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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:126.5 nTPM
HPA:126.5 nTPM
GTEx:80.8 nTPM
FANTOM5:135.1 Scaled Tags Per Million
Pig:74.7 nTPM
Mouse:46.0 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 126.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 116.5
2586 Male, age 75, left hemisphere 126.5
2411 Female, age 72, unknown 122.5
2828 Female, age 72, unknown 122.3
1870 Female, age 42, unknown 121.6
2219 Male, age 76, both hemispheres 115.5
1827 Male, age 72, unknown 114.4
1833 Male, age 53, unknown 113.1
2019 Male, age 18, unknown 112.5
1830 Male, age 51, unknown 111.8
2666 Male, age 74, left hemisphere 104.4
Dorsal raphe nucleus
nTPM: 123.2
2750 Male, age 76, both hemispheres 130.7
2298 Female, age 72, unknown 127.7
2047 Male, age 72, unknown 125.6
2016 Female, age 72, unknown 119.0
1828 Male, age 53, unknown 112.9
Inferior colliculus
nTPM: 115.5
2097 Female, age 72, unknown 121.8
1890 Male, age 53, unknown 115.4
1848 Female, age 42, unknown 113.3
2849 Male, age 72, unknown 111.8
Median raphe nucleus
nTPM: 121.2
2220 Male, age 76, midline 121.2
Pedunculopontine tegmental nucleus
nTPM: 113.4
1921 Female, age 85, both hemispheres 120.7
2334 Male, age 80, both hemispheres 115.2
2338 Male, age 61, both hemispheres 104.3
Periaquaductal grey, anterior
nTPM: 126.5
1947 Male, age 18, unknown 128.6
1795 Male, age 51, unknown 126.5
2502 Female, age 75, unknown 124.3
Periaquaductal grey, dorsal
nTPM: 112.6
1840 Male, age 53, unknown 117.3
2850 Male, age 76, both hemispheres 111.9
2464 Female, age 72, unknown 111.7
1831 Male, age 72, unknown 109.7
Periaquaductal grey, lateral
nTPM: 123.7
2272 Male, age 74, both hemispheres 131.5
2140 Male, age 76, both hemispheres 123.2
2053 Male, age 18, unknown 116.3
Pretectal area
nTPM: 118.8
2273 Male, age 74, both hemispheres 134.6
2224 Female, age 72, unknown 124.0
2667 Female, age 75, unknown 121.4
2825 Male, age 18, unknown 119.5
2316 Male, age 76, right hemisphere 119.4
2007 Male, age 72, unknown 118.7
1944 Female, age 72, unknown 115.3
1816 Male, age 51, unknown 114.6
2407 Male, age 75, both hemispheres 114.4
1817 Female, age 42, unknown 113.3
1815 Male, age 53, unknown 112.0
Red nucleus
nTPM: 114.7
2227 Male, age 72, unknown 122.5
2503 Female, age 72, unknown 121.4
2769 Male, age 72, unknown 121.0
2785 Male, age 18, unknown 119.6
1904 Male, age 53, unknown 117.2
2588 Male, age 74, left hemisphere 114.3
1954 Female, age 42, unknown 113.3
2584 Male, age 75, left hemisphere 111.5
2725 Female, age 75, unknown 110.2
1865 Male, age 51, unknown 109.3
1821 Female, age 72, unknown 108.4
2823 Male, age 76, right hemisphere 107.5
Substantia nigra
nTPM: 114.2
1916 Female, age 42, unknown 125.4
1851 Male, age 51, unknown 124.4
1941 Male, age 53, unknown 119.5
1889 Female, age 72, unknown 116.0
2590 Female, age 75, unknown 114.7
2583 Male, age 75, right hemisphere 114.3
2241 Male, age 72, unknown 110.7
2699 Male, age 18, unknown 110.1
2665 Male, age 74, both hemispheres 105.7
2409 Female, age 72, unknown 101.6
Superior colliculus
nTPM: 115.7
1796 Male, age 53, unknown 124.9
2261 Male, age 18, unknown 122.1
2587 Male, age 74, left hemisphere 118.5
2668 Female, age 75, unknown 118.1
1913 Female, age 42, unknown 117.2
1839 Male, age 51, unknown 114.4
1895 Male, age 76, right hemisphere 111.6
2664 Male, age 75, both hemispheres 111.6
1995 Male, age 72, unknown 111.1
2087 Female, age 72, unknown 107.8
Ventral tegmental area
nTPM: 121.6
1942 Male, age 51, unknown 127.1
1915 Female, age 42, unknown 124.3
2410 Female, age 72, unknown 122.0
2218 Male, age 76, both hemispheres 120.4
2021 Male, age 53, unknown 118.4
2223 Female, age 72, unknown 117.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 80.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 80.8
Samples: 139

Max nTPM: 154.6
Min nTPM: 42.5
Std nTPM: 20.5
Median nTPM: 77.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 154.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 144.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 140.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 138.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 130.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 126.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 125.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 124.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 116.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 111.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 109.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 109.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 108.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 107.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 106.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 104.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 103.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 102.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 101.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 100.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 99.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 99.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 97.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 97.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 96.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 96.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 95.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 95.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 95.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 93.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 93.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 93.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 92.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 91.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 91.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 91.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 89.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 89.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 89.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 89.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 89.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 88.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 88.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 86.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 86.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 86.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 86.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 86.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 85.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 84.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 84.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 83.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 83.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 83.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 83.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 82.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 82.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 81.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 81.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 80.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 80.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 79.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 79.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 79.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 79.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 78.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 78.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 78.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 78.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 77.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 77.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 77.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 76.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 76.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 74.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 74.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 74.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 74.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 74.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 73.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 73.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 73.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 73.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 73.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 72.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 72.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 71.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 71.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 71.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 71.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 71.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 71.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 70.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 69.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 69.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 69.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 68.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 68.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 68.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 68.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 67.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 67.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 67.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 67.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 67.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 66.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 65.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 65.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 65.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 65.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 64.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 64.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 64.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 64.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 64.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 63.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 62.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 61.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 60.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 60.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 59.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 59.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 59.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 58.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 58.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 57.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 57.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 57.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 55.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 55.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 55.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 55.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 53.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 52.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 51.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 50.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 47.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 45.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 42.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 135.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 135.1
FF:10158-103A5 76 years, female 135.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 74.7
Pig sample Sample description nTPM
Midbrain
nTPM: 74.8
Samples: 4

Max nTPM: 93.0
Min nTPM: 60.1
Sample A Female 93.0
Sample B Female 60.1
Sample C Male 73.4
Sample D Male 72.5
Periaqueductal gray
nTPM: 59.8
Samples: 3

Max nTPM: 67.8
Min nTPM: 55.4
Sample B Female 55.4
Sample C Male 67.8
Sample D Male 56.1
Substantia nigra
nTPM: 64.9
Samples: 4

Max nTPM: 80.0
Min nTPM: 51.8
Sample A Female 80.0
Sample B Female 51.8
Sample C Male 73.4
Sample D Male 54.4
Superior colliculi
nTPM: 73.4
Samples: 4

Max nTPM: 82.4
Min nTPM: 64.5
Sample A Female 82.4
Sample B Female 76.6
Sample C Male 64.5
Sample D Male 69.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 46.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 46.0
Samples: 4

Max nTPM: 52.4
Min nTPM: 40.9
Sample A Male 52.4
Sample B Male 41.2
Sample C Female 40.9
Sample D Female 49.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
74581086 Antisense, RP_060215_02_E06, Mouse strain C57BL/6J (56 days, male) 0.5

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