Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
CENPC	"CENP-C, CENPC1, hcp-4, MIF2"	ENSG00000145241	"Centromere protein C"	Q03188	4	67468762-67545503	"Predicted intracellular proteins"	"Cell cycle, Cell division, Mitosis"	DNA-binding		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA049740, HPA058252"			Supported	"Nucleoplasm,Nuclear bodies,Kinetochore,Midbody"		Yes	Yes			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 21: Non-specific - Transcription"	"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 1: T-cells - Immune response"	"Nuclear bodies, Kinetochore"	"Nucleoplasm, Midbody"	"HPA049740: , HPA058252: AB_2683654"	"unprognostic (4.35e-1)"	"unprognostic (6.41e-3)"	"unprognostic (4.31e-3)"	"unprognostic (7.85e-2)"	"unprognostic (6.31e-2)"	"unprognostic (3.85e-3)"	"unprognostic (6.40e-2)"	"prognostic favorable (9.67e-4)"	"unprognostic (3.22e-2)"	"unprognostic (7.13e-2)"	"unprognostic (8.35e-2)"	"unprognostic (4.32e-2)"	"prognostic favorable (5.63e-4)"	"unprognostic (2.40e-1)"	"unprognostic (1.92e-1)"	"unprognostic (1.15e-1)"	"unprognostic (1.92e-3)"
DSN1	"C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13"	ENSG00000149636	"DSN1 component of MIS12 kinetochore complex"	Q9H410	20	36751791-36773818	"Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division, Chromosome partition, Mitosis"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cytotrophoblasts: 50.4;Spermatocytes: 119.5;Spermatogonia: 63.7;Syncytiotrophoblasts: 53.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002813, HPA030627"	Enhanced		Supported	"Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol"		Yes	Yes			"Cluster 6: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	"Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol"	"HPA002813: AB_1078343, HPA030627: AB_2732460"	"unprognostic (3.60e-2)"	"prognostic favorable (4.49e-4)"	"unprognostic (5.22e-3)"	"unprognostic (1.13e-3)"	"unprognostic (2.00e-1)"	"unprognostic (4.64e-2)"	"prognostic unfavorable (4.16e-5)"	"unprognostic (3.93e-1)"	"unprognostic (9.35e-2)"	"unprognostic (5.51e-2)"	"unprognostic (2.98e-2)"	"unprognostic (7.66e-2)"	"prognostic unfavorable (1.54e-5)"	"unprognostic (6.92e-2)"	"unprognostic (2.53e-1)"	"unprognostic (2.58e-2)"	"unprognostic (2.84e-1)"
INCENP	FLJ31633	ENSG00000149503	"Inner centromere protein"	Q9NQS7	11	62123998-62153169	"Predicted intracellular proteins"	"Cell cycle, Cell division, Chromosome partition, Mitosis"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 20.9"	"Cell type enhanced"	"Detected in many"		"Plasma cells: 15.9;Squamous epithelial cells: 15.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	7	"basophil: 1.2;NK-cell: 1.1"	"Group enriched"	"Detected in many"	7	"granulocytes: 1.2;NK-cells: 1.1"	"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipose progenitor cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013292, HPA051339, HPA070550"	Enhanced		Supported	"Nucleoplasm,Nuclear bodies,Kinetochore,Midbody"		Yes	Yes			"Cluster 15: NK-cells - Transcription"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 40: Plasma cells - Humoral immune response"	"Nuclear bodies, Kinetochore"	"Nucleoplasm, Midbody"	"CAB013292: AB_2533405, HPA051339: AB_2732566, HPA070550: AB_2686279"	"unprognostic (6.31e-2)"	"unprognostic (7.29e-2)"	"unprognostic (1.65e-3)"	"unprognostic (7.35e-2)"	"unprognostic (3.18e-1)"	"unprognostic (1.91e-1)"	"prognostic unfavorable (1.25e-4)"	"prognostic unfavorable (8.58e-4)"	"unprognostic (1.63e-2)"	"unprognostic (4.37e-2)"	"prognostic unfavorable (5.76e-5)"	"unprognostic (1.74e-2)"	"unprognostic (1.08e-3)"	"unprognostic (1.17e-3)"	"unprognostic (1.22e-1)"	"unprognostic (1.36e-1)"	"unprognostic (2.78e-3)"
KLHDC4	DKFZp434G0522	ENSG00000104731	"Kelch domain containing 4"	Q8TBB5	16	87696485-87765992	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Late spermatids: 85.4;NK-cells: 64.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA041665	Approved		Approved	Nucleoli,Kinetochore		Yes	No			"Cluster 27: Non-specific - Gene expression"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 36: Non-specific - Unknown function"	"Cluster 7: NK-cells - Immune response regulation"	Nucleoli	Kinetochore	"HPA041665: AB_10796352"	"unprognostic (2.96e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.28e-3)"	"unprognostic (3.54e-1)"	"unprognostic (2.94e-1)"	"unprognostic (2.26e-2)"	"unprognostic (7.61e-3)"	"unprognostic (6.40e-2)"	"unprognostic (1.20e-1)"	"unprognostic (2.87e-1)"	"prognostic favorable (1.14e-4)"	"unprognostic (3.84e-2)"	"unprognostic (2.73e-2)"	"unprognostic (1.54e-1)"	"unprognostic (4.56e-2)"	"unprognostic (3.88e-1)"	"prognostic favorable (1.69e-4)"
NUF2	"CDCA1, CT106, NUF2R"	ENSG00000143228	"NUF2 component of NDC80 kinetochore complex"	Q9BZD4	1	163266576-163355764	"Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division, Mitosis"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"bone marrow: 28.4;lymphoid tissue: 26.0;testis: 53.5"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 58.5;Extravillous trophoblasts: 32.0;Spermatocytes: 201.9;Spermatogonia: 34.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in single"			"Immune cell enhanced"	"Detected in many"		"T-reg: 4.3"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA059692, HPA076604"			Supported	Nucleoplasm,Kinetochore,Cytosol		Yes	Yes			"Cluster 35: T-regs - Unknown function"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	"Kinetochore, Cytosol"	"HPA059692: AB_2684103, HPA076604: "	"unprognostic (9.41e-2)"	"unprognostic (2.61e-1)"	"unprognostic (2.56e-1)"	"unprognostic (5.32e-3)"	"unprognostic (6.20e-2)"	"unprognostic (3.77e-2)"	"prognostic unfavorable (1.04e-5)"	"prognostic unfavorable (9.16e-4)"	"prognostic unfavorable (4.83e-4)"	"unprognostic (8.45e-2)"	"prognostic unfavorable (9.75e-4)"	"unprognostic (3.70e-2)"	"unprognostic (0.00e+0)"	"unprognostic (9.79e-2)"	"unprognostic (7.88e-2)"	"unprognostic (2.69e-1)"	"unprognostic (5.96e-2)"
SGO1	"NY-BR-85, SGOL1"	ENSG00000129810	"Shugoshin 1"	Q5FBB7	3	20160593-20186206	"Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, Cell division, Chromosome partition, Mitosis"		"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 8.7;lymphoid tissue: 13.0;testis: 6.7"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 33.8;Extravillous trophoblasts: 48.1;Spermatocytes: 70.3;Spermatogonia: 44.0;Undifferentiated cells: 23.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in single"			"Group enriched"	"Detected in many"	5	"basophil: 10.0;memory B-cell: 8.8;naive B-cell: 8.9;plasmacytoid DC: 4.1;T-reg: 2.6"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA035501, HPA069302, HPA069857"	Enhanced		Approved	Nucleoplasm,Kinetochore,Cytosol		Yes	Yes			"Cluster 37: B-cells - Transcription"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	"Kinetochore, Cytosol"	"HPA035501: AB_2732469, HPA069302: , HPA069857: AB_2686214"	"unprognostic (6.87e-3)"	"unprognostic (5.01e-2)"	"unprognostic (2.25e-2)"	"unprognostic (8.93e-3)"	"unprognostic (2.51e-2)"	"unprognostic (4.10e-2)"	"unprognostic (2.55e-6)"	"unprognostic (9.49e-3)"	"unprognostic (2.45e-2)"	"unprognostic (3.69e-2)"	"unprognostic (1.65e-4)"	"unprognostic (1.52e-2)"	"unprognostic (0.00e+0)"	"unprognostic (2.29e-2)"	"unprognostic (4.95e-2)"	"unprognostic (4.14e-1)"	"unprognostic (1.64e-1)"