Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" AARS2 "AARSL, bA444E17.1, KIAA1270" ENSG00000124608 "Alanyl-tRNA synthetase 2, mitochondrial" Q5JTZ9 6 44298731-44313347 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration, Premature ovarian failure, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035636, HPA061396" Approved Enhanced Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 64: Non-specific - Transcription" Mitochondria "HPA035636: AB_10670837, HPA061396: AB_2684502" "unprognostic (1.56e-1)" "unprognostic (3.24e-2)" "unprognostic (2.58e-2)" "unprognostic (2.04e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.83e-3)" "unprognostic (5.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-2)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" ACAD9 "MGC14452, NPD002" ENSG00000177646 "Acyl-CoA dehydrogenase family member 9" Q9H845 3 128879596-128924003 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037716, HPA046720" Supported Enhanced Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 43: Non-specific - Mitochondria" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA037716: AB_10673638, HPA046720: AB_2679773" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.61e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.67e-6)" "unprognostic (1.30e-1)" "unprognostic (3.74e-1)" "unprognostic (3.25e-2)" "unprognostic (1.37e-1)" "unprognostic (6.96e-3)" "prognostic favorable (4.32e-8)" "unprognostic (1.52e-1)" "unprognostic (2.64e-2)" "unprognostic (6.56e-2)" "unprognostic (9.96e-2)" ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.3;skeletal muscle: 380.0;tongue: 475.9" "Group enriched" "Detected in all" 4 "Cardiomyocytes: 640.9;Distal tubular cells: 236.3;Hepatocytes: 282.5;Proximal tubular cells: 529.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria NA NA 930000 "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favorable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 622.7;liver: 969.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 825.5;Distal tubular cells: 562.9;Hepatocytes: 785.7;Proximal tubular cells: 1461.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 1400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605941-95656711 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 120.1" "Cell type enhanced" "Detected in many" "Granulosa cells: 81.2;Proximal enterocytes: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Enhanced Mitochondria NA NA 48000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 21: Serous glandular cells - Salivary secretion" Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favorable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" ALDH1L2 "FLJ38508, mtFDH" ENSG00000136010 "Aldehyde dehydrogenase 1 family member L2" Q3SY69 12 105019784-105107643 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 40.7;salivary gland: 13.0" "Cell type enhanced" "Detected in many" "Early spermatids: 40.2;Excitatory neurons: 22.7;Inhibitory neurons: 23.5;Oligodendrocyte precursor cells: 24.1;Plasma cells: 23.4;Serous glandular cells: 33.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039481, HPA059282" Approved Enhanced Mitochondria No No "Cluster 25: Pancreas - Digestion" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 21: Serous glandular cells - Salivary secretion" Mitochondria "HPA039481: AB_10795465, HPA059282: AB_2732633" "unprognostic (5.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.76e-1)" "unprognostic (8.86e-2)" "unprognostic (1.75e-1)" "unprognostic (2.92e-1)" "unprognostic (5.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-8)" "unprognostic (3.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.53e-3)" "unprognostic (2.52e-5)" ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 379.1;liver: 367.1" "Group enriched" "Detected in many" 5 "Hepatocytes: 547.0;Proximal tubular cells: 784.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" APOOL "AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193" ENSG00000155008 "Apolipoprotein O like" Q6UXV4 X 85003877-85093316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000612, HPA076210" Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 48: Non-specific - RNA binding" "Cluster 15: Smooth muscle cells - Muscle contraction" Mitochondria "HPA000612: AB_1078594, HPA076210: " "prognostic unfavorable (2.68e-5)" "unprognostic (2.72e-2)" "unprognostic (6.16e-2)" "unprognostic (5.71e-3)" "unprognostic (4.27e-3)" "unprognostic (1.47e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (8.35e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.35e-12)" "unprognostic (2.67e-2)" "unprognostic (5.65e-2)" "unprognostic (7.11e-2)" "unprognostic (7.51e-2)" ARMC10 "MGC3195, SVH" ENSG00000170632 "Armadillo repeat containing 10" Q8N2F6 7 103074881-103099759 "Predicted intracellular proteins, Predicted membrane proteins" "Growth regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011036, HPA011057" Enhanced Enhanced Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 31: Non-specific - Transcription" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA011036: AB_1080139, HPA011057: AB_1080137" "unprognostic (7.03e-3)" "unprognostic (2.44e-1)" "unprognostic (8.18e-2)" "unprognostic (3.53e-1)" "prognostic unfavorable (8.90e-6)" "unprognostic (3.85e-3)" "prognostic unfavorable (3.58e-4)" "unprognostic (5.57e-2)" "unprognostic (3.49e-2)" "unprognostic (7.90e-2)" "prognostic unfavorable (2.49e-6)" "unprognostic (1.02e-1)" "unprognostic (5.78e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (1.14e-2)" "unprognostic (5.67e-2)" ATAD3A FLJ10709 ENSG00000197785 "ATPase family AAA domain containing 3A" Q9NVI7 1 1512162-1534685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058968, HPA064867, HPA065305" Approved Enhanced Mitochondria NA NA 27000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 38: Non-specific - mRNA processing" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA058968: AB_2683864, HPA064867: AB_2685375, HPA065305: AB_2685459" "unprognostic (8.42e-2)" "unprognostic (1.67e-1)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.50e-1)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.90e-5)" "unprognostic (6.62e-2)" "unprognostic (9.53e-2)" "unprognostic (5.81e-2)" "unprognostic (4.09e-2)" "unprognostic (7.66e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (3.09e-1)" "unprognostic (6.25e-2)" "unprognostic (1.87e-3)" ATAD3B "KIAA1273, TOB3" ENSG00000160072 "ATPase family AAA domain containing 3B" Q5T9A4 1 1471765-1497848 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "HPA058968, HPA064867, HPA065305" Approved Enhanced Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 38: Non-specific - mRNA processing" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA058968: AB_2683864, HPA064867: AB_2685375, HPA065305: AB_2685459" "unprognostic (6.05e-2)" "unprognostic (1.95e-1)" "unprognostic (6.54e-2)" "unprognostic (1.30e-1)" "unprognostic (1.97e-2)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.81e-5)" "unprognostic (1.51e-1)" "unprognostic (2.27e-2)" "unprognostic (2.17e-2)" "unprognostic (8.24e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (5.48e-9)" "unprognostic (2.38e-2)" "unprognostic (2.80e-1)" "unprognostic (3.00e-2)" "unprognostic (1.68e-1)" ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56645984 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2590.4;tongue: 3205.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2310.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 19000000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Mixed function" Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavorable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favorable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" ATP5IF1 "ATPI, ATPIF1, ATPIP, IP, MGC1167, MGC8898" ENSG00000130770 "ATP synthase inhibitory factor subunit 1" Q9UII2 1 28236109-28246906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4212.1;Early spermatids: 1904.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027999 Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA027999: AB_10600984" "unprognostic (2.80e-2)" "unprognostic (3.72e-2)" "unprognostic (2.95e-1)" "prognostic favorable (6.38e-8)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (6.57e-2)" "unprognostic (2.93e-2)" "unprognostic (1.40e-2)" "prognostic favorable (8.20e-4)" "unprognostic (5.94e-2)" "unprognostic (3.52e-1)" "unprognostic (6.15e-3)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (2.79e-1)" "unprognostic (1.48e-3)" BAD "BBC2, BCL2L8" ENSG00000002330 "BCL2 associated agonist of cell death" Q92934 11 64269830-64284704 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004205, HPA028185, HPA062105" Approved Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 50: Enterocytes - Absorption" Mitochondria "CAB004205: AB_626717, HPA028185: AB_10603445, HPA062105: AB_2684684" "unprognostic (1.47e-1)" "unprognostic (3.08e-2)" "unprognostic (1.17e-1)" "unprognostic (8.24e-3)" "unprognostic (2.60e-1)" "unprognostic (6.73e-2)" "unprognostic (1.24e-3)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (8.26e-2)" "unprognostic (9.04e-2)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (7.95e-2)" BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 263.2;Schwann cells: 121.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.5" "Cancer enhanced" "Detected in many" "lymphoma: 41.9;Myeloma: 64.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "CAB000003, CAB080071, CAB080083" Enhanced Enhanced Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 44: Myeloma - Humoral immune response" "Cluster 1: T-cells - Immune response" Mitochondria "CAB000003: AB_2064429, CAB080071: , CAB080083: " "unprognostic (1.11e-3)" "prognostic favorable (5.13e-5)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.93e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (8.51e-2)" "prognostic favorable (1.29e-8)" "unprognostic (6.67e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (2.63e-1)" BCL2L13 "BCL-RAMBO, MIL1" ENSG00000099968 "BCL2 like 13" Q9BXK5 22 17628855-17730855 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002052, HPA030994, HPA050377" Uncertain Enhanced Mitochondria NA NA 100000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: Non-specific - Unknown function" "Cluster 35: Bipolar cells - Visual perception" Mitochondria "CAB002052: AB_563431, HPA030994: AB_10795024, HPA050377: AB_2681107" "unprognostic (1.59e-1)" "unprognostic (8.17e-2)" "unprognostic (2.18e-3)" "unprognostic (1.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.69e-2)" "unprognostic (3.38e-1)" "unprognostic (4.97e-2)" "unprognostic (5.04e-2)" "unprognostic (9.46e-2)" "unprognostic (1.45e-2)" "unprognostic (8.21e-2)" "prognostic favorable (1.96e-8)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (4.27e-1)" "unprognostic (2.81e-1)" BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 68: Kidney - Mixed function" "Cluster 75: Myeloid cells - Innate immune response" Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: AB_1845406" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.06e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.92e-5)" "unprognostic (8.72e-3)" "unprognostic (5.16e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (7.59e-3)" CCDC90B "MDS011, MDS025" ENSG00000137500 "Coiled-coil domain containing 90B" Q9GZT6 11 83259097-83286407 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 388.3;Late spermatids: 296.4;Spermatocytes: 317.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011130, HPA011931" Supported Enhanced Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 36: Spermatids - Spermatogenesis" Mitochondria "HPA011130: AB_1846170, HPA011931: AB_2072332" "unprognostic (5.85e-2)" "unprognostic (1.33e-1)" "unprognostic (7.34e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-1)" "unprognostic (7.48e-2)" "unprognostic (2.99e-1)" "unprognostic (3.57e-3)" "unprognostic (5.76e-3)" "unprognostic (3.53e-2)" "unprognostic (6.01e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-2)" "unprognostic (2.31e-1)" "unprognostic (3.03e-1)" "unprognostic (1.62e-1)" "unprognostic (2.41e-1)" CCM2 "C7orf22, MGC4607, OSM" ENSG00000136280 "CCM2 scaffold protein" Q9BSQ5 7 44999475-45076469 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020273, HPA021669, HPA065815" Supported Enhanced Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 63: Non-specific - Unknown function" "Cluster 7: NK-cells - Immune response regulation" Mitochondria "HPA020273: AB_1846185, HPA021669: AB_1846186, HPA065815: AB_2685562" "unprognostic (4.30e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.37e-3)" "unprognostic (3.92e-1)" "unprognostic (2.65e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.03e-1)" "prognostic unfavorable (5.06e-7)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (2.81e-2)" "unprognostic (2.48e-1)" CCR7 "BLR2, CD197, CDw197, CMKBR7, EBI1" ENSG00000126353 "C-C motif chemokine receptor 7" P32248 17 40553769-40565472 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;lymphoid tissue: 84.0" "Cell type enhanced" "Detected in some" "B-cells: 170.1;Cytotrophoblasts: 152.2;Langerhans cells: 555.3;Syncytiotrophoblasts: 521.6;T-cells: 92.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 4597.2" "Lineage enriched" "Detected in all" 4 "T-cells: 4597.2" "Cancer enriched" "Detected in some" 8 "lymphoma: 127.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003796, HPA031383, HPA074467" Enhanced Enhanced Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 23: Langerhans cells - Immune response" Mitochondria "CAB003796: AB_562261, HPA031383: AB_2673854, HPA074467: AB_2686693" "prognostic favorable (3.84e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.26e-3)" "unprognostic (1.32e-3)" "unprognostic (2.35e-3)" "prognostic favorable (7.61e-7)" "unprognostic (2.71e-4)" "unprognostic (2.58e-2)" "unprognostic (4.48e-2)" "unprognostic (4.68e-4)" "unprognostic (1.10e-2)" "unprognostic (3.11e-1)" "unprognostic (1.08e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.02e-1)" "unprognostic (7.95e-2)" COA3 "CCDC56, COX25, HSPC009, MITRAC12" ENSG00000183978 "Cytochrome c oxidase assembly factor 3" Q9Y2R0 17 42795147-42798704 "Disease related genes, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 569.1;Proximal tubular cells: 685.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA031966, HPA071122" Approved Enhanced Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA031966: AB_10602115, HPA071122: " "unprognostic (1.20e-1)" "prognostic favorable (3.40e-4)" "unprognostic (5.65e-2)" "prognostic favorable (8.93e-4)" "unprognostic (7.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.78e-2)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.25e-2)" "unprognostic (8.44e-3)" "unprognostic (1.52e-1)" "prognostic favorable (6.62e-4)" "unprognostic (1.64e-1)" "unprognostic (2.70e-1)" "unprognostic (3.16e-2)" "unprognostic (3.01e-2)" COQ8B "ADCK4, COQ8, FLJ12229" ENSG00000123815 "Coenzyme Q8B" Q96D53 19 40691514-40725784 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027229, HPA027277, HPA027279, HPA028303" Supported Enhanced Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 56: Ciliated cells - Cilium assembly" Mitochondria "HPA027229: AB_10600100, HPA027277: AB_10599857, HPA027279: AB_10601219, HPA028303: AB_2672551" "unprognostic (7.57e-2)" "unprognostic (9.48e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-2)" "unprognostic (2.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.85e-1)" "unprognostic (2.27e-1)" "unprognostic (2.82e-2)" "unprognostic (1.48e-1)" "unprognostic (2.93e-2)" "unprognostic (6.18e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (2.65e-2)" COX20 "FAM36A, FLJ43269" ENSG00000203667 "Cytochrome c oxidase assembly factor COX20" Q5RI15 1 244835616-244845057 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 491.8;Distal tubular cells: 497.6;Proximal tubular cells: 522.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043617, HPA045490" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA043617: AB_10965694, HPA045490: AB_10962869" "unprognostic (5.84e-3)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (2.86e-1)" "unprognostic (3.62e-1)" "unprognostic (3.70e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.99e-1)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (2.54e-2)" "unprognostic (3.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.02e-3)" COX5B ENSG00000135940 "Cytochrome c oxidase subunit 5B" P10606 2 97646062-97648383 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1151.3;skeletal muscle: 1332.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 6641.6;Distal enterocytes: 2987.8;Distal tubular cells: 3445.6;Proximal enterocytes: 2866.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034517 Supported Enhanced Mitochondria NA NA 230000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA034517: AB_10603561" "unprognostic (4.61e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-2)" "unprognostic (2.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.73e-4)" COX6C ENSG00000164919 "Cytochrome c oxidase subunit 6C" P09669 8 99873200-99893707 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2810.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA014295, CAB016244" Enhanced Enhanced Mitochondria NA NA 210000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "CAB016244: AB_2085703, HPA014295: AB_2668966" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (6.90e-2)" "unprognostic (3.37e-2)" "unprognostic (1.58e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-2)" "unprognostic (1.29e-1)" "unprognostic (3.51e-1)" "unprognostic (3.70e-1)" "unprognostic (8.86e-2)" "unprognostic (3.47e-3)" "unprognostic (1.10e-1)" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" COX7A2L "COX7AR, COX7RP, EB1, SIG81" ENSG00000115944 "Cytochrome c oxidase subunit 7A2 like" O14548 2 42333546-42425088 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059124, CAB073545" Enhanced Nucleoli,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 16: Non-specific - RNA binding" Mitochondria Nucleoli "CAB073545: , HPA059124: AB_2683912" "unprognostic (3.90e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (5.45e-2)" "unprognostic (4.60e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.13e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-1)" "unprognostic (1.66e-2)" "unprognostic (2.43e-1)" "unprognostic (7.07e-3)" "unprognostic (1.54e-2)" "unprognostic (2.76e-1)" "unprognostic (5.53e-2)" "unprognostic (6.19e-2)" "unprognostic (1.02e-1)" CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300391 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 550.1;tongue: 600.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria NA NA 670000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "CAB075750: AB_2665756, CAB075751: AB_2665757, CAB075752: AB_2665758, CAB075753: AB_2665759, CAB075754: AB_2665760, HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" CYCS "CYC, HCS" ENSG00000172115 "Cytochrome c, somatic" P99999 7 25118656-25125260 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Electron transport, Respiratory chain, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 799.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1328.3;Distal tubular cells: 1278.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "CAB004222, CAB005126, CAB018597" Enhanced Supported Mitochondria NA NA 170000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 63: Non-specific - Unknown function" "Cluster 72: Smooth muscle cells - ECM organization" Mitochondria "CAB004222: AB_627385, CAB005126: AB_2090472, CAB018597: AB_627383" "unprognostic (3.06e-2)" "unprognostic (3.39e-1)" "unprognostic (3.32e-2)" "unprognostic (4.11e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.81e-4)" "unprognostic (4.44e-2)" "unprognostic (7.04e-3)" "unprognostic (5.67e-2)" "unprognostic (6.22e-2)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.30e-5)" "unprognostic (1.18e-1)" "unprognostic (4.94e-2)" "unprognostic (8.75e-3)" "unprognostic (7.04e-2)" DAP3 "bMRP-10, DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29" ENSG00000132676 "Death associated protein 3" P51398 1 155687960-155739010 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" Apoptosis "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023687 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: Non-specific - RNA binding" "Cluster 39: Non-specific - Translation" "Nucleoplasm, Mitochondria" "HPA023687: AB_1847472" "unprognostic (2.60e-1)" "unprognostic (2.13e-2)" "unprognostic (2.35e-1)" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.80e-1)" "unprognostic (5.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.87e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (4.14e-6)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" DHODH ENSG00000102967 "Dihydroorotate dehydrogenase (quinone)" Q02127 16 72008588-72027664 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Pyrimidine biosynthesis" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 105.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 134.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010123, HPA011942" Approved Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 36: Non-specific - Unknown function" "Cluster 29: Hepatocytes - Metabolism" Mitochondria "Nucleoplasm, Cytosol" "HPA010123: AB_1847648, HPA011942: AB_1847649" "unprognostic (4.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-2)" "unprognostic (1.41e-3)" "unprognostic (2.10e-1)" "unprognostic (4.27e-2)" "unprognostic (1.31e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-1)" "unprognostic (2.14e-1)" "unprognostic (6.40e-2)" "unprognostic (9.26e-3)" "unprognostic (1.98e-1)" "unprognostic (1.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" DIABLO "DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC" ENSG00000184047 "Diablo IAP-binding mitochondrial protein" Q9NR28 12 122207663-122227456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 13.9;Excitatory neurons: 14.3;Gastric mucus-secreting cells: 13.7;Inhibitory neurons: 13.8;Oligodendrocytes: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001825, CAB003857, CAB016688" Supported Enhanced Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" Mitochondria "CAB003857: AB_365498, CAB016688: AB_1615783, HPA001825: AB_1857247" "unprognostic (3.67e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-1)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (2.38e-3)" "unprognostic (1.40e-3)" "unprognostic (5.06e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.68e-2)" "unprognostic (2.36e-1)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase" "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1644.1;Proximal tubular cells: 2051.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239402-2252300 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria NA NA 7300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: Non-specific - Transcription" "Cluster 70: Basal prostatic cells - Lipid metabolism" Mitochondria "HPA041746: AB_10960693, HPA043227: AB_10960273" "unprognostic (4.99e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.75e-1)" "unprognostic (2.92e-3)" "unprognostic (8.90e-2)" "unprognostic (2.85e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.98e-1)" "unprognostic (2.17e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-2)" "unprognostic (2.66e-2)" "prognostic favorable (8.99e-8)" "unprognostic (2.61e-2)" "unprognostic (3.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.08e-3)" ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115693-4135597 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 422.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 260.4;Cytotrophoblasts: 301.8;Distal tubular cells: 366.9;Proximal tubular cells: 504.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 60: Proximal tubular cells - Absorption" "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favorable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 348.1;Cytotrophoblasts: 1355.8;Fibroblasts: 293.4;Syncytiotrophoblasts: 835.0;Thymic epithelial cells: 783.2" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" EIF4E2 "4EHP, EIF4EL3, IF4e" ENSG00000135930 "Eukaryotic translation initiation factor 4E family member 2" O60573 2 232550674-232583644 "Predicted intracellular proteins" "Protein biosynthesis, RNA-mediated gene silencing, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 298.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019253, HPA077074" Enhanced Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Mixed function" Mitochondria Cytosol "HPA019253: AB_1848092, HPA077074: " "unprognostic (3.44e-2)" "unprognostic (2.70e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-2)" "unprognostic (1.63e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.42e-1)" "unprognostic (5.62e-3)" "unprognostic (1.42e-2)" "unprognostic (1.31e-1)" "unprognostic (1.21e-2)" "unprognostic (1.36e-2)" "unprognostic (7.74e-2)" "unprognostic (3.34e-3)" "unprognostic (1.88e-1)" "unprognostic (9.38e-2)" ERAL1 HERA-B ENSG00000132591 "Era like 12S mitochondrial rRNA chaperone 1" O75616 17 28855010-28861061 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021425, HPA024423" Supported Enhanced Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA021425: AB_1848228, HPA024423: AB_1848229" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "unprognostic (5.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.55e-1)" "unprognostic (8.37e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (8.20e-2)" "unprognostic (7.04e-2)" "unprognostic (2.70e-1)" "unprognostic (8.57e-3)" "unprognostic (5.76e-1)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "unprognostic (2.49e-1)" "unprognostic (2.62e-1)" "unprognostic (5.79e-2)" ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76215353-76311472 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 389.7;tongue: 493.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.3;Hepatocytes: 383.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 680000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 4: Platelets - Platelet activation" Mitochondria "HPA018990: AB_1848277, HPA018993: AB_1848275, HPA018996: AB_1848276, HPA024089: AB_1848278" "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (3.71e-3)" "unprognostic (5.99e-2)" "unprognostic (6.81e-3)" "unprognostic (3.02e-1)" "unprognostic (5.01e-2)" "unprognostic (6.01e-2)" "unprognostic (3.38e-3)" "unprognostic (1.99e-1)" "prognostic favorable (5.04e-8)" "unprognostic (2.87e-1)" "unprognostic (4.90e-2)" "unprognostic (9.22e-2)" "unprognostic (2.90e-2)" ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 493.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 1230.0;Proximal enterocytes: 725.2;Proximal tubular cells: 981.1" "Cancer enhanced" "Detected in all" "liver cancer: 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA018910: AB_1848280, HPA018921: AB_1848281, HPA018923: AB_1848282" "unprognostic (1.44e-1)" "prognostic favorable (6.45e-4)" "unprognostic (8.66e-2)" "unprognostic (3.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.94e-2)" "unprognostic (3.20e-1)" "unprognostic (6.93e-3)" "unprognostic (2.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" "prognostic favorable (6.45e-5)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (4.83e-1)" "unprognostic (1.99e-1)" ETHE1 "HSCO, YF13H12" ENSG00000105755 "ETHE1 persulfide dioxygenase" O95571 19 43506719-43527230 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 256.1" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1525.5;Paneth cells: 670.7;Proximal enterocytes: 396.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028360, HPA029028, HPA029029" Enhanced Enhanced Mitochondria No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Mitochondria "HPA028360: AB_10599297, HPA029028: AB_10602092, HPA029029: AB_10601998" "unprognostic (8.04e-2)" "unprognostic (3.33e-1)" "unprognostic (1.50e-2)" "unprognostic (2.45e-1)" "unprognostic (8.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.58e-4)" "unprognostic (7.75e-2)" "unprognostic (2.28e-1)" "unprognostic (5.47e-2)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.27e-2)" "unprognostic (1.75e-1)" "unprognostic (9.72e-3)" "unprognostic (2.73e-2)" FAHD1 "C16orf36, DKFZP566J2046" ENSG00000180185 "Fumarylacetoacetate hydrolase domain containing 1" Q6P587 16 1826941-1840207 "Enzymes, Predicted intracellular proteins" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 64.1" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 112.6;Proximal tubular cells: 175.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025530, HPA043226, HPA043534" Enhanced Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 8: Non-specific - Transcription" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria Nucleoplasm "CAB025530: , HPA043226: AB_2678370, HPA043534: AB_2678535" "unprognostic (3.71e-1)" "unprognostic (1.25e-2)" "prognostic favorable (8.27e-4)" "unprognostic (1.99e-1)" "unprognostic (6.74e-2)" "unprognostic (1.01e-3)" "unprognostic (2.89e-2)" "unprognostic (4.32e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.80e-14)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (3.31e-2)" FDX1 "ADX, FDX" ENSG00000137714 "Ferredoxin 1" P10109 11 110429948-110464884 "Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Steroidogenesis, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "adrenal gland: 313.7" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 999.6;Syncytiotrophoblasts: 1358.3;Theca cells: 519.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041630, HPA062087" Enhanced Enhanced Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 70: Basal prostatic cells - Lipid metabolism" Mitochondria "HPA041630: AB_10793970, HPA062087: AB_2630366" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (5.29e-3)" "unprognostic (4.67e-2)" "unprognostic (2.39e-1)" "unprognostic (4.32e-3)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-2)" "unprognostic (4.12e-1)" "unprognostic (3.10e-2)" "unprognostic (5.48e-2)" "prognostic favorable (3.58e-7)" "prognostic favorable (2.53e-4)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" "unprognostic (2.80e-1)" FDXR "ADR, ADXR" ENSG00000161513 "Ferredoxin reductase" P22570 17 74862497-74873031 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "adrenal gland: 343.1" "Group enriched" "Detected in many" 5 "Granulosa cells: 326.3;Theca cells: 554.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "CAB008597, CAB009818, HPA044393, HPA053673" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 17: Granulosa cells - Transcription regulation" Mitochondria "CAB008597: AB_1615557, CAB009818: AB_2102601, HPA044393: AB_2678927, HPA053673: AB_2682225" "unprognostic (2.69e-2)" "unprognostic (1.17e-3)" "unprognostic (7.51e-2)" "prognostic favorable (2.38e-4)" "unprognostic (3.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-2)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (6.30e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.03e-2)" "unprognostic (2.13e-1)" FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519755 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 209.0;Early spermatids: 247.9;Syncytiotrophoblasts: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: Non-specific - RNA binding" "Cluster 18: Non-specific - Mixed function" Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" GFER "ALR, ERV1, HERV1, HPO1, HPO2, HSS" ENSG00000127554 "Growth factor, augmenter of liver regeneration" P55789 16 1984193-1987749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Oxidoreductase" "Cataract, Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 158.8;Late spermatids: 158.4;Proximal enterocytes: 399.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041227, HPA063553" Approved Enhanced Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: Non-specific - Transcription" "Cluster 50: Enterocytes - Absorption" Cytosol Mitochondria "HPA041227: AB_10795538, HPA063553: AB_2685038" "unprognostic (5.35e-2)" "unprognostic (2.11e-2)" "unprognostic (3.08e-1)" "unprognostic (4.42e-2)" "unprognostic (3.15e-1)" "unprognostic (2.63e-1)" "unprognostic (1.27e-2)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (5.93e-2)" "prognostic favorable (4.06e-4)" "unprognostic (4.93e-2)" "unprognostic (3.64e-1)" "unprognostic (3.56e-1)" "unprognostic (1.09e-2)" GRPEL2 "DKFZp451C205, FLJ23713, Mt-GrpE#2" ENSG00000164284 "GrpE like 2, mitochondrial" Q8TAA5 5 149345430-149354583 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 44.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018173, HPA023211" Approved Enhanced Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 66: Endothelial cells - Angiogenesis" Mitochondria "HPA018173: AB_1850358, HPA023211: AB_1850360" "unprognostic (3.13e-2)" "unprognostic (1.69e-1)" "prognostic favorable (3.87e-5)" "prognostic unfavorable (2.21e-4)" "unprognostic (3.22e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.16e-8)" "unprognostic (1.34e-1)" "unprognostic (8.16e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.40e-1)" "unprognostic (1.79e-1)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" GRSF1 ENSG00000132463 "G-rich RNA sequence binding factor 1" Q12849 4 70815783-70839897 "Predicted intracellular proteins" "mRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 275.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036984, HPA036985" Enhanced Enhanced Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 45: Non-specific - Cell proliferation" "Cluster 23: Langerhans cells - Immune response" Mitochondria "HPA036984: AB_2675415, HPA036985: AB_10672785" "unprognostic (1.45e-3)" "unprognostic (1.82e-2)" "prognostic favorable (1.47e-5)" "unprognostic (8.63e-2)" "unprognostic (6.73e-2)" "unprognostic (4.15e-3)" "prognostic unfavorable (8.29e-5)" "unprognostic (1.94e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (7.68e-2)" "unprognostic (8.05e-2)" "prognostic favorable (2.72e-9)" "unprognostic (6.12e-2)" "unprognostic (1.23e-1)" "unprognostic (1.78e-1)" "unprognostic (9.65e-3)" GTPBP8 HSPC135 ENSG00000163607 "GTP binding protein 8 (putative)" Q8N3Z3 3 112990984-113015060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 84.0;Spermatocytes: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034831, HPA058631" Approved Enhanced Mitochondria No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: Non-specific - Mitochondria" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" Mitochondria "HPA034831: AB_10671506, HPA058631: AB_2683783" "unprognostic (1.98e-1)" "unprognostic (1.02e-2)" "unprognostic (4.36e-2)" "unprognostic (1.99e-3)" "unprognostic (4.39e-2)" "unprognostic (2.00e-2)" "unprognostic (7.18e-3)" "unprognostic (1.80e-2)" "unprognostic (1.06e-2)" "unprognostic (2.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.21e-2)" "prognostic favorable (3.07e-5)" "unprognostic (7.10e-2)" "unprognostic (7.21e-2)" "unprognostic (4.57e-1)" "unprognostic (2.69e-1)" HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 507.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 50: Enterocytes - Absorption" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 48: Non-specific - RNA binding" "Cluster 74: Pancreatic cells - Mixed function" Mitochondria "HPA002946: AB_1079041" "prognostic unfavorable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" HEATR1 "BAP28, FLJ10359, UTP10" ENSG00000119285 "HEAT repeat containing 1" Q9H583 1 236549005-236604516 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046917, HPA062200" Approved Enhanced "Nucleoli fibrillar center,Mitochondria" NA NA 470000 "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 18: Non-specific - RNA binding" "Cluster 16: Non-specific - RNA binding" "Nucleoli fibrillar center" Mitochondria "HPA046917: AB_2679863, HPA062200: AB_2684709" "unprognostic (2.61e-1)" "unprognostic (1.44e-3)" "unprognostic (6.26e-2)" "unprognostic (1.34e-3)" "unprognostic (7.18e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (5.82e-2)" "unprognostic (4.15e-2)" "unprognostic (3.80e-1)" "unprognostic (4.67e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (8.08e-2)" "unprognostic (3.38e-1)" "unprognostic (3.27e-2)" "unprognostic (4.00e-2)" HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 280.0;Proximal tubular cells: 352.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541, HPA067080" Enhanced Enhanced Mitochondria NA NA 74000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 45: Non-specific - Cell proliferation" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA036540: AB_10673355, HPA036541: AB_2675182, HPA067080: " "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favorable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favorable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 108.8;Hepatocytes: 89.1;Proximal tubular cells: 113.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: RS4;11 - Unknown function" "Cluster 61: Non-specific - Transcription" Mitochondria "HPA020961: AB_1850715, HPA059109: AB_2683906" "unprognostic (9.64e-3)" "unprognostic (1.53e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.71e-3)" "unprognostic (2.87e-2)" "prognostic favorable (2.97e-9)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (1.72e-1)" HKDC1 "FLJ22761, FLJ37767" ENSG00000156510 "Hexokinase domain containing 1" Q2TB90 10 69220332-69267552 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.5;retina: 46.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 32.7;Ductal cells: 33.8;Endometrial ciliated cells: 44.5;Exocrine glandular cells: 25.9;Glandular and luminal cells: 47.7;Muller glia cells: 107.3;Proximal enterocytes: 52.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 5.8;naive CD8 T-cell: 2.3;T-reg: 5.4" "Lineage enriched" "Detected in single" 23 "T-cells: 5.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 67.0;Kidney cancer: 76.2" "Colon - Colon enterocytes" "Region enhanced" "Detected in many" "cerebral cortex: 11.9" "Low region specificity" "Detected in all" "HPA064198, HPA064230" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 56: Intestine - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 68: Muller glia cells - Visual perception" Mitochondria "HPA064198: AB_2685210, HPA064230: AB_2685219" "unprognostic (1.29e-2)" "unprognostic (2.26e-2)" "unprognostic (1.86e-1)" "unprognostic (8.47e-2)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (6.31e-3)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (3.11e-1)" "unprognostic (1.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.24e-1)" "unprognostic (2.10e-3)" "unprognostic (2.19e-1)" HSDL2 "C9orf99, SDR13C1" ENSG00000119471 "Hydroxysteroid dehydrogenase like 2" Q6YN16 9 112380080-112472405 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 181.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 277.9;Granulosa cells: 179.0;Late spermatids: 179.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042890, HPA050453" Enhanced Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 55: Non-specific - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" Mitochondria "HPA042890: AB_2678216, HPA050453: AB_2681131" "unprognostic (3.17e-3)" "unprognostic (1.62e-2)" "unprognostic (1.90e-3)" "prognostic favorable (9.23e-6)" "unprognostic (3.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.17e-1)" "unprognostic (5.15e-2)" "unprognostic (7.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.82e-1)" "prognostic favorable (9.29e-7)" "unprognostic (1.44e-1)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (7.35e-2)" HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486584-197516737 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 790.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria NA NA 18000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Mixed function" Mitochondria "CAB002775: , CAB072816: , HPA001523: AB_1079028, HPA050025: AB_2680995" "unprognostic (2.79e-2)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.59e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (2.25e-4)" "unprognostic (3.51e-2)" "unprognostic (9.91e-2)" "unprognostic (8.63e-3)" "unprognostic (3.47e-2)" "unprognostic (7.83e-3)" "unprognostic (5.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (4.10e-2)" IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094132-220148041 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 35000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: Non-specific - RNA binding" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA024212: AB_1851363, HPA024594: AB_1851368, HPA024596: AB_1851370" "unprognostic (2.15e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.42e-3)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.24e-5)" "unprognostic (9.48e-2)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (8.87e-2)" "unprognostic (6.27e-3)" IDH3A ENSG00000166411 "Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha" P50213 15 78131498-78171945 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 144.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041465, HPA062971" Supported Enhanced Mitochondria No No 110000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 50: Enterocytes - Absorption" Mitochondria "HPA041465: AB_10794377, HPA062971: AB_2684913" "unprognostic (2.33e-1)" "unprognostic (1.21e-1)" "unprognostic (5.76e-3)" "unprognostic (2.26e-1)" "unprognostic (1.02e-1)" "unprognostic (4.01e-1)" "unprognostic (2.29e-1)" "unprognostic (6.47e-2)" "unprognostic (1.69e-2)" "unprognostic (2.30e-1)" "unprognostic (3.05e-1)" "unprognostic (1.42e-1)" "prognostic favorable (6.49e-8)" "unprognostic (1.40e-1)" "unprognostic (3.08e-2)" "unprognostic (4.49e-2)" "unprognostic (3.39e-2)" IDH3B RP46 ENSG00000101365 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta" O43837 20 2658395-2664219 "Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 243.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049387, HPA054180" Supported Enhanced Mitochondria NA NA 8300 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA049387: AB_2680740, HPA054180: AB_2682407" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.12e-1)" "unprognostic (2.43e-2)" "unprognostic (3.24e-2)" "unprognostic (6.83e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.76e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-2)" "unprognostic (4.75e-3)" "unprognostic (1.39e-2)" "prognostic favorable (6.78e-8)" "unprognostic (8.89e-2)" "unprognostic (4.02e-2)" "unprognostic (2.79e-1)" "unprognostic (1.16e-1)" IMMP1L "FLJ25059, IMMP1" ENSG00000148950 "Inner mitochondrial membrane peptidase subunit 1" Q96LU5 11 31432401-31509645 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038372, HPA058308" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 18: Non-specific - Mixed function" Mitochondria "HPA038372: AB_10669643, HPA058308: AB_2732620" "unprognostic (2.39e-1)" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.17e-2)" "unprognostic (9.67e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (7.97e-4)" "unprognostic (7.59e-2)" "unprognostic (4.66e-3)" "unprognostic (5.15e-3)" "prognostic favorable (6.72e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (4.66e-1)" "unprognostic (4.52e-2)" "unprognostic (1.37e-2)" "unprognostic (1.04e-3)" IMMT "HMP, Mic60, MICOS60, MINOS2, P87, P89" ENSG00000132305 "Inner membrane mitochondrial protein" Q16891 2 86143932-86195472 "Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 288.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 288.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022439, HPA036164, HPA036165" Supported Enhanced Mitochondria NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Mixed function" Mitochondria "CAB022439: , HPA036164: AB_2674979, HPA036165: AB_2674980" "unprognostic (3.83e-3)" "unprognostic (1.56e-1)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.40e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (5.66e-2)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (7.35e-2)" "unprognostic (2.21e-1)" "prognostic favorable (3.51e-6)" "unprognostic (2.06e-3)" "unprognostic (6.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312229 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 59.7;Inhibitory neurons: 60.0;Rod photoreceptor cells: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 32: Neurons - Synaptic function" Mitochondria "HPA065409: AB_2685485, HPA069708: AB_2686179" "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (4.33e-2)" "unprognostic (8.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (9.91e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (9.75e-10)" "unprognostic (1.24e-2)" "unprognostic (5.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 196.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002034, HPA002192" Supported Enhanced Nucleoplasm,Mitochondria No No 7900 "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 16: Non-specific - RNA binding" Mitochondria Nucleoplasm "HPA002034: AB_2756304, HPA002192: AB_1079695" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (2.43e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.56e-2)" "unprognostic (2.71e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" LRPPRC "GP130, LRP130, LSFC" ENSG00000138095 "Leucine rich pentatricopeptide repeat containing" P42704 2 43886224-43995989 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033786, HPA036408, HPA036409" Enhanced Enhanced Mitochondria No No 210000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" Mitochondria "CAB033786: AB_2137450, HPA036408: AB_10670438, HPA036409: AB_2675108" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-3)" "prognostic unfavorable (1.72e-5)" "unprognostic (1.68e-1)" "unprognostic (8.34e-3)" "prognostic unfavorable (2.31e-7)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.44e-3)" "unprognostic (7.68e-2)" "prognostic favorable (6.65e-6)" "unprognostic (9.07e-2)" "unprognostic (1.92e-1)" "unprognostic (1.12e-1)" "unprognostic (5.00e-2)" MALSU1 "C7orf30, mtRsfA" ENSG00000156928 "Mitochondrial assembly of ribosomal large subunit 1" Q96EH3 7 23298739-23311729 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020487, HPA052210" Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 63: Non-specific - Unknown function" "Cluster 49: Early spermatids - Spermatogenesis" Mitochondria "HPA020487: AB_1845757, HPA052210: AB_2681762" "unprognostic (3.62e-1)" "unprognostic (3.68e-1)" "unprognostic (1.43e-1)" "unprognostic (4.66e-3)" "unprognostic (5.24e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (9.79e-2)" "unprognostic (1.83e-3)" "unprognostic (3.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.68e-1)" MAVS "Cardif, IPS-1, KIAA1271, VISA" ENSG00000088888 "Mitochondrial antiviral signaling protein" Q7Z434 20 3846799-3876123 "Predicted membrane proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009187, HPA049850, HPA053524" Enhanced Enhanced Mitochondria NA NA 600000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 50: Enterocytes - Absorption" Mitochondria "CAB009187: , HPA049850: AB_2680912, HPA053524: AB_2682177" "unprognostic (1.30e-2)" "unprognostic (4.51e-2)" "unprognostic (2.17e-1)" "unprognostic (6.67e-2)" "unprognostic (1.42e-1)" "unprognostic (1.75e-1)" "unprognostic (1.18e-3)" "unprognostic (2.23e-2)" "unprognostic (2.30e-2)" "unprognostic (5.95e-2)" "prognostic favorable (3.81e-4)" "unprognostic (1.92e-1)" "prognostic favorable (4.13e-5)" "unprognostic (4.97e-2)" "unprognostic (3.03e-1)" "unprognostic (3.12e-2)" "unprognostic (7.39e-2)" MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 120.5" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 109.5" "Cancer enhanced" "Detected in all" "prostate cancer: 81.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 229.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 14: Endometrium - Transcription regulation" Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favorable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favorable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" MCL1 "BCL2L3, Mcl-1" ENSG00000143384 "MCL1 apoptosis regulator, BCL2 family member" Q07820 1 150560895-150579738 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 685.1" "Cell type enhanced" "Detected in all" "Langerhans cells: 1033.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 106.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002781, HPA008455, HPA031125, CAB068195" Enhanced Enhanced Mitochondria Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: Non-specific - RNA binding" "Cluster 1: T-cells - Immune response" Mitochondria "CAB002781: , CAB068195: AB_2665695, HPA008455: AB_1079334, HPA031125: AB_10602026" "unprognostic (3.82e-2)" "unprognostic (8.79e-2)" "unprognostic (9.15e-2)" "unprognostic (2.05e-2)" "unprognostic (1.34e-1)" "unprognostic (3.91e-2)" "unprognostic (3.16e-2)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "unprognostic (8.60e-2)" "unprognostic (1.57e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.16e-4)" "unprognostic (3.22e-2)" "unprognostic (1.94e-1)" "unprognostic (4.87e-2)" "unprognostic (4.46e-2)" MDH2 ENSG00000146701 "Malate dehydrogenase 2" P40926 7 76048051-76067508 "Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 697.1;tongue: 601.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019714, HPA019716, HPA019848, HPA026720" Enhanced Enhanced Mitochondria No No 14000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA019714: AB_1853678, HPA019716: AB_1853680, HPA019848: AB_1853683, HPA026720: AB_1853685" "unprognostic (3.20e-2)" "unprognostic (2.85e-1)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (5.55e-3)" "unprognostic (8.94e-2)" "unprognostic (6.45e-2)" "unprognostic (3.77e-2)" "unprognostic (3.60e-1)" "unprognostic (2.02e-2)" "unprognostic (1.40e-1)" "unprognostic (9.70e-2)" "prognostic favorable (1.49e-5)" "unprognostic (8.57e-2)" "unprognostic (9.64e-2)" "unprognostic (5.68e-2)" "unprognostic (2.66e-1)" MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 133.4;Oligodendrocytes: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 739.7;tongue: 559.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1280.7;Distal tubular cells: 1296.8;Proximal tubular cells: 522.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045119, HPA055790" Enhanced Enhanced Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein binding" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA045119: AB_10960421, HPA055790: AB_2682923" "unprognostic (3.30e-2)" "prognostic favorable (1.45e-4)" "unprognostic (5.24e-3)" "unprognostic (1.68e-1)" "unprognostic (3.17e-2)" "unprognostic (2.85e-2)" "unprognostic (7.61e-2)" "prognostic favorable (1.29e-4)" "unprognostic (3.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (5.64e-2)" "prognostic favorable (4.79e-11)" "unprognostic (4.13e-2)" "unprognostic (1.03e-1)" "unprognostic (7.48e-2)" "unprognostic (8.45e-2)" MRPL10 "L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8" ENSG00000159111 "Mitochondrial ribosomal protein L10" Q7Z7H8 17 47823272-47831541 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021234, HPA029885" Enhanced Enhanced Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 7: NK-cells - Immune response regulation" Mitochondria "HPA021234: AB_1854098, HPA029885: AB_2673233" "unprognostic (6.84e-3)" "unprognostic (1.03e-1)" "unprognostic (8.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.97e-1)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.67e-4)" "unprognostic (5.21e-2)" "unprognostic (1.03e-1)" "unprognostic (8.91e-2)" "unprognostic (1.38e-1)" "unprognostic (6.16e-2)" "unprognostic (1.29e-1)" "unprognostic (2.82e-1)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (6.87e-2)" MRPL45 MGC11321 ENSG00000278845 "Mitochondrial ribosomal protein L45" 17 38297023-38323217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebral cortex: 8.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023373, HPA023385" Enhanced Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein binding" "Cluster 39: Non-specific - Translation" Mitochondria "HPA023373: AB_1854114, HPA023385: AB_1854115" "unprognostic (8.56e-3)" "unprognostic (4.09e-2)" "unprognostic (1.11e-2)" "unprognostic (3.08e-1)" "unprognostic (9.50e-2)" "unprognostic (2.22e-3)" "unprognostic (1.11e-2)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "unprognostic (1.37e-2)" "unprognostic (3.65e-1)" "unprognostic (1.35e-1)" "unprognostic (6.01e-3)" "unprognostic (3.07e-1)" "unprognostic (1.00e-1)" "unprognostic (2.40e-1)" "unprognostic (8.13e-2)" MRPS36 "DC47, MRP-S36" ENSG00000134056 "Mitochondrial ribosomal protein S36" P82909 5 69217760-69230158 "Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 502.5;Distal tubular cells: 432.3;Proximal tubular cells: 541.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035802, HPA056795" Supported Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA035802: AB_10600933, HPA056795: AB_2683237" "unprognostic (1.19e-1)" "unprognostic (6.78e-3)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (2.96e-3)" "unprognostic (1.99e-1)" "unprognostic (7.49e-2)" "unprognostic (1.49e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (3.90e-1)" "prognostic favorable (5.02e-6)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (1.37e-2)" "unprognostic (4.84e-3)" MTHFD1L "DKFZP586G1517, FLJ21145, FTHFSDC1" ENSG00000120254 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like" Q6UB35 6 150865679-151101887 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.8;Extravillous trophoblasts: 186.1;Granulosa cells: 86.0;Microglial cells: 123.1;Syncytiotrophoblasts: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;T-cells: 1.8" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015006, HPA029040, HPA029041, HPA050052, HPA074911" Approved Enhanced Mitochondria NA NA 89000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 17: Granulosa cells - Transcription regulation" Mitochondria "HPA015006: AB_1854178, HPA029040: AB_2672879, HPA029041: AB_2672880, HPA050052: AB_2680998, HPA074911: AB_2686723" "unprognostic (3.66e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (3.25e-1)" "prognostic unfavorable (5.10e-4)" "prognostic unfavorable (8.33e-5)" "unprognostic (6.35e-3)" "unprognostic (2.45e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "unprognostic (2.93e-2)" "unprognostic (3.51e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (8.69e-5)" MTIF2 IF-2mt ENSG00000085760 "Mitochondrial translational initiation factor 2" P46199 2 55236595-55269347 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 129.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006021, HPA061422" Approved Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA006021: AB_2147687, HPA061422: AB_2684514" "unprognostic (2.91e-2)" "unprognostic (9.58e-2)" "unprognostic (1.52e-2)" "unprognostic (1.87e-3)" "unprognostic (8.86e-2)" "unprognostic (5.57e-2)" "unprognostic (9.76e-3)" "unprognostic (1.88e-1)" "unprognostic (6.85e-3)" "unprognostic (3.01e-2)" "unprognostic (6.58e-3)" "unprognostic (1.76e-1)" "unprognostic (3.98e-2)" "unprognostic (2.54e-2)" "unprognostic (1.66e-1)" "unprognostic (9.45e-3)" "unprognostic (1.33e-1)" MYO19 "FLJ22865, MYOHD1" ENSG00000278259 "Myosin XIX" Q96H55 17 36495636-36543435 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021415, HPA059715" Approved Enhanced Mitochondria,Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 65: Breast cancer - Unknown function" "Cluster 24: Spermatids - Unknown function" Mitochondria Cytosol "HPA021415: AB_2266815, HPA059715: AB_2684111" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (8.44e-3)" "unprognostic (1.46e-1)" "unprognostic (2.02e-1)" "unprognostic (4.89e-3)" "prognostic unfavorable (8.33e-6)" "unprognostic (1.07e-3)" "unprognostic (1.39e-2)" "unprognostic (2.41e-1)" "unprognostic (1.67e-1)" "unprognostic (3.70e-3)" "unprognostic (1.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.57e-1)" "unprognostic (1.89e-1)" "unprognostic (4.17e-2)" NDUFAF2 "B17.2L, mimitin, MMTN, NDUFA12L" ENSG00000164182 "NADH:ubiquinone oxidoreductase complex assembly factor 2" Q8N183 5 60945177-61154531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "HPA048082, HPA054776" Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 47: Non-specific - Unknown function" "Cluster 57: Non-specific - Translation" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA048082: AB_2680254, HPA054776: AB_2682598" "unprognostic (7.28e-2)" "unprognostic (6.83e-2)" "unprognostic (1.37e-1)" "unprognostic (2.46e-3)" "unprognostic (2.41e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.06e-1)" "unprognostic (4.76e-2)" "unprognostic (8.40e-3)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.79e-2)" "unprognostic (6.10e-2)" "unprognostic (2.37e-1)" "unprognostic (4.66e-2)" NDUFB6 "B17, CI" ENSG00000165264 "NADH:ubiquinone oxidoreductase subunit B6" O95139 9 32553001-32573184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 866.7;Early spermatids: 1020.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044001, HPA053334" Supported Enhanced Mitochondria No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA044001: AB_10959448, HPA053334: AB_2682116" "unprognostic (4.09e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.81e-2)" "unprognostic (1.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-3)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.47e-10)" "unprognostic (2.70e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" NDUFB8 "ASHI, CI-ASHI" ENSG00000166136 "NADH:ubiquinone oxidoreductase subunit B8" O95169 10 100523740-100530000 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 908.0;Proximal tubular cells: 902.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "HPA003886, HPA065549" Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA003886: AB_1079463, HPA065549: " "unprognostic (4.07e-2)" "unprognostic (1.95e-3)" "unprognostic (2.28e-1)" "unprognostic (7.33e-2)" "unprognostic (4.88e-2)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (6.46e-2)" "unprognostic (8.33e-2)" "unprognostic (9.09e-2)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-2)" NDUFV3 CI-10k ENSG00000160194 "NADH:ubiquinone oxidoreductase subunit V3" P56181 21 42879644-42913304 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 894.7;Late spermatids: 1657.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019791, HPA020463, HPA030427, CAB034142" Enhanced Enhanced Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 65: Breast cancer - Unknown function" "Cluster 51: Late spermatids - Spermatogenesis" Mitochondria "CAB034142: AB_2298212, HPA019791: AB_1854357, HPA020463: AB_1854358, HPA030427: AB_10603024" "unprognostic (1.62e-1)" "unprognostic (2.17e-3)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.11e-2)" "unprognostic (4.69e-1)" "unprognostic (2.97e-2)" "unprognostic (1.05e-1)" "unprognostic (3.13e-1)" "unprognostic (3.85e-3)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (6.56e-2)" "unprognostic (9.30e-3)" "unprognostic (2.14e-1)" "unprognostic (1.94e-1)" NGRN DSC92 ENSG00000182768 "Neugrin, neurite outgrowth associated" Q9NPE2 15 90265659-90275778 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 385.3;skeletal muscle: 376.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 65.4;Excitatory neurons: 57.5;Inhibitory neurons: 52.6;Squamous epithelial cells: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA041367, HPA076267" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitochondria" "Intracellular and membrane" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" Mitochondria "Nucleoplasm, Cytokinetic bridge" "HPA041367: AB_10796668, HPA076267: " "unprognostic (2.82e-1)" "unprognostic (1.04e-2)" "unprognostic (1.66e-3)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.19e-2)" "unprognostic (2.94e-2)" "unprognostic (5.00e-2)" "unprognostic (7.78e-2)" "unprognostic (1.93e-2)" "unprognostic (5.22e-2)" "unprognostic (7.22e-2)" "unprognostic (3.31e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.68e-3)" "unprognostic (3.21e-1)" OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 155.4" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 925.4;Pancreatic endocrine cells: 647.5;Proximal enterocytes: 719.1;Proximal tubular cells: 1238.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" Mitochondria "HPA040979: AB_10795497, HPA041090: AB_10796236" "unprognostic (4.29e-1)" "unprognostic (2.69e-1)" "unprognostic (3.76e-2)" "prognostic favorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (9.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-1)" "prognostic favorable (6.56e-4)" "prognostic unfavorable (6.89e-4)" "unprognostic (1.38e-1)" "prognostic favorable (2.67e-5)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (8.24e-3)" "prognostic favorable (2.34e-4)" OGDH "E1k, KGD1, OGDC-E1, OGDH2" ENSG00000105953 "Oxoglutarate dehydrogenase" Q02218 7 44606572-44709066 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 324.0;skeletal muscle: 363.6;tongue: 374.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019514, HPA020347" Supported Enhanced Mitochondria No No 130000 "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 63: Non-specific - Unknown function" "Cluster 75: Myeloid cells - Innate immune response" Mitochondria "HPA019514: AB_1854772, HPA020347: AB_1854773" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (4.39e-1)" "unprognostic (5.64e-3)" "unprognostic (3.02e-3)" "unprognostic (1.20e-1)" "unprognostic (3.45e-1)" "unprognostic (7.58e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.30e-2)" "prognostic favorable (2.22e-14)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (2.23e-2)" "unprognostic (5.88e-3)" OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 245.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 309.6;Distal tubular cells: 227.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "cervical cancer: 178.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA 440000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Enzymes" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 57.9;Hepatocytes: 164.5;Late spermatids: 57.3" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Enzymes" "Cluster 70: Basal prostatic cells - Lipid metabolism" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 196.1;kidney: 99.1;liver: 374.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 311.4;Proximal enterocytes: 777.5;Proximal tubular cells: 139.9" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria NA NA 3500000 "Cluster 51: Monocytes - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 59: Proximal enterocytes - Transmembrane transport" Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favorable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" PHB2 "Bap37, BCAP37, p22, REA" ENSG00000215021 "Prohibitin 2" Q99623 12 6965327-6970780 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014889, CAB026335, HPA039874" Supported Enhanced Mitochondria NA NA 77000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 39: Non-specific - Translation" Mitochondria "CAB014889: , CAB026335: AB_2283865, HPA039874: AB_2616448" "unprognostic (4.64e-3)" "unprognostic (4.32e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.80e-4)" "unprognostic (3.07e-3)" "unprognostic (1.67e-1)" "unprognostic (2.53e-1)" "unprognostic (1.62e-1)" "unprognostic (1.98e-1)" "unprognostic (7.18e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (1.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.07e-1)" "unprognostic (8.17e-2)" "unprognostic (5.61e-2)" PMPCA "Alpha-MPP, CLA1, INPP5E, KIAA0123, SCAR2" ENSG00000165688 "Peptidase, mitochondrial processing subunit alpha" Q10713 9 136410641-136423761 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021648, HPA063735" Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 55: Non-specific - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria "HPA021648: AB_1855491, HPA063735: AB_2685108" "unprognostic (9.80e-2)" "unprognostic (1.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.69e-2)" "unprognostic (4.01e-2)" "unprognostic (8.19e-2)" "unprognostic (6.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.97e-1)" "unprognostic (3.32e-2)" "prognostic favorable (8.00e-5)" "unprognostic (9.47e-3)" "prognostic favorable (2.14e-6)" "unprognostic (4.27e-3)" "unprognostic (1.57e-2)" "unprognostic (2.40e-1)" "unprognostic (3.54e-2)" PMPCB "MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing subunit beta" O75439 7 103297435-103329511 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria No No 19000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 31: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" Mitochondria "HPA040674: AB_10961998, HPA074168: AB_2686671" "prognostic favorable (2.79e-4)" "unprognostic (3.11e-1)" "unprognostic (7.18e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "unprognostic (7.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-3)" "prognostic favorable (2.95e-8)" "unprognostic (2.59e-2)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" PNKD "BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, MR-1S, PDC, PKND1, TAHCCP2" ENSG00000127838 "PNKD metallo-beta-lactamase domain containing" Q8N490 2 218270392-218346793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 463.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010134, HPA017068" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA010134: AB_1079645, HPA017068: AB_1855495" "unprognostic (3.15e-3)" "unprognostic (1.80e-2)" "unprognostic (5.86e-3)" "unprognostic (1.89e-2)" "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (3.81e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (7.51e-2)" "unprognostic (3.29e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (5.13e-5)" "unprognostic (7.98e-2)" "unprognostic (2.17e-1)" "unprognostic (9.61e-2)" "unprognostic (1.44e-3)" PTCD3 "DKFZp666K071, FLJ20758" ENSG00000132300 "Pentatricopeptide repeat domain 3" Q96EY7 2 86106223-86142157 "Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 145.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041154, HPA041382" Supported Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA041154: AB_10795488, HPA041382: AB_10795695" "unprognostic (1.16e-2)" "unprognostic (4.47e-2)" "unprognostic (1.37e-2)" "unprognostic (9.30e-3)" "unprognostic (2.40e-2)" "unprognostic (2.54e-1)" "unprognostic (4.92e-3)" "unprognostic (2.06e-2)" "unprognostic (4.78e-2)" "unprognostic (3.78e-1)" "unprognostic (7.42e-3)" "unprognostic (5.49e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.77e-4)" "unprognostic (3.69e-1)" "unprognostic (7.79e-2)" "prognostic favorable (6.86e-4)" PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 197.5;Late spermatids: 579.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043932, HPA060060" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 6: Late spermatids - Spermatogenesis" Mitochondria "HPA043932: AB_2678738, HPA060060: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" RMDN3 "FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3" ENSG00000137824 "Regulator of microtubule dynamics 3" Q96TC7 15 40735884-40755851 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 97.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009975, HPA074840" Supported Enhanced "Cytokinetic bridge,Mitochondria" Yes No 42000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 45: Non-specific - Cell proliferation" "Cluster 19: Macrophages - Innate immune response" Mitochondria "Cytokinetic bridge" "HPA009975: AB_1078811, HPA074840: " "unprognostic (2.54e-2)" "unprognostic (3.53e-1)" "unprognostic (2.35e-2)" "unprognostic (3.97e-3)" "unprognostic (1.50e-1)" "unprognostic (2.50e-3)" "unprognostic (2.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.94e-3)" "prognostic favorable (6.70e-8)" "unprognostic (1.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.79e-3)" "unprognostic (2.04e-3)" SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218241-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 601.0;skeletal muscle: 479.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 459.4;Proximal enterocytes: 261.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "CAB034929, HPA041981, HPA064582" Enhanced Supported Nucleoli,Mitochondria No No 360000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Enzymes" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293" "prognostic unfavorable (6.00e-4)" "unprognostic (1.93e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "prognostic favorable (9.53e-8)" "unprognostic (1.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (1.79e-1)" SFXN1 "FLJ12876, SLC56A1" ENSG00000164466 "Sideroflexin 1" Q9H9B4 5 175477062-175529742 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.8" "Group enriched" "Detected in all" 5 "granulocytes: 99.8;T-cells: 36.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019543, HPA063745" Approved Enhanced Mitochondria NA NA 23000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 57: Non-specific - Translation" "Cluster 1: T-cells - Immune response" Mitochondria "HPA019543: AB_1856789, HPA063745: AB_2685111" "unprognostic (4.77e-3)" "unprognostic (5.26e-2)" "unprognostic (1.54e-2)" "unprognostic (3.62e-3)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (3.59e-2)" "unprognostic (8.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.17e-2)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.31e-1)" "unprognostic (7.30e-2)" "unprognostic (4.98e-1)" "unprognostic (1.08e-3)" "unprognostic (4.23e-2)" SFXN3 "SFX3, SLC56A3" ENSG00000107819 "Sideroflexin 3" Q9BWM7 10 101031234-101041244 "Metabolic proteins, Predicted membrane proteins" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 192.3;Proximal enterocytes: 108.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008028, HPA048105" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 45: Intestine - Brush border" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 51: Late spermatids - Spermatogenesis" Mitochondria "HPA008028: AB_1079938, HPA048105: AB_2680265" "unprognostic (2.55e-1)" "unprognostic (3.32e-2)" "unprognostic (4.94e-2)" "unprognostic (2.82e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (3.79e-4)" "unprognostic (3.84e-3)" "unprognostic (8.46e-2)" "unprognostic (1.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.04e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (3.56e-1)" "unprognostic (3.05e-2)" "unprognostic (3.70e-2)" "unprognostic (1.71e-1)" SLC25A24 "APC1, DKFZp586G0123" ENSG00000085491 "Solute carrier family 25 member 24" Q6NUK1 1 108134043-108200849 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028519, HPA063636" Enhanced Enhanced Mitochondria NA NA 19000 "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: Non-specific - mRNA processing" "Cluster 26: Intestinal epithelial cells - Absorption" Mitochondria "HPA028519: AB_10603890, HPA063636: AB_2685068" "unprognostic (1.94e-2)" "unprognostic (7.30e-3)" "prognostic favorable (1.01e-4)" "unprognostic (7.11e-2)" "unprognostic (1.64e-2)" "unprognostic (2.91e-1)" "unprognostic (8.54e-4)" "unprognostic (1.51e-2)" "unprognostic (7.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-3)" "unprognostic (6.18e-2)" "unprognostic (6.76e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" SLC25A31 "ANT4, DKFZP434N1235" ENSG00000151475 "Solute carrier family 25 member 31" Q9H0C2 4 127730400-127774292 "Predicted membrane proteins, Transporters" "Antiport, Differentiation, Spermatogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 272 "testis: 47.3" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 172.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015064, HPA016841, HPA046835, HPA071684" Uncertain Enhanced Mitochondria NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 56: Neurons - Neuronal signaling" "Cluster 31: Spermatocytes - Spermatogenesis" Mitochondria "HPA015064: AB_1847691, HPA016841: AB_1847690, HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (8.15e-2)" "unprognostic (1.62e-1)" "unprognostic (2.70e-1)" "unprognostic (5.32e-1)" SOD2 GClnc1 ENSG00000112096 "Superoxide dismutase 2" P04179 6 159669069-159762529 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 1083.7;skeletal muscle: 3230.1" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 2571.2;Ductal cells: 2101.9;Exocrine glandular cells: 1939.0;Glandular and luminal cells: 2209.4;monocytes: 2712.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 4470.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 4470.5" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001814, CAB002013" Supported Enhanced Mitochondria NA NA 55000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 75: Myeloid cells - Innate immune response" Mitochondria "CAB002013: , HPA001814: AB_1080134" "unprognostic (2.47e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-1)" "unprognostic (1.57e-2)" "unprognostic (1.31e-1)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (3.10e-2)" "unprognostic (1.37e-1)" "unprognostic (6.67e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (8.12e-2)" "unprognostic (4.14e-2)" "unprognostic (5.99e-2)" "unprognostic (1.82e-1)" SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 232.2;tongue: 271.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 207.4;Early spermatids: 225.4;Late spermatids: 315.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: Non-specific - Nuclear processes" "Cluster 51: Late spermatids - Spermatogenesis" Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 102.9;Proximal enterocytes: 86.1;Proximal tubular cells: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA021626: AB_1846148, HPA021643: AB_1846149, HPA024294: AB_1846150" "unprognostic (1.26e-1)" "unprognostic (2.92e-2)" "unprognostic (4.55e-3)" "unprognostic (9.82e-2)" "unprognostic (1.30e-1)" "unprognostic (9.30e-3)" "unprognostic (2.83e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (5.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" TBRG4 "Cpr2, FASTKD4, H_TD2522F11.8, KIAA0948" ENSG00000136270 "Transforming growth factor beta regulator 4" Q969Z0 7 45100100-45112047 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020582, HPA050430" Approved Enhanced Mitochondria NA NA 23000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 63: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA020582: AB_1857804, HPA050430: AB_2681125" "unprognostic (2.22e-1)" "unprognostic (4.75e-2)" "unprognostic (1.19e-1)" "unprognostic (3.46e-3)" "unprognostic (1.41e-2)" "unprognostic (9.29e-3)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.15e-2)" "unprognostic (1.86e-1)" "unprognostic (2.83e-1)" "unprognostic (4.53e-1)" "unprognostic (1.25e-2)" "unprognostic (3.66e-3)" "unprognostic (3.91e-2)" "unprognostic (3.84e-2)" "unprognostic (3.30e-1)" "unprognostic (1.52e-1)" TEFM "C17orf42, FLJ22729" ENSG00000172171 "Transcription elongation factor, mitochondrial" Q96QE5 17 30897336-30906238 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023788, HPA053044" Approved Enhanced Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA023788: AB_1848818, HPA053044: AB_2682023" "unprognostic (1.22e-1)" "unprognostic (1.18e-2)" "unprognostic (1.11e-3)" "unprognostic (3.31e-2)" "unprognostic (7.89e-2)" "unprognostic (3.75e-1)" "prognostic unfavorable (9.20e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (2.11e-1)" "unprognostic (6.18e-3)" "unprognostic (9.39e-2)" "unprognostic (4.79e-2)" "unprognostic (7.90e-2)" "unprognostic (1.92e-1)" "unprognostic (2.23e-1)" "unprognostic (8.37e-3)" TFAM "TCF6, TCF6L2" ENSG00000108064 "Transcription factor A, mitochondrial" Q00059 10 58385345-58399220 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 320.4;Late spermatids: 1067.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040648, HPA063684" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 36: Spermatids - Spermatogenesis" Mitochondria "HPA040648: AB_10795635, HPA063684: AB_2685089" "unprognostic (5.30e-2)" "unprognostic (1.14e-1)" "unprognostic (6.34e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.10e-2)" "unprognostic (3.40e-2)" "unprognostic (1.54e-2)" "unprognostic (3.23e-2)" "unprognostic (1.24e-2)" "prognostic favorable (2.74e-4)" "unprognostic (1.99e-2)" "unprognostic (5.39e-2)" "prognostic favorable (2.22e-5)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (6.76e-2)" TFB2M "FLJ22661, FLJ23182, Hkp1" ENSG00000162851 "Transcription factor B2, mitochondrial" Q9H5Q4 1 246540561-246566261 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028482, HPA028554, HPA030265" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: Non-specific - RNA binding" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA028482: AB_2672633, HPA028554: AB_2732441, HPA030265: AB_10696209" "unprognostic (4.38e-2)" "unprognostic (2.45e-2)" "unprognostic (3.79e-3)" "unprognostic (5.63e-2)" "unprognostic (1.10e-1)" "unprognostic (8.13e-2)" "unprognostic (8.76e-2)" "unprognostic (1.41e-1)" "unprognostic (2.51e-2)" "unprognostic (1.68e-2)" "unprognostic (2.46e-1)" "unprognostic (6.81e-2)" "unprognostic (5.26e-2)" "unprognostic (2.27e-1)" "unprognostic (9.44e-2)" "unprognostic (6.41e-2)" "unprognostic (3.53e-2)" TIMM10 "TIM10, TIM10A, TIMM10A" ENSG00000134809 "Translocase of inner mitochondrial membrane 10" P62072 11 57528464-57530803 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 276.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039946 Supported Enhanced Mitochondria NA NA 16000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA039946: AB_10673023" "unprognostic (9.34e-3)" "unprognostic (1.16e-2)" "unprognostic (2.21e-1)" "unprognostic (2.01e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-2)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (3.40e-3)" "unprognostic (7.62e-2)" "unprognostic (1.18e-1)" "unprognostic (5.96e-2)" "unprognostic (9.87e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-2)" "unprognostic (2.15e-2)" TIMM17A "TIM17, TIM17A" ENSG00000134375 "Translocase of inner mitochondrial membrane 17A" Q99595 1 201955503-201970664 "Cancer-related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 311.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010083 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: Non-specific - RNA binding" "Cluster 40: Plasma cells - Humoral immune response" "Nucleoplasm, Mitochondria" "HPA010083: AB_10602899" "prognostic unfavorable (1.98e-5)" "unprognostic (3.28e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.80e-3)" "unprognostic (7.58e-2)" "unprognostic (4.15e-2)" "unprognostic (7.45e-2)" "unprognostic (1.64e-2)" "unprognostic (8.54e-3)" "unprognostic (2.02e-2)" "unprognostic (2.01e-1)" "unprognostic (6.45e-3)" "unprognostic (1.21e-1)" "unprognostic (1.44e-2)" "unprognostic (2.81e-1)" TIMM44 TIM44 ENSG00000104980 "Translocase of inner mitochondrial membrane 44" O43615 19 7926718-7943667 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043052, HPA073108" Supported Enhanced Mitochondria NA NA 9100 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA043052: AB_10795713, HPA073108: " "unprognostic (1.75e-1)" "unprognostic (7.44e-3)" "unprognostic (2.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-2)" "unprognostic (5.81e-3)" "unprognostic (8.78e-2)" "unprognostic (2.42e-1)" "unprognostic (8.81e-2)" "unprognostic (2.07e-3)" "unprognostic (8.93e-2)" "unprognostic (1.80e-2)" "unprognostic (6.01e-2)" "unprognostic (6.43e-2)" "unprognostic (2.07e-2)" "unprognostic (4.18e-2)" TIMMDC1 "C3orf1, FLJ22597" ENSG00000113845 "Translocase of inner mitochondrial membrane domain containing 1" Q9NPL8 3 119498547-119525090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053214, HPA055846" Uncertain Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondria" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA053214: AB_2682081, HPA055846: AB_2682941" "unprognostic (3.95e-2)" "unprognostic (8.85e-2)" "unprognostic (1.73e-1)" "unprognostic (2.53e-2)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (9.60e-2)" "unprognostic (6.25e-2)" "unprognostic (3.39e-1)" "unprognostic (4.67e-3)" "unprognostic (1.05e-1)" "unprognostic (3.87e-2)" "unprognostic (8.89e-2)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-1)" TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;heart muscle: 37.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 19.8;Kupffer cells: 31.5;Langerhans cells: 34.5;Macrophages: 23.2;monocytes: 20.0;NK-cells: 66.7;Schwann cells: 21.6;T-cells: 34.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 9.7" "Immune cell enhanced" "Detected in all" "neutrophil: 269.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.0" "Cancer enhanced" "Detected in many" "Bone cancer: 9.7;Leukemia: 8.4" "Colon - Enteric glia cells, Kidney - T-cells, Lung - NK-cells (Lung)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Mitochondria "HPA058401: AB_2683707, HPA070655: AB_2686292" "unprognostic (1.39e-3)" "unprognostic (7.27e-2)" "unprognostic (8.82e-2)" "unprognostic (3.10e-3)" "unprognostic (7.94e-2)" "unprognostic (3.91e-3)" "unprognostic (4.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (8.83e-2)" "unprognostic (1.90e-2)" "unprognostic (6.29e-3)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" TNRC18 "CAGL79, KIAA1856, TNRC18A" ENSG00000182095 "Trinucleotide repeat containing 18" O15417 7 5306790-5425414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 20.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020730, HPA024251" Uncertain Supported "Nucleoplasm,Nuclear membrane,Mitochondria,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 63: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Nuclear membrane, Mitochondria" Cytosol "HPA020730: AB_2670506, HPA024251: AB_2671498" "unprognostic (1.66e-1)" "unprognostic (3.17e-3)" "unprognostic (2.67e-3)" "unprognostic (4.44e-1)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "unprognostic (1.13e-2)" "unprognostic (1.79e-1)" "unprognostic (3.01e-1)" "unprognostic (2.11e-2)" "unprognostic (6.08e-2)" "unprognostic (1.36e-1)" "unprognostic (9.29e-3)" "unprognostic (2.14e-1)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (4.34e-2)" TOMM20 "KIAA0016, MAS20, MOM19, TOM20" ENSG00000173726 "Translocase of outer mitochondrial membrane 20" Q15388 1 235109341-235128837 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005585, HPA011562" Supported Enhanced Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: Non-specific - RNA binding" "Cluster 39: Non-specific - Translation" Mitochondria "CAB005585: AB_628381, HPA011562: AB_1080326" "unprognostic (1.30e-1)" "unprognostic (3.08e-3)" "unprognostic (1.66e-2)" "unprognostic (4.49e-2)" "unprognostic (8.65e-3)" "unprognostic (1.17e-2)" "unprognostic (7.09e-2)" "unprognostic (3.28e-1)" "unprognostic (3.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.16e-3)" "unprognostic (5.05e-2)" "unprognostic (7.08e-3)" "unprognostic (2.33e-2)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (3.97e-1)" TOMM22 TOM22 ENSG00000100216 "Translocase of outer mitochondrial membrane 22" Q9NS69 22 38681957-38685421 "Predicted membrane proteins" "Protein transport, Translocation, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003037, HPA074642" Supported Enhanced Mitochondria NA NA 230000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 39: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA003037: AB_1080329, HPA074642: " "unprognostic (5.54e-2)" "unprognostic (5.04e-3)" "unprognostic (2.74e-3)" "unprognostic (1.48e-2)" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (1.01e-1)" "unprognostic (4.28e-1)" "unprognostic (7.01e-2)" "unprognostic (1.64e-2)" "unprognostic (7.39e-2)" "unprognostic (5.44e-2)" "unprognostic (5.32e-2)" "unprognostic (1.99e-1)" "unprognostic (7.86e-2)" "unprognostic (1.64e-1)" TOMM40 "C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40" ENSG00000130204 "Translocase of outer mitochondrial membrane 40" O96008 19 44890569-44903689 "Predicted intracellular proteins, Transporters" "Ion transport, Protein transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036231, HPA036232" Supported Enhanced Mitochondria,Cytosol NA NA 45000 "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria Cytosol "HPA036231: AB_2675010, HPA036232: AB_2675011" "unprognostic (2.14e-1)" "unprognostic (9.58e-3)" "unprognostic (1.66e-1)" "unprognostic (6.75e-3)" "unprognostic (2.37e-1)" "unprognostic (2.17e-2)" "unprognostic (1.13e-3)" "unprognostic (1.13e-2)" "unprognostic (7.84e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (5.86e-3)" "unprognostic (5.30e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.87e-1)" TOMM70 "KIAA0719, Tom70, TOMM70A" ENSG00000154174 "Translocase of outer mitochondrial membrane 70" O94826 3 100363431-100401089 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014589, CAB017156, HPA048020" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mixed function" Mitochondria "CAB017156: , HPA014589: AB_1858185, HPA048020: AB_2680234" "unprognostic (2.74e-2)" "unprognostic (2.25e-1)" "unprognostic (2.57e-2)" "unprognostic (2.69e-3)" "unprognostic (2.12e-2)" "unprognostic (5.96e-2)" "unprognostic (2.06e-3)" "unprognostic (5.01e-2)" "unprognostic (9.86e-2)" "unprognostic (1.21e-1)" "unprognostic (9.73e-3)" "unprognostic (5.38e-2)" "unprognostic (2.62e-3)" "unprognostic (1.73e-1)" "unprognostic (3.53e-1)" "unprognostic (3.34e-2)" "unprognostic (6.98e-3)" TRAP1 "HSP75, HSP90L" ENSG00000126602 "TNF receptor associated protein 1" Q12931 16 3651639-3717553 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041082, HPA044227" Enhanced Enhanced Mitochondria NA NA 1700000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: Non-specific - Transcription" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA041082: AB_2677291, HPA044227: AB_2678864" "unprognostic (1.18e-1)" "unprognostic (1.51e-1)" "prognostic favorable (1.80e-4)" "unprognostic (7.10e-2)" "unprognostic (6.80e-2)" "unprognostic (2.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.61e-2)" "unprognostic (8.58e-2)" "unprognostic (5.71e-3)" "unprognostic (1.54e-1)" "unprognostic (7.69e-3)" "unprognostic (1.01e-2)" "unprognostic (2.24e-2)" "unprognostic (6.68e-2)" "unprognostic (9.90e-2)" "unprognostic (3.82e-2)" TTC19 "FLJ20343, MGC19520" ENSG00000011295 "Tetratricopeptide repeat domain 19" Q6DKK2 17 15999784-16045015 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023010, HPA052380" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 49: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" Mitochondria "HPA023010: AB_1858429, HPA052380: AB_2681806" "unprognostic (1.04e-2)" "unprognostic (4.90e-3)" "unprognostic (2.87e-2)" "unprognostic (4.80e-3)" "unprognostic (8.09e-2)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.84e-2)" "unprognostic (8.34e-2)" "unprognostic (1.72e-2)" "unprognostic (2.30e-3)" "unprognostic (5.14e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.31e-1)" "unprognostic (3.22e-1)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846348 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria NA NA 610000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: Non-specific - Transcription" "Cluster 16: Non-specific - RNA binding" Mitochondria "CAB075730: AB_2665736, CAB075731: AB_2665737, CAB075732: AB_2665738, HPA018991: AB_1858458, HPA024087: AB_1858459" "unprognostic (1.40e-1)" "unprognostic (7.56e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.55e-2)" "unprognostic (3.39e-1)" "unprognostic (1.23e-3)" "unprognostic (8.05e-2)" "unprognostic (8.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "prognostic favorable (2.69e-6)" "unprognostic (5.26e-2)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (7.36e-2)" TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 84000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 54: Extravillous trophoblasts - Unknown function" Mitochondria "CAB008681: AB_1623682, HPA000994: AB_1080267" "unprognostic (5.11e-2)" "unprognostic (4.40e-3)" "unprognostic (4.40e-3)" "unprognostic (1.07e-2)" "unprognostic (5.85e-2)" "unprognostic (4.28e-2)" "unprognostic (4.02e-2)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "prognostic favorable (2.04e-4)" "prognostic favorable (1.17e-6)" "unprognostic (1.49e-2)" "unprognostic (2.78e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" UQCRC2 "QCR2, UQCR2" ENSG00000140740 "Ubiquinol-cytochrome c reductase core protein 2" P22695 16 21953288-21983660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 722.2;tongue: 933.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 645.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007998, HPA019146" Enhanced Enhanced Mitochondria NA NA 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Enzymes" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA007998: AB_1858648, HPA019146: AB_1858649" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.49e-3)" "unprognostic (3.35e-1)" "unprognostic (1.26e-2)" "unprognostic (6.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (2.43e-2)" "prognostic favorable (6.58e-9)" "unprognostic (2.33e-1)" "unprognostic (9.78e-3)" "unprognostic (4.67e-3)" "unprognostic (7.36e-2)" UQCRQ "QCR8, QP-C, UQCR7" ENSG00000164405 "Ubiquinol-cytochrome c reductase complex III subunit VII" O14949 5 132866630-132868847 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1301.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 5230.2;Hepatocytes: 5522.5;Proximal tubular cells: 3707.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046693, HPA053323" Approved Enhanced Mitochondria NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA046693: AB_10968453, HPA053323: AB_2682112" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (4.92e-2)" "prognostic favorable (4.23e-4)" "unprognostic (1.09e-1)" "unprognostic (9.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.45e-2)" "unprognostic (1.37e-1)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (3.49e-1)" "unprognostic (1.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (3.37e-2)"