Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 388.0;Cholangiocytes: 196.3;Distal enterocytes: 190.9;Gastric mucus-secreting cells: 499.0;Proximal enterocytes: 373.1;Suprabasal keratinocytes: 540.4" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gallbladder cancer: 2640.5;liver cancer: 687.1" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" AMY1A AMY1 ENSG00000237763 "Amylase alpha 1A" P04745 1 103655290-103664554 "Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 290 "salivary gland: 22089.3" "Cell type enriched" "Detected in some" 30 "Serous glandular cells: 47.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "CAB004310, HPA045394, HPA045399, HPA046980" Enhanced "Secreted to digestive system" NA NA 70000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Enzymes" "Cluster 21: Serous glandular cells - Salivary secretion" "CAB004310: AB_626668, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" AMY1B AMY1 ENSG00000174876 "Amylase alpha 1B" P04745 1 103687415-103696680 "Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "salivary gland: 4607.5" "Cell type enriched" "Detected in some" 22 "Serous glandular cells: 58.7" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 70000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 46: Non-specific - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (7.34e-2)" "unprognostic (2.59e-1)" "unprognostic (6.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.96e-1)" AMY1C AMY1 ENSG00000187733 "Amylase alpha 1C" P04745 1 103750406-103758690 "Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "pancreas: 125.9;salivary gland: 199.3" "Cell type enriched" "Detected in single" 29 "Serous glandular cells: 14.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 70000000 "Cluster 25: Pancreas - Digestion" "Cluster 46: Non-specific - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" AMY2A AMY2 ENSG00000243480 "Amylase alpha 2A" P04746 1 103616811-103625780 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1983 "pancreas: 148689.6" "Group enriched" "Detected in some" 69 "Exocrine glandular cells: 138.1;Respiratory ciliated cells: 125.6" "Cancer enriched" "Detected in single" 2010 "pancreatic cancer: 200.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, CAB045960, HPA046980" Enhanced "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 56: Neurons - Neuronal signaling" "Cluster 20: Airway & Pancreas - Proteolysis" "CAB045960: AB_2226891, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (3.27e-1)" "unprognostic (1.78e-3)" "unprognostic (3.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.13e-2)" AMY2B AMY2 ENSG00000240038 "Amylase alpha 2B" P19961 1 103553815-103579534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 122 "pancreas: 31246.7" "Group enriched" "Detected in many" 7 "Respiratory ciliated cells: 516.7;Serous glandular cells: 393.8" "Cancer enriched" "Detected in many" 15 "pancreatic cancer: 25.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 77000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 52: Spermatids - Smell perception" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (8.69e-4)" "unprognostic (3.71e-3)" "unprognostic (6.41e-2)" "unprognostic (9.75e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-4)" "unprognostic (1.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (7.41e-3)" "unprognostic (1.55e-2)" "unprognostic (5.74e-2)" "unprognostic (4.22e-1)" "unprognostic (3.12e-4)" BPIFA2 "bA49G10.1, C20orf70, PSP, SPLUNC2" ENSG00000131050 "BPI fold containing family A member 2" Q96DR5 20 33161768-33181412 "Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1619 "salivary gland: 6860.0" "Cell type enriched" "Detected in some" 17 "Serous glandular cells: 4679.0" "Group enriched" "Detected in some" 4 "lung cancer: 2.6;pancreatic cancer: 2.9;stomach cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.5;lung cancer: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA044006 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Enzymes" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA044006: AB_10963580" "unprognostic (9.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (3.56e-2)" "unprognostic (3.03e-2)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.04e-1)" "unprognostic (6.14e-4)" C6orf58 LEG1 ENSG00000184530 "Chromosome 6 open reading frame 58" Q6P5S2 6 127519455-127591820 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 612.7;salivary gland: 2257.3" "Cell type enhanced" "Detected in some" "Club cells: 7.6;Early spermatids: 20.3;Gastric mucus-secreting cells: 47.1;Mucus glandular cells: 8.8" "Group enriched" "Detected in some" 6 "pancreatic cancer: 17.1;stomach cancer: 14.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.9" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036263, HPA041449" Enhanced "Secreted to digestive system" NA NA 30000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 58: Gastric mucus-secreting cells - Digestion" "HPA036263: AB_10673349, HPA041449: AB_2677486" "unprognostic (1.49e-1)" "unprognostic (8.55e-2)" "unprognostic (2.71e-1)" "unprognostic (5.69e-2)" "unprognostic (3.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (3.26e-2)" "unprognostic (7.72e-3)" "unprognostic (1.69e-1)" "unprognostic (6.62e-4)" "unprognostic (2.10e-2)" "unprognostic (2.31e-1)" "unprognostic (1.53e-2)" "unprognostic (8.99e-3)" CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 295 "salivary gland: 9393.1" "Cell type enriched" "Detected in some" 47 "Serous glandular cells: 7232.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.6;naive CD8 T-cell: 16.4" "Lineage enriched" "Detected in many" 11 "T-cells: 16.4" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.6" "Breast - Breast glandular cells (progenitors)" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" NA NA 24000000 "Cluster 32: T-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 2: DU4475 - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA028550: AB_10600105, HPA028692: AB_10601883" "unprognostic (2.54e-5)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (9.28e-2)" "unprognostic (2.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (5.93e-2)" "unprognostic (4.41e-2)" "unprognostic (4.29e-5)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" CBLIF "GIF, IF, IFMH, INF, TCN3" ENSG00000134812 "Cobalamin binding intrinsic factor" P27352 11 59829273-59845499 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1859 "stomach 1: 1575.7" "Cell type enriched" "Detected in some" 112 "Gastric mucus-secreting cells: 343.4" "Cancer enriched" "Detected in some" 11 "stomach cancer: 10.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "ovarian cancer: 2.0" "Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039908, HPA040774" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "Cluster 39: Non-specific - Unknown function" "Cluster 58: Gastric mucus-secreting cells - Digestion" "HPA039908: AB_10796335, HPA040774: AB_10795626" "unprognostic (2.78e-4)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (3.59e-1)" "unprognostic (1.66e-1)" CEL "BSSL, MODY8" ENSG00000170835 "Carboxyl ester lipase" P19835 9 133061981-133071861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 548 "pancreas: 110578.0" "Cell type enriched" "Detected in some" 9 "Respiratory ciliated cells: 3485.0" "Cancer enriched" "Detected in many" 29 "pancreatic cancer: 469.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 14.6" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008023, HPA052701" Enhanced "Secreted to digestive system" NA NA 110000 "Cluster 25: Pancreas - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA008023: AB_1846509, HPA052701: AB_2681921" "prognostic unfavorable (4.14e-4)" "unprognostic (2.30e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-2)" "unprognostic (2.22e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (6.27e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (5.55e-2)" "unprognostic (2.26e-3)" "unprognostic (2.98e-1)" "unprognostic (4.41e-1)" "unprognostic (4.37e-2)" "unprognostic (1.02e-1)" CELA2A ELA2A ENSG00000142615 "Chymotrypsin like elastase 2A" P08217 1 15456728-15472091 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2325 "pancreas: 162732.5" "Group enriched" "Detected in some" 28 "Exocrine glandular cells: 2032.3;Respiratory ciliated cells: 2088.5" "Cancer enriched" "Detected in single" 3818 "pancreatic cancer: 463.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Secreted to digestive system" NA NA 2700000 "Cluster 25: Pancreas - Digestion" "Cluster 39: Non-specific - Unknown function" "Cluster 20: Airway & Pancreas - Proteolysis" "unprognostic (9.78e-2)" "unprognostic (3.33e-2)" "unprognostic (5.60e-2)" "unprognostic (5.27e-2)" "unprognostic (3.63e-3)" "unprognostic (2.35e-1)" "unprognostic (4.14e-1)" "unprognostic (1.96e-2)" "unprognostic (1.38e-1)" "unprognostic (2.48e-1)" "unprognostic (3.94e-9)" "unprognostic (4.10e-2)" "unprognostic (3.42e-1)" "unprognostic (3.55e-2)" CELA2B "ELA2B, RP11-265F14.2" ENSG00000215704 "Chymotrypsin like elastase 2B" P08218 1 15465909-15491395 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1672 "pancreas: 20446.9" "Cell type enriched" "Detected in some" 6 "Respiratory ciliated cells: 1892.2" "Cancer enriched" "Detected in single" 574 "pancreatic cancer: 69.9" "Group enriched" "Detected in some" 4 "cerebellum: 2.0;cerebral cortex: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Secreted to digestive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 25: Pancreas - Digestion" "Cluster 40: Non-specific - Enzymes" "Cluster 20: Airway & Pancreas - Proteolysis" "unprognostic (4.36e-3)" "unprognostic (5.45e-2)" "unprognostic (6.66e-2)" "unprognostic (5.31e-3)" "unprognostic (4.47e-3)" "unprognostic (1.37e-3)" "unprognostic (4.66e-2)" "unprognostic (6.32e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-1)" "unprognostic (2.94e-1)" "unprognostic (3.85e-2)" "unprognostic (1.22e-6)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-1)" "unprognostic (7.80e-2)" CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase 3A" P09093 1 22001657-22012542 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2216 "pancreas: 262614.2" "Group enriched" "Detected in some" 32 "Exocrine glandular cells: 7786.9;Respiratory ciliated cells: 2994.3" "Cancer enriched" "Detected in some" 2497 "pancreatic cancer: 1481.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "ovarian cancer: 1.3" "Pancreas - Exocrine glandular cells" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 20: Airway & Pancreas - Proteolysis" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.79e-1)" "unprognostic (6.32e-2)" "unprognostic (2.67e-1)" CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase 3B" P08861 1 21977022-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2088 "pancreas: 49621.1" "Group enriched" "Detected in some" 21 "Exocrine glandular cells: 3015.7;Respiratory ciliated cells: 1415.5" "Cancer enriched" "Detected in single" 1218 "pancreatic cancer: 408.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells, Stomach - Chief cells, Testis - Late spermatids" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 20: Airway & Pancreas - Proteolysis" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (2.89e-1)" "unprognostic (4.01e-3)" "unprognostic (6.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (6.40e-2)" CLCA1 "CaCC, CLCRG1" ENSG00000016490 "Chloride channel accessory 1" A8K7I4 1 86468368-86500259 "Predicted secreted proteins, Transporters" "Calcium transport, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 1399.9" "Cell type enriched" "Detected in some" 39 "Intestinal goblet cells: 5583.7" "Group enriched" "Detected in some" 9 "colorectal cancer: 86.8;pancreatic cancer: 27.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "ovarian cancer: 30.8" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052787, HPA059301" Enhanced "Secreted to digestive system" NA NA 77000 "Cluster 9: Intestine - Unknown function" "Cluster 39: Non-specific - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA052787: AB_2681947, HPA059301: AB_2683971" "prognostic favorable (2.98e-4)" "unprognostic (3.42e-1)" "unprognostic (8.61e-2)" "unprognostic (1.06e-1)" CLPS ENSG00000137392 Colipase P04118 6 35794982-35797344 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Digestion, Lipid degradation, Lipid metabolism" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1696 "pancreas: 262086.0" "Group enriched" "Detected in some" 76 "Exocrine glandular cells: 5915.0;Respiratory ciliated cells: 21411.6" "Cancer enriched" "Detected in many" 188 "pancreatic cancer: 1726.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "breast cancer: 2.3" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA010512 Enhanced "Secreted to digestive system" NA NA 1600000 "Cluster 15: NK-cells - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 65: Breast cancer - Unknown function" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA010512: AB_1846979" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.12e-3)" "unprognostic (2.47e-1)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2326 "pancreas: 237498.3" "Group enriched" "Detected in some" 25 "Exocrine glandular cells: 3215.3;Respiratory ciliated cells: 12223.7" "Cancer enriched" "Detected in some" 639 "pancreatic cancer: 1377.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.2;Sarcoma: 1.2;Uterine cancer: 1.1" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" NA NA 110000000 "Cluster 25: Pancreas - Digestion" "Cluster 41: Non-specific - Cilium assembly" "Cluster 20: Airway & Pancreas - Proteolysis" "CAB025197: , HPA021836: AB_1846005, HPA052215: AB_2681764" "unprognostic (8.41e-2)" "unprognostic (9.24e-4)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-6)" "unprognostic (4.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (4.37e-2)" CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266863-130289798 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 416 "pancreas: 45360.2" "Group enriched" "Detected in some" 8 "Exocrine glandular cells: 1636.4;Respiratory ciliated cells: 2006.8" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 2.6" "Pancreas - Exocrine glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" NA NA 1500000 "Cluster 25: Pancreas - Digestion" "Cluster 39: Non-specific - Unknown function" "Cluster 20: Airway & Pancreas - Proteolysis" "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" CPB1 ENSG00000153002 "Carboxypeptidase B1" P15086 3 148791102-148860187 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1970 "pancreas: 226925.8" "Cell type enriched" "Detected in some" 4 "Respiratory ciliated cells: 10752.1" "Group enriched" "Detected in some" 312 "breast cancer: 293.8;pancreatic cancer: 641.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 13 "Rhabdoid: 13.8" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026158, HPA038069, HPA046340" Enhanced "Secreted to digestive system" NA NA 88000000 "Cluster 17: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 20: Airway & Pancreas - Proteolysis" "CAB026158: , HPA038069: AB_2675816, HPA046340: AB_2679628" "unprognostic (6.90e-2)" "unprognostic (3.79e-2)" "unprognostic (3.34e-2)" "unprognostic (2.64e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (6.26e-4)" "unprognostic (1.90e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (7.59e-2)" "unprognostic (4.51e-2)" "unprognostic (5.50e-8)" "unprognostic (3.08e-1)" "unprognostic (1.60e-1)" "unprognostic (4.93e-2)" CST1 ENSG00000170373 "Cystatin SN" P01037 20 23747562-23751268 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 119 "salivary gland: 28401.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 19.2;Collecting duct cells: 82.7;Glandular and luminal cells: 34.9;Prostatic glandular cells: 62.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 116.1" "CAB026769, HPA043706, HPA044763" Enhanced "Secreted to digestive system" NA NA 6300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 2: DU4475 - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "CAB026769: , HPA043706: AB_2678627, HPA044763: AB_2679080" "prognostic favorable (4.00e-4)" "unprognostic (2.47e-1)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (1.99e-1)" "unprognostic (5.27e-2)" "unprognostic (1.99e-1)" "unprognostic (1.56e-1)" "unprognostic (1.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (8.26e-2)" "unprognostic (9.58e-2)" "unprognostic (2.58e-1)" "unprognostic (9.00e-2)" "unprognostic (9.91e-3)" CST2 ENSG00000170369 "Cystatin SA" P09228 20 23823769-23826729 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 637 "salivary gland: 5987.1" "Cell type enriched" "Detected in some" 12 "Serous glandular cells: 243.8" "Cancer enhanced" "Detected in many" "prostate cancer: 24.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 12.2" "CAB024963, HPA043706, HPA044763" Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" "CAB024963: , HPA043706: AB_2678627, HPA044763: AB_2679080" "unprognostic (1.57e-2)" "unprognostic (3.23e-2)" "unprognostic (1.04e-1)" "unprognostic (3.10e-1)" "unprognostic (1.64e-2)" "unprognostic (5.17e-3)" "unprognostic (1.28e-2)" "unprognostic (2.75e-3)" "unprognostic (2.73e-1)" "unprognostic (4.82e-3)" "unprognostic (6.43e-3)" "unprognostic (2.51e-1)" "unprognostic (4.58e-11)" "unprognostic (1.29e-3)" "unprognostic (3.22e-1)" "unprognostic (4.30e-1)" "unprognostic (1.71e-1)" CST4 ENSG00000101441 "Cystatin S" P01036 20 23685640-23689038 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 514 "salivary gland: 29036.2" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 61.4;Prostatic glandular cells: 36.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 21.8;liver cancer: 43.4" "HPA043706, HPA044763" Supported "Secreted to digestive system" NA NA 2800000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: BEWO - Unknown function" "Cluster 70: Basal prostatic cells - Lipid metabolism" "HPA043706: AB_2678627, HPA044763: AB_2679080" "unprognostic (2.80e-1)" "unprognostic (7.88e-2)" "unprognostic (2.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (4.98e-5)" "unprognostic (1.00e-2)" "unprognostic (9.52e-2)" "unprognostic (2.11e-2)" "unprognostic (2.31e-1)" "unprognostic (7.95e-2)" "prognostic favorable (2.88e-4)" CST5 ENSG00000170367 "Cystatin D" P28325 20 23875934-23879748 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 959 "salivary gland: 2156.1" "Cell type enriched" "Detected in some" 33 "Serous glandular cells: 274.2" "Cancer enriched" "Detected in many" 5 "breast cancer: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.9;colorectal cancer: 2.3;Esophageal cancer: 2.1" "CAB024944, HPA061449" Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 21: Serous glandular cells - Salivary secretion" "CAB024944: , HPA061449: AB_2684523" "unprognostic (2.43e-1)" "unprognostic (8.83e-2)" "unprognostic (3.20e-1)" "unprognostic (3.19e-1)" "unprognostic (1.51e-2)" "unprognostic (4.73e-1)" "unprognostic (4.31e-2)" "unprognostic (1.76e-2)" "unprognostic (2.32e-1)" "unprognostic (1.35e-1)" "unprognostic (4.83e-3)" "unprognostic (5.14e-2)" "unprognostic (2.31e-1)" CTRB1 CTRB ENSG00000168925 "Chymotrypsinogen B1" P17538 16 75218988-75226338 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2384 "pancreas: 133851.7" "Group enriched" "Detected in some" 17 "Exocrine glandular cells: 9291.9;Respiratory ciliated cells: 13818.4" "Cancer enriched" "Detected in some" 1905 "pancreatic cancer: 962.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 20: Airway & Pancreas - Proteolysis" "unprognostic (1.76e-1)" "unprognostic (2.62e-1)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (5.22e-2)" "unprognostic (4.43e-3)" "unprognostic (2.96e-1)" "unprognostic (1.17e-2)" CTRB2 ENSG00000168928 "Chymotrypsinogen B2" Q6GPI1 16 75204103-75207161 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2443 "pancreas: 98661.0" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 21332.4" "Cancer enriched" "Detected in single" 1696 "pancreatic cancer: 540.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 51: Myeloma - Humoral immune response" "Cluster 74: Pancreatic cells - Mixed function" "unprognostic (9.41e-4)" "unprognostic (2.20e-1)" "unprognostic (1.28e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-2)" "unprognostic (2.77e-1)" "unprognostic (5.95e-2)" "unprognostic (9.56e-2)" "unprognostic (3.54e-3)" "unprognostic (7.06e-2)" "unprognostic (2.17e-1)" "unprognostic (7.57e-2)" CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438442-15449242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3927 "pancreas: 25708.5" "Group enriched" "Detected in some" 15 "Exocrine glandular cells: 2235.1;Respiratory ciliated cells: 5818.0" "Cancer enriched" "Detected in some" 168 "pancreatic cancer: 236.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046920 Enhanced "Secreted to digestive system" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 52: Spermatids - Smell perception" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA046920: AB_2679865" "unprognostic (2.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (8.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-2)" "unprognostic (7.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-11)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (5.99e-3)" CTRL ENSG00000141086 "Chymotrypsin like" P40313 16 67927640-67932365 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1154 "pancreas: 7481.6" "Group enriched" "Detected in some" 22 "Exocrine glandular cells: 101.5;Respiratory ciliated cells: 291.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034504, HPA034505" Enhanced "Secreted to digestive system" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 17: RS4;11 - Unknown function" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA034504: AB_2674196, HPA034505: AB_10602212" "unprognostic (3.03e-5)" "unprognostic (3.53e-3)" "unprognostic (3.46e-2)" "unprognostic (1.37e-1)" "unprognostic (9.66e-2)" "unprognostic (2.00e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (6.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.88e-1)" "unprognostic (3.20e-4)" "unprognostic (6.69e-2)" "unprognostic (2.79e-1)" "unprognostic (2.63e-1)" "unprognostic (1.29e-3)" DEFA5 "DEF5, HD-5" ENSG00000164816 "Defensin alpha 5" Q01523 8 7055304-7056739 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 768 "intestine: 9759.8" "Cell type enriched" "Detected in some" 19 "Undifferentiated cells: 24300.7" "Cancer enhanced" "Detected in many" "cervical cancer: 181.1;colorectal cancer: 147.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "Gastric cancer: 129.7" "HPA015309, HPA015775, CAB069919" Enhanced Approved Vesicles,Midbody "Secreted to digestive system" Yes NA 110000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" Vesicles Midbody "CAB069919: AB_905358, HPA015309: , HPA015775: AB_1847594" "prognostic favorable (9.44e-5)" "unprognostic (3.91e-2)" DEFA6 "DEF6, HD-6" ENSG00000164822 "Defensin alpha 6" Q01524 8 6924697-6926076 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 863 "intestine: 4819.9" "Cell type enriched" "Detected in some" 35 "Undifferentiated cells: 10201.9" "Group enriched" "Detected in many" 5 "cervical cancer: 21.2;colorectal cancer: 75.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.9;Gastric cancer: 13.8" HPA019462 Enhanced "Secreted to digestive system" NA NA 260000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA019462: AB_1847595" "unprognostic (7.48e-3)" "unprognostic (1.63e-1)" "unprognostic (1.34e-1)" DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591879-36600804 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "intestine: 216.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 217.1;Distal enterocytes: 277.8;Paneth cells: 117.9;Proximal enterocytes: 541.9;Undifferentiated cells: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" NA NA 42000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 56: Intestine - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 50: Enterocytes - Absorption" Cytosol "Golgi apparatus" "HPA041226: AB_2677372, HPA048236: AB_2680322, HPA053623: AB_2682209" "unprognostic (2.00e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.80e-2)" "unprognostic (3.67e-1)" "unprognostic (5.94e-2)" "unprognostic (1.33e-2)" "unprognostic (4.11e-2)" "prognostic favorable (3.24e-4)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" FAM3D "EF7, OIT1" ENSG00000198643 "FAM3 metabolism regulating signaling molecule D" Q96BQ1 3 58633946-58666834 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 264.8;intestine: 488.7;salivary gland: 468.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 362.6;Distal enterocytes: 895.2;Enteroendocrine cells: 314.4;Intestinal goblet cells: 1080.9;Ionocytes: 345.5;Paneth cells: 577.0;Proximal enterocytes: 354.1;Serous glandular cells: 524.0;Undifferentiated cells: 471.2" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 151.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Lineage enhanced" "Detected in single" "granulocytes: 3.7" "Group enriched" "Detected in some" 5 "colorectal cancer: 27.4;Gastric cancer: 12.9" "Colon - Colon enterocytes, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013844 Approved "Secreted to digestive system" NA NA 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA013844: AB_2668897" "prognostic favorable (7.51e-4)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.67e-2)" "unprognostic (5.51e-2)" "prognostic favorable (1.89e-4)" "unprognostic (7.97e-2)" "unprognostic (6.54e-2)" "unprognostic (7.43e-2)" "unprognostic (5.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-4)" "unprognostic (2.34e-2)" GAST GAS ENSG00000184502 Gastrin P01350 17 41712331-41715969 "Cancer-related genes, FDA approved drug targets, Predicted secreted proteins" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "stomach 1: 9556.1" "Group enriched" "Detected in some" 5 "Glandular and luminal cells: 106.9;Plasma cells: 65.4" "Group enriched" "Detected in many" 6 "pancreatic cancer: 38.8;stomach cancer: 23.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 10.8;head and neck cancer: 5.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" CAB000038 Enhanced "Secreted to digestive system" NA NA 87000 "Cluster 4: Stomach - Digestion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 34: Plasma cells - Humoral immune response" "CAB000038: " "unprognostic (1.27e-1)" "unprognostic (4.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.75e-2)" "unprognostic (5.68e-2)" "unprognostic (2.11e-1)" "unprognostic (2.85e-1)" "unprognostic (3.17e-1)" "unprognostic (9.07e-2)" GKN1 "AMP18, BRICD1, CA11" ENSG00000169605 "Gastrokine 1" Q9NS71 2 68974573-68980980 "Plasma proteins, Predicted secreted proteins" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1840 "stomach 1: 37425.0" "Cell type enriched" "Detected in some" 451 "Gastric mucus-secreting cells: 8516.1" "Cancer enriched" "Detected in some" 116 "stomach cancer: 255.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "Bladder cancer: 18.1" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA047684 Enhanced "Secreted to digestive system" NA NA 18000000 "Cluster 4: Stomach - Digestion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 58: Gastric mucus-secreting cells - Digestion" "HPA047684: AB_2680120" "unprognostic (5.40e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.54e-1)" "prognostic favorable (4.53e-4)" GKN2 "blottin, BRICD1B, GDDR, PRO813, TFIZ1, VLTI465" ENSG00000183607 "Gastrokine 2" Q86XP6 2 68945232-68952893 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "stomach 1: 4612.5" "Cell type enriched" "Detected in some" 5 "Gastric mucus-secreting cells: 2395.5" "Cancer enriched" "Detected in some" 8 "stomach cancer: 43.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "ovarian cancer: 3.4;pancreatic cancer: 6.6;prostate cancer: 2.6;thyroid cancer: 4.2" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA057765 Enhanced "Secreted to digestive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 58: Gastric mucus-secreting cells - Digestion" "HPA057765: AB_2683520" "unprognostic (1.81e-1)" "unprognostic (1.44e-4)" "unprognostic (2.22e-1)" GP2 ZAP75 ENSG00000169347 "Glycoprotein 2" P55259 16 20309574-20327808 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 966 "pancreas: 35381.6" "Cell type enriched" "Detected in some" 24 "Respiratory ciliated cells: 4453.7" "Cancer enriched" "Detected in many" 14 "pancreatic cancer: 320.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "breast cancer: 6.5" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015739, HPA016668" Enhanced "Secreted to digestive system" NA NA 41000 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 65: Breast cancer - Unknown function" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA015739: AB_1849905, HPA016668: AB_1849907" "unprognostic (2.14e-2)" "unprognostic (1.97e-2)" "unprognostic (5.68e-2)" "unprognostic (4.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.84e-1)" "unprognostic (6.35e-2)" "unprognostic (8.17e-3)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" HTN1 HIS1 ENSG00000126550 "Histatin 1" P15515 4 70050438-70058848 "Predicted secreted proteins, Transporters" Biomineralization "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2602 "salivary gland: 48372.4" "Cell type enriched" "Detected in some" 33 "Serous glandular cells: 71521.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077315 Approved "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA077315: " "unprognostic (2.22e-1)" HTN3 HIS2 ENSG00000205649 "Histatin 3" P15516 4 70028455-70036538 "Predicted secreted proteins, Transporters" Biomineralization "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1102 "salivary gland: 136053.4" "Cell type enriched" "Detected in some" 32 "Serous glandular cells: 208255.3" "Cancer enhanced" "Detected in single" "melanoma: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 3.8" CAB073541 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 21: Serous glandular cells - Salivary secretion" "CAB073541: " INS-IGF2 ENSG00000129965 "INS-IGF2 readthrough" F8WCM5 11 2132538-2161209 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 48 "pancreas: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Pancreas - Beta cells" "CAB019430, HPA071234" Enhanced Uncertain Nucleoplasm "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" Nucleoplasm "CAB019430: AB_10691857, HPA071234: " "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" ITLN2 HL-2 ENSG00000158764 "Intelectin 2" Q8WWU7 1 160945025-160954809 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "intestine: 408.3" "Cell type enriched" "Detected in some" 4 "Undifferentiated cells: 264.0" "Group enriched" "Detected in many" 4 "colorectal cancer: 2.8;testis cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 5.2;pancreatic cancer: 2.8;testis cancer: 3.8" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "HPA006683, HPA067326" Enhanced "Secreted to digestive system" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 6: BEWO - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA006683: AB_2129681, HPA067326: AB_2732764" "unprognostic (1.42e-1)" "unprognostic (9.62e-3)" "unprognostic (4.61e-2)" "unprognostic (7.45e-2)" "unprognostic (2.25e-1)" "unprognostic (6.84e-4)" "unprognostic (2.47e-2)" "unprognostic (5.74e-2)" "unprognostic (1.31e-2)" "unprognostic (1.36e-1)" "unprognostic (5.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.49e-1)" "unprognostic (2.31e-1)" "unprognostic (4.91e-2)" KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819146-50823787 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 84 "pancreas: 9557.9;salivary gland: 5487.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 373.8;Intestinal goblet cells: 1109.3;Respiratory ciliated cells: 853.8;Salivary duct cells: 217.9;Undifferentiated cells: 207.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "memory B-cell: 9.5;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 13 "B-cells: 9.5" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 12.1" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells" HPA059690 Approved "Secreted to digestive system" NA NA 10000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA059690: " "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" LACRT LACRITIN ENSG00000135413 Lacritin Q9GZZ8 12 54630811-54634895 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "salivary gland: 13.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 304 "breast cancer: 15.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells" "Secreted to digestive system" NA NA 230000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 65: Breast cancer - Unknown function" LIPF "HGL, HLAL" ENSG00000182333 "Lipase F, gastric type" P07098 10 88664441-88678814 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 142 "stomach 1: 37213.5" "Cell type enriched" "Detected in some" 351 "Gastric mucus-secreting cells: 1646.7" "Cancer enriched" "Detected in some" 75 "stomach cancer: 278.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Chief cells" "Region enriched" "Detected in single" 77 "olfactory bulb: 7.6" HPA045930 Enhanced "Secreted to digestive system" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 65: Breast cancer - Unknown function" "Cluster 58: Gastric mucus-secreting cells - Digestion" "HPA045930: AB_10959518" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 404 "salivary gland: 1026.8" "Cell type enriched" "Detected in some" 33 "Serous glandular cells: 941.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.3" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028688 Enhanced Supported "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA028688: AB_10601909" "unprognostic (2.74e-1)" "unprognostic (5.12e-2)" "unprognostic (4.14e-3)" "unprognostic (1.56e-3)" "unprognostic (2.41e-2)" "unprognostic (9.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (6.27e-3)" "unprognostic (6.32e-2)" "unprognostic (2.56e-1)" "unprognostic (0.00e+0)" "unprognostic (3.41e-2)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (1.22e-1)" LYPD8 ENSG00000259823 "LY6/PLAUR domain containing 8" Q6UX82 1 248739415-248755759 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 215.9" "Group enriched" "Detected in some" 4 "Distal enterocytes: 278.9;Paneth cells: 1060.5" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 15.2" "Group enriched" "Detected in many" 10 "amygdala: 1.1;basal ganglia: 1.6;cerebral cortex: 1.9;hippocampal formation: 1.1;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.3;lung cancer: 2.0" "Colon - Colon enterocytes" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "unprognostic (6.69e-3)" "unprognostic (3.53e-2)" "unprognostic (1.08e-5)" "unprognostic (1.42e-2)" "unprognostic (1.35e-1)" "unprognostic (2.16e-4)" "unprognostic (8.62e-2)" "unprognostic (7.28e-2)" "unprognostic (3.22e-1)" "unprognostic (9.73e-2)" "unprognostic (1.87e-1)" "unprognostic (1.19e-4)" "unprognostic (2.57e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" MEP1B ENSG00000141434 "Meprin A subunit beta" Q16820 18 32185069-32220404 "Enzymes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "intestine: 363.9" "Cell type enriched" "Detected in some" 50 "Proximal enterocytes: 202.6" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.7;Myeloma: 2.7" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA029119 Enhanced "Secreted to digestive system" NA NA 310000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA029119: AB_2672913" "unprognostic (1.33e-1)" "unprognostic (6.72e-2)" "unprognostic (2.79e-2)" "unprognostic (1.00e-1)" "unprognostic (3.50e-4)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (4.30e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-4)" "unprognostic (4.74e-2)" "unprognostic (3.39e-1)" "unprognostic (2.71e-1)" "unprognostic (3.39e-2)" "unprognostic (3.75e-2)" MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 614.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 437.7;Endometrial ciliated cells: 117.6;Enteroendocrine cells: 163.6;Intestinal goblet cells: 440.6;Paneth cells: 328.1;Proximal enterocytes: 406.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 198.4;stomach cancer: 152.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 166.1;Gastric cancer: 61.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA045163: AB_10960396, HPA079663: " "unprognostic (8.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (2.93e-1)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.94e-1)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (9.64e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (2.05e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" MUC5AC MUC5 ENSG00000215182 "Mucin 5AC, oligomeric mucus/gel-forming" P98088 11 1157953-1201138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 101 "stomach 1: 185.1" "Cell type enriched" "Detected in some" 34 "Gastric mucus-secreting cells: 8981.8" "Group enriched" "Detected in many" 4 "pancreatic cancer: 25.3;stomach cancer: 61.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 26.9;pancreatic cancer: 15.8" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002774, CAB009395, HPA040615, HPA070378, HPA077637" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "Cluster 65: Breast cancer - Unknown function" "Cluster 58: Gastric mucus-secreting cells - Digestion" "CAB002774: , CAB009395: AB_2146854, HPA040615: AB_2677042, HPA070378: , HPA077637: " "unprognostic (2.10e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (3.14e-2)" "unprognostic (1.72e-2)" "unprognostic (2.51e-2)" "unprognostic (4.56e-2)" "unprognostic (6.49e-2)" "unprognostic (2.44e-2)" "unprognostic (1.30e-3)" "unprognostic (8.46e-2)" "unprognostic (5.83e-4)" "unprognostic (1.84e-1)" "unprognostic (9.21e-3)" "unprognostic (4.07e-1)" "unprognostic (1.37e-1)" MUC6 ENSG00000184956 "Mucin 6, oligomeric mucus/gel-forming" Q6W4X9 11 1012823-1036718 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "pancreas: 171.2;stomach 1: 409.9" "Group enriched" "Detected in some" 6 "Basal prostatic cells: 293.0;Gastric mucus-secreting cells: 282.6" "Group enriched" "Detected in many" 4 "pancreatic cancer: 42.9;stomach cancer: 58.0" "Region enhanced" "Detected in single" "amygdala: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB002165 Enhanced "Secreted to digestive system" NA NA 75000 "Cluster 25: Pancreas - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 70: Basal prostatic cells - Lipid metabolism" "CAB002165: AB_442114" "unprognostic (1.90e-2)" "unprognostic (1.00e-1)" "unprognostic (5.21e-3)" "unprognostic (1.56e-3)" "unprognostic (1.04e-1)" "unprognostic (5.17e-3)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (1.65e-2)" "unprognostic (2.63e-1)" "unprognostic (9.46e-2)" "unprognostic (8.62e-2)" "unprognostic (3.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (4.72e-2)" "unprognostic (5.23e-2)" MUC7 "FLJ27047, MG2" ENSG00000171195 "Mucin 7, secreted" Q8TAX7 4 70430492-70482997 "Disease related genes, Predicted secreted proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 875 "salivary gland: 26019.1" "Cell type enriched" "Detected in some" 16 "Mucus glandular cells: 4673.1" "Group enriched" "Detected in some" 12 "head and neck cancer: 8.1;melanoma: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "skin cancer: 1.5" "Skin - Eccrine sweat gland cells" HPA006411 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 33: Skin cancer - Membrane components" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA006411: AB_1854204" "unprognostic (5.49e-2)" "unprognostic (3.20e-1)" "unprognostic (1.06e-1)" NRG4 HRG4 ENSG00000169752 "Neuregulin 4" Q8WWG1 15 75935969-76059795 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;retina: 4.3" "Cell type enhanced" "Detected in many" "Early spermatids: 17.9;Exocrine glandular cells: 18.1;Gastric mucus-secreting cells: 31.6;Prostatic glandular cells: 15.9;Rod photoreceptor cells: 29.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "cerebellum: 3.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.2" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010957 Uncertain "Secreted to digestive system" NA NA "Cluster 77: Retina - Visual perception" "Cluster 61: Liver - Metabolism" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA010957: AB_1079504" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (3.94e-2)" "unprognostic (1.67e-2)" "unprognostic (5.66e-2)" "unprognostic (4.10e-2)" "unprognostic (1.12e-2)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (2.82e-5)" "unprognostic (1.91e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-5)" "unprognostic (8.28e-2)" "unprognostic (7.45e-2)" "unprognostic (1.08e-2)" "unprognostic (2.06e-1)" NTS ENSG00000133636 Neurotensin P30990 12 85874295-85882992 "Predicted secreted proteins" Vasoactive "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 165.8" "Cell type enriched" "Detected in some" 132 "Enteroendocrine cells: 17684.4" "Cancer enhanced" "Detected in many" "lung cancer: 155.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 389.6;ovarian cancer: 547.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 154.3" "HPA026664, HPA071012" Enhanced Supported Vesicles "Secreted to digestive system" NA NA 1600000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 55: Endocrine cells - Hormone signaling" Vesicles "HPA026664: AB_2671936, HPA071012: " "unprognostic (3.63e-1)" "prognostic favorable (9.94e-5)" "unprognostic (8.18e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (7.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-3)" "unprognostic (8.83e-2)" "unprognostic (1.74e-2)" "unprognostic (3.76e-2)" "unprognostic (1.30e-6)" "unprognostic (2.94e-2)" "unprognostic (2.25e-1)" "unprognostic (2.17e-1)" "unprognostic (7.48e-2)" NXPE4 "C11orf33, FAM55D, FLJ20127" ENSG00000137634 "Neurexophilin and PC-esterase domain family member 4" Q6UWF7 11 114570591-114595786 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 119.6;salivary gland: 77.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 137.7;Enteroendocrine cells: 75.6;Intestinal goblet cells: 93.7;Paneth cells: 35.1;Serous glandular cells: 29.4;Undifferentiated cells: 56.6" "Cancer enriched" "Detected in some" 15 "colorectal cancer: 13.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Colon - Colon enterocytes" "Low region specificity" "Detected in all" HPA042801 Enhanced "Secreted to digestive system" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA042801: AB_10793986" "unprognostic (1.35e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-3)" "unprognostic (1.27e-1)" "unprognostic (3.51e-3)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (7.47e-3)" "unprognostic (4.36e-2)" "unprognostic (2.05e-1)" OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Club cells: 912.1;Ductal cells: 550.8;Enteroendocrine cells: 425.1;Exocrine glandular cells: 1845.5;Undifferentiated cells: 2310.8" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "colorectal cancer: 127.6;Gastric cancer: 51.3" "Colon - Colon enterocytes, Lung - Neutrophil_1, Prostate - Urothelial cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" PGA3 ENSG00000229859 "Pepsinogen A3" P0DJD8 11 61203307-61213098 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 613 "stomach 1: 89073.4" "Cell type enriched" "Detected in some" 53 "Gastric mucus-secreting cells: 3636.2" "Cancer enriched" "Detected in single" 498 "stomach cancer: 24.8" "Region enhanced" "Detected in single" "hippocampal formation: 2.9" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "CAB026358, HPA046875" Enhanced "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 62: Granulocytes - Innate immune response" "Cluster 58: Gastric mucus-secreting cells - Digestion" "CAB026358: , HPA046875: AB_2679851" "unprognostic (6.39e-2)" "unprognostic (1.11e-1)" PGA4 ENSG00000229183 "Pepsinogen A4" P0DJD7 11 61222349-61231694 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1281 "stomach 1: 66596.4" "Group enriched" "Detected in some" 8 "Exocrine glandular cells: 21.5;Gastric mucus-secreting cells: 17.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "classical monocyte: 9.9;intermediate monocyte: 10.9;non-classical monocyte: 3.4" "Lineage enriched" "Detected in single" 26 "monocytes: 10.9" "Not detected" "Not detected" "Stomach - Chief cells" HPA046875 Supported "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 62: Granulocytes - Innate immune response" "Cluster 74: Pancreatic cells - Mixed function" "HPA046875: AB_2679851" "unprognostic (2.22e-1)" PGA5 ENSG00000256713 "Pepsinogen A5" P0DJD9 11 61241175-61251444 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2014 "stomach 1: 39870.8" "Cell type enriched" "Detected in some" 14 "Exocrine glandular cells: 936.5" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 29 "classical monocyte: 1.8;intermediate monocyte: 4.3;non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 44 "monocytes: 4.3" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Stomach - Chief cells" HPA046875 Supported "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 74: Pancreatic cells - Mixed function" "HPA046875: AB_2679851" "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "stomach 1: 59821.1" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 2440.7;Gastric mucus-secreting cells: 6245.8" "Cancer enhanced" "Detected in many" "stomach cancer: 1050.3" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 19 "Gastric cancer: 459.0" "Lung - Alveolar cells type 2, Stomach - Chief cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm "HPA031717: AB_10670130, HPA031718: AB_10610148" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (9.83e-2)" "unprognostic (2.27e-1)" "unprognostic (7.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (8.50e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "unprognostic (8.74e-2)" PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2641.0;salivary gland: 1645.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 8805.9;Intestinal goblet cells: 2822.9;Paneth cells: 2841.8;Proximal enterocytes: 1621.1;Undifferentiated cells: 3386.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 28.8;colorectal cancer: 31.1;Gastric cancer: 56.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" NA NA 1300000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "CAB009454: AB_2164819, HPA006154: AB_1855370, HPA012012: AB_1855371" "prognostic favorable (1.22e-5)" "unprognostic (7.42e-2)" "unprognostic (4.78e-3)" "prognostic favorable (2.57e-4)" "unprognostic (2.31e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (2.13e-1)" "prognostic favorable (5.08e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (6.92e-3)" "unprognostic (3.39e-2)" PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322115-120327779 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1519 "pancreas: 117705.6" "Group enriched" "Detected in some" 25 "Exocrine glandular cells: 5496.1;Respiratory ciliated cells: 6986.7" "Cancer enriched" "Detected in many" 185 "pancreatic cancer: 763.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Pancreas - Exocrine glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" NA NA 3900000 "Cluster 48: NK-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 6: BEWO - Unknown function" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA047822: AB_2680169, HPA060803: AB_2684369" "unprognostic (1.28e-4)" "unprognostic (6.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.86e-2)" "unprognostic (2.74e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.80e-4)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (3.60e-1)" "unprognostic (8.61e-4)" PM20D1 "Cps1, FLJ32569" ENSG00000162877 "Peptidase M20 domain containing 1" Q6GTS8 1 205828025-205850132 "Enzymes, Predicted secreted proteins" "Lipid metabolism" "Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pancreas: 78.0;skin 1: 33.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.1;Exocrine glandular cells: 5.1;Gastric mucus-secreting cells: 4.8;Inhibitory neurons: 3.4;Proximal tubular cells: 3.7;Respiratory ciliated cells: 9.8" "Cancer enriched" "Detected in some" 32 "urothelial cancer: 30.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA 3300000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 20: Airway & Pancreas - Proteolysis" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (4.83e-1)" "unprognostic (4.08e-3)" "unprognostic (1.17e-3)" "unprognostic (3.11e-1)" "unprognostic (1.20e-1)" "unprognostic (5.50e-2)" "unprognostic (5.81e-2)" "unprognostic (4.57e-2)" "unprognostic (7.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (1.68e-2)" PNLIP PL ENSG00000175535 "Pancreatic lipase" P16233 10 116545931-116567855 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2058 "pancreas: 444687.5" "Cell type enriched" "Detected in some" 12 "Respiratory ciliated cells: 16562.8" "Cancer enriched" "Detected in some" 4854 "pancreatic cancer: 2731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA062430, HPA062494" Enhanced "Secreted to digestive system" NA NA 14000000 "Cluster 25: Pancreas - Digestion" "Cluster 33: Skin cancer - Membrane components" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA062430: AB_2684761, HPA062494: AB_2684782" "unprognostic (2.05e-2)" "unprognostic (4.46e-2)" PNLIPRP1 PLRP1 ENSG00000187021 "Pancreatic lipase related protein 1" P54315 10 116590385-116609175 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2343 "pancreas: 10825.1" "Cell type enriched" "Detected in some" 4 "Respiratory ciliated cells: 952.2" "Cancer enriched" "Detected in single" 476 "pancreatic cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 340000 "Cluster 25: Pancreas - Digestion" "Cluster 51: Myeloma - Humoral immune response" "Cluster 20: Airway & Pancreas - Proteolysis" "unprognostic (1.21e-1)" "unprognostic (4.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.76e-2)" "unprognostic (1.41e-1)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" PRAP1 UPA ENSG00000165828 "Proline rich acidic protein 1" Q96NZ9 10 133347368-133352683 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 1135.4;liver: 675.2" "Cell type enriched" "Detected in some" 16 "Proximal enterocytes: 12421.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 348.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 75.9;Gastric cancer: 42.0;liver cancer: 32.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "HPA038713, HPA052451" Supported "Secreted to digestive system" NA NA 210000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA038713: AB_10673117, HPA052451: AB_2681839" "unprognostic (1.63e-3)" "unprognostic (1.79e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (8.90e-2)" "unprognostic (3.60e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (4.35e-3)" "unprognostic (4.91e-2)" "unprognostic (8.23e-3)" "unprognostic (2.25e-1)" "unprognostic (3.15e-1)" "unprognostic (2.92e-2)" "unprognostic (2.22e-3)" PRB1 "PM, PMF, PMS, PRB1L, PRB1M" ENSG00000251655 "Proline rich protein BstNI subfamily 1" 12 11351823-11395566 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 2529 "salivary gland: 16328.6" "Cell type enriched" "Detected in some" 39 "Serous glandular cells: 8164.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 21: Serous glandular cells - Salivary secretion" PRB2 "cP7, PRPPRB1, Ps" ENSG00000121335 "Proline rich protein BstNI subfamily 2" P02812 12 11391540-11501041 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 952 "salivary gland: 12081.4" "Cell type enriched" "Detected in some" 41 "Serous glandular cells: 5454.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 25000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 1: Non-specific - Nucleosome assembly" "Cluster 21: Serous glandular cells - Salivary secretion" "unprognostic (1.36e-1)" "unprognostic (1.01e-2)" "unprognostic (2.61e-1)" "unprognostic (2.07e-2)" "unprognostic (9.21e-2)" "unprognostic (5.51e-3)" "unprognostic (1.97e-4)" "unprognostic (1.51e-1)" PRB3 PRG ENSG00000197870 "Proline rich protein BstNI subfamily 3" Q04118 12 11265924-11269805 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1919 "salivary gland: 14225.0" "Cell type enriched" "Detected in some" 40 "Serous glandular cells: 84124.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0;lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" NA NA 27000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: BEWO - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" "unprognostic (4.12e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-1)" "unprognostic (7.46e-3)" "unprognostic (4.12e-2)" "unprognostic (9.65e-2)" "unprognostic (1.94e-2)" "unprognostic (8.27e-2)" "unprognostic (9.98e-2)" "unprognostic (2.35e-1)" "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" PRB4 ENSG00000230657 "Proline rich protein BstNI subfamily 4" 12 11307077-11310436 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 206 "salivary gland: 3664.2" "Cell type enriched" "Detected in some" 37 "Serous glandular cells: 32508.1" "Group enriched" "Detected in some" 10 "lung cancer: 2.0;melanoma: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: Serous glandular cells - Salivary secretion" "unprognostic (1.05e-1)" "unprognostic (8.25e-2)" PRH2 Pr ENSG00000134551 "Proline rich protein HaeIII subfamily 2" P02810 12 10929236-10934845 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 909 "salivary gland: 23048.6" "Cell type enriched" "Detected in some" 36 "Serous glandular cells: 21090.2" "Cancer enriched" "Detected in some" 11 "head and neck cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" NA NA 21000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 52: Spermatids - Smell perception" "Cluster 21: Serous glandular cells - Salivary secretion" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (3.65e-2)" "unprognostic (3.59e-1)" "unprognostic (1.25e-1)" "unprognostic (5.52e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.01e-2)" "unprognostic (7.37e-2)" "unprognostic (1.63e-5)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (4.26e-1)" "unprognostic (3.43e-2)" PRR27 C4orf40 ENSG00000187533 "Proline rich 27" Q6MZM9 4 70133616-70176799 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 959 "salivary gland: 1106.3" "Cell type enriched" "Detected in some" 28 "Serous glandular cells: 873.7" "Cancer enriched" "Detected in single" 10 "breast cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA036150, HPA036151" Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 65: Breast cancer - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA036150: AB_10673001, HPA036151: AB_2674971" "unprognostic (9.52e-2)" PRR4 "LPRP, PROL4" ENSG00000111215 "Proline rich 4" Q16378 12 10845849-10849475 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "salivary gland: 6616.8" "Cell type enriched" "Detected in some" 11 "Serous glandular cells: 1619.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "skin cancer: 6.7" "Skin - Eccrine sweat gland cells" HPA042133 Supported "Secreted to digestive system" NA NA 14000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 33: Skin cancer - Membrane components" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA042133: AB_10793979" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.35e-2)" "unprognostic (1.74e-2)" "unprognostic (1.99e-1)" "unprognostic (5.03e-2)" "unprognostic (3.01e-3)" "unprognostic (3.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.23e-1)" "unprognostic (3.19e-2)" "unprognostic (1.09e-2)" "unprognostic (3.57e-6)" "unprognostic (2.81e-2)" "unprognostic (9.15e-2)" "unprognostic (1.21e-1)" "unprognostic (2.15e-2)" PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1923 "pancreas: 341429.7" "Group enriched" "Detected in some" 81 "Exocrine glandular cells: 14360.0;Respiratory ciliated cells: 43342.5" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 25.8" "Pancreas - Exocrine glandular cells" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 100000000000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: Non-specific - Unknown function" "Cluster 20: Airway & Pancreas - Proteolysis" Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavorable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.12e-1)" PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 452 "pancreas: 239420.0" "Group enriched" "Detected in some" 10 "Exocrine glandular cells: 35981.0;Respiratory ciliated cells: 18695.1" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 4.1;T-reg: 2.9" "Group enriched" "Detected in many" 8 "granulocytes: 4.1;T-cells: 2.9" "Cancer enhanced" "Detected in many" "Myeloma: 200.1;pancreatic cancer: 65.0" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 890000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 25: Pancreas - Digestion" "Cluster 44: Myeloma - Humoral immune response" "Cluster 20: Airway & Pancreas - Proteolysis" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "prognostic favorable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.5;esophagus: 388.6;vagina: 134.2" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 79.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" NA NA 8700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750679-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 268 "pancreas: 31113.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 939.1;Exocrine glandular cells: 774.5;Paneth cells: 538.9;Proximal enterocytes: 1122.3;Respiratory ciliated cells: 1542.6" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 104 "basophil: 158.7" "Lineage enriched" "Detected in many" 104 "granulocytes: 158.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 90.2;prostate cancer: 92.3" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 700000000 "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 20: Airway & Pancreas - Proteolysis" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" REG1A "PSP, PSPS, PSPS1, PTP, REG" ENSG00000115386 "Regenerating family member 1 alpha" P05451 2 79120362-79123409 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 103906.5" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 47467.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 1268.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 89 "breast cancer: 102.9;colorectal cancer: 75.0;Gastric cancer: 57.6;Rhabdoid: 133.8" "CAB025138, HPA045549, HPA045579" Enhanced "Secreted to digestive system" NA NA 68000000 "Cluster 25: Pancreas - Digestion" "Cluster 65: Breast cancer - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" "CAB025138: , HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (1.89e-1)" "unprognostic (2.91e-2)" "unprognostic (3.39e-1)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.52e-2)" "unprognostic (3.54e-3)" "unprognostic (5.53e-2)" "unprognostic (5.54e-2)" REG1B "PSPS2, REGH, REGI-BETA, REGL" ENSG00000172023 "Regenerating family member 1 beta" P48304 2 79085023-79088019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 39745.3" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 14335.7" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 201.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.6" "HPA045549, HPA045579" Supported "Secreted to digestive system" NA NA 32000000 "Cluster 25: Pancreas - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 74: Pancreatic cells - Mixed function" "HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (4.08e-1)" "unprognostic (1.09e-1)" "unprognostic (3.51e-3)" "unprognostic (9.20e-2)" REG3A "HIP, PAP, PAP1, PBCGF, REG-III, REG3" ENSG00000172016 "Regenerating family member 3 alpha" Q06141 2 79157003-79159753 "Plasma proteins, Predicted secreted proteins, Transporters" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 61 "intestine: 6743.6;pancreas: 12212.2" "Group enriched" "Detected in some" 5 "Exocrine glandular cells: 6317.3;Undifferentiated cells: 5268.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 710.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "colorectal cancer: 7.7" "HPA047894, HPA048334, HPA060705" Supported Approved Cytosol "Secreted to digestive system" NA NA 23000000 "Cluster 25: Pancreas - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (2.43e-2)" "unprognostic (2.12e-1)" "unprognostic (3.62e-2)" "unprognostic (1.42e-1)" REG3G "LPPM429, PAP1B, UNQ429" ENSG00000143954 "Regenerating family member 3 gamma" Q6UW15 2 79025686-79028505 "Predicted secreted proteins" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "pancreas: 3517.1" "Group enriched" "Detected in some" 7 "Exocrine glandular cells: 90.4;Proximal enterocytes: 49.2;Respiratory ciliated cells: 184.1" "Cancer enriched" "Detected in many" 13 "pancreatic cancer: 71.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047894, HPA048334, HPA060705" Uncertain Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 33: Skin cancer - Membrane components" "Cluster 20: Airway & Pancreas - Proteolysis" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (3.29e-1)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (8.82e-2)" "unprognostic (7.20e-3)" "unprognostic (5.64e-2)" REG4 "GISP, REG-IV, RELP" ENSG00000134193 "Regenerating family member 4" Q9BYZ8 1 119794017-119811580 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 662.5" "Group enriched" "Detected in some" 47 "Enteroendocrine cells: 7693.9;Intestinal goblet cells: 4397.5" "Group enriched" "Detected in many" 21 "colorectal cancer: 180.6;pancreatic cancer: 215.1;stomach cancer: 162.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive CD8 T-cell: 24.6" "Lineage enriched" "Detected in single" 101 "T-cells: 24.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 110.0;Esophageal cancer: 125.6;Gastric cancer: 171.9" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025867, HPA046555" Enhanced "Secreted to digestive system" NA NA 460000 "Cluster 32: T-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 55: Endocrine cells - Hormone signaling" "CAB025867: , HPA046555: AB_2679696" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (2.86e-3)" "unprognostic (2.57e-1)" "unprognostic (6.52e-2)" "unprognostic (6.20e-3)" "unprognostic (1.11e-1)" "unprognostic (1.64e-2)" "unprognostic (7.10e-2)" "unprognostic (7.85e-2)" "unprognostic (2.99e-1)" "unprognostic (5.12e-3)" "unprognostic (8.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-3)" RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 785.5;Alveolar cells type 1: 1375.7;Alveolar cells type 2: 1076.0;Gastric mucus-secreting cells: 776.3;Hofbauer cells: 1667.8;Macrophages: 1146.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 76.3;pancreatic cancer: 63.3;skin cancer: 66.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Pancreas - Exocrine glandular cells, Skeletal muscle - Macrophages, Testis - Sertoli cells, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: Non-specific - Unknown function" "Cluster 69: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" RNASE8 RAE2 ENSG00000173431 "Ribonuclease A family member 8" Q8TDE3 14 21057822-21058455 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 229 "salivary gland: 54.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: Serous glandular cells - Salivary secretion" SERPINI2 "MEPI, PANCPIN, PI14, TSA2004" ENSG00000114204 "Serpin family I member 2" O75830 3 167441789-167479004 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 133 "pancreas: 1370.0" "Cell type enhanced" "Detected in some" "Astrocytes: 36.4;Exocrine glandular cells: 25.5;Respiratory ciliated cells: 109.4" "Cancer enriched" "Detected in some" 6 "pancreatic cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.1" "Kidney - Podocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 8.7" "Secreted to digestive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 20: Airway & Pancreas - Proteolysis" "unprognostic (1.88e-2)" "unprognostic (2.23e-3)" "unprognostic (1.14e-1)" "unprognostic (5.27e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "unprognostic (2.04e-1)" "unprognostic (3.13e-1)" "unprognostic (1.76e-5)" "unprognostic (5.35e-2)" "unprognostic (4.16e-2)" SMR3A "PBI, PRL5, PROL5" ENSG00000109208 "Submaxillary gland androgen regulated protein 3A" Q99954 4 70360760-70367158 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "salivary gland: 59.8" "Group enriched" "Detected in some" 30 "Club cells: 2.3;Serous glandular cells: 6.8" "Cancer enhanced" "Detected in some" "breast cancer: 0.7;liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044567 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA044567: AB_10796114" "unprognostic (2.06e-1)" SMR3B "P-B, PRL3, PROL3" ENSG00000171201 "Submaxillary gland androgen regulated protein 3B" P02814 4 70370093-70390244 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 946 "salivary gland: 217144.9" "Cell type enriched" "Detected in some" 42 "Serous glandular cells: 34863.8" "Cancer enriched" "Detected in some" 22 "breast cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "thyroid cancer: 43.4" "Testis - Late spermatids" "Secreted to digestive system" NA NA 1900000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 21: Serous glandular cells - Salivary secretion" "unprognostic (3.72e-1)" SPINK1 "PCTT, PSTI, Spink3, TATI" ENSG00000164266 "Serine peptidase inhibitor Kazal type 1" P00995 5 147824572-147831671 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "pancreas: 53063.4" "Cell type enriched" "Detected in many" 6 "Exocrine glandular cells: 28651.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 513.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 202.1;liver cancer: 257.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026366, HPA027498" Enhanced "Secreted to digestive system" NA NA 8000000 "Cluster 25: Pancreas - Digestion" "Cluster 39: Non-specific - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" "CAB026366: , HPA027498: AB_10603115" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (9.96e-3)" "unprognostic (3.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.79e-4)" "unprognostic (8.34e-3)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "unprognostic (1.88e-1)" "unprognostic (3.82e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.44e-7)" "unprognostic (7.98e-2)" "unprognostic (2.07e-1)" "prognostic favorable (2.15e-5)" SPINK4 "MGC133107, PEC-60" ENSG00000122711 "Serine peptidase inhibitor Kazal type 4" O60575 9 33218365-33248567 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 980.5" "Cell type enriched" "Detected in some" 24 "Intestinal goblet cells: 9718.2" "Group enriched" "Detected in many" 20 "colorectal cancer: 237.5;pancreatic cancer: 269.7;stomach cancer: 111.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 1.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.8" "Cancer enriched" "Detected in many" 6 "colorectal cancer: 183.2" "Colon - Colon enterocytes" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in single" HPA007286 Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Secreted to digestive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "Golgi apparatus, Vesicles" Nucleoplasm "HPA007286: AB_1080083" "unprognostic (3.49e-2)" "unprognostic (2.32e-1)" "prognostic favorable (8.85e-5)" "unprognostic (3.09e-4)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (9.66e-2)" "unprognostic (2.43e-1)" "unprognostic (1.24e-1)" "unprognostic (3.25e-1)" "unprognostic (2.42e-3)" STATH STR ENSG00000126549 Statherin P02808 4 69995966-70002570 "Plasma proteins, Predicted secreted proteins, Transporters" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 925 "salivary gland: 9143.2" "Cell type enriched" "Detected in some" 37 "Serous glandular cells: 142948.7" "Group enriched" "Detected in some" 14 "head and neck cancer: 3.5;lung cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Sarcoma: 2.4" HPA044569 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA044569: AB_10966146" "unprognostic (2.00e-2)" TFF1 "BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2" ENSG00000160182 "Trefoil factor 1" P04155 21 42362282-42366535 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "stomach 1: 7973.0" "Cell type enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 11089.9" "Group enriched" "Detected in many" 10 "breast cancer: 402.1;colorectal cancer: 268.3;pancreatic cancer: 805.7;stomach cancer: 744.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "breast cancer: 1206.5" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002170, HPA003425" Enhanced "Secreted to digestive system" NA NA 950000 "Cluster 4: Stomach - Digestion" "Cluster 65: Breast cancer - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" "CAB002170: AB_563985, HPA003425: AB_1848260" "prognostic favorable (5.00e-4)" "unprognostic (8.81e-3)" "unprognostic (9.82e-2)" "prognostic favorable (5.67e-4)" "unprognostic (2.42e-1)" "unprognostic (1.72e-3)" "unprognostic (8.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.52e-1)" "unprognostic (6.62e-2)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (7.72e-3)" "unprognostic (1.07e-1)" TFF2 SML1 ENSG00000160181 "Trefoil factor 2" Q03403 21 42346357-42350997 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 6852.1" "Group enriched" "Detected in some" 61 "Cholangiocytes: 2388.6;Gastric mucus-secreting cells: 6746.0" "Group enriched" "Detected in many" 11 "pancreatic cancer: 320.9;stomach cancer: 244.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Gastric cancer: 69.2;pancreatic cancer: 66.5;prostate cancer: 19.4" "Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025834, HPA036705" Enhanced "Secreted to digestive system" NA NA 890000 "Cluster 4: Stomach - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 58: Gastric mucus-secreting cells - Digestion" "CAB025834: , HPA036705: AB_2675263" "unprognostic (3.95e-2)" "unprognostic (9.87e-2)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.89e-2)" "unprognostic (5.55e-2)" "unprognostic (1.27e-9)" "unprognostic (1.99e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-1)" "unprognostic (5.26e-3)" ZG16 "hZG16, JCLN, JCLN1, ZG16A" ENSG00000174992 "Zymogen granule protein 16" O60844 16 29778256-29782973 "Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "intestine: 479.5" "Cell type enriched" "Detected in some" 29 "Intestinal goblet cells: 44155.5" "Cancer enriched" "Detected in some" 6 "colorectal cancer: 21.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Liver - Hepatocytes, Testis - Early spermatids" "Not detected" "Not detected" "HPA052066, HPA052512" Enhanced "Secreted to digestive system" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA052066: AB_2681716, HPA052512: AB_2681857" "unprognostic (1.64e-2)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (8.20e-2)" "unprognostic (3.50e-2)" "unprognostic (1.93e-2)" "unprognostic (5.14e-2)" "unprognostic (1.65e-1)" "unprognostic (7.77e-2)" "unprognostic (3.27e-1)" "unprognostic (2.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" ZG16B "HRPE773, JCLN2, PRO1567" ENSG00000162078 "Zymogen granule protein 16B" Q96DA0 16 2830169-2839585 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 717 "salivary gland: 63926.2" "Cell type enriched" "Detected in many" 7 "Serous glandular cells: 23485.0" "Cancer enhanced" "Detected in many" "prostate cancer: 47.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.3;intermediate monocyte: 11.4;non-classical monocyte: 7.4" "Lineage enriched" "Detected in many" 7 "monocytes: 11.4" "Cancer enhanced" "Detected in many" "breast cancer: 17.8;prostate cancer: 24.1" "Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "HPA041125, HPA053549" Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 690000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 65: Breast cancer - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" Vesicles Nucleoplasm "HPA041125: AB_10794264, HPA053549: AB_2682184" "unprognostic (5.29e-2)" "unprognostic (2.71e-1)" "unprognostic (4.37e-2)" "prognostic favorable (3.48e-6)" "unprognostic (1.39e-3)" "unprognostic (1.94e-2)" "unprognostic (2.34e-3)" "unprognostic (4.13e-2)" "unprognostic (1.01e-1)" "unprognostic (3.45e-3)" "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.17e-1)" "unprognostic (1.04e-1)" "unprognostic (8.33e-2)"