Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
DHX57	DDX57	ENSG00000163214	"DExH-box helicase 57"	Q6P158	2	38797729-38875934	"Enzymes, Predicted intracellular proteins"		"Helicase, Hydrolase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in many"	6	"Early spermatids: 114.0;Late spermatids: 355.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA036160	Uncertain		Approved	"Nucleoli,Intermediate filaments,Microtubules,Cytosol"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 68: Epididymis - Unknown function"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 6: Late spermatids - Spermatogenesis"	"Intermediate filaments, Microtubules"	"Nucleoli, Cytosol"	"HPA036160: AB_10670711"	"unprognostic (6.78e-2)"	"unprognostic (3.08e-1)"	"unprognostic (3.49e-2)"	"unprognostic (2.03e-3)"	"unprognostic (3.25e-2)"	"unprognostic (3.43e-1)"	"prognostic unfavorable (3.32e-6)"	"unprognostic (1.75e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.45e-1)"	"unprognostic (7.35e-2)"	"unprognostic (1.82e-2)"	"unprognostic (2.55e-2)"	"unprognostic (1.47e-1)"	"unprognostic (3.88e-2)"	"unprognostic (7.03e-3)"	"unprognostic (1.77e-1)"
MDN1	"KIAA0301, Rea1"	ENSG00000112159	"Midasin AAA ATPase 1"	Q9NU22	6	89642498-89819794	"Plasma proteins, Predicted intracellular proteins"		Chaperone		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 81.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Stomach - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA029666, HPA029667, HPA029668, HPA029669"	Uncertain		Approved	"Nucleoplasm,Nucleoli,Intermediate filaments,Cytosol"		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 15: Non-specific - Protein binding"	"Cluster 16: Non-specific - RNA binding"	"Nucleoli, Cytosol"	"Nucleoplasm, Intermediate filaments"	"HPA029666: AB_10600888, HPA029667: AB_10696207, HPA029668: AB_10669868, HPA029669: AB_10670429"	"unprognostic (2.00e-1)"	"unprognostic (4.46e-2)"	"unprognostic (7.62e-2)"	"unprognostic (2.26e-2)"	"unprognostic (6.14e-3)"	"unprognostic (3.46e-1)"	"unprognostic (6.68e-2)"	"unprognostic (1.40e-1)"	"unprognostic (3.51e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.77e-2)"	"unprognostic (9.07e-2)"	"unprognostic (2.54e-3)"	"unprognostic (6.28e-3)"	"unprognostic (9.22e-2)"	"unprognostic (2.02e-1)"	"unprognostic (6.09e-2)"
PKN2	"Pak-2, PRK2, PRKCL2, STK7"	ENSG00000065243	"Protein kinase N2"	Q16513	1	88684222-88836255	"Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation"	"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in all"	5	"neutrophil: 80.5"	"Lineage enriched"	"Detected in all"	8	"granulocytes: 80.5"	"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA034861, HPA057913"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol"		Yes	No			"Cluster 1: Neutrophils - Mixed function"	"Cluster 34: Non-specific - Transcription"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 64: Non-specific - Transcription"	"Nucleoplasm, Intermediate filaments"	"Nuclear bodies, Plasma membrane, Centrosome, Cytosol"	"HPA034861: AB_2674363, HPA057913: AB_2732617"	"unprognostic (7.52e-2)"	"unprognostic (1.46e-1)"	"prognostic favorable (5.67e-4)"	"unprognostic (5.95e-2)"	"unprognostic (3.39e-2)"	"unprognostic (2.51e-2)"	"unprognostic (4.64e-3)"	"unprognostic (1.38e-1)"	"unprognostic (4.43e-2)"	"unprognostic (1.27e-2)"	"unprognostic (2.90e-3)"	"unprognostic (1.23e-1)"	"unprognostic (1.51e-2)"	"unprognostic (5.98e-2)"	"unprognostic (2.38e-1)"	"unprognostic (1.01e-2)"	"unprognostic (1.99e-1)"
PRKCE		ENSG00000171132	"Protein kinase C epsilon"	Q02156	2	45651345-46187990	"Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins"	"Cell adhesion, Cell cycle, Cell division, Immunity"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 34.5"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 147.9;Excitatory neurons: 389.0;Inhibitory neurons: 519.5;Late spermatids: 479.2;Oligodendrocyte precursor cells: 141.5"	"Low cancer specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1"	"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in all"			"Lung - Endothelial cells, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB001948, HPA008236, HPA044496"	Enhanced	Supported	Supported	"Vesicles,Plasma membrane,Intermediate filaments,Cytosol"		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 58: Brain - Synaptic function"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 32: Neurons - Synaptic function"	"Intermediate filaments, Cytosol"	"Vesicles, Plasma membrane"	"CAB001948: , HPA008236: , HPA044496: AB_2678959"	"unprognostic (1.10e-1)"	"unprognostic (1.78e-1)"	"unprognostic (2.27e-1)"	"prognostic unfavorable (2.42e-4)"	"unprognostic (9.61e-2)"	"unprognostic (5.70e-2)"	"unprognostic (1.51e-1)"	"prognostic favorable (9.62e-4)"	"unprognostic (3.05e-1)"	"unprognostic (6.72e-2)"	"unprognostic (7.49e-3)"	"unprognostic (9.99e-2)"	"prognostic favorable (2.63e-7)"	"unprognostic (1.21e-1)"	"unprognostic (7.11e-2)"	"unprognostic (6.43e-3)"	"unprognostic (2.23e-2)"
RESF1	"C12orf35, FLJ10652, FLJ20696, GET, KIAA1551, UTA2-1"	ENSG00000174718	"Retroelement silencing factor 1"	Q9HCM1	12	31959370-31993107	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"ovary: 73.9"	"Cell type enhanced"	"Detected in many"		"B-cells: 203.7;NK-cells: 184.8;T-cells: 253.3"	"Cancer enhanced"	"Detected in all"		"testis cancer: 65.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 212.8"	"Lineage enriched"	"Detected in all"	5	"granulocytes: 212.8"	"Cancer enriched"	"Detected in all"	4	"testis cancer: 112.9"		"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA013816, HPA015622"	Approved		Supported	"Nucleoli,Nucleoli rim,Intermediate filaments,Cytosol"		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 34: Non-specific - Transcription"	"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 1: T-cells - Immune response"	"Nucleoli, Nucleoli rim"	"Intermediate filaments, Cytosol"	"HPA013816: AB_1848661, HPA015622: AB_1848663"	"unprognostic (7.97e-3)"	"unprognostic (1.69e-1)"	"unprognostic (1.76e-1)"	"unprognostic (8.49e-2)"	"unprognostic (3.21e-1)"	"unprognostic (3.09e-3)"	"unprognostic (2.24e-1)"	"unprognostic (2.19e-1)"	"unprognostic (8.87e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.13e-1)"	"unprognostic (2.90e-2)"	"prognostic unfavorable (5.04e-9)"	"unprognostic (3.83e-1)"	"unprognostic (1.09e-1)"	"unprognostic (2.61e-1)"	"unprognostic (7.26e-3)"
SIK2	"DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2"	ENSG00000170145	"Salt inducible kinase 2"	Q9H0K1	11	111602449-111730855	"Enzymes, Predicted membrane proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 109.8;Excitatory neurons: 214.5;Inhibitory neurons: 129.2;Oligodendrocytes: 181.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA016026, HPA071049"	Approved		Approved	"Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol"		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 59: Fibroblasts - Metabolism"	"Cluster 38: Neurons - Neuronal signaling"	"Nucleoplasm, Vesicles"	"Nuclear speckles, Intermediate filaments, Cytosol"	"HPA016026: AB_1857321, HPA071049: "	"unprognostic (2.35e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.10e-2)"	"unprognostic (1.59e-2)"	"unprognostic (4.81e-2)"	"prognostic favorable (4.93e-4)"	"unprognostic (6.41e-2)"	"unprognostic (1.87e-1)"	"unprognostic (1.40e-2)"	"unprognostic (3.72e-3)"	"unprognostic (9.27e-2)"	"prognostic favorable (1.17e-9)"	"unprognostic (1.23e-1)"	"unprognostic (2.79e-1)"	"unprognostic (2.82e-3)"	"unprognostic (2.13e-2)"
UNC13B	"hmunc13, Munc13-2, UNC13, Unc13h2"	ENSG00000198722	"Unc-13 homolog B"	O14795	9	35161992-35405338	"Predicted intracellular proteins"	Exocytosis			"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Bipolar cells: 79.0;Cone photoreceptor cells: 100.0;Microglial cells: 71.1;Prostatic glandular cells: 110.3;Rod photoreceptor cells: 95.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Prostate - Prostate glandular cells, Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA024493, HPA062300"	Approved		Approved	"Nucleoplasm,Golgi apparatus,Vesicles,Intermediate filaments"		Yes	No				"Cluster 77: Retina - Visual perception"	"Cluster 41: Non-specific - Cilium assembly"	"Cluster 41: Alveolar cells - Lung function"	Vesicles	"Nucleoplasm, Golgi apparatus, Intermediate filaments"	"HPA024493: AB_1858618, HPA062300: AB_2684742"	"unprognostic (9.73e-3)"	"unprognostic (2.33e-1)"	"prognostic favorable (4.96e-4)"	"unprognostic (6.56e-2)"	"unprognostic (9.93e-2)"	"prognostic favorable (8.51e-5)"	"unprognostic (7.64e-2)"	"prognostic favorable (6.59e-5)"	"unprognostic (3.80e-1)"	"unprognostic (1.64e-1)"	"prognostic favorable (3.71e-4)"	"unprognostic (1.74e-1)"	"prognostic favorable (4.34e-11)"	"unprognostic (2.40e-1)"	"unprognostic (1.89e-1)"	"unprognostic (1.48e-1)"	"unprognostic (2.80e-2)"