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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:103.5 nTPM
HPA:103.5 nTPM
GTEx:153.9 nTPM
FANTOM5:29.5 Scaled Tags Per Million
Pig:31.8 nTPM
Mouse:5.4 nTPM
Allen mouse:1.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 103.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 101.7
2586 Male, age 75, left hemisphere 118.5
2666 Male, age 74, left hemisphere 113.0
2828 Female, age 72, unknown 107.4
1870 Female, age 42, unknown 104.4
1830 Male, age 51, unknown 98.0
1827 Male, age 72, unknown 96.7
1833 Male, age 53, unknown 96.5
2411 Female, age 72, unknown 95.4
2019 Male, age 18, unknown 94.7
2219 Male, age 76, both hemispheres 92.6
Dorsal raphe nucleus
nTPM: 96.4
2016 Female, age 72, unknown 100.1
1828 Male, age 53, unknown 97.1
2047 Male, age 72, unknown 96.3
2298 Female, age 72, unknown 94.4
2750 Male, age 76, both hemispheres 94.1
Inferior colliculus
nTPM: 99.2
2849 Male, age 72, unknown 102.7
1890 Male, age 53, unknown 99.9
2097 Female, age 72, unknown 97.5
1848 Female, age 42, unknown 96.5
Median raphe nucleus
nTPM: 96.5
2220 Male, age 76, midline 96.5
Pedunculopontine tegmental nucleus
nTPM: 95.5
2338 Male, age 61, both hemispheres 100.2
2334 Male, age 80, both hemispheres 96.0
1921 Female, age 85, both hemispheres 90.4
Periaquaductal grey, anterior
nTPM: 98.5
2502 Female, age 75, unknown 103.8
1795 Male, age 51, unknown 97.5
1947 Male, age 18, unknown 94.1
Periaquaductal grey, dorsal
nTPM: 93.5
1840 Male, age 53, unknown 95.7
1831 Male, age 72, unknown 95.5
2850 Male, age 76, both hemispheres 92.3
2464 Female, age 72, unknown 90.4
Periaquaductal grey, lateral
nTPM: 91.8
2053 Male, age 18, unknown 94.8
2140 Male, age 76, both hemispheres 92.0
2272 Male, age 74, both hemispheres 88.6
Pretectal area
nTPM: 93.3
2407 Male, age 75, both hemispheres 103.3
2825 Male, age 18, unknown 97.0
2316 Male, age 76, right hemisphere 95.9
2007 Male, age 72, unknown 93.7
2667 Female, age 75, unknown 93.3
1815 Male, age 53, unknown 92.1
1817 Female, age 42, unknown 91.7
1816 Male, age 51, unknown 90.9
2224 Female, age 72, unknown 90.8
2273 Male, age 74, both hemispheres 89.4
1944 Female, age 72, unknown 87.9
Red nucleus
nTPM: 103.5
2584 Male, age 75, left hemisphere 116.3
2503 Female, age 72, unknown 111.9
2227 Male, age 72, unknown 109.8
2769 Male, age 72, unknown 108.3
1865 Male, age 51, unknown 104.6
1904 Male, age 53, unknown 103.0
2725 Female, age 75, unknown 100.9
2785 Male, age 18, unknown 99.8
1821 Female, age 72, unknown 98.8
2588 Male, age 74, left hemisphere 97.9
1954 Female, age 42, unknown 96.8
2823 Male, age 76, right hemisphere 93.8
Substantia nigra
nTPM: 96.0
2665 Male, age 74, both hemispheres 107.0
2699 Male, age 18, unknown 105.2
2583 Male, age 75, right hemisphere 101.2
1851 Male, age 51, unknown 98.8
1916 Female, age 42, unknown 95.6
1941 Male, age 53, unknown 95.1
2590 Female, age 75, unknown 94.7
1889 Female, age 72, unknown 91.1
2409 Female, age 72, unknown 86.4
2241 Male, age 72, unknown 84.6
Superior colliculus
nTPM: 99.3
2664 Male, age 75, both hemispheres 121.1
1913 Female, age 42, unknown 102.0
1995 Male, age 72, unknown 100.5
2587 Male, age 74, left hemisphere 99.6
1796 Male, age 53, unknown 99.3
1839 Male, age 51, unknown 97.2
2668 Female, age 75, unknown 95.6
2261 Male, age 18, unknown 94.8
2087 Female, age 72, unknown 93.0
1895 Male, age 76, right hemisphere 90.0
Ventral tegmental area
nTPM: 97.2
1915 Female, age 42, unknown 101.8
2223 Female, age 72, unknown 101.5
1942 Male, age 51, unknown 99.4
2021 Male, age 53, unknown 97.6
2218 Male, age 76, both hemispheres 92.7
2410 Female, age 72, unknown 90.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 153.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 153.9
Samples: 139

Max nTPM: 422.6
Min nTPM: 44.9
Std nTPM: 53.7
Median nTPM: 150.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 422.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 320.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 295.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 265.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 258.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 257.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 246.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 238.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 233.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 233.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 230.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 229.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 223.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 220.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 218.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 217.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 217.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 216.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 216.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 208.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 206.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 201.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 201.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 200.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 198.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 198.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 195.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 193.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 192.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 191.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 188.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 185.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 185.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 183.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 180.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 180.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 180.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 178.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 175.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 172.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 171.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 169.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 167.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 167.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 166.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 165.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 165.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 164.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 164.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 163.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 163.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 161.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 159.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 158.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 158.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 158.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 156.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 156.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 155.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 155.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 155.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 155.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 154.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 154.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 153.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 153.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 152.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 151.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 151.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 150.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 150.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 148.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 148.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 146.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 146.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 144.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 141.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 138.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 138.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 137.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 137.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 137.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 136.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 134.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 134.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 134.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 132.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 130.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 129.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 128.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 128.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 127.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 127.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 126.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 126.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 123.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 123.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 122.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 121.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 119.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 119.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 118.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 118.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 117.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 116.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 115.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 114.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 112.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 111.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 111.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 110.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 109.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 109.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 107.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 107.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 106.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 105.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 103.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 103.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 101.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 100.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 99.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 98.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 98.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 97.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 93.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 93.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 90.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 90.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 89.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 88.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 87.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 87.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 83.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 74.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 68.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 64.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 63.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 44.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 29.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 29.5
FF:10158-103A5 76 years, female 29.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 31.8
Pig sample Sample description nTPM
Midbrain
nTPM: 30.6
Samples: 4

Max nTPM: 45.1
Min nTPM: 23.4
Sample A Female 45.1
Sample B Female 27.6
Sample C Male 23.4
Sample D Male 26.2
Periaqueductal gray
nTPM: 23.6
Samples: 3

Max nTPM: 25.4
Min nTPM: 20.8
Sample B Female 25.4
Sample C Male 24.7
Sample D Male 20.8
Substantia nigra
nTPM: 29.0
Samples: 4

Max nTPM: 34.0
Min nTPM: 24.3
Sample A Female 34.0
Sample B Female 30.0
Sample C Male 24.3
Sample D Male 27.7
Superior colliculi
nTPM: 31.9
Samples: 4

Max nTPM: 36.5
Min nTPM: 25.5
Sample A Female 36.5
Sample B Female 35.6
Sample C Male 25.5
Sample D Male 29.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 5.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 5.4
Samples: 4

Max nTPM: 5.5
Min nTPM: 5.4
Sample A Male 5.4
Sample B Male 5.5
Sample C Female 5.4
Sample D Female 5.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.8
68193067 Antisense, RP_040914_01_D05, Mouse strain C57BL/6J (56 days, male) 1.8

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