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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:87.2 nTPM
HPA:87.2 nTPM
GTEx:103.7 nTPM
FANTOM5:243.3 Scaled Tags Per Million
Pig:113.5 nTPM
Mouse:154.3 nTPM
Allen mouse:7.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 87.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 71.5
1827 Male, age 72, unknown 75.4
2411 Female, age 72, unknown 75.4
2828 Female, age 72, unknown 74.7
2219 Male, age 76, both hemispheres 73.0
1870 Female, age 42, unknown 72.9
2019 Male, age 18, unknown 71.8
1833 Male, age 53, unknown 70.8
1830 Male, age 51, unknown 68.5
2666 Male, age 74, left hemisphere 68.0
2586 Male, age 75, left hemisphere 64.1
Dorsal raphe nucleus
nTPM: 78.9
2298 Female, age 72, unknown 86.9
2750 Male, age 76, both hemispheres 80.5
2047 Male, age 72, unknown 80.2
1828 Male, age 53, unknown 74.9
2016 Female, age 72, unknown 71.8
Inferior colliculus
nTPM: 71.4
2097 Female, age 72, unknown 79.0
1890 Male, age 53, unknown 70.3
1848 Female, age 42, unknown 69.1
2849 Male, age 72, unknown 67.2
Median raphe nucleus
nTPM: 87.2
2220 Male, age 76, midline 87.2
Pedunculopontine tegmental nucleus
nTPM: 78.0
2334 Male, age 80, both hemispheres 83.8
2338 Male, age 61, both hemispheres 75.8
1921 Female, age 85, both hemispheres 74.4
Periaquaductal grey, anterior
nTPM: 75.9
1795 Male, age 51, unknown 77.0
2502 Female, age 75, unknown 76.3
1947 Male, age 18, unknown 74.4
Periaquaductal grey, dorsal
nTPM: 74.1
1840 Male, age 53, unknown 77.9
2850 Male, age 76, both hemispheres 77.4
1831 Male, age 72, unknown 71.6
2464 Female, age 72, unknown 69.4
Periaquaductal grey, lateral
nTPM: 73.1
2053 Male, age 18, unknown 75.0
2140 Male, age 76, both hemispheres 72.9
2272 Male, age 74, both hemispheres 71.6
Pretectal area
nTPM: 77.8
1816 Male, age 51, unknown 84.2
1944 Female, age 72, unknown 84.1
1817 Female, age 42, unknown 81.4
1815 Male, age 53, unknown 81.3
2007 Male, age 72, unknown 79.0
2273 Male, age 74, both hemispheres 78.4
2224 Female, age 72, unknown 77.4
2407 Male, age 75, both hemispheres 75.1
2667 Female, age 75, unknown 73.2
2825 Male, age 18, unknown 73.1
2316 Male, age 76, right hemisphere 68.3
Red nucleus
nTPM: 71.8
2725 Female, age 75, unknown 81.8
1821 Female, age 72, unknown 76.2
1954 Female, age 42, unknown 73.4
1904 Male, age 53, unknown 72.8
1865 Male, age 51, unknown 72.0
2584 Male, age 75, left hemisphere 71.2
2785 Male, age 18, unknown 71.1
2503 Female, age 72, unknown 70.8
2227 Male, age 72, unknown 70.6
2823 Male, age 76, right hemisphere 69.3
2769 Male, age 72, unknown 68.5
2588 Male, age 74, left hemisphere 63.8
Substantia nigra
nTPM: 83.2
2241 Male, age 72, unknown 96.2
1916 Female, age 42, unknown 94.1
1851 Male, age 51, unknown 88.0
2409 Female, age 72, unknown 86.1
2665 Male, age 74, both hemispheres 83.2
1889 Female, age 72, unknown 81.4
2699 Male, age 18, unknown 79.4
1941 Male, age 53, unknown 76.9
2590 Female, age 75, unknown 75.8
2583 Male, age 75, right hemisphere 71.2
Superior colliculus
nTPM: 72.9
2087 Female, age 72, unknown 83.6
2261 Male, age 18, unknown 79.0
1796 Male, age 53, unknown 75.1
1913 Female, age 42, unknown 72.9
2587 Male, age 74, left hemisphere 72.6
2668 Female, age 75, unknown 72.3
2664 Male, age 75, both hemispheres 70.3
1995 Male, age 72, unknown 68.2
1895 Male, age 76, right hemisphere 67.6
1839 Male, age 51, unknown 67.2
Ventral tegmental area
nTPM: 80.6
2218 Male, age 76, both hemispheres 84.0
1915 Female, age 42, unknown 82.1
2410 Female, age 72, unknown 80.7
2223 Female, age 72, unknown 79.9
2021 Male, age 53, unknown 78.6
1942 Male, age 51, unknown 78.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 103.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 103.7
Samples: 139

Max nTPM: 169.3
Min nTPM: 48.5
Std nTPM: 24.1
Median nTPM: 99.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 169.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 167.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 159.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 159.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 157.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 154.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 152.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 149.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 146.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 144.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 142.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 142.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 141.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 141.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 139.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 138.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 136.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 136.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 135.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 134.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 133.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 131.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 129.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 126.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 124.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 122.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 121.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 121.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 121.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 120.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 120.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 117.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 117.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 117.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 117.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 117.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 116.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 115.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 115.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 114.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 114.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 112.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 111.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 111.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 111.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 111.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 111.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 110.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 110.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 109.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 108.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 107.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 107.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 107.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 107.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 106.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 106.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 105.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 105.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 103.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 102.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 102.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 102.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 101.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 101.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 101.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 100.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 100.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 100.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 99.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 99.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 99.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 98.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 98.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 98.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 97.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 97.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 97.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 96.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 96.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 96.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 96.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 96.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 96.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 95.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 94.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 94.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 92.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 92.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 92.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 92.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 92.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 91.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 91.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 90.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 90.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 90.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 90.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 89.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 89.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 89.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 88.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 88.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 87.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 87.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 87.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 86.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 86.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 86.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 85.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 84.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 82.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 81.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 81.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 80.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 80.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 80.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 79.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 79.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 79.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 79.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 77.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 74.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 74.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 73.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 73.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 73.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 73.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 72.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 71.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 70.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 69.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 69.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 69.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 67.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 64.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 64.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 62.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 48.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 243.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 243.3
FF:10158-103A5 76 years, female 243.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 113.5
Pig sample Sample description nTPM
Midbrain
nTPM: 113.5
Samples: 4

Max nTPM: 157.5
Min nTPM: 91.4
Sample A Female 108.3
Sample B Female 91.4
Sample C Male 157.5
Sample D Male 96.7
Periaqueductal gray
nTPM: 76.5
Samples: 3

Max nTPM: 86.4
Min nTPM: 68.5
Sample B Female 68.5
Sample C Male 86.4
Sample D Male 74.6
Substantia nigra
nTPM: 90.7
Samples: 4

Max nTPM: 118.0
Min nTPM: 59.5
Sample A Female 118.0
Sample B Female 82.5
Sample C Male 102.7
Sample D Male 59.5
Superior colliculi
nTPM: 105.8
Samples: 4

Max nTPM: 149.6
Min nTPM: 73.6
Sample A Female 102.8
Sample B Female 73.6
Sample C Male 149.6
Sample D Male 97.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 154.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 154.3
Samples: 4

Max nTPM: 158.0
Min nTPM: 151.7
Sample A Male 151.8
Sample B Male 155.8
Sample C Female 158.0
Sample D Female 151.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.9
71608391 Antisense, RP_050927_01_F08, Mouse strain C57BL/6J (56 days, male) 10.4
356490 Antisense, RP_040617_02_F05, Mouse strain C57BL/6J (56 days, male) 5.5

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