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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:149.4 nTPM
HPA:149.4 nTPM
GTEx:137.4 nTPM
FANTOM5:622.8 Scaled Tags Per Million
Pig:185.5 nTPM
Mouse:125.1 nTPM
Allen mouse:18.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 149.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 139.7
2411 Female, age 72, unknown 150.0
1830 Male, age 51, unknown 147.8
1833 Male, age 53, unknown 147.3
1870 Female, age 42, unknown 147.1
2019 Male, age 18, unknown 140.8
1827 Male, age 72, unknown 139.8
2828 Female, age 72, unknown 139.7
2666 Male, age 74, left hemisphere 133.7
2219 Male, age 76, both hemispheres 129.8
2586 Male, age 75, left hemisphere 121.1
Dorsal raphe nucleus
nTPM: 139.5
2750 Male, age 76, both hemispheres 147.5
2016 Female, age 72, unknown 143.3
1828 Male, age 53, unknown 136.8
2298 Female, age 72, unknown 135.4
2047 Male, age 72, unknown 134.6
Inferior colliculus
nTPM: 141.5
1848 Female, age 42, unknown 143.6
2849 Male, age 72, unknown 142.7
1890 Male, age 53, unknown 142.1
2097 Female, age 72, unknown 137.5
Median raphe nucleus
nTPM: 142.8
2220 Male, age 76, midline 142.8
Pedunculopontine tegmental nucleus
nTPM: 141.3
2338 Male, age 61, both hemispheres 146.1
1921 Female, age 85, both hemispheres 141.3
2334 Male, age 80, both hemispheres 136.5
Periaquaductal grey, anterior
nTPM: 133.6
1947 Male, age 18, unknown 140.2
1795 Male, age 51, unknown 132.4
2502 Female, age 75, unknown 128.2
Periaquaductal grey, dorsal
nTPM: 143.7
2850 Male, age 76, both hemispheres 148.7
2464 Female, age 72, unknown 143.5
1831 Male, age 72, unknown 142.1
1840 Male, age 53, unknown 140.2
Periaquaductal grey, lateral
nTPM: 149.4
2272 Male, age 74, both hemispheres 152.8
2140 Male, age 76, both hemispheres 150.5
2053 Male, age 18, unknown 145.0
Pretectal area
nTPM: 141.9
2273 Male, age 74, both hemispheres 157.7
2316 Male, age 76, right hemisphere 154.4
2667 Female, age 75, unknown 144.7
1815 Male, age 53, unknown 142.3
2825 Male, age 18, unknown 141.8
2224 Female, age 72, unknown 140.8
2407 Male, age 75, both hemispheres 140.6
2007 Male, age 72, unknown 136.1
1817 Female, age 42, unknown 135.4
1944 Female, age 72, unknown 134.9
1816 Male, age 51, unknown 132.4
Red nucleus
nTPM: 147.1
2823 Male, age 76, right hemisphere 155.2
1904 Male, age 53, unknown 152.6
1865 Male, age 51, unknown 151.9
2503 Female, age 72, unknown 150.7
2769 Male, age 72, unknown 148.8
1821 Female, age 72, unknown 148.3
2227 Male, age 72, unknown 147.9
1954 Female, age 42, unknown 147.7
2588 Male, age 74, left hemisphere 143.7
2785 Male, age 18, unknown 143.7
2725 Female, age 75, unknown 141.7
2584 Male, age 75, left hemisphere 133.2
Substantia nigra
nTPM: 136.3
2409 Female, age 72, unknown 150.9
2590 Female, age 75, unknown 142.4
2583 Male, age 75, right hemisphere 140.1
2699 Male, age 18, unknown 136.0
1889 Female, age 72, unknown 135.7
1851 Male, age 51, unknown 135.0
2241 Male, age 72, unknown 134.8
1941 Male, age 53, unknown 132.6
2665 Male, age 74, both hemispheres 129.8
1916 Female, age 42, unknown 125.4
Superior colliculus
nTPM: 141.5
1913 Female, age 42, unknown 156.1
1995 Male, age 72, unknown 150.1
1895 Male, age 76, right hemisphere 147.4
2668 Female, age 75, unknown 142.3
1839 Male, age 51, unknown 141.5
2587 Male, age 74, left hemisphere 140.9
2261 Male, age 18, unknown 138.7
2087 Female, age 72, unknown 138.1
1796 Male, age 53, unknown 134.8
2664 Male, age 75, both hemispheres 124.9
Ventral tegmental area
nTPM: 136.8
2410 Female, age 72, unknown 141.5
2223 Female, age 72, unknown 138.5
2021 Male, age 53, unknown 138.3
1942 Male, age 51, unknown 135.4
2218 Male, age 76, both hemispheres 134.5
1915 Female, age 42, unknown 132.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 137.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 137.4
Samples: 139

Max nTPM: 265.1
Min nTPM: 60.1
Std nTPM: 39.3
Median nTPM: 130.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 265.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 261.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 243.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 240.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 239.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 225.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 213.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 212.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 211.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 204.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 202.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 201.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 200.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 178.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 177.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 177.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 176.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 176.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 176.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 173.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 172.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 168.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 167.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 167.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 167.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 167.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 166.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 166.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 166.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 165.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 165.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 164.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 163.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 162.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 161.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 160.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 157.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 156.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 155.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 154.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 152.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 152.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 152.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 151.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 150.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 149.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 148.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 145.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 143.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 141.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 141.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 141.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 139.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 139.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 138.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 138.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 137.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 137.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 137.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 137.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 135.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 135.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 134.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 134.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 131.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 131.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 131.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 131.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 130.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 130.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 130.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 130.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 129.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 127.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 127.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 126.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 126.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 126.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 125.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 125.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 125.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 125.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 124.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 123.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 123.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 122.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 121.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 120.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 120.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 120.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 120.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 120.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 120.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 120.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 119.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 119.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 119.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 118.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 118.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 118.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 118.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 117.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 116.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 116.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 115.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 115.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 114.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 114.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 113.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 113.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 111.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 110.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 110.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 110.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 107.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 107.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 105.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 105.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 104.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 101.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 98.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 96.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 94.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 92.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 89.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 87.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 86.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 84.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 83.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 83.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 81.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 78.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 74.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 72.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 70.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 69.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 68.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 61.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 60.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 622.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 622.8
FF:10158-103A5 76 years, female 622.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 185.5
Pig sample Sample description nTPM
Midbrain
nTPM: 184.8
Samples: 4

Max nTPM: 217.7
Min nTPM: 168.0
Sample A Female 217.7
Sample B Female 184.4
Sample C Male 168.0
Sample D Male 168.9
Periaqueductal gray
nTPM: 183.9
Samples: 3

Max nTPM: 194.0
Min nTPM: 172.0
Sample B Female 185.6
Sample C Male 172.0
Sample D Male 194.0
Substantia nigra
nTPM: 185.5
Samples: 4

Max nTPM: 238.2
Min nTPM: 148.6
Sample A Female 148.6
Sample B Female 188.4
Sample C Male 166.8
Sample D Male 238.2
Superior colliculi
nTPM: 176.4
Samples: 4

Max nTPM: 189.4
Min nTPM: 162.8
Sample A Female 162.8
Sample B Female 189.4
Sample C Male 170.6
Sample D Male 182.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 125.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 125.1
Samples: 4

Max nTPM: 131.0
Min nTPM: 121.7
Sample A Male 123.9
Sample B Male 121.7
Sample C Female 131.0
Sample D Female 123.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 18.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 18.7
77620754 Antisense, RP_070129_03_F07, Mouse strain C57BL/6J (56 days, male) 18.7

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