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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:254.4 nTPM
HPA:254.4 nTPM
GTEx:459.5 nTPM
FANTOM5:1916.3 Scaled Tags Per Million
Pig:344.2 nTPM
Mouse:728.7 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 254.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 220.2
2219 Male, age 76, both hemispheres 322.4
2411 Female, age 72, unknown 297.7
1830 Male, age 51, unknown 249.8
1833 Male, age 53, unknown 243.1
1870 Female, age 42, unknown 240.5
2828 Female, age 72, unknown 202.1
2019 Male, age 18, unknown 200.1
1827 Male, age 72, unknown 177.4
2666 Male, age 74, left hemisphere 165.8
2586 Male, age 75, left hemisphere 103.4
Dorsal raphe nucleus
nTPM: 145.0
2750 Male, age 76, both hemispheres 305.8
1828 Male, age 53, unknown 143.4
2047 Male, age 72, unknown 95.9
2016 Female, age 72, unknown 90.2
2298 Female, age 72, unknown 89.9
Inferior colliculus
nTPM: 120.2
2849 Male, age 72, unknown 175.2
1848 Female, age 42, unknown 125.0
2097 Female, age 72, unknown 91.3
1890 Male, age 53, unknown 89.2
Median raphe nucleus
nTPM: 215.0
2220 Male, age 76, midline 215.0
Pedunculopontine tegmental nucleus
nTPM: 237.8
2334 Male, age 80, both hemispheres 271.2
2338 Male, age 61, both hemispheres 237.2
1921 Female, age 85, both hemispheres 204.9
Periaquaductal grey, anterior
nTPM: 120.9
1947 Male, age 18, unknown 135.9
1795 Male, age 51, unknown 131.8
2502 Female, age 75, unknown 95.1
Periaquaductal grey, dorsal
nTPM: 75.7
2464 Female, age 72, unknown 134.0
1831 Male, age 72, unknown 89.0
1840 Male, age 53, unknown 48.7
2850 Male, age 76, both hemispheres 31.1
Periaquaductal grey, lateral
nTPM: 94.3
2272 Male, age 74, both hemispheres 164.6
2053 Male, age 18, unknown 99.0
2140 Male, age 76, both hemispheres 19.4
Pretectal area
nTPM: 156.1
2407 Male, age 75, both hemispheres 213.8
1815 Male, age 53, unknown 192.6
2007 Male, age 72, unknown 187.3
1817 Female, age 42, unknown 180.6
1816 Male, age 51, unknown 157.9
1944 Female, age 72, unknown 147.4
2825 Male, age 18, unknown 146.3
2667 Female, age 75, unknown 144.2
2224 Female, age 72, unknown 119.7
2273 Male, age 74, both hemispheres 118.7
2316 Male, age 76, right hemisphere 109.0
Red nucleus
nTPM: 254.4
2823 Male, age 76, right hemisphere 315.5
2503 Female, age 72, unknown 274.0
1904 Male, age 53, unknown 267.2
1821 Female, age 72, unknown 261.1
2588 Male, age 74, left hemisphere 261.0
2227 Male, age 72, unknown 256.4
2769 Male, age 72, unknown 254.2
1865 Male, age 51, unknown 251.8
2785 Male, age 18, unknown 245.6
2584 Male, age 75, left hemisphere 236.6
2725 Female, age 75, unknown 233.0
1954 Female, age 42, unknown 196.7
Substantia nigra
nTPM: 193.6
1941 Male, age 53, unknown 243.5
1916 Female, age 42, unknown 239.6
2583 Male, age 75, right hemisphere 230.3
2590 Female, age 75, unknown 221.2
1851 Male, age 51, unknown 220.6
2699 Male, age 18, unknown 211.6
1889 Female, age 72, unknown 194.3
2409 Female, age 72, unknown 179.4
2241 Male, age 72, unknown 119.5
2665 Male, age 74, both hemispheres 76.0
Superior colliculus
nTPM: 182.5
1913 Female, age 42, unknown 275.0
2587 Male, age 74, left hemisphere 239.2
1995 Male, age 72, unknown 209.5
2668 Female, age 75, unknown 209.1
1796 Male, age 53, unknown 188.0
1895 Male, age 76, right hemisphere 183.7
1839 Male, age 51, unknown 164.1
2261 Male, age 18, unknown 145.9
2087 Female, age 72, unknown 145.8
2664 Male, age 75, both hemispheres 64.6
Ventral tegmental area
nTPM: 224.3
2223 Female, age 72, unknown 344.4
2410 Female, age 72, unknown 257.8
2218 Male, age 76, both hemispheres 254.8
1915 Female, age 42, unknown 187.3
1942 Male, age 51, unknown 152.5
2021 Male, age 53, unknown 148.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 459.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 459.5
Samples: 139

Max nTPM: 1323.0
Min nTPM: 94.3
Std nTPM: 234.9
Median nTPM: 429.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1323.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1290.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1226.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1026.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1013.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 960.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 945.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 922.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 913.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 904.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 901.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 824.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 821.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 798.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 776.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 757.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 755.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 725.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 692.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 675.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 654.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 630.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 622.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 618.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 618.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 608.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 595.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 587.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 586.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 584.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 579.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 551.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 547.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 544.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 542.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 538.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 536.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 534.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 533.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 525.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 521.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 519.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 518.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 518.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 517.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 516.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 512.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 511.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 509.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 504.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 501.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 498.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 473.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 469.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 466.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 464.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 463.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 463.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 461.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 457.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 456.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 454.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 447.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 447.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 445.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 440.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 433.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 431.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 431.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 429.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 427.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 423.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 404.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 402.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 401.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 400.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 396.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 391.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 388.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 387.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 384.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 383.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 374.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 369.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 369.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 367.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 365.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 357.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 351.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 347.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 342.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 340.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 338.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 338.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 317.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 315.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 314.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 311.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 311.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 304.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 304.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 304.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 302.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 299.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 295.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 289.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 288.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 288.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 286.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 276.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 275.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 271.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 269.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 256.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 252.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 251.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 245.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 243.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 243.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 234.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 231.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 227.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 219.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 211.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 206.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 205.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 199.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 197.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 195.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 192.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 181.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 176.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 165.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 161.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 159.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 153.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 103.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 94.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 94.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1916.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1916.3
FF:10158-103A5 76 years, female 1916.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 344.2
Pig sample Sample description nTPM
Midbrain
nTPM: 344.2
Samples: 4

Max nTPM: 679.5
Min nTPM: 193.9
Sample A Female 679.5
Sample B Female 290.9
Sample C Male 212.3
Sample D Male 193.9
Periaqueductal gray
nTPM: 210.8
Samples: 3

Max nTPM: 236.1
Min nTPM: 174.6
Sample B Female 236.1
Sample C Male 174.6
Sample D Male 221.8
Substantia nigra
nTPM: 318.0
Samples: 4

Max nTPM: 510.1
Min nTPM: 161.5
Sample A Female 317.4
Sample B Female 161.5
Sample C Male 282.9
Sample D Male 510.1
Superior colliculi
nTPM: 259.4
Samples: 4

Max nTPM: 340.4
Min nTPM: 117.4
Sample A Female 303.1
Sample B Female 117.4
Sample C Male 276.5
Sample D Male 340.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 728.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 728.7
Samples: 4

Max nTPM: 783.1
Min nTPM: 697.5
Sample A Male 783.1
Sample B Male 697.5
Sample C Female 709.8
Sample D Female 724.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
1081 Antisense, RP_Baylor_103091, Mouse strain C57BL/6J (56 days, male) 1.5
1082 Antisense, RP_Baylor_103091, Mouse strain C57BL/6J (56 days, male) 1.0
1083 Sense, RPS_Baylor_37062, Mouse strain C57BL/6J (56 days, male) 0.0

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