Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
CCT8	"C21orf112, Cctq, PRED71"	ENSG00000156261	"Chaperonin containing TCP1 subunit 8"	P50990	21	29055805-29073797	"Plasma proteins, Predicted intracellular proteins"		Chaperone		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA018520, HPA021051, HPA029426"	Enhanced		Approved	"Nucleoplasm,Intermediate filaments,Cytosol"		No	No		1100000	"Cluster 44: Non-specific - Transcription"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 32: Myeloid leukemia - Oxygen transport"	"Cluster 18: Non-specific - Mixed function"	"Intermediate filaments"	"Nucleoplasm, Cytosol"	"HPA018520: AB_1846204, HPA021051: AB_1846205, HPA029426: AB_10601796"	"unprognostic (3.41e-3)"	"unprognostic (2.75e-2)"	"unprognostic (2.40e-3)"	"unprognostic (1.62e-1)"	"unprognostic (1.25e-1)"	"unprognostic (4.25e-3)"	"prognostic unfavorable (1.56e-5)"	"unprognostic (8.78e-2)"	"unprognostic (1.37e-1)"	"unprognostic (3.09e-1)"	"unprognostic (1.02e-2)"	"unprognostic (2.91e-1)"	"unprognostic (3.01e-2)"	"unprognostic (8.26e-2)"	"unprognostic (3.50e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.57e-1)"
DES	"CMD1I, CSM1, CSM2"	ENSG00000175084	Desmin	P17661	2	219418377-219426734	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"		"Muscle protein"	"Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 13020.7;intestine: 8627.2;skeletal muscle: 16532.0"	"Group enriched"	"Detected in many"	7	"Cardiomyocytes: 1169.7;Skeletal myocytes: 4291.5"	"Cancer enhanced"	"Detected in all"		"prostate cancer: 562.1;stomach cancer: 400.2"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enriched"	"Detected in some"	13	"Sarcoma: 122.1"	"Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells"	"Low region specificity"	"Detected in many"			"Region enriched"	"Detected in many"	5	"midbrain: 29.5"	"CAB000034, HPA018803"	Enhanced		Supported	"Intermediate filaments"		NA	NA		1600000	"Cluster 7: Monocytes - Unknown function"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 42: Sarcoma - Muscle contraction"	"Cluster 15: Smooth muscle cells - Muscle contraction"	"Intermediate filaments"		"CAB000034: , HPA018803: AB_1847616"	"unprognostic (1.75e-1)"	"unprognostic (1.95e-3)"	"unprognostic (3.43e-2)"	"unprognostic (8.76e-2)"	"unprognostic (7.75e-3)"	"unprognostic (6.61e-3)"	"unprognostic (1.55e-1)"	"unprognostic (2.72e-2)"	"unprognostic (4.67e-1)"	"unprognostic (3.84e-2)"	"unprognostic (2.57e-1)"	"unprognostic (7.43e-2)"	"prognostic unfavorable (5.08e-4)"	"unprognostic (3.49e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.22e-1)"	"unprognostic (9.25e-3)"
EPPK1	EPIPL1	ENSG00000261150	"Epiplakin 1"	P58107	8	143857324-143878467	"Plasma proteins, Predicted intracellular proteins"			"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	4	"skin 1: 16.1"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 63.5;Basal keratinocytes: 85.6;Suprabasal keratinocytes: 144.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular)"	"Not detected"	"Not detected"							"HPA066808, HPA067357, HPA069333"	Approved		Enhanced	"Intermediate filaments"		NA	NA		1200000		"Cluster 61: Skin - Cornification"	"Cluster 19: Stomach & Colon cancer - Absorption"	"Cluster 22: Squamous epithelial cells - Keratinization"	"Intermediate filaments"		"HPA066808: AB_2685726, HPA067357: AB_2685826, HPA069333: AB_2686123"	"unprognostic (1.42e-1)"	"unprognostic (9.30e-2)"	"unprognostic (5.89e-2)"	"prognostic unfavorable (5.52e-5)"	"unprognostic (2.85e-2)"	"unprognostic (5.86e-3)"	"unprognostic (4.90e-2)"	"unprognostic (8.73e-2)"	"unprognostic (9.60e-2)"	"unprognostic (2.31e-1)"	"prognostic unfavorable (3.94e-4)"	"unprognostic (1.35e-1)"	"unprognostic (1.97e-3)"	"unprognostic (5.94e-3)"	"unprognostic (4.35e-1)"	"unprognostic (3.68e-3)"	"unprognostic (5.08e-3)"
EVPL	EVPK	ENSG00000167880	Envoplakin	Q92817	17	76004502-76027306	"Predicted intracellular proteins"	Keratinization			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 281.2;skin 1: 147.4;vagina: 101.9"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 42.9;Basal keratinocytes: 40.2;Squamous epithelial cells: 103.7;Suprabasal keratinocytes: 174.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB002220, HPA053969"	Enhanced		Supported	"Intermediate filaments,Cytosol"		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 46: Non-specific - Unknown function"	"Cluster 3: Suprabasal keratinocytes - Cornification"	"Intermediate filaments"	Cytosol	"CAB002220: AB_563701, HPA053969: AB_2682326"	"unprognostic (2.10e-1)"	"unprognostic (1.58e-1)"	"unprognostic (1.41e-1)"	"unprognostic (4.21e-1)"	"unprognostic (1.05e-2)"	"unprognostic (1.87e-2)"	"unprognostic (1.70e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.94e-1)"	"unprognostic (1.44e-1)"	"unprognostic (7.40e-3)"	"unprognostic (2.64e-1)"	"unprognostic (2.40e-2)"	"unprognostic (2.31e-1)"	"unprognostic (3.47e-1)"	"unprognostic (7.93e-2)"	"unprognostic (3.09e-2)"
GFAP	FLJ45472	ENSG00000131095	"Glial fibrillary acidic protein"	P14136	17	44903159-44916937	"Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Disease variant, Leukodystrophy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	6	"brain: 13076.3"	"Cell type enriched"	"Detected in some"	5	"Astrocytes: 370.1"	"Cancer enriched"	"Detected in some"	368	"glioma: 2468.0"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"neutrophil: 6.2"	"Group enriched"	"Detected in many"	5	"granulocytes: 6.2;NK-cells: 1.7"	"Cancer enriched"	"Detected in all"	51	"Brain cancer: 186.9"		"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000039, HPA056030, HPA063513"	Enhanced	Supported	Supported	"Intermediate filaments"		No	No		170000000	"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 70: Brain - Nervous system development"	"Cluster 10: Ovarian & Endometrial cancers - Unknown function"	"Cluster 63: Astrocytes - Nervous system maintenance"	"Intermediate filaments"		"CAB000039: AB_10013382, HPA056030: AB_2683015, HPA063513: AB_2685027"	"unprognostic (1.79e-2)"	"unprognostic (2.74e-1)"	"unprognostic (9.83e-2)"	"unprognostic (2.12e-5)"	"unprognostic (4.08e-1)"	"unprognostic (5.09e-1)"	"unprognostic (1.26e-1)"	"unprognostic (6.53e-2)"	"unprognostic (6.57e-3)"	"unprognostic (7.35e-2)"	"unprognostic (5.86e-2)"	"unprognostic (1.24e-1)"	"unprognostic (7.63e-2)"	"unprognostic (2.75e-5)"	"unprognostic (1.49e-1)"	"unprognostic (1.66e-1)"	"unprognostic (1.64e-1)"
KRT13	"CK13, K13, MGC161462, MGC3781"	ENSG00000171401	"Keratin 13"	P13646	17	41500981-41505705	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 40925.1;vagina: 13409.3"	"Group enriched"	"Detected in many"	4	"Squamous epithelial cells: 20502.7;Suprabasal keratinocytes: 65697.5"	"Group enriched"	"Detected in many"	5	"cervical cancer: 899.2;head and neck cancer: 758.7;urothelial cancer: 504.9"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enriched"	"Detected in many"	6	"cervical cancer: 3951.7"	"Prostate - Urothelial cells"									"CAB000133, HPA030877, HPA069771"	Enhanced		Enhanced	"Intermediate filaments"		NA	NA		680000000		"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 3: Suprabasal keratinocytes - Cornification"	"Intermediate filaments"		"CAB000133: , HPA030877: AB_2673641, HPA069771: AB_2732141"	"unprognostic (1.45e-1)"	"unprognostic (6.23e-2)"	"unprognostic (1.37e-1)"	"unprognostic (2.19e-2)"	"unprognostic (9.30e-5)"	"unprognostic (7.30e-3)"		"unprognostic (1.95e-1)"	"unprognostic (1.77e-1)"	"unprognostic (5.81e-3)"	"prognostic unfavorable (1.02e-4)"	"unprognostic (3.16e-1)"	"prognostic unfavorable (1.45e-6)"	"unprognostic (1.80e-1)"	"unprognostic (2.76e-1)"	"unprognostic (3.04e-2)"	"unprognostic (4.33e-1)"
KRT14	"EBS3, EBS4"	ENSG00000186847	"Keratin 14"	P02533	17	41582279-41586895	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"skin 1: 6940.5"	"Group enriched"	"Detected in many"	6	"Basal keratinocytes: 28554.7;Suprabasal keratinocytes: 10747.1"	"Cancer enriched"	"Detected in many"	5	"head and neck cancer: 5910.5"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enriched"	"Detected in many"	5	"head and neck cancer: 2378.5"	"Breast - Breast myoepithelial cells, Skin - Keratinocyte (other)"	"Not detected"	"Not detected"			"Region enriched"	"Detected in many"	7	"spinal cord: 36.3"	"CAB000134, HPA000452, HPA000539, HPA023040"	Enhanced		Enhanced	"Intermediate filaments"		NA	NA		1600000000		"Cluster 31: Skin - Epidermis development"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 22: Squamous epithelial cells - Keratinization"	"Intermediate filaments"		"CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201"	"prognostic favorable (2.66e-4)"	"unprognostic (1.64e-1)"	"unprognostic (1.01e-2)"	"unprognostic (1.42e-2)"	"unprognostic (1.66e-1)"	"unprognostic (1.02e-2)"		"unprognostic (2.03e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.00e-2)"	"unprognostic (5.74e-3)"	"unprognostic (1.49e-8)"	"unprognostic (8.91e-2)"	"unprognostic (2.00e-1)"	"unprognostic (8.80e-3)"	"unprognostic (1.22e-2)"
KRT15	"CK15, K15, K1CO"	ENSG00000171346	"Keratin 15"	P19012	17	41513745-41522529	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"breast: 419.1;esophagus: 1156.7;skin 1: 1319.5;vagina: 423.3"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 1641.1;Basal respiratory cells: 1142.9;Basal squamous epithelial cells: 8450.6;Squamous epithelial cells: 3518.4"	"Cancer enhanced"	"Detected in many"		"cervical cancer: 178.9"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	6	"cervical cancer: 1216.0;head and neck cancer: 559.1"	"Prostate - Prostate basal glandular cells, Testis - Late spermatids"	"Region enhanced"	"Detected in single"		"white matter: 1.9"	"Not detected"	"Not detected"			"HPA023910, HPA024554"	Enhanced		Supported	"Nucleoplasm,Intermediate filaments"		No	No		480000000		"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 22: Squamous epithelial cells - Keratinization"	"Intermediate filaments"	Nucleoplasm	"HPA023910: AB_1852205, HPA024554: AB_1852207"	"prognostic favorable (4.50e-4)"	"unprognostic (9.14e-2)"	"unprognostic (3.28e-2)"	"unprognostic (1.19e-3)"	"unprognostic (3.57e-2)"	"unprognostic (8.84e-2)"	"unprognostic (6.12e-3)"	"unprognostic (1.70e-1)"	"unprognostic (2.13e-1)"	"unprognostic (8.65e-3)"	"unprognostic (9.91e-3)"	"unprognostic (2.09e-1)"	"unprognostic (2.24e-11)"	"unprognostic (6.91e-3)"	"unprognostic (2.62e-1)"	"unprognostic (1.33e-5)"	"unprognostic (5.35e-2)"
KRT17	PCHC1	ENSG00000128422	"Keratin 17"	Q04695	17	41619442-41624842	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"breast: 382.1;skin 1: 949.4;urinary bladder: 632.2"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 1931.7;Basal respiratory cells: 12085.1;Club cells: 2543.4;Ionocytes: 3922.1;Salivary duct cells: 1857.3;Suprabasal keratinocytes: 1831.6"	"Cancer enhanced"	"Detected in all"		"head and neck cancer: 3317.2"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"cervical cancer: 3850.8;head and neck cancer: 2928.2"	"Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells"	"Not detected"	"Not detected"							"CAB000029, HPA000452, HPA000453, HPA000539, HPA045062"	Enhanced		Enhanced	"Intermediate filaments"		Yes	No		610000000		"Cluster 31: Skin - Epidermis development"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 5: Bronchus - Unknown function"	"Intermediate filaments"		"CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204"	"prognostic favorable (4.44e-4)"	"unprognostic (1.43e-1)"	"unprognostic (1.15e-1)"	"unprognostic (3.65e-3)"	"unprognostic (4.46e-2)"	"unprognostic (4.34e-1)"	"unprognostic (4.36e-3)"	"unprognostic (1.32e-2)"	"unprognostic (2.27e-1)"	"unprognostic (1.29e-1)"	"unprognostic (7.86e-3)"	"unprognostic (1.53e-1)"	"prognostic unfavorable (5.74e-4)"	"unprognostic (1.82e-1)"	"unprognostic (1.77e-1)"	"unprognostic (2.20e-1)"	"unprognostic (3.89e-1)"
KRT19	"CK19, K19, K1CS, MGC15366"	ENSG00000171345	"Keratin 19"	P08727	17	41523617-41528308	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"	"Host-virus interaction"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 889.0;salivary gland: 810.7;urinary bladder: 781.4"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 6952.7;Club cells: 5515.7;Distal enterocytes: 6516.1;Extravillous trophoblasts: 8087.1;Proximal enterocytes: 9013.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in all"		"Gallbladder cancer: 3957.5"	"Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells"	"Not detected"	"Not detected"							"CAB000031, HPA002465"	Enhanced		Supported	"Intermediate filaments"		NA	NA		300000000	"Cluster 40: NK-cells - Unknown function"	"Cluster 37: Intestine - Unknown function"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 74: Pancreatic cells - Mixed function"	"Intermediate filaments"		"CAB000031: AB_2234418, HPA002465: AB_1079179"	"unprognostic (1.09e-1)"	"unprognostic (1.83e-1)"	"unprognostic (3.86e-2)"	"unprognostic (1.59e-2)"	"unprognostic (2.24e-2)"	"unprognostic (1.13e-1)"	"unprognostic (2.29e-1)"	"unprognostic (2.80e-2)"	"unprognostic (3.14e-1)"	"unprognostic (4.86e-2)"	"prognostic unfavorable (6.82e-5)"	"unprognostic (1.90e-2)"	"prognostic unfavorable (2.98e-5)"	"unprognostic (3.52e-2)"	"unprognostic (2.14e-1)"	"unprognostic (3.08e-2)"	"unprognostic (2.35e-2)"
KRT4	"CK4, CYK4, K4"	ENSG00000170477	"Keratin 4"	P19013	12	52806549-52814116	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	9	"esophagus: 19735.6"	"Group enriched"	"Detected in some"	29	"Squamous epithelial cells: 7509.7;Suprabasal keratinocytes: 21955.2"	"Group enriched"	"Detected in many"	5	"cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	5	"cervical cancer: 1905.1;Gallbladder cancer: 1382.4"	"Prostate - Urothelial cells, Skin - Sebaceous gland cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB002154, HPA034881"	Enhanced		Supported	"Intermediate filaments"		NA	NA		600000000		"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 3: Suprabasal keratinocytes - Cornification"	"Intermediate filaments"		"CAB002154: AB_563803, HPA034881: AB_2674370"	"unprognostic (4.04e-1)"	"unprognostic (3.22e-3)"	"unprognostic (5.16e-3)"	"unprognostic (8.52e-3)"		"unprognostic (1.20e-1)"		"unprognostic (2.64e-1)"	"unprognostic (1.84e-1)"	"prognostic unfavorable (3.26e-4)"	"unprognostic (2.85e-3)"	"unprognostic (2.84e-2)"	"unprognostic (2.58e-11)"	"unprognostic (1.64e-1)"	"unprognostic (6.97e-2)"	"unprognostic (1.16e-1)"	"prognostic unfavorable (6.26e-4)"
KRT6A	"CK6C, CK6D, K6C, K6D, KRT6C, KRT6D"	ENSG00000205420	"Keratin 6A"	P02538	12	52487176-52493257	"Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"cervix: 2523.3;esophagus: 7338.5;vagina: 4945.4"	"Cell type enhanced"	"Detected in some"		"Basal keratinocytes: 5655.3;Serous glandular cells: 2866.1;Suprabasal keratinocytes: 12245.0"	"Cancer enhanced"	"Detected in many"		"head and neck cancer: 3892.0"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Gallbladder cancer: 2653.9;head and neck cancer: 1568.8"	"Skin - Outer root sheath cells"									"HPA045697, HPA061168"	Supported		Enhanced	"Intermediate filaments"		NA	NA		4500000000		"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 3: Suprabasal keratinocytes - Cornification"	"Intermediate filaments"		"HPA045697: AB_2679422, HPA061168: AB_2684440"	"unprognostic (8.10e-3)"	"unprognostic (2.11e-1)"	"unprognostic (2.78e-2)"	"unprognostic (1.06e-1)"		"unprognostic (2.45e-1)"		"prognostic unfavorable (1.45e-4)"	"unprognostic (2.43e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.31e-3)"	"unprognostic (1.29e-1)"	"unprognostic (2.89e-9)"	"unprognostic (8.80e-2)"	"unprognostic (7.20e-2)"	"unprognostic (1.72e-1)"	"unprognostic (2.13e-2)"
KRT8	"CARD2, CK8, CYK8, K2C8, K8, KO"	ENSG00000170421	"Keratin 8"	P05787	12	52897187-52949954	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Host-virus interaction"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 1335.5;stomach 1: 800.1"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 10460.1;Ductal cells: 5404.7;Extravillous trophoblasts: 6116.0;Paneth cells: 8637.7;Proximal enterocytes: 7660.4;Syncytiotrophoblasts: 6043.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"plasmacytoid DC: 1.7"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Mesothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells"	"Low region specificity"	"Detected in many"			"Region enriched"	"Detected in all"	10	"spinal cord: 44.0"	"CAB000131, CAB001696, HPA049866"	Enhanced		Supported	"Intermediate filaments"		NA	NA		1700000000	"Cluster 15: NK-cells - Transcription"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 50: Enterocytes - Absorption"	"Intermediate filaments"		"CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923"	"unprognostic (5.72e-2)"	"unprognostic (2.29e-1)"	"unprognostic (2.49e-2)"	"unprognostic (1.52e-1)"	"unprognostic (2.76e-2)"	"unprognostic (4.86e-3)"	"unprognostic (3.10e-2)"	"unprognostic (2.52e-2)"	"unprognostic (1.92e-1)"	"unprognostic (4.58e-1)"	"prognostic unfavorable (1.51e-4)"	"unprognostic (8.99e-2)"	"unprognostic (2.08e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.18e-1)"	"unprognostic (3.68e-1)"	"unprognostic (1.19e-2)"
KRT80	KB20	ENSG00000167767	"Keratin 80"	Q6KB66	12	52168996-52192014	"Plasma proteins, Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	4	"skin 1: 219.1"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 95.1;Ductal cells: 60.6;Exocrine glandular cells: 44.8;Glandular and luminal cells: 33.4;Mucus glandular cells: 46.4;Pancreatic endocrine cells: 32.6;Suprabasal keratinocytes: 33.8;Syncytiotrophoblasts: 52.6"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Pancreas - Ductal cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA077836, HPA077918"			Enhanced	"Intermediate filaments"		No	No		230000000		"Cluster 31: Skin - Epidermis development"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 74: Pancreatic cells - Mixed function"	"Intermediate filaments"		"HPA077836: AB_2686857, HPA077918: AB_2686871"	"prognostic unfavorable (1.05e-4)"	"unprognostic (5.45e-3)"	"unprognostic (5.35e-2)"	"unprognostic (9.19e-3)"	"unprognostic (2.85e-4)"	"unprognostic (6.68e-2)"	"unprognostic (2.06e-3)"	"unprognostic (1.26e-3)"	"unprognostic (5.60e-2)"	"unprognostic (4.06e-2)"	"unprognostic (7.06e-3)"	"unprognostic (1.02e-1)"	"unprognostic (8.79e-3)"	"unprognostic (8.85e-2)"	"unprognostic (2.03e-1)"	"unprognostic (1.51e-1)"	"unprognostic (2.98e-2)"
NEFM	"NEF3, NF-M, NFM"	ENSG00000104722	"Neurofilament medium"	P07197	8	24913758-24919098	"Plasma proteins, Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	8	"brain: 689.9"	"Cell type enhanced"	"Detected in many"		"Bipolar cells: 44.3;Early spermatids: 102.0;Excitatory neurons: 46.0;Horizontal cells: 182.0;Late spermatids: 115.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	6	"Bone cancer: 33.0;Gallbladder cancer: 55.1;Neuroblastoma: 76.9;Rhabdoid: 126.2"	"Colon - Colon enteroendocrine cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids"									"CAB010900, CAB012976, HPA022845, HPA023138"	Enhanced		Enhanced	"Intermediate filaments"		Yes	NA		220000		"Cluster 70: Brain - Nervous system development"	"Cluster 22: Rhabdoid cancers - Neuronal signaling"	"Cluster 9: Neurons - Nervous system development"	"Intermediate filaments"		"CAB010900: AB_477261, CAB012976: AB_2533154, HPA022845: AB_1854399, HPA023138: AB_1854398"	"unprognostic (1.41e-2)"	"unprognostic (1.83e-1)"	"unprognostic (2.59e-2)"	"unprognostic (9.38e-2)"	"unprognostic (5.17e-2)"	"unprognostic (6.32e-3)"		"unprognostic (6.10e-3)"	"unprognostic (2.57e-1)"	"unprognostic (8.55e-3)"	"unprognostic (2.95e-2)"	"unprognostic (1.84e-1)"	"unprognostic (1.69e-2)"	"unprognostic (1.38e-2)"	"unprognostic (1.92e-1)"	"unprognostic (4.76e-2)"	"unprognostic (2.61e-2)"
NES	FLJ21841	ENSG00000132688	Nestin	P48681	1	156668763-156677407	"Plasma proteins, Predicted intracellular proteins"	Neurogenesis	"Developmental protein"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 161.6"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 91.7;Cardiomyocytes: 285.5;Endothelial cells: 111.4;Sertoli cells: 52.5;Smooth muscle cells: 71.7"	"Cancer enhanced"	"Detected in all"		"glioma: 147.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"testis cancer: 340.7"		"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005889, HPA006286, HPA007007, HPA026111, CAB058692"	Enhanced		Enhanced	"Intermediate filaments"		No	No		100000		"Cluster 44: Heart - Cardiac muscle contraction"	"Cluster 42: Sarcoma - Muscle contraction"	"Cluster 66: Endothelial cells - Angiogenesis"	"Intermediate filaments"		"CAB005889: AB_2251301, CAB058692: AB_2665584, HPA006286: AB_2667550, HPA007007: AB_1854381, HPA026111: AB_1854382"	"unprognostic (7.73e-2)"	"unprognostic (2.05e-1)"	"unprognostic (2.80e-2)"	"unprognostic (1.36e-1)"	"unprognostic (6.37e-2)"	"unprognostic (1.54e-1)"	"unprognostic (1.08e-1)"	"unprognostic (4.40e-2)"	"unprognostic (7.56e-2)"	"unprognostic (9.84e-2)"	"unprognostic (4.49e-2)"	"unprognostic (1.24e-1)"	"prognostic unfavorable (8.02e-7)"	"unprognostic (2.87e-1)"	"unprognostic (2.48e-1)"	"unprognostic (6.67e-2)"	"unprognostic (8.11e-3)"
PJA2	"KIAA0438, Neurodap1, RNF131"	ENSG00000198961	"Praja ring finger ubiquitin ligase 2"	O43164	5	109334713-109409974	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Ubl conjugation pathway"	Transferase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA040347, HPA057636"	Supported		Enhanced	"Intermediate filaments"		No	No			"Cluster 14: Monocytes - Unknown function"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 57: Non-specific - Translation"	"Cluster 64: Non-specific - Transcription"	"Intermediate filaments"		"HPA040347: AB_10795631, HPA057636: AB_2683485"	"unprognostic (5.78e-2)"	"unprognostic (1.25e-1)"	"unprognostic (5.48e-3)"	"unprognostic (1.17e-1)"	"unprognostic (2.99e-1)"	"unprognostic (7.83e-2)"	"unprognostic (2.83e-1)"	"unprognostic (4.33e-2)"	"unprognostic (4.84e-2)"	"prognostic unfavorable (8.02e-4)"	"unprognostic (4.46e-2)"	"unprognostic (6.03e-2)"	"unprognostic (5.64e-3)"	"unprognostic (1.47e-3)"	"unprognostic (5.94e-2)"	"unprognostic (7.59e-2)"	"unprognostic (1.00e-2)"
PKN2	"Pak-2, PRK2, PRKCL2, STK7"	ENSG00000065243	"Protein kinase N2"	Q16513	1	88684222-88836255	"Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation"	"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in all"	5	"neutrophil: 80.5"	"Lineage enriched"	"Detected in all"	8	"granulocytes: 80.5"	"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA034861, HPA057913"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol"		Yes	No			"Cluster 1: Neutrophils - Mixed function"	"Cluster 34: Non-specific - Transcription"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 64: Non-specific - Transcription"	"Nucleoplasm, Intermediate filaments"	"Nuclear bodies, Plasma membrane, Centrosome, Cytosol"	"HPA034861: AB_2674363, HPA057913: AB_2732617"	"unprognostic (7.52e-2)"	"unprognostic (1.46e-1)"	"prognostic favorable (5.67e-4)"	"unprognostic (5.95e-2)"	"unprognostic (3.39e-2)"	"unprognostic (2.51e-2)"	"unprognostic (4.64e-3)"	"unprognostic (1.38e-1)"	"unprognostic (4.43e-2)"	"unprognostic (1.27e-2)"	"unprognostic (2.90e-3)"	"unprognostic (1.23e-1)"	"unprognostic (1.51e-2)"	"unprognostic (5.98e-2)"	"unprognostic (2.38e-1)"	"unprognostic (1.01e-2)"	"unprognostic (1.99e-1)"
PLEC	"EBS1, PCN, PLEC1, PLTN"	ENSG00000178209	Plectin	Q15149	8	143915153-143976734	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"		Actin-binding	"Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 256.5"	"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003847, HPA025967, HPA029906"	Enhanced		Supported	"Intermediate filaments,Focal adhesion sites,Cytosol"		NA	NA		7400000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 59: Non-specific - Translation"	"Cluster 25: Non-specific - Basic cellular processes"	"Cluster 74: Pancreatic cells - Mixed function"	"Intermediate filaments, Cytosol"	"Focal adhesion sites"	"CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279"	"unprognostic (1.02e-1)"	"unprognostic (1.37e-3)"	"prognostic unfavorable (4.29e-4)"	"unprognostic (2.09e-2)"	"unprognostic (1.04e-1)"	"unprognostic (1.05e-2)"	"unprognostic (1.76e-3)"	"prognostic unfavorable (5.33e-4)"	"unprognostic (1.72e-3)"	"unprognostic (1.13e-2)"	"unprognostic (2.85e-3)"	"unprognostic (5.48e-2)"	"prognostic unfavorable (7.98e-6)"	"unprognostic (2.30e-1)"	"unprognostic (4.04e-2)"	"unprognostic (6.58e-2)"	"unprognostic (5.58e-3)"
PRKCE		ENSG00000171132	"Protein kinase C epsilon"	Q02156	2	45651345-46187990	"Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins"	"Cell adhesion, Cell cycle, Cell division, Immunity"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 34.5"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 147.9;Excitatory neurons: 389.0;Inhibitory neurons: 519.5;Late spermatids: 479.2;Oligodendrocyte precursor cells: 141.5"	"Low cancer specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1"	"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in all"			"Lung - Endothelial cells, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB001948, HPA008236, HPA044496"	Enhanced	Supported	Supported	"Vesicles,Plasma membrane,Intermediate filaments,Cytosol"		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 58: Brain - Synaptic function"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 32: Neurons - Synaptic function"	"Intermediate filaments, Cytosol"	"Vesicles, Plasma membrane"	"CAB001948: , HPA008236: , HPA044496: AB_2678959"	"unprognostic (1.10e-1)"	"unprognostic (1.78e-1)"	"unprognostic (2.27e-1)"	"prognostic unfavorable (2.42e-4)"	"unprognostic (9.61e-2)"	"unprognostic (5.70e-2)"	"unprognostic (1.51e-1)"	"prognostic favorable (9.62e-4)"	"unprognostic (3.05e-1)"	"unprognostic (6.72e-2)"	"unprognostic (7.49e-3)"	"unprognostic (9.99e-2)"	"prognostic favorable (2.63e-7)"	"unprognostic (1.21e-1)"	"unprognostic (7.11e-2)"	"unprognostic (6.43e-3)"	"unprognostic (2.23e-2)"
PSMD10	p28	ENSG00000101843	"Proteasome 26S subunit, non-ATPase 10"	O75832	X	108084207-108091549	"Predicted intracellular proteins"	Apoptosis	Chaperone		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002920, CAB010434"	Approved		Supported	"Intermediate filaments,Cytosol"		NA	NA		250000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 68: Epididymis - Unknown function"	"Cluster 48: Non-specific - RNA binding"	"Cluster 18: Non-specific - Mixed function"	Cytosol	"Intermediate filaments"	"CAB010434: AB_640866, HPA002920: AB_1079708"	"unprognostic (1.59e-3)"	"unprognostic (4.12e-3)"	"unprognostic (3.83e-1)"	"unprognostic (3.00e-1)"	"unprognostic (4.65e-2)"	"unprognostic (1.50e-2)"	"unprognostic (3.85e-3)"	"unprognostic (2.35e-1)"	"unprognostic (1.44e-1)"	"unprognostic (2.06e-2)"	"unprognostic (4.95e-2)"	"unprognostic (7.37e-3)"	"unprognostic (1.64e-2)"	"unprognostic (1.42e-2)"	"unprognostic (2.09e-1)"	"unprognostic (5.07e-2)"	"unprognostic (1.09e-1)"
S100A8	"60B8AG, CAGA, CFAG, CGLA, MRP8, P8"	ENSG00000143546	"S100 calcium binding protein A8"	P05109	1	153390032-153391073	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity"	Antimicrobial	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 9723.3;Kupffer cells: 12238.3;Squamous epithelial cells: 10710.7;Suprabasal keratinocytes: 41386.1"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 2290.9;head and neck cancer: 2382.0"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	9	"classical monocyte: 26833.7;neutrophil: 52973.6"	"Group enriched"	"Detected in all"	9	"granulocytes: 52973.6;monocytes: 26833.7"	"Group enriched"	"Detected in many"	8	"cervical cancer: 1388.9;head and neck cancer: 849.7"	"Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			"CAB002791, HPA024372"	Enhanced		Supported	"Intermediate filaments,Cytosol"	"Secreted to blood"	NA	NA	10900000	370000000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 3: Suprabasal keratinocytes - Cornification"	"Intermediate filaments"	Cytosol	"CAB002791: , HPA024372: AB_1856536"	"unprognostic (1.98e-1)"	"unprognostic (1.13e-1)"	"unprognostic (3.79e-2)"	"unprognostic (1.58e-2)"	"unprognostic (8.60e-3)"	"unprognostic (9.26e-3)"	"unprognostic (4.92e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.83e-1)"	"unprognostic (6.13e-2)"	"unprognostic (3.77e-2)"	"unprognostic (2.24e-2)"	"prognostic unfavorable (8.94e-7)"	"unprognostic (1.17e-1)"	"unprognostic (8.90e-2)"	"unprognostic (8.27e-2)"	"unprognostic (8.94e-3)"
S100A9	"60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14"	ENSG00000163220	"S100 calcium binding protein A9"	P06702	1	153357854-153361023	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity"	"Antimicrobial, Antioxidant"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 11312.8;Hofbauer cells: 6740.0;Kupffer cells: 13272.6;Serous glandular cells: 7302.9;Suprabasal keratinocytes: 51664.6"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 5468.0;head and neck cancer: 6692.8"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	6	"classical monocyte: 24579.6;neutrophil: 33654.0"	"Group enriched"	"Detected in all"	6	"granulocytes: 33654.0;monocytes: 24579.6"	"Cancer enhanced"	"Detected in many"		"head and neck cancer: 1394.9"	"Breast - Macrophages, Colon - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA004193, CAB009441, CAB080262"	Enhanced		Supported	"Plasma membrane,Intermediate filaments,Cytosol"	"Secreted to blood"	NA	NA	10600000	1200000000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 3: Suprabasal keratinocytes - Cornification"	"Plasma membrane, Intermediate filaments, Cytosol"		"CAB009441: AB_2184420, CAB080262: , HPA004193: AB_1856537"	"unprognostic (1.72e-1)"	"unprognostic (3.33e-2)"	"unprognostic (2.40e-1)"	"unprognostic (3.94e-3)"	"unprognostic (1.36e-2)"	"unprognostic (5.45e-3)"	"prognostic unfavorable (1.13e-6)"	"unprognostic (1.10e-2)"	"unprognostic (4.31e-1)"	"unprognostic (3.06e-1)"	"unprognostic (1.35e-2)"	"unprognostic (5.59e-2)"	"prognostic unfavorable (8.10e-4)"	"unprognostic (1.48e-1)"	"unprognostic (7.52e-2)"	"unprognostic (5.39e-2)"	"unprognostic (1.75e-2)"
SESTD1	"DKFZp434O0515, Solo"	ENSG00000187231	"SEC14 and spectrin domain containing 1"	Q86VW0	2	179101678-179264832	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Glandular and luminal cells: 159.9;Mucus glandular cells: 155.3;Oligodendrocytes: 293.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA058236, HPA077408"	Approved		Enhanced	"Intermediate filaments"		NA	Yes			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 59: Fibroblasts - Metabolism"	"Cluster 14: Endometrium - Transcription regulation"	"Intermediate filaments"		"HPA058236: AB_2732619, HPA077408: AB_2732344"	"unprognostic (2.76e-1)"	"unprognostic (3.55e-2)"	"unprognostic (2.77e-1)"	"unprognostic (2.12e-1)"	"unprognostic (1.78e-2)"	"unprognostic (2.10e-1)"	"prognostic unfavorable (1.88e-4)"	"unprognostic (9.47e-2)"	"unprognostic (1.64e-1)"	"unprognostic (2.59e-1)"	"unprognostic (7.91e-3)"	"unprognostic (9.21e-2)"	"prognostic favorable (2.78e-11)"	"prognostic unfavorable (2.67e-4)"	"unprognostic (3.25e-2)"	"unprognostic (1.25e-1)"	"unprognostic (2.57e-2)"
SYCE1L	MRP2	ENSG00000205078	"Synaptonemal complex central element protein 1 like"	A8MT33	16	77199408-77213215	"Predicted intracellular proteins"	Meiosis			"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"testis: 23.5"	"Cell type enhanced"	"Detected in many"		"Breast glandular cells: 84.2;Undifferentiated cells: 72.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in many"			"Testis - Early spermatids"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA062464, HPA066691"			Enhanced	"Intermediate filaments"		No	No			"Cluster 35: T-regs - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 68: Kidney - Mixed function"	"Cluster 73: Prostatic glandular cells - Transcription"	"Intermediate filaments"		"HPA062464: , HPA066691: AB_2685702"	"unprognostic (5.54e-3)"	"unprognostic (2.15e-1)"	"unprognostic (1.65e-1)"	"prognostic favorable (6.65e-4)"	"unprognostic (1.32e-1)"	"unprognostic (2.32e-1)"	"unprognostic (3.48e-2)"	"unprognostic (2.00e-3)"	"unprognostic (6.28e-3)"	"unprognostic (1.02e-1)"	"unprognostic (7.48e-2)"	"unprognostic (5.13e-2)"	"prognostic unfavorable (2.11e-5)"	"unprognostic (9.27e-2)"	"unprognostic (4.27e-1)"	"unprognostic (2.68e-2)"	"unprognostic (1.73e-2)"
SYNM	"DMN, KIAA0353, SYN"	ENSG00000182253	Synemin	O15061	15	99098217-99135593	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 594.1;skeletal muscle: 624.7;urinary bladder: 406.3"	"Cell type enhanced"	"Detected in many"		"Breast myoepithelial cells: 120.3;Cardiomyocytes: 634.8;Muller glia cells: 125.3;Skeletal myocytes: 228.6;Smooth muscle cells: 96.2"	"Cancer enhanced"	"Detected in all"		"prostate cancer: 28.8"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in all"		"skin cancer: 65.9"	"Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skin - Smooth muscle cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017192, HPA040066, HPA044200, HPA077856"	Enhanced		Supported	"Intermediate filaments"		NA	NA				"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 33: Skin cancer - Membrane components"	"Cluster 15: Smooth muscle cells - Muscle contraction"	"Intermediate filaments"		"CAB017192: , HPA040066: AB_2676830, HPA044200: AB_2678854, HPA077856: AB_2686861"	"unprognostic (1.04e-2)"	"unprognostic (1.37e-1)"	"unprognostic (3.00e-2)"	"unprognostic (6.10e-2)"	"unprognostic (1.87e-1)"	"unprognostic (1.15e-1)"	"unprognostic (3.52e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.54e-1)"	"unprognostic (1.00e-1)"	"unprognostic (1.34e-2)"	"unprognostic (6.75e-2)"	"unprognostic (3.54e-3)"	"unprognostic (2.80e-2)"	"unprognostic (7.27e-2)"	"unprognostic (5.92e-3)"	"unprognostic (3.26e-3)"
TTC4	"CNS1, FLJ41930, MGC5097"	ENSG00000243725	"Tetratricopeptide repeat domain 4"	O95801	1	54715861-54742657	"Plasma proteins, Predicted intracellular proteins"	"Antiviral defense, Immunity, Innate immunity"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other), Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041608, HPA042459"	Approved		Enhanced	"Intermediate filaments,Cytoplasmic bodies"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 61: Non-specific - Transcription"	"Intermediate filaments"	"Cytoplasmic bodies"	"HPA041608: AB_10794485, HPA042459: AB_10797496"	"unprognostic (4.89e-2)"	"unprognostic (1.81e-1)"	"unprognostic (2.05e-2)"	"unprognostic (8.62e-4)"	"unprognostic (8.91e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.21e-5)"	"unprognostic (1.39e-4)"	"unprognostic (1.51e-2)"	"unprognostic (1.47e-1)"	"unprognostic (3.18e-1)"	"unprognostic (2.42e-3)"	"unprognostic (7.12e-2)"	"unprognostic (2.85e-1)"	"unprognostic (7.79e-2)"	"unprognostic (5.86e-2)"	"unprognostic (1.76e-3)"
VIM		ENSG00000026025	Vimentin	P08670	10	17228241-17237593	"Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Host-virus interaction"		"Cataract, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"granulocytes: 6173.1;Langerhans cells: 5043.7;Leydig cells: 5059.5;Muller glia cells: 8289.1;Schwann cells: 8855.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Heart muscle - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000080, HPA001762, CAB058687"	Enhanced		Supported	"Intermediate filaments"		NA	NA		35000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 75: Myeloid cells - Innate immune response"	"Intermediate filaments"		"CAB000080: AB_2304493, CAB058687: AB_2665570, HPA001762: AB_1080568"	"unprognostic (1.02e-1)"	"unprognostic (2.58e-1)"	"unprognostic (2.87e-2)"	"prognostic favorable (9.75e-6)"	"unprognostic (3.81e-2)"	"unprognostic (2.52e-1)"	"unprognostic (3.21e-1)"	"unprognostic (1.61e-1)"	"unprognostic (1.17e-1)"	"unprognostic (2.05e-1)"	"unprognostic (9.29e-2)"	"unprognostic (5.61e-2)"	"prognostic unfavorable (8.69e-8)"	"unprognostic (1.87e-3)"	"unprognostic (7.32e-2)"	"unprognostic (1.82e-1)"	"unprognostic (9.47e-3)"
ZNF131	"pHZ-10, ZBTB35"	ENSG00000172262	"Zinc finger protein 131"	P52739	5	43065176-43192021	"Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, Repressor"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA007023, HPA027748, HPA074630"	Approved		Enhanced	"Nucleoplasm,Intermediate filaments"		No	No			"Cluster 46: Basophils - DNA binding"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 40: Non-specific - Enzymes"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	"Intermediate filaments"	"HPA007023: AB_2667726, HPA027748: AB_2672374, HPA074630: AB_2686705"	"unprognostic (1.23e-1)"	"unprognostic (8.24e-2)"	"unprognostic (4.70e-2)"	"unprognostic (7.97e-2)"	"unprognostic (8.84e-2)"	"unprognostic (7.18e-2)"	"prognostic unfavorable (1.56e-4)"	"unprognostic (2.52e-1)"	"unprognostic (2.98e-3)"	"unprognostic (1.94e-2)"	"unprognostic (5.83e-2)"	"unprognostic (8.07e-2)"	"unprognostic (2.09e-2)"	"unprognostic (1.47e-2)"	"unprognostic (2.76e-1)"	"unprognostic (3.11e-3)"	"unprognostic (1.46e-2)"
ZNF774	MGC75360	ENSG00000196391	"Zinc finger protein 774"	Q6NX45	15	90352284-90369146	"Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 14.0;Granulosa cells: 44.2;Late spermatids: 13.5"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Smooth muscle cells"									"HPA030839, HPA030840"	Uncertain		Supported	"Intermediate filaments,Cytosol"		No	No			"Cluster 11: Basophils - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 19: Stomach & Colon cancer - Absorption"	"Cluster 17: Granulosa cells - Transcription regulation"	"Intermediate filaments"	Cytosol	"HPA030839: AB_2673630, HPA030840: AB_10602691"	"unprognostic (1.11e-1)"	"unprognostic (2.14e-1)"	"unprognostic (1.38e-1)"	"unprognostic (5.82e-3)"	"unprognostic (3.29e-2)"	"unprognostic (1.35e-1)"	"unprognostic (6.89e-2)"	"unprognostic (9.22e-3)"	"unprognostic (7.82e-2)"	"unprognostic (1.94e-1)"	"unprognostic (3.43e-1)"	"unprognostic (2.89e-2)"	"unprognostic (2.71e-1)"	"unprognostic (5.62e-2)"	"unprognostic (1.27e-1)"	"unprognostic (4.48e-2)"	"unprognostic (4.82e-2)"