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LGALS1
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:576.1 nTPM
HPA:576.1 nTPM
GTEx:670.1 nTPM
FANTOM5:279.1 Scaled Tags Per Million
Pig:631.2 nTPM
Mouse:27.9 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 576.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 498.4
2019 Male, age 18, unknown 560.6
2828 Female, age 72, unknown 523.1
2411 Female, age 72, unknown 522.0
1827 Male, age 72, unknown 510.0
1870 Female, age 42, unknown 501.3
1830 Male, age 51, unknown 489.8
2666 Male, age 74, left hemisphere 489.2
2219 Male, age 76, both hemispheres 468.9
1833 Male, age 53, unknown 466.1
2586 Male, age 75, left hemisphere 453.3
Dorsal raphe nucleus
nTPM: 529.3
2750 Male, age 76, both hemispheres 588.1
1828 Male, age 53, unknown 544.6
2298 Female, age 72, unknown 524.5
2047 Male, age 72, unknown 524.3
2016 Female, age 72, unknown 464.9
Inferior colliculus
nTPM: 441.0
1848 Female, age 42, unknown 454.8
2097 Female, age 72, unknown 449.6
1890 Male, age 53, unknown 438.9
2849 Male, age 72, unknown 420.5
Median raphe nucleus
nTPM: 554.2
2220 Male, age 76, midline 554.2
Pedunculopontine tegmental nucleus
nTPM: 576.1
2338 Male, age 61, both hemispheres 634.7
2334 Male, age 80, both hemispheres 585.0
1921 Female, age 85, both hemispheres 508.5
Periaquaductal grey, anterior
nTPM: 540.1
1795 Male, age 51, unknown 574.1
1947 Male, age 18, unknown 551.6
2502 Female, age 75, unknown 494.6
Periaquaductal grey, dorsal
nTPM: 448.5
1831 Male, age 72, unknown 460.1
2850 Male, age 76, both hemispheres 457.9
2464 Female, age 72, unknown 451.4
1840 Male, age 53, unknown 424.7
Periaquaductal grey, lateral
nTPM: 477.0
2272 Male, age 74, both hemispheres 505.0
2053 Male, age 18, unknown 465.7
2140 Male, age 76, both hemispheres 460.2
Pretectal area
nTPM: 517.0
2007 Male, age 72, unknown 607.7
1817 Female, age 42, unknown 563.7
1816 Male, age 51, unknown 544.8
1944 Female, age 72, unknown 536.1
2273 Male, age 74, both hemispheres 534.2
1815 Male, age 53, unknown 513.9
2224 Female, age 72, unknown 495.5
2667 Female, age 75, unknown 493.1
2825 Male, age 18, unknown 474.6
2407 Male, age 75, both hemispheres 465.6
2316 Male, age 76, right hemisphere 458.1
Red nucleus
nTPM: 518.4
2785 Male, age 18, unknown 549.0
2823 Male, age 76, right hemisphere 534.8
1821 Female, age 72, unknown 531.1
1865 Male, age 51, unknown 528.3
2503 Female, age 72, unknown 520.0
2725 Female, age 75, unknown 519.0
2769 Male, age 72, unknown 516.1
1954 Female, age 42, unknown 515.1
2227 Male, age 72, unknown 511.4
2588 Male, age 74, left hemisphere 507.0
1904 Male, age 53, unknown 501.3
2584 Male, age 75, left hemisphere 487.1
Substantia nigra
nTPM: 502.8
1941 Male, age 53, unknown 597.5
1889 Female, age 72, unknown 541.1
1851 Male, age 51, unknown 529.8
2590 Female, age 75, unknown 513.1
1916 Female, age 42, unknown 509.3
2583 Male, age 75, right hemisphere 475.2
2409 Female, age 72, unknown 473.5
2665 Male, age 74, both hemispheres 472.1
2241 Male, age 72, unknown 468.0
2699 Male, age 18, unknown 448.1
Superior colliculus
nTPM: 490.1
2668 Female, age 75, unknown 525.6
2587 Male, age 74, left hemisphere 521.2
2261 Male, age 18, unknown 510.5
2087 Female, age 72, unknown 505.6
1796 Male, age 53, unknown 499.5
1913 Female, age 42, unknown 491.4
1995 Male, age 72, unknown 470.6
2664 Male, age 75, both hemispheres 465.4
1895 Male, age 76, right hemisphere 456.1
1839 Male, age 51, unknown 454.6
Ventral tegmental area
nTPM: 516.9
2223 Female, age 72, unknown 573.7
2410 Female, age 72, unknown 532.9
2218 Male, age 76, both hemispheres 525.9
2021 Male, age 53, unknown 501.5
1915 Female, age 42, unknown 496.3
1942 Male, age 51, unknown 470.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 670.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 670.1
Samples: 139

Max nTPM: 1424.2
Min nTPM: 198.5
Std nTPM: 223.7
Median nTPM: 642.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1424.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1365.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1337.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1240.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1221.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1192.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1184.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1135.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1116.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1102.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1093.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1000.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 998.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 978.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 977.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 949.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 945.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 864.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 861.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 840.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 836.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 828.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 816.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 815.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 803.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 798.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 792.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 788.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 781.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 779.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 776.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 775.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 775.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 768.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 765.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 755.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 748.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 746.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 744.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 742.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 741.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 734.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 733.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 730.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 726.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 723.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 721.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 719.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 717.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 714.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 712.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 704.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 700.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 691.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 690.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 685.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 684.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 683.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 680.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 680.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 678.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 668.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 665.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 661.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 660.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 656.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 655.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 650.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 647.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 642.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 642.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 641.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 638.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 633.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 631.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 621.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 614.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 612.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 611.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 609.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 605.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 604.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 604.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 599.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 596.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 596.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 590.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 583.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 583.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 568.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 567.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 566.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 566.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 562.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 557.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 551.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 550.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 548.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 547.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 547.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 539.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 535.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 533.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 531.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 530.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 529.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 524.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 519.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 517.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 510.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 510.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 499.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 498.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 497.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 490.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 490.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 489.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 471.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 466.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 460.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 452.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 446.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 444.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 440.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 424.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 403.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 397.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 392.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 373.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 372.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 365.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 364.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 346.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 346.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 321.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 317.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 314.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 297.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 198.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 279.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 279.1
FF:10158-103A5 76 years, female 279.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 631.2
Pig sample Sample description nTPM
Midbrain
nTPM: 414.4
Samples: 4

Max nTPM: 897.7
Min nTPM: 134.4
Sample A Female 897.7
Sample B Female 374.7
Sample C Male 250.8
Sample D Male 134.4
Periaqueductal gray
nTPM: 273.9
Samples: 3

Max nTPM: 321.8
Min nTPM: 207.1
Sample B Female 207.1
Sample C Male 321.8
Sample D Male 292.8
Substantia nigra
nTPM: 631.2
Samples: 4

Max nTPM: 958.8
Min nTPM: 243.8
Sample A Female 958.8
Sample B Female 739.5
Sample C Male 582.8
Sample D Male 243.8
Superior colliculi
nTPM: 320.1
Samples: 4

Max nTPM: 453.2
Min nTPM: 245.6
Sample A Female 263.2
Sample B Female 453.2
Sample C Male 318.3
Sample D Male 245.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 27.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 28.0
Samples: 4

Max nTPM: 32.4
Min nTPM: 24.0
Sample A Male 32.4
Sample B Male 26.6
Sample C Female 24.0
Sample D Female 28.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
70634417 Antisense, RP_050725_01_F12, Mouse strain C57BL/6J (56 days, male) 0.4
75651181 Antisense, RP_060518_01_C07, Mouse strain C57BL/6J (56 days, male) 0.3
79749622 Antisense, RP_071204_02_D11, Mouse strain C57BL/6J (56 days, male) 0.2

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