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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:7.7 nTPM
HPA:7.7 nTPM
GTEx:11.0 nTPM
FANTOM5:64.6 Scaled Tags Per Million
Pig:10.0 nTPM
Mouse:5.7 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 7.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 7.7
2586 Male, age 75, left hemisphere 18.5
2219 Male, age 76, both hemispheres 10.2
2828 Female, age 72, unknown 9.8
2666 Male, age 74, left hemisphere 7.7
1827 Male, age 72, unknown 6.4
1833 Male, age 53, unknown 5.9
1830 Male, age 51, unknown 5.5
2019 Male, age 18, unknown 5.5
1870 Female, age 42, unknown 4.6
2411 Female, age 72, unknown 3.5
Dorsal raphe nucleus
nTPM: 4.5
2750 Male, age 76, both hemispheres 6.0
1828 Male, age 53, unknown 5.0
2047 Male, age 72, unknown 4.9
2016 Female, age 72, unknown 4.4
2298 Female, age 72, unknown 2.1
Inferior colliculus
nTPM: 5.2
2849 Male, age 72, unknown 7.7
1890 Male, age 53, unknown 5.8
1848 Female, age 42, unknown 3.9
2097 Female, age 72, unknown 3.3
Median raphe nucleus
nTPM: 5.2
2220 Male, age 76, midline 5.2
Pedunculopontine tegmental nucleus
nTPM: 4.0
1921 Female, age 85, both hemispheres 5.5
2334 Male, age 80, both hemispheres 4.1
2338 Male, age 61, both hemispheres 2.6
Periaquaductal grey, anterior
nTPM: 7.5
1795 Male, age 51, unknown 8.3
2502 Female, age 75, unknown 8.1
1947 Male, age 18, unknown 6.1
Periaquaductal grey, dorsal
nTPM: 5.1
2850 Male, age 76, both hemispheres 5.8
2464 Female, age 72, unknown 5.3
1831 Male, age 72, unknown 5.1
1840 Male, age 53, unknown 4.0
Periaquaductal grey, lateral
nTPM: 6.1
2140 Male, age 76, both hemispheres 7.8
2053 Male, age 18, unknown 5.6
2272 Male, age 74, both hemispheres 4.8
Pretectal area
nTPM: 6.4
2407 Male, age 75, both hemispheres 9.2
2316 Male, age 76, right hemisphere 8.6
2007 Male, age 72, unknown 7.7
1816 Male, age 51, unknown 7.5
1944 Female, age 72, unknown 6.6
2825 Male, age 18, unknown 6.4
1815 Male, age 53, unknown 6.1
2667 Female, age 75, unknown 6.1
1817 Female, age 42, unknown 5.5
2224 Female, age 72, unknown 4.1
2273 Male, age 74, both hemispheres 2.7
Red nucleus
nTPM: 6.7
2584 Male, age 75, left hemisphere 12.7
2785 Male, age 18, unknown 9.0
2588 Male, age 74, left hemisphere 8.4
2769 Male, age 72, unknown 8.1
2227 Male, age 72, unknown 7.9
2823 Male, age 76, right hemisphere 7.5
1904 Male, age 53, unknown 5.7
2503 Female, age 72, unknown 5.6
2725 Female, age 75, unknown 5.1
1954 Female, age 42, unknown 4.5
1865 Male, age 51, unknown 4.3
1821 Female, age 72, unknown 1.2
Substantia nigra
nTPM: 4.6
2583 Male, age 75, right hemisphere 9.4
2665 Male, age 74, both hemispheres 8.1
2590 Female, age 75, unknown 6.1
1941 Male, age 53, unknown 4.9
1916 Female, age 42, unknown 4.6
2699 Male, age 18, unknown 4.6
1889 Female, age 72, unknown 4.1
1851 Male, age 51, unknown 4.0
2409 Female, age 72, unknown 0.3
2241 Male, age 72, unknown 0.0
Superior colliculus
nTPM: 7.3
2664 Male, age 75, both hemispheres 14.4
1796 Male, age 53, unknown 8.2
2261 Male, age 18, unknown 8.1
1913 Female, age 42, unknown 7.5
1839 Male, age 51, unknown 6.8
1995 Male, age 72, unknown 6.8
2087 Female, age 72, unknown 6.3
2668 Female, age 75, unknown 6.2
2587 Male, age 74, left hemisphere 4.9
1895 Male, age 76, right hemisphere 3.6
Ventral tegmental area
nTPM: 5.4
1942 Male, age 51, unknown 8.1
2223 Female, age 72, unknown 5.9
2021 Male, age 53, unknown 5.8
2218 Male, age 76, both hemispheres 5.7
1915 Female, age 42, unknown 4.4
2410 Female, age 72, unknown 2.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 11.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 11.0
Samples: 139

Max nTPM: 20.0
Min nTPM: 5.8
Std nTPM: 2.3
Median nTPM: 11.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 20.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 19.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 17.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 16.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 15.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 15.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 14.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 14.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 14.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 14.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 14.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 14.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 14.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 13.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 13.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 13.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 13.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 13.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 13.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 13.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 13.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 13.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 13.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 13.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 13.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 12.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 12.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 12.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 12.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 12.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 12.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 12.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 12.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 12.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 12.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 12.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 12.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 12.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 12.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 12.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 12.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 12.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 12.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 12.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 12.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 12.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 12.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 12.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 12.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 12.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 11.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 11.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 11.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 11.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 11.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 11.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 11.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 11.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 11.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 11.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 11.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 11.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 11.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 11.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 11.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 11.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 11.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 11.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 11.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 11.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 11.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 11.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 10.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 10.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 10.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 10.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 10.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 10.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 10.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 10.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 10.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 10.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 10.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 10.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 10.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 10.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 10.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 10.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 10.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 10.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 10.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 10.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 10.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 9.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 9.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 9.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 9.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 9.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 9.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 9.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 9.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 9.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 9.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 9.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 9.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 9.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 9.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 9.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 9.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 9.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 8.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 8.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 8.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 8.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 8.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 8.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 8.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 8.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 8.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 8.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 8.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 8.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 8.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 8.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 8.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 8.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 8.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 8.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 8.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 8.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 7.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 7.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 7.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 7.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 6.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 6.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 6.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 6.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 5.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 64.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 64.6
FF:10158-103A5 76 years, female 64.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 10.0
Pig sample Sample description nTPM
Midbrain
nTPM: 9.9
Samples: 4

Max nTPM: 10.8
Min nTPM: 8.8
Sample A Female 9.5
Sample B Female 8.8
Sample C Male 10.8
Sample D Male 10.3
Periaqueductal gray
nTPM: 9.2
Samples: 3

Max nTPM: 9.7
Min nTPM: 8.7
Sample B Female 8.7
Sample C Male 9.1
Sample D Male 9.7
Substantia nigra
nTPM: 9.7
Samples: 4

Max nTPM: 11.3
Min nTPM: 8.1
Sample A Female 8.1
Sample B Female 9.5
Sample C Male 9.7
Sample D Male 11.3
Superior colliculi
nTPM: 10.0
Samples: 4

Max nTPM: 11.5
Min nTPM: 9.0
Sample A Female 9.0
Sample B Female 9.8
Sample C Male 9.7
Sample D Male 11.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 5.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 5.8
Samples: 4

Max nTPM: 6.7
Min nTPM: 4.9
Sample A Male 6.7
Sample B Male 5.8
Sample C Female 5.6
Sample D Female 4.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
71210406 Antisense, RP_050810_04_B05, Mouse strain C57BL/6J (56 days, male) 0.1

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