic (2.11e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.92e-5)" "unprognostic (4.20e-2)" "unprognostic (4.87e-2)" "unprognostic (3.37e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-3)" "unprognostic (4.75e-2)" "unprognostic (6.07e-3)" "unprognostic (2.68e-1)" "unprognostic (2.55e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-1)" "unprognostic (3.69e-3)" EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 230.6" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 1: 3455.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (other), Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 42: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 39: Non-specific - Unknown function" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm Cytosol "HPA014711: AB_1848147, HPA070816: " "unprognostic (1.75e-1)" "unprognostic (4.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (9.27e-2)" "unprognostic (8.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (2.85e-8)" "unprognostic (9.54e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (9.52e-2)" FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 3183.4;Fibroblasts: 713.4;Hepatocytes: 809.9;Pancreatic endocrine cells: 523.8;Smooth muscle cells: 552.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 4649.5;thyroid cancer: 4327.2" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 227000000000000 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" HNF1B "HNF1beta, LFB3, MODY5, TCF2, VHNF1" ENSG00000275410 "HNF1 homeobox B" P35680 17 37686431-37745105 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 61.1;pancreas: 33.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 86.6;Collecting duct cells: 47.3;Ductal cells: 42.4;Early spermatids: 36.4;Exocrine glandular cells: 30.5;Glandular and luminal cells: 41.1;Proximal tubular cells: 37.1" "Cancer enhanced" "Detected in many" "renal cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 44.7" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in single" "HPA002083, CAB068192" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm Vesicles "CAB068192: AB_2665649, HPA002083: AB_1080232" "unprognostic (2.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (5.29e-3)" "unprognostic (5.29e-2)" "unprognostic (3.00e-2)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "prognostic favorable (6.00e-4)" "unprognostic (7.06e-2)" "unprognostic (2.26e-1)" "unprognostic (7.49e-2)" "prognostic favorable (2.51e-6)" HPSE2 "HPA2, HPR2, UFS" ENSG00000172987 "Heparanase 2 (inactive)" Q8WWQ2 10 98457077-99235862 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.6;cervix: 36.7;vagina: 27.6" "Cell type enriched" "Detected in some" 9 "Astrocytes: 872.7" "Cancer enhanced" "Detected in some" "prostate cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Leukemia: 7.0;prostate cancer: 2.4" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044603 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA044603: AB_10794051" "unprognostic (2.44e-1)" "unprognostic (4.28e-3)" "unprognostic (4.83e-3)" "unprognostic (6.00e-2)" "unprognostic (1.15e-1)" "unprognostic (1.59e-1)" "unprognostic (3.05e-2)" "unprognostic (1.82e-2)" "unprognostic (4.03e-2)" "unprognostic (7.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-4)" "unprognostic (5.79e-2)" "unprognostic (2.51e-1)" "unprognostic (9.39e-3)" "unprognostic (6.13e-3)" INF2 "C14orf151, C14orf173, MGC13251" ENSG00000203485 "Inverted formin 2" Q27J81 14 104681146-104722535 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 137.8;Gastric mucus-secreting cells: 179.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Testis - Sertoli cells" "Region enhanced" "Detected in all" "basal ganglia: 224.1" "Low region specificity" "Detected in all" HPA000724 Approved Approved "Nuclear bodies,Endoplasmic reticulum" NA NA 3000000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 46: Non-specific - Unknown function" "Cluster 50: Enterocytes - Absorption" "Endoplasmic reticulum" "Nuclear bodies" "HPA000724: AB_1078325" "unprognostic (1.42e-1)" "unprognostic (9.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.00e-2)" "unprognostic (1.49e-2)" "unprognostic (5.90e-3)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.13e-2)" "unprognostic (9.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.26e-2)" "unprognostic (1.36e-3)" "unprognostic (7.24e-2)" "unprognostic (4.01e-1)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.70e-2)" KANK2 "ANKRD25, KIAA1518, MXRA3" ENSG00000197256 "KN motif and ankyrin repeat domains 2" Q63ZY3 19 11164270-11197791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 192.7;Endometrial stromal cells: 152.2;Leydig cells: 127.3;Peritubular cells: 219.1;Smooth muscle cells: 141.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015643 Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm Cytosol "HPA015643: AB_1844839" "unprognostic (2.37e-1)" "unprognostic (8.03e-2)" "unprognostic (1.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (3.23e-3)" "unprognostic (1.54e-1)" "unprognostic (8.63e-2)" "unprognostic (8.98e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (8.73e-5)" "unprognostic (4.01e-2)" "unprognostic (1.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" KLHL3 KIAA1129 ENSG00000146021 "Kelch like family member 3" Q9UH77 5 137617500-137736089 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.2;Excitatory neurons: 90.5;Inhibitory neurons: 54.8;Late spermatids: 73.3;Muller glia cells: 39.8;Oligodendrocytes: 62.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Intercalated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051291 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "HPA051291: AB_2681423" "unprognostic (4.31e-2)" "unprognostic (5.31e-1)" "unprognostic (4.99e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (6.17e-2)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.41e-1)" "unprognostic (6.39e-3)" "unprognostic (3.28e-1)" "unprognostic (9.32e-2)" "unprognostic (1.76e-1)" "unprognostic (1.71e-1)" "unprognostic (5.20e-3)" "unprognostic (1.50e-4)" LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 156.0;Leydig cells: 143.8;Peritubular cells: 141.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 25000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Vesicles Cytosol "CAB000053: AB_2313665, CAB078160: AB_2665799, HPA001895: AB_1079227, HPA050033: " "unprognostic (1.12e-2)" "unprognostic (4.40e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" "unprognostic (4.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.59e-2)" "unprognostic (6.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.20e-2)" "unprognostic (1.24e-2)" LRIG2 KIAA0806 ENSG00000198799 "Leucine rich repeats and immunoglobulin like domains 2" O94898 1 113073198-113132260 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015538 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 2100000 "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 52: Spermatids - Smell perception" "Cluster 64: Non-specific - Transcription" "Golgi apparatus" Nucleoplasm "HPA015538: AB_2250170" "unprognostic (1.68e-2)" "unprognostic (1.13e-1)" "unprognostic (9.08e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (4.72e-2)" "unprognostic (1.27e-3)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (3.27e-2)" "unprognostic (5.95e-2)" "unprognostic (1.03e-2)" "unprognostic (1.03e-2)" "unprognostic (1.27e-2)" "unprognostic (2.34e-1)" "unprognostic (8.83e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" MAGI2 "ACVRIP1, AIP1, ARIP1, KIAA0705, MAGI-2" ENSG00000187391 "Membrane associated guanylate kinase, WW and PDZ domain containing 2" Q86UL8 7 78017055-79453667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.1" "Group enriched" "Detected in many" 7 "Astrocytes: 1710.3;Excitatory neurons: 2422.2;Inhibitory neurons: 2385.9;Oligodendrocyte precursor cells: 1157.6;Oligodendrocytes: 3777.4" "Cancer enriched" "Detected in many" 5 "glioma: 7.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013650 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: Myeloma - Humoral immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "HPA013650: AB_1853501" "unprognostic (4.32e-2)" "unprognostic (2.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.70e-4)" "unprognostic (5.04e-2)" "unprognostic (3.33e-1)" "unprognostic (6.57e-2)" "unprognostic (1.03e-1)" "unprognostic (2.17e-1)" "unprognostic (8.80e-3)" "unprognostic (1.64e-2)" "unprognostic (5.06e-2)" "prognostic favorable (1.08e-4)" "unprognostic (4.34e-4)" "unprognostic (2.17e-1)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 973.8;Alveolar cells type 2: 1409.1;Exocrine glandular cells: 988.8;Gastric mucus-secreting cells: 578.9;Ionocytes: 454.7;Respiratory ciliated cells: 564.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Cancer enhanced" "Detected in all" "breast cancer: 158.7;pancreatic cancer: 182.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Mitotic cells (Colon), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855, CAB080102, CAB080103" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 46: Non-specific - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , CAB080102: , CAB080103: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" MYO1E "HuncM-IC, MGC104638, MYO1C" ENSG00000157483 "Myosin IE" Q12965 15 59132434-59372871 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 301.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 23.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003003, HPA023886" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 13000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 68: Kidney - Mixed function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" Cytosol "HPA003003: , HPA023886: AB_1854253" "unprognostic (7.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "prognostic favorable (4.19e-4)" "unprognostic (1.49e-1)" "unprognostic (3.59e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.57e-6)" "unprognostic (1.89e-1)" "unprognostic (5.38e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (2.41e-1)" "unprognostic (7.92e-2)" "unprognostic (7.31e-2)" "unprognostic (9.71e-2)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" NPHS1 "CNF, NPHN" ENSG00000161270 "NPHS1 adhesion molecule, nephrin" O60500 19 35825372-35869287 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Myogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 41.5;pancreas: 22.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 50.6;Collecting duct cells: 68.9;Early spermatids: 14.4;Endometrial ciliated cells: 13.2;Exocrine glandular cells: 16.5;Glandular and luminal cells: 22.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB035555 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 14: Endometrium - Transcription regulation" "CAB035555: " "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" "unprognostic (1.65e-1)" "unprognostic (2.39e-2)" "unprognostic (6.47e-3)" "unprognostic (2.25e-2)" "unprognostic (1.58e-1)" "unprognostic (1.69e-1)" "unprognostic (3.32e-2)" "unprognostic (3.17e-1)" "unprognostic (3.83e-5)" "unprognostic (4.30e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" NPHS2 "PDCN, SRN1" ENSG00000116218 "NPHS2 stomatin family member, podocin" Q9NP85 1 179550539-179575952 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 140 "kidney: 255.0" "Cell type enriched" "Detected in some" 5 "Collecting duct cells: 35.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB037267, HPA049486" Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: BEWO - Unknown function" "Cluster 24: Spermatids - Unknown function" "CAB037267: AB_261982, HPA049486: AB_2680788" "unprognostic (6.77e-2)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" NR3C2 "MLR, MR" ENSG00000151623 "Nuclear receptor subfamily 3 group C member 2" P08235 4 148078762-148444698 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 257.5;Excitatory neurons: 271.9;Inhibitory neurons: 263.6;Microglial cells: 171.5;Oligodendrocyte precursor cells: 220.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.8" "Lineage enriched" "Detected in single" 6 "T-cells: 1.8" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009155, HPA074979" Enhanced Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "CAB009155: AB_2155949, HPA074979: AB_2686724" "unprognostic (2.75e-3)" "unprognostic (2.63e-2)" "unprognostic (6.70e-3)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (7.82e-3)" "unprognostic (1.04e-2)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (4.35e-2)" "unprognostic (4.97e-2)" "unprognostic (2.39e-1)" "prognostic favorable (3.10e-11)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" NUP107 NUP84 ENSG00000111581 "Nucleoporin 107" P57740 12 68686951-68745809 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031679 Uncertain "Nucleoplasm,Nuclear membrane,Centrosome" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" Nucleoplasm "Nuclear membrane, Centrosome" "HPA031679: AB_2673992" "unprognostic (2.89e-1)" "unprognostic (3.32e-1)" "unprognostic (4.10e-1)" "unprognostic (5.43e-2)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "prognostic unfavorable (3.12e-9)" "unprognostic (4.03e-2)" "unprognostic (1.23e-2)" "unprognostic (2.28e-1)" "unprognostic (1.17e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (1.28e-6)" "unprognostic (3.43e-2)" "unprognostic (2.05e-1)" "unprognostic (1.00e-1)" "unprognostic (1.96e-1)" NUP133 FLJ10814 ENSG00000069248 "Nucleoporin 133" Q8WUM0 1 229440259-229508341 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059767 Approved Supported "Nuclear membrane" NA NA 6300 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: Non-specific - RNA binding" "Cluster 61: Non-specific - Transcription" "Nuclear membrane" "HPA059767: AB_2684123" "unprognostic (2.05e-2)" "unprognostic (3.54e-1)" "unprognostic (5.75e-3)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (1.17e-1)" "unprognostic (3.02e-2)" "unprognostic (2.20e-2)" "unprognostic (5.72e-2)" "unprognostic (2.21e-1)" "unprognostic (4.93e-2)" "unprognostic (3.48e-1)" "unprognostic (8.31e-2)" "unprognostic (2.22e-1)" "unprognostic (7.01e-2)" "unprognostic (4.26e-2)" "unprognostic (3.30e-2)" NUP160 "FLJ22583, KIAA0197" ENSG00000030066 "Nucleoporin 160" Q12769 11 47778087-47848555 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 15000 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 64: Non-specific - Transcription" "unprognostic (8.72e-2)" "unprognostic (1.11e-1)" "unprognostic (3.22e-2)" "unprognostic (2.87e-2)" "unprognostic (2.27e-1)" "unprognostic (3.23e-1)" "unprognostic (3.59e-3)" "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.94e-1)" "unprognostic (3.78e-2)" "unprognostic (3.14e-2)" "unprognostic (2.22e-2)" "unprognostic (1.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.82e-1)" "unprognostic (1.01e-1)" NUP205 "C7orf14, KIAA0225" ENSG00000155561 "Nucleoporin 205" Q92621 7 135557917-135648757 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 24000 "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "unprognostic (3.64e-2)" "unprognostic (2.13e-1)" "unprognostic (6.05e-2)" "unprognostic (3.66e-3)" "unprognostic (4.00e-1)" "unprognostic (2.96e-2)" "prognostic unfavorable (1.90e-7)" "unprognostic (2.33e-2)" "unprognostic (2.12e-2)" "unprognostic (3.27e-2)" "unprognostic (7.53e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-2)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-2)" NUP85 "FLJ12549, NUP75" ENSG00000125450 "Nucleoporin 85" Q9BW27 17 75205659-75235758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061910, HPA062595" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 65: Breast cancer - Unknown function" "Cluster 18: Non-specific - Mixed function" Nucleoplasm Cytosol "HPA061910: AB_2684634, HPA062595: AB_2684801" "unprognostic (2.30e-1)" "unprognostic (5.10e-2)" "unprognostic (5.12e-3)" "unprognostic (2.52e-3)" "unprognostic (2.25e-1)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.73e-7)" "unprognostic (3.46e-1)" "unprognostic (1.09e-2)" "unprognostic (9.93e-2)" "unprognostic (2.94e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (1.03e-3)" "unprognostic (2.16e-1)" "unprognostic (9.10e-3)" "unprognostic (2.11e-1)" NUP93 KIAA0095 ENSG00000102900 "Nucleoporin 93" Q8N1F7 16 56730118-56850286 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017937 Uncertain NA NA 38000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 18: Non-specific - Mixed function" "HPA017937: AB_1854726" "unprognostic (6.31e-2)" "unprognostic (3.22e-2)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (3.99e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.18e-2)" "unprognostic (9.35e-3)" "unprognostic (5.22e-2)" "unprognostic (4.55e-2)" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (3.71e-1)" "unprognostic (1.85e-1)" "unprognostic (9.68e-2)" "unprognostic (3.74e-2)" OCRL "Dent-2, OCRL1" ENSG00000122126 "OCRL inositol polyphosphate-5-phosphatase" Q01968 X 129539849-129592561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Lipid metabolism" Hydrolase "Cataract, Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.6" "Group enriched" "Detected in many" 8 "dendritic cells: 1.2;monocytes: 3.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012495 Approved Approved "Microtubules,Centriolar satellite,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 48: Non-specific - RNA binding" "Cluster 17: Granulosa cells - Transcription regulation" Cytosol "Microtubules, Centriolar satellite" "HPA012495: AB_1851804" "prognostic unfavorable (2.93e-5)" "unprognostic (3.17e-2)" "unprognostic (2.30e-1)" "unprognostic (6.34e-3)" "unprognostic (9.88e-2)" "unprognostic (1.35e-1)" "unprognostic (2.82e-2)" "unprognostic (2.68e-1)" "unprognostic (3.08e-3)" "unprognostic (2.56e-2)" "unprognostic (6.30e-3)" "unprognostic (1.74e-1)" "unprognostic (4.61e-3)" "unprognostic (4.10e-1)" "unprognostic (5.83e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" PAX2 ENSG00000075891 "Paired box 2" Q02962 10 100735396-100829944 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 29.6;kidney: 85.3" "Group enriched" "Detected in some" 4 "Collecting duct cells: 135.9;Endometrial ciliated cells: 116.8;Glandular and luminal cells: 234.5" "Group enriched" "Detected in some" 19 "endometrial cancer: 6.7;ovarian cancer: 7.0;renal cancer: 14.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Kidney cancer: 16.3;ovarian cancer: 7.4;Rhabdoid: 10.5;Uterine cancer: 8.1" "Group enriched" "Detected in some" 9 "cerebellum: 1.3;pons and medulla: 3.4" "Group enriched" "Detected in some" 7 "cerebellum: 3.6;medulla oblongata: 5.6;spinal cord: 4.9" "CAB013024, HPA047704, HPA070751" Enhanced Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm "CAB013024: AB_2533990, HPA047704: AB_2636861, HPA070751: AB_2686305" "unprognostic (3.98e-2)" "unprognostic (9.55e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (4.85e-2)" "unprognostic (5.54e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (1.24e-2)" "unprognostic (6.59e-2)" "unprognostic (9.18e-2)" "unprognostic (3.30e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-1)" "unprognostic (6.34e-2)" "unprognostic (8.26e-2)" PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 93993931-94332823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 67.4;Distal enterocytes: 79.8;Inhibitory neurons: 82.0;Muller glia cells: 71.3;Oligodendrocyte precursor cells: 117.9;Skeletal myocytes: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 37: Neurons - Neuronal signaling" Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.8;kidney: 36.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 190.8;Horizontal cells: 54.5;Inhibitory neurons: 224.7;Oligodendrocyte precursor cells: 121.3;Undifferentiated cells: 47.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "colorectal cancer: 9.3;Gastric cancer: 6.3" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 162.2" "Group enriched" "Detected in some" 4 "Club cells: 34.2;Late spermatids: 28.2;Smooth muscle cells: 11.5" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 15.0;colorectal cancer: 6.0" "Lung - Alveolar cells type 2, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA005131 Approved "Secreted to blood" NA NA 692000 10000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 53: Connective tissue cells - ECM organization" "HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;retina: 15.4" "Group enriched" "Detected in many" 24 "Excitatory neurons: 3385.3;Inhibitory neurons: 4585.4" "Cancer enhanced" "Detected in many" "glioma: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Podocytes, Lung - Fibroblast_1, Pancreas - Beta cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013371, HPA013975" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA 1900000 "Cluster 58: Brain - Synaptic function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA013371: AB_1856391, HPA013975: " "unprognostic (1.14e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.82e-2)" "unprognostic (5.93e-3)" "unprognostic (3.87e-1)" "unprognostic (2.83e-3)" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (2.90e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (9.65e-3)" SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 157.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 226.5;Alveolar cells type 2: 187.3;Distal enterocytes: 120.6;Glandular and luminal cells: 185.6;Intestinal goblet cells: 186.4;Salivary duct cells: 181.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 6.8" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA012743 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" SCNN1B ENaCbeta ENSG00000168447 "Sodium channel epithelial 1 subunit beta" P51168 16 23278231-23381294 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.8;intestine: 94.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 94.7;Club cells: 57.7;Distal enterocytes: 198.1;Ionocytes: 49.4;Salivary duct cells: 78.1;Suprabasal keratinocytes: 51.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 26.4" "Region enriched" "Detected in single" 9 "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 29.9;Sarcoma: 37.7" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 5 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA015612 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 27: TE 441.T - Unknown function" "Cluster 50: Enterocytes - Absorption" "HPA015612: AB_1856629" "unprognostic (7.45e-2)" "unprognostic (1.76e-3)" "unprognostic (1.39e-1)" "unprognostic (6.74e-3)" "unprognostic (1.74e-2)" "unprognostic (5.11e-3)" "unprognostic (7.74e-2)" "unprognostic (5.49e-3)" "unprognostic (2.60e-1)" "unprognostic (2.40e-1)" "unprognostic (3.68e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.32e-1)" "unprognostic (4.66e-2)" "unprognostic (3.93e-3)" "unprognostic (1.25e-2)" SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.0;Club cells: 26.4;Collecting duct cells: 41.4;Gastric mucus-secreting cells: 14.9;Glandular and luminal cells: 16.7;Ionocytes: 17.9;Salivary duct cells: 27.2" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bone cancer: 15.9" "Lung - Alveolar cells type 1, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 14: Bone cancer - Transcription" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" SEC61A1 ENSG00000058262 "SEC61 translocon subunit alpha 1" P61619 3 128051641-128071683 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 230.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022076 Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 40: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB022076: " "unprognostic (1.84e-1)" "unprognostic (8.00e-2)" "unprognostic (8.21e-2)" "prognostic favorable (7.82e-4)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (2.84e-2)" "unprognostic (4.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.85e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.84e-9)" "unprognostic (2.73e-2)" "unprognostic (3.18e-2)" "unprognostic (8.33e-2)" "unprognostic (2.51e-2)" SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815948-70881184 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 74: Pancreatic cells - Mixed function" "Endoplasmic reticulum" "HPA021125: AB_1856803, HPA023086: AB_1856804" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (7.60e-2)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (9.52e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "unprognostic (9.21e-2)" "unprognostic (4.68e-3)" SLC22A12 "OAT4L, RST, URAT1" ENSG00000197891 "Solute carrier family 22 member 12" Q96S37 11 64590641-64602353 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 204 "kidney: 109.4" "Cell type enriched" "Detected in some" 20 "Proximal tubular cells: 129.8" "Cancer enriched" "Detected in some" 4 "renal cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA024575 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "HPA024575: AB_1858650" "unprognostic (5.88e-2)" "unprognostic (2.33e-1)" "prognostic favorable (2.63e-4)" "unprognostic (6.19e-2)" "unprognostic (3.91e-2)" SLC26A1 "EDM4, SAT-1" ENSG00000145217 "Solute carrier family 26 member 1" Q9H2B4 4 979073-993440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 6.0;Excitatory neurons: 4.4;Hepatocytes: 9.5;Inhibitory neurons: 4.3;Oligodendrocyte precursor cells: 5.3;Proximal enterocytes: 6.7;Proximal tubular cells: 6.3" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 5.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.4" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA041654 Uncertain Approved Microtubules NA NA "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Microtubules "HPA041654: AB_10796350" "unprognostic (1.96e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-1)" "unprognostic (4.91e-2)" "unprognostic (1.74e-1)" "unprognostic (2.67e-4)" "unprognostic (5.13e-2)" "unprognostic (5.82e-2)" "unprognostic (2.16e-1)" "unprognostic (3.88e-2)" "unprognostic (1.53e-3)" "unprognostic (2.92e-2)" "prognostic favorable (1.19e-4)" "unprognostic (1.18e-2)" "unprognostic (2.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.65e-3)" SLC2A9 "Glut9, GLUTX, URATv1" ENSG00000109667 "Solute carrier family 2 member 9" Q9NRM0 4 9771153-10054936 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 29.3;liver: 21.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 49.4;Basal respiratory cells: 25.3;Proximal tubular cells: 73.7" "Cancer enhanced" "Detected in many" "renal cancer: 6.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 36.9;myeloid DC: 30.5" "Group enriched" "Detected in many" 30 "dendritic cells: 30.5;monocytes: 36.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 13.6;head and neck cancer: 12.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA066229, HPA075669" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 70: Basal prostatic cells - Lipid metabolism" "HPA066229: AB_2685639, HPA075669: " "unprognostic (3.21e-1)" "unprognostic (8.99e-3)" "unprognostic (1.25e-2)" "unprognostic (2.01e-1)" "unprognostic (2.14e-2)" "unprognostic (2.56e-2)" "unprognostic (8.94e-2)" "unprognostic (6.94e-2)" "unprognostic (2.86e-2)" "unprognostic (1.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.23e-1)" "prognostic favorable (1.32e-11)" "unprognostic (1.01e-1)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.20e-1)" SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "kidney: 155.4" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 102.3" "Cancer enriched" "Detected in single" 12 "renal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 60: Proximal tubular cells - Absorption" "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: AB_2681409, HPA077175: " "unprognostic (1.17e-1)" "unprognostic (3.33e-3)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (2.28e-1)" "unprognostic (4.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (5.95e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-2)" SLC36A2 "PAT2, TRAMD1, tramdorin" ENSG00000186335 "Solute carrier family 36 member 2" Q495M3 5 151314972-151347590 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 60 "kidney: 67.6;skeletal muscle: 80.2;tongue: 29.8" "Group enriched" "Detected in some" 6 "Proximal tubular cells: 42.9;Skeletal myocytes: 18.8" "Cancer enriched" "Detected in single" 9 "renal cancer: 0.5" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA044002, HPA062229" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: DU4475 - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" "HPA044002: AB_10964214, HPA062229: AB_2684717" "unprognostic (3.47e-1)" "unprognostic (3.40e-1)" "unprognostic (2.26e-2)" "unprognostic (6.23e-2)" "unprognostic (8.38e-3)" "unprognostic (4.66e-3)" "unprognostic (3.03e-1)" "unprognostic (7.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.92e-1)" "unprognostic (1.20e-3)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" "unprognostic (3.89e-2)" SLC4A1 "AE1, CD233, DI, EPB3, FR, RTA1A, SW, WD, WR" ENSG00000004939 "Solute carrier family 4 member 1 (Diego blood group)" P02730 17 44248390-44268141 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Blood group antigen" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "bone marrow: 407.2" "Cell type enriched" "Detected in some" 289 "Erythroid cells: 900.9" "Cancer enriched" "Detected in single" 91 "renal cancer: 16.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 3.0;neutrophil: 2.7" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 21 "Leukemia: 15.9" "Kidney - Intercalated cells, Liver - Erythroid cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015584, CAB034438, HPA063911" Enhanced NA NA 22000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "CAB034438: AB_2123479, HPA015584: AB_1844824, HPA063911: AB_2685151" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (3.36e-1)" "unprognostic (2.44e-2)" "unprognostic (2.32e-2)" "unprognostic (1.56e-2)" "unprognostic (1.55e-1)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (6.72e-3)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (1.93e-2)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (2.13e-1)" SLC4A4 "hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5" ENSG00000080493 "Solute carrier family 4 member 4" Q9Y6R1 4 71062667-71572087 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 119.5;pancreas: 260.3" "Cell type enhanced" "Detected in many" "Astrocytes: 793.6;Cholangiocytes: 142.4;Distal enterocytes: 234.7;Ductal cells: 143.7;Proximal tubular cells: 174.7" "Group enriched" "Detected in many" 5 "glioma: 23.9;pancreatic cancer: 22.5;prostate cancer: 47.4;renal cancer: 19.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 19.6;prostate cancer: 11.8" "Adipose visceral - Mesothelial cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022493, HPA035628, HPA035629, HPA079220" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 63: Astrocytes - Nervous system maintenance" "CAB022493: , HPA035628: AB_2674708, HPA035629: AB_2674709, HPA079220: " "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "prognostic favorable (7.69e-4)" "unprognostic (5.32e-2)" "unprognostic (1.01e-1)" "unprognostic (5.09e-2)" "unprognostic (4.24e-2)" "unprognostic (7.49e-2)" "unprognostic (1.46e-1)" "unprognostic (9.22e-3)" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.18e-4)" "unprognostic (7.00e-2)" "unprognostic (2.92e-1)" "unprognostic (2.05e-3)" "unprognostic (2.04e-1)" SLC6A19 ENSG00000174358 "Solute carrier family 6 member 19" Q695T7 5 1201595-1225111 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "intestine: 142.4;kidney: 88.7" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 521.3" "Group enriched" "Detected in many" 4 "renal cancer: 7.9;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 5.8;liver cancer: 5.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037415, HPA043207" Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA037415: AB_10672346, HPA043207: AB_2678363" "unprognostic (1.26e-1)" "unprognostic (1.01e-3)" "unprognostic (6.04e-2)" "unprognostic (3.64e-1)" "prognostic favorable (4.14e-6)" "unprognostic (1.37e-1)" "unprognostic (7.36e-2)" SLC6A20 "IMINO, SIT1, XT3, Xtrp3" ENSG00000163817 "Solute carrier family 6 member 20" Q9NP91 3 45755449-45796536 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 59.2;intestine: 24.2" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 70.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 5.2;colorectal cancer: 14.6;Gastric cancer: 11.2;pancreatic cancer: 8.0" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (1.57e-1)" "unprognostic (5.26e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-2)" "unprognostic (1.48e-1)" "unprognostic (9.43e-3)" "unprognostic (3.26e-2)" "unprognostic (4.33e-3)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.55e-5)" "unprognostic (2.87e-1)" "unprognostic (1.23e-1)" "unprognostic (7.55e-2)" "unprognostic (2.09e-2)" SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 570.8;Proximal tubular cells: 381.6;Squamous epithelial cells: 348.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" SOD2 GClnc1 ENSG00000112096 "Superoxide dismutase 2" P04179 6 159669069-159762529 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 1083.7;skeletal muscle: 3230.1" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 2571.2;Ductal cells: 2101.9;Exocrine glandular cells: 1939.0;Glandular and luminal cells: 2209.4;monocytes: 2712.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 4470.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 4470.5" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001814, CAB002013" Supported Enhanced Mitochondria NA NA 55000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 75: Myeloid cells - Innate immune response" Mitochondria "CAB002013: , HPA001814: AB_1080134" "unprognostic (2.47e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-1)" "unprognostic (1.57e-2)" "unprognostic (1.31e-1)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (3.10e-2)" "unprognostic (1.37e-1)" "unprognostic (6.67e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (8.12e-2)" "unprognostic (4.14e-2)" "unprognostic (5.99e-2)" "unprognostic (1.82e-1)" SOX17 ENSG00000164736 "SRY-box transcription factor 17" Q9H6I2 8 54457935-54460892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.1" "Group enriched" "Detected in many" 8 "Adipocytes: 473.4;Endometrial ciliated cells: 370.0;Endothelial cells: 174.1;Glandular and luminal cells: 527.6" "Group enriched" "Detected in many" 4 "endometrial cancer: 122.8;ovarian cancer: 96.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "liver cancer: 10.8;ovarian cancer: 38.8;Rhabdoid: 32.0;Uterine cancer: 34.1" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025594, HPA068399" Enhanced Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm "CAB025594: , HPA068399: AB_2685981" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "prognostic favorable (2.76e-4)" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (3.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.62e-2)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (7.28e-3)" "unprognostic (1.12e-1)" "unprognostic (3.76e-1)" "unprognostic (1.88e-1)" TBC1D8B "FLJ20298, GRAMD8B, RP11-321G1.1" ENSG00000133138 "TBC1 domain family member 8B" Q0IIM8 X 106802673-106876150 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023883, HPA027527" Enhanced Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 52: Spermatids - Smell perception" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol "HPA023883: AB_1857794, HPA027527: AB_2199395" "unprognostic (6.69e-2)" "unprognostic (1.06e-1)" "unprognostic (8.19e-2)" "unprognostic (4.69e-3)" "unprognostic (8.15e-2)" "unprognostic (6.97e-2)" "unprognostic (2.08e-1)" "unprognostic (1.88e-2)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (2.75e-1)" "unprognostic (4.89e-2)" "unprognostic (3.32e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-1)" "unprognostic (9.97e-2)" "unprognostic (5.16e-2)" TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Endothelial cells: 37.1;Fibroblasts: 208.4;Granulosa cells: 59.8;Thymic epithelial cells: 56.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_1, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" TRPC6 "FSGS2, TRP6" ENSG00000137672 "Transient receptor potential cation channel subfamily C member 6" Q9Y210 11 101451564-101872562 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.3;placenta: 20.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 19.0;Inhibitory neurons: 45.9;Microglial cells: 11.9;Smooth muscle cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.6;testis cancer: 2.1" "Adipose subcutaneous - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045098 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "HPA045098: AB_10959600" "unprognostic (1.45e-1)" "unprognostic (4.21e-1)" "unprognostic (2.43e-1)" "unprognostic (8.71e-5)" "unprognostic (1.86e-1)" "unprognostic (1.36e-2)" "unprognostic (4.33e-2)" "unprognostic (1.14e-1)" "unprognostic (4.30e-2)" "unprognostic (3.04e-1)" "unprognostic (1.98e-2)" "unprognostic (1.30e-1)" "unprognostic (5.47e-4)" "unprognostic (1.99e-3)" "unprognostic (4.88e-2)" "unprognostic (7.16e-2)" "unprognostic (1.32e-2)" TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 412.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 55: Non-specific - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favorable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047967-2089491 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 144.6;Horizontal cells: 126.3;Rod photoreceptor cells: 161.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: Non-specific - Transcription" "Cluster 70: Basal prostatic cells - Lipid metabolism" Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favorable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 693 "kidney: 2277.8" "Group enriched" "Detected in some" 164 "Collecting duct cells: 206.8;Distal tubular cells: 410.5" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" NA NA 55000000 66000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 16: Non-specific - RNA binding" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" VEGFA "VEGF, VEGF-A, VPF" ENSG00000112715 "Vascular endothelial growth factor A" P15692 6 43770184-43786487 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 243.8;Langerhans cells: 275.3" "Cancer enhanced" "Detected in all" "renal cancer: 79.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005429, CAB039240, HPA069116, CAB069907" Supported "Secreted to blood" NA NA 562000 57000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 68: Kidney - Mixed function" "Cluster 75: Myeloid cells - Innate immune response" "CAB005429: AB_2212984, CAB039240: , CAB069907: AB_10001947, HPA069116: AB_2686089" "unprognostic (1.12e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (2.42e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.34e-5)" "unprognostic (5.10e-2)" "unprognostic (5.27e-3)" "unprognostic (2.30e-2)" "unprognostic (1.40e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (1.76e-5)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.73e-4)" WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752579-911452 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 293.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Intercalated cells, Lung - Alveolar cells type 1, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol NA NA 92000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 45: Non-specific - Cell proliferation" "Cluster 12: Non-specific - Chromatin organization" Cytosol "HPA046541: AB_2679690, HPA059157: AB_2683935" "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780610-42797066 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0;kidney: 37.6;prostate: 11.6" "Cell type enhanced" "Detected in some" "Distal tubular cells: 174.1;Intestinal goblet cells: 75.0;Prostatic glandular cells: 33.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" WT1 "AWT1, GUD, NPHS4, WAGR, WIT-2" ENSG00000184937 "WT1 transcription factor" P19544 11 32387775-32435564 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 29.5;Endometrial stromal cells: 81.6;Sertoli cells: 135.4;Thymic epithelial cells: 80.7" "Cancer enriched" "Detected in many" 14 "ovarian cancer: 55.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 10.0" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000327, HPA035717, HPA053848" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm Cytosol "CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279" "unprognostic (3.09e-3)" "unprognostic (9.97e-4)" "unprognostic (3.32e-1)" "unprognostic (8.24e-3)" "unprognostic (5.20e-2)" "unprognostic (1.98e-3)" "unprognostic (2.94e-2)" "unprognostic (1.59e-2)" "unprognostic (1.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-10)" "unprognostic (2.65e-3)" "unprognostic (1.87e-1)" "unprognostic (1.96e-3)" "unprognostic (1.30e-2)"