Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
C12orf66	FLJ32549	ENSG00000174206	"Chromosome 12 open reading frame 66"	Q96MD2	12	64186316-64222296	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA046743, HPA052855"	Uncertain		Supported	"Lysosomes,Cytokinetic bridge"		Yes	No			"Cluster 30: Non-specific - Translation"	"Cluster 35: Non-specific - Unknown function"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 24: Spermatids - Unknown function"	Lysosomes	"Cytokinetic bridge"	"HPA046743: AB_2679782, HPA052855: AB_2681973"	"unprognostic (7.44e-3)"	"unprognostic (2.38e-1)"	"unprognostic (6.20e-2)"	"unprognostic (2.70e-1)"	"unprognostic (2.31e-1)"	"unprognostic (4.62e-2)"	"unprognostic (3.45e-2)"	"unprognostic (2.08e-1)"	"unprognostic (1.15e-1)"	"unprognostic (2.94e-1)"	"unprognostic (1.93e-1)"	"unprognostic (3.60e-1)"	"unprognostic (1.22e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.10e-1)"	"unprognostic (7.46e-2)"	"unprognostic (4.07e-2)"
CLTA	Lca	ENSG00000122705	"Clathrin light chain A"	P09496	9	36190856-36304781	"Plasma proteins, Predicted intracellular proteins, Transporters"	"Cell cycle, Cell division, Mitosis"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Syncytiotrophoblasts: 1282.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002665, HPA050918, HPA054667"	Enhanced		Supported	Vesicles,Endosomes,Lysosomes		NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 35: Non-specific - Unknown function"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 12: Non-specific - Chromatin organization"	"Vesicles, Endosomes, Lysosomes"		"CAB002665: , HPA050918: AB_2681273, HPA054667: AB_2682565"	"prognostic favorable (5.64e-4)"	"unprognostic (7.62e-2)"	"unprognostic (9.22e-2)"	"unprognostic (8.45e-3)"	"unprognostic (1.71e-1)"	"unprognostic (1.92e-1)"	"prognostic unfavorable (9.46e-5)"	"unprognostic (1.42e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.92e-3)"	"unprognostic (7.27e-2)"	"unprognostic (2.15e-1)"	"unprognostic (1.23e-3)"	"unprognostic (5.92e-2)"	"unprognostic (1.56e-1)"	"prognostic favorable (1.01e-4)"	"unprognostic (4.98e-2)"
CLTC	"CLTCL2, Hc"	ENSG00000141367	"Clathrin heavy chain"	Q00610	17	59619689-59696956	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Autophagy, Cell cycle, Cell division, Mitosis"		"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010389, CAB011571, CAB017155, HPA059143"	Approved		Supported	"Endosomes,Lysosomes,Mitotic spindle,Cytosol"		Yes	No		14000000	"Cluster 27: Non-specific - Gene expression"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 12: Non-specific - Chromatin organization"	"Endosomes, Lysosomes"	"Mitotic spindle, Cytosol"	"CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: AB_2683924"	"unprognostic (1.56e-1)"	"prognostic unfavorable (7.35e-4)"	"prognostic favorable (7.65e-4)"	"unprognostic (1.03e-1)"	"unprognostic (2.62e-1)"	"unprognostic (5.23e-3)"	"prognostic unfavorable (5.54e-4)"	"unprognostic (1.11e-1)"	"unprognostic (6.43e-2)"	"unprognostic (1.09e-1)"	"unprognostic (3.34e-2)"	"unprognostic (2.69e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.18e-1)"	"unprognostic (9.22e-2)"	"unprognostic (1.10e-1)"	"prognostic unfavorable (2.02e-4)"
GRN	"CLN11, PCDGF, PGRN"	ENSG00000030582	"Granulin precursor"	P28799	17	44345246-44353106	"Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"		Cytokine	"Neurodegeneration, Neuronal ceroid lipofuscinosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Hofbauer cells: 1448.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	6	"classical monocyte: 2057.5;intermediate monocyte: 1122.4;myeloid DC: 1534.2;neutrophil: 851.2;non-classical monocyte: 548.1;plasmacytoid DC: 1331.9"	"Group enriched"	"Detected in all"	9	"dendritic cells: 1534.2;granulocytes: 851.2;monocytes: 2057.5"	"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Stomach - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008763, CAB019394, HPA028747"	Uncertain		Enhanced	Endosomes,Lysosomes	"Secreted to blood"	NA	NA	138000000	110000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 19: Macrophages - Innate immune response"	Lysosomes	Endosomes	"CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767"	"unprognostic (1.84e-1)"	"unprognostic (2.34e-1)"	"unprognostic (8.38e-3)"	"unprognostic (2.82e-1)"	"prognostic unfavorable (8.78e-4)"	"unprognostic (7.41e-2)"	"unprognostic (3.53e-3)"	"unprognostic (3.57e-1)"	"unprognostic (1.63e-1)"	"unprognostic (2.40e-1)"	"unprognostic (2.24e-2)"	"unprognostic (1.52e-1)"	"unprognostic (6.34e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.43e-1)"	"unprognostic (1.43e-1)"	"unprognostic (1.62e-1)"
HGS	"Hrs, Vps27, ZFYVE8"	ENSG00000185359	"Hepatocyte growth factor-regulated tyrosine kinase substrate"	O14964	17	81683326-81703138	"Plasma proteins, Predicted intracellular proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Late spermatids: 149.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004872, HPA007728"	Uncertain		Supported	Endosomes,Lysosomes,Cytosol		NA	NA		45000	"Cluster 18: Basophils - Vesicular transport"	"Cluster 35: Non-specific - Unknown function"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 51: Late spermatids - Spermatogenesis"	"Endosomes, Lysosomes"	Cytosol	"HPA004872: AB_1079053, HPA007728: AB_1850681"	"unprognostic (6.52e-2)"	"prognostic unfavorable (4.22e-4)"	"unprognostic (4.29e-1)"	"unprognostic (1.31e-2)"	"unprognostic (4.91e-2)"	"unprognostic (1.04e-1)"	"prognostic unfavorable (5.61e-5)"	"unprognostic (5.54e-3)"	"unprognostic (1.09e-1)"	"unprognostic (9.27e-2)"	"unprognostic (5.30e-2)"	"unprognostic (1.27e-1)"	"prognostic unfavorable (4.31e-7)"	"unprognostic (3.69e-1)"	"unprognostic (2.27e-1)"	"unprognostic (1.66e-1)"	"unprognostic (1.45e-1)"
RAB7A	"CMT2B, RAB7"	ENSG00000075785	"RAB7A, member RAS oncogene family"	P51149	3	128693669-128825942	"Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Autophagy, Host-virus interaction, Lipid degradation, Lipid metabolism, Protein transport, Transport"	Hydrolase	"Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Syncytiotrophoblasts: 578.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Macrophages, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006964, CAB037131"	Supported		Supported	Lysosomes		NA	NA		5700000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 59: Non-specific - Translation"	"Cluster 43: Non-specific - Mitochondria"	"Cluster 74: Pancreatic cells - Mixed function"	Lysosomes		"CAB037131: AB_477460, HPA006964: AB_1856015"	"unprognostic (1.99e-2)"	"unprognostic (9.03e-2)"	"unprognostic (1.41e-2)"	"prognostic unfavorable (1.52e-4)"	"unprognostic (1.45e-1)"	"unprognostic (7.82e-2)"	"prognostic unfavorable (9.89e-6)"	"unprognostic (2.15e-2)"	"unprognostic (2.38e-1)"	"unprognostic (3.50e-1)"	"prognostic unfavorable (4.63e-4)"	"unprognostic (4.69e-1)"	"unprognostic (6.73e-3)"	"unprognostic (1.88e-1)"	"unprognostic (1.97e-1)"	"unprognostic (3.03e-3)"	"unprognostic (5.64e-3)"
RPS6KC1	"humS6PKh1, RSKL1"	ENSG00000136643	"Ribosomal protein S6 kinase C1"	Q96S38	1	213051233-213274774	"Enzymes, Predicted intracellular proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 83.5;Excitatory neurons: 269.3;Inhibitory neurons: 147.6;Microglial cells: 98.5;Oligodendrocyte precursor cells: 111.7;Oligodendrocytes: 129.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 16.8"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA026531, HPA031565"	Approved		Supported	Endosomes,Lysosomes		NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 78: Testis - Spermatogenesis"	"Cluster 18: Non-specific - RNA binding"	"Cluster 38: Neurons - Neuronal signaling"	"Endosomes, Lysosomes"		"HPA026531: AB_10601497, HPA031565: AB_2673935"	"unprognostic (3.90e-2)"	"unprognostic (5.90e-2)"	"unprognostic (3.22e-1)"	"unprognostic (4.88e-2)"	"unprognostic (2.42e-1)"	"unprognostic (9.81e-2)"	"unprognostic (1.32e-2)"	"unprognostic (1.64e-1)"	"unprognostic (4.10e-2)"	"unprognostic (3.34e-1)"	"unprognostic (4.18e-1)"	"unprognostic (5.11e-2)"	"prognostic unfavorable (2.70e-4)"	"unprognostic (8.10e-2)"	"unprognostic (5.48e-2)"	"unprognostic (2.98e-2)"	"unprognostic (4.44e-2)"
RPTOR	"KIAA1303, KOG1, Mip1, raptor"	ENSG00000141564	"Regulatory associated protein of MTOR complex 1"	Q8N122	17	80544819-80966371	"Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Host-virus interaction"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 44.6;Excitatory neurons: 69.0;Inhibitory neurons: 64.9;Oligodendrocyte precursor cells: 48.6;Oligodendrocytes: 62.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in all"			"Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013514, HPA064306"	Approved		Supported	Vesicles,Lysosomes,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 59: Non-specific - Translation"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 38: Neurons - Neuronal signaling"	"Vesicles, Lysosomes"	Cytosol	"CAB013514: AB_2533523, HPA064306: AB_2685240"	"unprognostic (5.09e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.79e-1)"	"unprognostic (1.90e-1)"	"unprognostic (1.38e-1)"	"unprognostic (9.75e-2)"	"unprognostic (3.34e-3)"	"unprognostic (1.17e-2)"	"unprognostic (9.63e-2)"	"unprognostic (8.80e-2)"	"unprognostic (4.40e-3)"	"unprognostic (8.46e-2)"	"unprognostic (6.03e-2)"	"unprognostic (1.19e-1)"	"unprognostic (2.90e-1)"	"unprognostic (1.27e-2)"	"unprognostic (1.77e-2)"
SCARB1	"CD36L1, CLA-1, CLA1, SR-BI, SRB1"	ENSG00000073060	"Scavenger receptor class B member 1"	Q8WTV0	12	124776856-124882668	"Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Host-virus interaction"	"Host cell receptor for virus entry, Receptor"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	4	"adrenal gland: 995.8"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 146.9;Granulosa cells: 129.4;Hepatocytes: 150.4;Kupffer cells: 143.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	4	"classical monocyte: 6.2;myeloid DC: 8.9;plasmacytoid DC: 21.0"	"Group enriched"	"Detected in many"	6	"dendritic cells: 21.0;monocytes: 6.2"	"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA066285, CAB070124, HPA072449"	Enhanced		Approved	"Vesicles,Lysosomes,Rods & Rings"		NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 16: Skin cancer - Melanocyte processes"	"Cluster 29: Hepatocytes - Metabolism"	Vesicles	"Lysosomes, Rods & Rings"	"CAB070124: AB_10107658, HPA066285: AB_2685649, HPA072449: AB_2732201"	"unprognostic (9.70e-3)"	"unprognostic (4.94e-3)"	"unprognostic (1.32e-1)"	"unprognostic (4.79e-2)"	"unprognostic (1.65e-3)"	"unprognostic (4.21e-3)"	"prognostic unfavorable (1.83e-5)"	"prognostic unfavorable (4.02e-4)"	"unprognostic (2.30e-1)"	"unprognostic (1.09e-1)"	"unprognostic (1.80e-2)"	"unprognostic (4.99e-2)"	"prognostic unfavorable (1.49e-5)"	"unprognostic (3.50e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.81e-1)"	"unprognostic (4.13e-1)"
SNX1	"HsT17379, MGC8664, SNX1A, Vps5"	ENSG00000028528	"Sorting nexin 1"	Q13596	15	64094123-64146090	"Predicted intracellular proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocytes: 167.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Lung - Alveolar cells type 1, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in single"			"HPA047373, HPA052761"	Approved		Enhanced	Endosomes,Lysosomes		NA	NA		6100000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 68: Epididymis - Unknown function"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 12: Non-specific - Chromatin organization"	"Endosomes, Lysosomes"		"HPA047373: AB_2680018, HPA052761: AB_2681939"	"unprognostic (3.99e-2)"	"unprognostic (8.65e-3)"	"unprognostic (1.96e-1)"	"unprognostic (1.50e-2)"	"unprognostic (7.13e-2)"	"unprognostic (2.73e-1)"	"unprognostic (7.15e-2)"	"unprognostic (6.49e-3)"	"unprognostic (1.53e-1)"	"unprognostic (8.28e-2)"	"unprognostic (2.47e-2)"	"unprognostic (3.26e-1)"	"prognostic favorable (9.88e-6)"	"unprognostic (2.27e-1)"	"unprognostic (3.98e-1)"	"unprognostic (2.59e-2)"	"unprognostic (1.95e-1)"
SNX2		ENSG00000205302	"Sorting nexin 2"	O60749	5	122775079-122834543	"Predicted intracellular proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Extravillous trophoblasts: 275.7;Hofbauer cells: 338.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"memory B-cell: 290.2;naive B-cell: 289.1"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Breast - Fibroblasts, Lung - Macrophages, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037400, HPA077664"	Approved		Enhanced	Endosomes,Lysosomes		NA	NA		150000	"Cluster 37: B-cells - Transcription"	"Cluster 72: Non-specific - Transcription"	"Cluster 57: Non-specific - Translation"	"Cluster 12: Non-specific - Chromatin organization"	Endosomes	Lysosomes	"HPA037400: AB_10670381, HPA077664: "	"unprognostic (9.26e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.86e-2)"	"unprognostic (1.97e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.91e-1)"	"prognostic unfavorable (7.90e-6)"	"unprognostic (1.03e-1)"	"unprognostic (3.86e-2)"	"unprognostic (3.27e-2)"	"unprognostic (4.41e-2)"	"unprognostic (1.60e-1)"	"prognostic favorable (8.76e-7)"	"unprognostic (8.76e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.07e-1)"	"unprognostic (8.59e-2)"
SNX6		ENSG00000129515	"Sorting nexin 6"	Q9UNH7	14	34561093-34630160	"Plasma proteins, Predicted intracellular proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA049374	Approved		Supported	Endosomes,Lysosomes		NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 46: Non-specific - Unknown function"	"Cluster 12: Non-specific - Chromatin organization"	"Endosomes, Lysosomes"		"HPA049374: AB_2680734"	"unprognostic (1.89e-1)"	"unprognostic (6.49e-2)"	"unprognostic (1.46e-1)"	"unprognostic (3.06e-2)"	"unprognostic (1.12e-1)"	"unprognostic (2.36e-3)"	"prognostic unfavorable (1.25e-4)"	"unprognostic (1.23e-1)"	"unprognostic (6.63e-2)"	"unprognostic (1.06e-1)"	"prognostic unfavorable (4.68e-4)"	"unprognostic (1.91e-1)"	"unprognostic (3.48e-2)"	"unprognostic (1.40e-1)"	"unprognostic (1.55e-1)"	"unprognostic (8.82e-2)"	"unprognostic (2.10e-2)"
STX7		ENSG00000079950	"Syntaxin 7"	O15400	6	132445867-132513198	"Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"basophil: 53.6;classical monocyte: 51.6;eosinophil: 49.1;intermediate monocyte: 58.1;memory B-cell: 85.9;myeloid DC: 61.6;naive B-cell: 106.8;neutrophil: 83.2;non-classical monocyte: 61.6;plasmacytoid DC: 73.9"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001467, CAB062564"	Enhanced		Supported	Lysosomes		NA	NA		380000	"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 16: Immune cells - Immune response"	"Cluster 16: Skin cancer - Melanocyte processes"	"Cluster 62: B-cells - B-cell activation"	Lysosomes		"CAB062564: AB_2665605, HPA001467: AB_1857623"	"unprognostic (1.91e-3)"	"unprognostic (1.06e-3)"	"unprognostic (2.67e-2)"	"unprognostic (7.95e-3)"	"unprognostic (1.21e-1)"	"unprognostic (2.04e-1)"	"prognostic unfavorable (1.60e-4)"	"unprognostic (4.52e-2)"	"unprognostic (4.46e-1)"	"unprognostic (4.19e-2)"	"unprognostic (2.84e-1)"	"unprognostic (2.79e-1)"	"unprognostic (1.65e-3)"	"unprognostic (2.16e-1)"	"unprognostic (2.06e-1)"	"unprognostic (1.67e-1)"	"unprognostic (8.42e-2)"
TFRC	"CD71, p90, TFR1"	ENSG00000072274	"Transferrin receptor"	P02786	3	196027183-196082096	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters"	"Endocytosis, Host-virus interaction"	"Host cell receptor for virus entry, Receptor, Transducer"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 254.5"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 455.8;monocytes: 321.5;Syncytiotrophoblasts: 473.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000153, HPA028598"	Enhanced		Supported	Endosomes,Lysosomes	"Secreted to blood"	NA	NA	1310000000	38000000	"Cluster 27: Non-specific - Gene expression"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 19: Macrophages - Innate immune response"	"Endosomes, Lysosomes"		"CAB000153: AB_2533029, HPA028598: AB_10601599"	"unprognostic (2.95e-2)"	"prognostic unfavorable (3.67e-4)"	"unprognostic (2.55e-1)"	"unprognostic (1.48e-2)"	"unprognostic (6.75e-2)"	"unprognostic (7.88e-3)"	"prognostic unfavorable (1.15e-4)"	"unprognostic (6.92e-2)"	"unprognostic (3.30e-3)"	"unprognostic (4.35e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.14e-2)"	"unprognostic (3.63e-3)"	"unprognostic (3.65e-2)"	"unprognostic (1.19e-2)"	"prognostic unfavorable (2.96e-4)"	"unprognostic (2.62e-2)"
TMEM106B	"FLJ11273, MGC33727"	ENSG00000106460	"Transmembrane protein 106B"	Q9NUM4	7	12211270-12243367	"Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	Transport		"Amyotrophic lateral sclerosis, Disease variant, Leukodystrophy, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA058342	Approved		Supported	Endosomes,Lysosomes		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 63: Non-specific - Unknown function"	"Cluster 53: Connective tissue cells - ECM organization"	"Endosomes, Lysosomes"		"HPA058342: AB_2683684"	"unprognostic (5.29e-2)"	"unprognostic (2.34e-2)"	"unprognostic (4.20e-2)"	"unprognostic (6.20e-2)"	"unprognostic (2.73e-1)"	"unprognostic (1.87e-2)"	"unprognostic (3.50e-2)"	"unprognostic (5.89e-2)"	"unprognostic (4.44e-2)"	"unprognostic (1.30e-1)"	"unprognostic (3.01e-3)"	"unprognostic (2.09e-2)"	"unprognostic (1.75e-3)"	"unprognostic (5.52e-2)"	"unprognostic (3.06e-2)"	"unprognostic (2.16e-2)"	"unprognostic (1.70e-1)"
TMEM192	FLJ38482	ENSG00000170088	"Transmembrane protein 192"	Q8IY95	4	165070608-165208549	"Predicted membrane proteins, Transporters"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Prostate - Prostate glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA014717, HPA024110"	Enhanced		Supported	Nucleoplasm,Endosomes,Lysosomes		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 16: Non-specific - RNA binding"	"Endosomes, Lysosomes"	Nucleoplasm	"HPA014717: AB_1844373, HPA024110: AB_2204898"	"prognostic unfavorable (9.52e-4)"	"unprognostic (5.38e-3)"	"unprognostic (9.16e-2)"	"unprognostic (4.39e-2)"	"unprognostic (2.60e-2)"	"unprognostic (1.55e-2)"	"unprognostic (2.91e-3)"	"unprognostic (8.43e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.10e-1)"	"unprognostic (3.27e-2)"	"unprognostic (5.06e-2)"	"prognostic favorable (2.33e-14)"	"unprognostic (2.09e-2)"	"unprognostic (1.37e-1)"	"unprognostic (2.76e-2)"	"unprognostic (9.30e-2)"
VPS26A	"Hbeta58, PEP8A, VPS26"	ENSG00000122958	"VPS26, retromer complex component A"	O75436	10	69123512-69174412	"Plasma proteins, Predicted intracellular proteins, Transporters"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Syncytiotrophoblasts: 259.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011602, HPA057498, CAB075733"	Supported		Enhanced	Endosomes,Lysosomes		NA	NA		41000	"Cluster 7: Monocytes - Unknown function"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 67: Non-specific - Mitochondria & RNA binding"	"Cluster 67: Syncytiotrophoblasts - Pregnancy"	"Endosomes, Lysosomes"		"CAB011602: AB_2215043, CAB075733: AB_2665739, HPA057498: AB_2683448"	"unprognostic (1.17e-2)"	"unprognostic (6.94e-2)"	"unprognostic (5.58e-2)"	"unprognostic (9.35e-2)"	"unprognostic (5.95e-2)"	"prognostic unfavorable (1.72e-4)"	"prognostic unfavorable (1.70e-6)"	"unprognostic (1.17e-1)"	"unprognostic (1.35e-1)"	"unprognostic (7.88e-2)"	"prognostic unfavorable (9.18e-6)"	"unprognostic (4.63e-2)"	"unprognostic (2.15e-2)"	"unprognostic (7.14e-2)"	"unprognostic (6.68e-2)"	"unprognostic (4.33e-2)"	"unprognostic (1.72e-1)"
VPS35	"FLJ10752, MEM3, PARK17"	ENSG00000069329	"VPS35 retromer complex component"	Q96QK1	16	46656132-46689518	"Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Host-virus interaction, Protein transport, Transport"		"Neurodegeneration, Parkinson disease, Parkinsonism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA040802	Supported		Supported	Endosomes,Lysosomes		NA	NA		500000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 17: Granulosa cells - Transcription regulation"	"Endosomes, Lysosomes"		"HPA040802: AB_2677142"	"unprognostic (1.11e-2)"	"unprognostic (8.70e-2)"	"prognostic favorable (7.74e-4)"	"unprognostic (4.75e-2)"	"unprognostic (1.90e-1)"	"unprognostic (5.67e-3)"	"prognostic unfavorable (2.10e-6)"	"unprognostic (5.32e-2)"	"unprognostic (1.49e-1)"	"unprognostic (2.29e-2)"	"unprognostic (3.33e-3)"	"unprognostic (2.49e-1)"	"prognostic favorable (9.75e-5)"	"unprognostic (3.68e-3)"	"unprognostic (2.43e-1)"	"unprognostic (1.34e-1)"	"unprognostic (6.89e-3)"
VPS36	"C13orf9, CGI-145, Eap45"	ENSG00000136100	"Vacuolar protein sorting 36 homolog"	Q86VN1	13	52412602-52450634	"Predicted intracellular proteins"	"Protein transport, Transcription, Transcription regulation, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Rod photoreceptor cells: 270.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039734, HPA043947"	Approved		Supported	"Vesicles,Lysosomes,Plasma membrane,Cell Junctions"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 31: Skin - Epidermis development"	"Cluster 13: Non-specific - Nuclear processes"	"Cluster 44: Photoreceptor cells - Visual perception"	"Vesicles, Lysosomes"	"Plasma membrane, Cell Junctions"	"HPA039734: AB_2676652, HPA043947: AB_2678744"	"unprognostic (2.43e-1)"	"unprognostic (1.44e-1)"	"unprognostic (2.80e-1)"	"unprognostic (2.94e-1)"	"unprognostic (1.56e-1)"	"unprognostic (2.32e-1)"	"unprognostic (6.57e-2)"	"unprognostic (7.84e-2)"	"unprognostic (3.96e-3)"	"unprognostic (1.19e-2)"	"unprognostic (9.37e-2)"	"unprognostic (5.57e-2)"	"prognostic favorable (9.91e-6)"	"unprognostic (6.47e-3)"	"unprognostic (1.83e-1)"	"unprognostic (1.94e-1)"	"unprognostic (9.83e-2)"