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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:50.0 nTPM
HPA:50.0 nTPM
GTEx:65.9 nTPM
FANTOM5:19.0 Scaled Tags Per Million
Pig:15.3 nTPM
Mouse:19.5 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 50.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 47.7
2586 Male, age 75, left hemisphere 66.4
2828 Female, age 72, unknown 49.7
1827 Male, age 72, unknown 47.2
2666 Male, age 74, left hemisphere 46.5
2411 Female, age 72, unknown 46.1
2019 Male, age 18, unknown 45.4
1870 Female, age 42, unknown 45.0
2219 Male, age 76, both hemispheres 44.5
1830 Male, age 51, unknown 43.3
1833 Male, age 53, unknown 43.3
Dorsal raphe nucleus
nTPM: 43.0
1828 Male, age 53, unknown 43.9
2047 Male, age 72, unknown 43.8
2750 Male, age 76, both hemispheres 43.7
2016 Female, age 72, unknown 42.2
2298 Female, age 72, unknown 41.2
Inferior colliculus
nTPM: 41.9
1890 Male, age 53, unknown 43.6
2097 Female, age 72, unknown 42.6
1848 Female, age 42, unknown 41.6
2849 Male, age 72, unknown 40.0
Median raphe nucleus
nTPM: 42.8
2220 Male, age 76, midline 42.8
Pedunculopontine tegmental nucleus
nTPM: 43.8
2334 Male, age 80, both hemispheres 45.3
2338 Male, age 61, both hemispheres 43.3
1921 Female, age 85, both hemispheres 42.7
Periaquaductal grey, anterior
nTPM: 50.0
2502 Female, age 75, unknown 51.5
1795 Male, age 51, unknown 49.7
1947 Male, age 18, unknown 48.7
Periaquaductal grey, dorsal
nTPM: 40.6
1831 Male, age 72, unknown 41.1
2464 Female, age 72, unknown 41.1
1840 Male, age 53, unknown 40.9
2850 Male, age 76, both hemispheres 39.2
Periaquaductal grey, lateral
nTPM: 40.8
2053 Male, age 18, unknown 41.9
2272 Male, age 74, both hemispheres 40.4
2140 Male, age 76, both hemispheres 40.1
Pretectal area
nTPM: 44.7
2007 Male, age 72, unknown 50.3
1816 Male, age 51, unknown 48.9
1817 Female, age 42, unknown 46.3
1944 Female, age 72, unknown 46.2
1815 Male, age 53, unknown 46.0
2407 Male, age 75, both hemispheres 44.2
2667 Female, age 75, unknown 43.3
2316 Male, age 76, right hemisphere 43.0
2273 Male, age 74, both hemispheres 42.5
2825 Male, age 18, unknown 41.7
2224 Female, age 72, unknown 39.7
Red nucleus
nTPM: 48.0
2503 Female, age 72, unknown 53.7
2785 Male, age 18, unknown 50.1
2227 Male, age 72, unknown 49.9
2769 Male, age 72, unknown 49.5
2588 Male, age 74, left hemisphere 48.5
1904 Male, age 53, unknown 48.4
2584 Male, age 75, left hemisphere 47.7
1821 Female, age 72, unknown 47.5
1954 Female, age 42, unknown 46.9
1865 Male, age 51, unknown 46.2
2725 Female, age 75, unknown 45.5
2823 Male, age 76, right hemisphere 41.7
Substantia nigra
nTPM: 49.2
1916 Female, age 42, unknown 59.4
1851 Male, age 51, unknown 54.6
2699 Male, age 18, unknown 50.1
2665 Male, age 74, both hemispheres 49.9
2583 Male, age 75, right hemisphere 49.6
1889 Female, age 72, unknown 48.6
1941 Male, age 53, unknown 47.0
2409 Female, age 72, unknown 45.7
2590 Female, age 75, unknown 45.5
2241 Male, age 72, unknown 41.7
Superior colliculus
nTPM: 45.5
2668 Female, age 75, unknown 51.2
2664 Male, age 75, both hemispheres 50.9
1796 Male, age 53, unknown 49.3
2261 Male, age 18, unknown 46.7
1913 Female, age 42, unknown 44.9
1995 Male, age 72, unknown 44.4
2087 Female, age 72, unknown 43.4
2587 Male, age 74, left hemisphere 43.0
1839 Male, age 51, unknown 41.6
1895 Male, age 76, right hemisphere 39.9
Ventral tegmental area
nTPM: 47.8
1915 Female, age 42, unknown 50.6
2410 Female, age 72, unknown 49.6
1942 Male, age 51, unknown 48.6
2218 Male, age 76, both hemispheres 47.1
2223 Female, age 72, unknown 46.6
2021 Male, age 53, unknown 44.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 65.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 65.9
Samples: 139

Max nTPM: 128.2
Min nTPM: 29.4
Std nTPM: 15.6
Median nTPM: 62.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 128.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 113.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 113.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 103.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 99.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 95.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 94.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 93.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 92.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 91.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 90.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 90.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 86.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 86.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 85.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 84.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 84.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 82.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 82.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 82.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 82.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 81.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 81.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 81.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 80.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 80.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 77.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 76.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 76.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 76.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 76.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 76.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 75.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 74.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 74.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 74.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 73.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 73.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 71.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 70.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 70.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 70.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 69.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 69.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 69.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 69.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 68.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 68.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 67.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 67.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 67.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 67.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 67.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 67.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 66.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 66.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 66.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 65.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 65.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 65.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 65.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 64.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 64.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 64.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 64.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 63.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 63.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 63.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 63.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 62.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 62.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 62.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 62.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 62.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 61.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 61.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 61.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 61.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 61.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 61.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 60.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 60.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 60.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 60.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 60.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 59.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 59.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 59.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 59.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 59.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 59.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 59.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 59.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 58.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 58.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 58.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 58.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 58.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 58.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 58.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 57.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 57.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 56.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 55.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 55.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 55.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 55.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 55.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 55.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 54.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 53.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 53.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 53.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 53.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 53.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 53.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 53.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 52.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 52.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 52.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 51.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 50.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 49.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 48.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 47.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 47.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 47.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 46.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 46.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 46.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 45.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 45.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 44.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 44.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 43.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 39.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 39.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 38.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 29.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 19.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 19.0
FF:10158-103A5 76 years, female 19.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 15.3
Pig sample Sample description nTPM
Midbrain
nTPM: 13.5
Samples: 4

Max nTPM: 17.6
Min nTPM: 10.0
Sample A Female 14.6
Sample B Female 10.0
Sample C Male 17.6
Sample D Male 11.8
Periaqueductal gray
nTPM: 8.6
Samples: 3

Max nTPM: 9.6
Min nTPM: 6.9
Sample B Female 9.6
Sample C Male 9.3
Sample D Male 6.9
Substantia nigra
nTPM: 13.3
Samples: 4

Max nTPM: 18.7
Min nTPM: 9.5
Sample A Female 18.7
Sample B Female 11.9
Sample C Male 13.1
Sample D Male 9.5
Superior colliculi
nTPM: 15.3
Samples: 4

Max nTPM: 16.7
Min nTPM: 12.9
Sample A Female 16.0
Sample B Female 16.7
Sample C Male 15.5
Sample D Male 12.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 19.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 19.5
Samples: 4

Max nTPM: 20.7
Min nTPM: 18.0
Sample A Male 20.2
Sample B Male 19.1
Sample C Female 18.0
Sample D Female 20.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
68546094 Antisense, RP_050120_02_A01, Mouse strain C57BL/6J (56 days, male) 0.0

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