The immune cell section - Expression profiles in human immune cells
The Immune Cell section contains single cell information on genome-wide RNA expression profiles of human protein-coding genes covering various B- and T-cells, monocytes, granulocytes and dendritic cells. The transcriptomics analysis covers 18 cell types isolated with cell sorting and includes classification based on specificity, distribution and expression cluster across all immune cells. More information about the specific content and the generation and analysis of the data in the section can be found in the Methods Summary.
- if a gene is enriched in a particular immune cell type (specificity)
- which genes have a similar expression profile across the immune cells (expression cluster)
- the catalogue of genes elevated in each of the immune cell types
IMMUNE CELL SPECIFICITY
All protein-coding genes have been classified according to the immune cell expression into genes elevated in at least one of the immune cells. In the figure, the number of cell lineage-elevated genes with highest expression in blood or lymphoid tissues is shown to the left and the cell lineage-enriched genes with highest expression in blood or lymphoid tissues to the right. All blood cell specific categories can be found here.