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DKK3
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:46.8 nTPM
HPA:46.8 nTPM
FANTOM5:414.2 Scaled Tags Per Million
Pig:181.0 nTPM
Allen mouse:2.3 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 46.8
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 1.3
1984 Male, age 76, both hemispheres 5.5
2090 Male, age 80, both hemispheres 0.0
2188 Female, age 91, both hemispheres 0.0
2301 Female, age 85, both hemispheres 0.0
Dorsal cochlear nucleus
nTPM: 6.1
2058 Male, age 76, both hemispheres 19.2
2802 Male, age 74, right hemisphere 6.7
2370 Male, age 61, both hemispheres 4.6
2187 Female, age 91, both hemispheres 0.0
2378 Male, age 80, both hemispheres 0.0
Dorsal tegmental nucleus
nTPM: 7.2
2083 Male, age 80, both hemispheres 22.6
1936 Male, age 76, left hemisphere 6.5
2326 Male, age 74, both hemispheres 0.0
2358 Male, age 61, both hemispheres 0.0
Dorsolateral tegmental area
nTPM: 7.6
2654 Male, age 80, both hemispheres 16.4
2751 Female, age 85, both hemispheres 13.9
2141 Male, age 76, both hemispheres 6.6
2360 Male, age 74, both hemispheres 1.0
2337 Male, age 61, both hemispheres 0.0
Kolliker-Fuse nucleus
nTPM: 33.9
2315 Male, age 76, right hemisphere 75.9
2163 Male, age 80, both hemispheres 26.0
2793 Female, age 91, left hemisphere 0.0
Lateral lemniscal nuclei
nTPM: 18.5
2169 Male, age 76, both hemispheres 34.1
2746 Female, age 85, left hemisphere 34.1
2453 Male, age 74, right hemisphere 24.6
2036 Male, age 80, both hemispheres 0.0
2320 Female, age 91, left hemisphere 0.0
Lateral parabrachial nucleus
nTPM: 16.0
2139 Female, age 85, right hemisphere 64.1
2013 Male, age 80, both hemispheres 0.0
2790 Male, age 61, both hemispheres 0.0
2792 Male, age 76, both hemispheres 0.0
Lateral vestibular nucleus
nTPM: 12.7
2184 Male, age 76, both hemispheres 25.4
2311 Male, age 80, both hemispheres 0.0
Locus coeruleus
nTPM: 44.4
2014 Male, age 55, unknown 98.3
2317 Female, age 72, unknown 68.3
2123 Female, age 91, both hemispheres 42.5
2788 Male, age 74, unknown 37.6
1980 Male, age 76, both hemispheres 31.4
2720 Male, age 74, both hemispheres 23.2
2162 Male, age 80, both hemispheres 9.4
Medial olivary nucleus
nTPM: 46.8
2138 Female, age 91, both hemispheres 115.8
1962 Male, age 76, both hemispheres 53.9
2851 Male, age 80, both hemispheres 17.6
1943 Male, age 61, both hemispheres 0.0
Medial parabrachial nucleus
nTPM: 2.7
2170 Female, age 91, both hemispheres 7.4
2854 Male, age 80, both hemispheres 3.9
2156 Male, age 61, both hemispheres 2.0
2463 Female, age 85, right hemisphere 0.0
2786 Male, age 76, both hemispheres 0.0
Medial periolivary nuclei
nTPM: 29.9
2063 Male, age 76, both hemispheres 50.7
2171 Female, age 85, both hemispheres 50.6
2791 Male, age 74, right hemisphere 48.2
2081 Male, age 80, both hemispheres 0.0
2458 Female, age 91, both hemispheres 0.0
Motor facial nucleus
nTPM: 25.9
2062 Male, age 76, both hemispheres 69.8
2795 Female, age 91, both hemispheres 57.9
2365 Male, age 74, right hemisphere 27.9
2126 Male, age 61, both hemispheres 0.0
2327 Male, age 80, both hemispheres 0.0
2697 Female, age 85, both hemispheres 0.0
Motor trigeminal nucleus
nTPM: 2.1
2309 Male, age 76, both hemispheres 6.1
2079 Male, age 80, both hemispheres 4.0
2335 Male, age 61, both hemispheres 0.5
2321 Female, age 91, both hemispheres 0.0
2560 Male, age 74, both hemispheres 0.0
Nuclei of the trapezoid body
nTPM: 40.0
1983 Male, age 76, both hemispheres 70.8
2735 Female, age 85, both hemispheres 58.0
2159 Male, age 61, both hemispheres 57.6
2368 Female, age 91, both hemispheres 13.6
2166 Male, age 80, both hemispheres 0.0
Paramedian reticular nucleus
nTPM: 24.3
2057 Male, age 80, both hemispheres 34.9
2313 Male, age 61, both hemispheres 31.0
2050 Female, age 85, both hemispheres 27.2
2052 Male, age 76, both hemispheres 4.1
Pontine nuclei
nTPM: 39.4
2787 Female, age 85, both hemispheres 92.1
1863 Male, age 55, unknown 86.9
2727 Male, age 61, right hemisphere 49.6
2109 Female, age 72, unknown 48.0
1968 Male, age 76, left hemisphere 38.6
2115 Male, age 80, left hemisphere 0.0
2319 Female, age 91, both hemispheres 0.0
2454 Male, age 74, left hemisphere 0.0
Pontine raphe nucleus
nTPM: 29.9
2853 Male, age 76, midline 31.4
2122 Female, age 85, midline 28.4
Posteroventral cochlear nucleus
nTPM: 11.6
2070 Male, age 76, both hemispheres 31.6
2752 Female, age 85, both hemispheres 26.5
2135 Female, age 91, both hemispheres 0.0
2341 Male, age 80, both hemispheres 0.0
2371 Male, age 61, both hemispheres 0.0
Principal sensory trigeminal nucleus
nTPM: 23.6
2158 Male, age 61, both hemispheres 64.0
2324 Male, age 76, both hemispheres 20.6
2008 Male, age 80, left hemisphere 9.6
2367 Female, age 91, left hemisphere 0.0
Reticular pontine nucleus, caudal
nTPM: 13.9
2092 Male, age 76, both hemispheres 41.9
2332 Male, age 80, right hemisphere 13.9
2457 Female, age 91, both hemispheres 0.0
2559 Male, age 74, both hemispheres 0.0
Reticular pontine nucleus, oral
nTPM: 14.5
2012 Female, age 85, both hemispheres 31.2
1939 Male, age 80, both hemispheres 26.2
2167 Male, age 76, both hemispheres 15.0
2361 Male, age 74, both hemispheres 0.0
2366 Female, age 91, both hemispheres 0.0
Reticulotegmental nucleus
nTPM: 15.8
2325 Male, age 76, both hemispheres 31.1
2333 Male, age 80, both hemispheres 19.5
2322 Female, age 91, both hemispheres 12.8
2452 Male, age 74, both hemispheres 0.0
Spinal trigeminal nucleus, oral
nTPM: 15.2
1978 Male, age 76, both hemispheres 27.2
2737 Female, age 85, both hemispheres 18.4
2164 Male, age 80, both hemispheres 0.0
Subcoeruleus area
nTPM: 4.2
1958 Male, age 80, both hemispheres 19.6
2323 Female, age 91, left hemisphere 1.5
2089 Male, age 76, left hemisphere 0.0
2369 Female, age 85, left hemisphere 0.0
2451 Male, age 74, both hemispheres 0.0
Superior olive
nTPM: 17.7
1875 Female, age 85, both hemispheres 38.2
2364 Male, age 74, right hemisphere 37.5
2020 Male, age 76, both hemispheres 13.1
2329 Male, age 80, right hemisphere 0.0
2561 Female, age 91, both hemispheres 0.0
Superior vestibular nucleus
nTPM: 20.8
2061 Male, age 76, both hemispheres 44.2
2015 Male, age 80, both hemispheres 12.5
2383 Male, age 74, both hemispheres 5.9
Ventral periolivary nuclei
nTPM: 16.3
2165 Male, age 80, both hemispheres 37.4
2130 Female, age 85, both hemispheres 22.8
2023 Male, age 76, both hemispheres 5.0
2794 Female, age 91, left hemisphere 0.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 10.7
2449 Male, age 74, both hemispheres 27.3
2840 Female, age 85, both hemispheres 19.7
1959 Male, age 76, both hemispheres 17.5
2161 Male, age 80, both hemispheres 0.0
2359 Male, age 61, both hemispheres 0.0
2456 Female, age 91, both hemispheres 0.0

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 414.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 400.1
FF:10182-103D2 60 years, female 488.9
FF:10165-103B3 76 years, female 311.2
Pons
Scaled Tags Per Million: 414.2
FF:10033-101E6 18-54 years, mixed 414.2

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 181.0
Pig sample Sample description nTPM
Pons
nTPM: 181.0
Samples: 4

Max nTPM: 269.7
Min nTPM: 132.6
Sample A Female 269.7
Sample B Female 157.4
Sample C Male 164.2
Sample D Male 132.6

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.3
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 2.3
75492875 Antisense, RP_060523_03_E09, Mouse strain C57BL/6J (56 days, male) 3.0
75457693 Antisense, RP_060523_03_E09, Mouse strain C57BL/6J (56 days, male) 3.0
75457696 Antisense, RP_060523_03_H09, Mouse strain C57BL/6J (56 days, male) 2.8
75457694 Antisense, RP_060523_03_F09, Mouse strain C57BL/6J (56 days, male) 2.8
75457695 Antisense, RP_060523_03_G09, Mouse strain C57BL/6J (56 days, male) 2.6
75496227 Antisense, RP_060523_03_F09, Mouse strain C57BL/6J (56 days, male) 2.4
75496225 Antisense, RP_060523_03_E09, Mouse strain C57BL/6J (56 days, male) 2.4
75492876 Antisense, RP_060523_03_F09, Mouse strain C57BL/6J (56 days, male) 2.3
79556605 Antisense, RP_071018_02_B12, Mouse strain C57BL/6J (56 days, male) 2.2
75492877 Antisense, RP_060523_03_G09, Mouse strain C57BL/6J (56 days, male) 2.2
75496228 Antisense, RP_060523_03_G09, Mouse strain C57BL/6J (56 days, male) 2.1
75496238 Antisense, RP_060523_03_H09, Mouse strain C57BL/6J (56 days, male) 1.9
75496753 Antisense, RP_060523_03_F09, Mouse strain C57BL/6J (56 days, male) 1.8
75496764 Antisense, RP_060523_03_H09, Mouse strain C57BL/6J (56 days, male) 1.7
75492887 Antisense, RP_060523_03_H09, Mouse strain C57BL/6J (56 days, male) 1.7
69117401 Antisense, RP_050330_01_B02, Mouse strain C57BL/6J (56 days, male) 1.7
75496754 Antisense, RP_060523_03_G09, Mouse strain C57BL/6J (56 days, male) 1.6
75496742 Antisense, RP_060523_03_E09, Mouse strain C57BL/6J (56 days, male) 1.6
346 Antisense, RP_Baylor_103179, Mouse strain C57BL/6J (56 days, male) 1.3
347 Antisense, RP_Baylor_103179, Mouse strain C57BL/6J (56 days, male) 0.8

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