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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:118.1 nTPM
HPA:118.1 nTPM
GTEx:115.9 nTPM
FANTOM5:85.8 Scaled Tags Per Million
Pig:61.1 nTPM
Mouse:200.9 nTPM
Allen mouse:2.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 118.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 110.3
2411 Female, age 72, unknown 117.1
2019 Male, age 18, unknown 116.5
1870 Female, age 42, unknown 113.5
1827 Male, age 72, unknown 113.1
2666 Male, age 74, left hemisphere 110.4
2219 Male, age 76, both hemispheres 109.9
1833 Male, age 53, unknown 107.3
1830 Male, age 51, unknown 106.4
2828 Female, age 72, unknown 104.4
2586 Male, age 75, left hemisphere 104.3
Dorsal raphe nucleus
nTPM: 113.1
2047 Male, age 72, unknown 117.5
2298 Female, age 72, unknown 117.4
2750 Male, age 76, both hemispheres 115.0
1828 Male, age 53, unknown 109.0
2016 Female, age 72, unknown 106.7
Inferior colliculus
nTPM: 108.7
2097 Female, age 72, unknown 112.5
1890 Male, age 53, unknown 109.9
1848 Female, age 42, unknown 108.2
2849 Male, age 72, unknown 104.3
Median raphe nucleus
nTPM: 118.1
2220 Male, age 76, midline 118.1
Pedunculopontine tegmental nucleus
nTPM: 114.2
2334 Male, age 80, both hemispheres 117.5
1921 Female, age 85, both hemispheres 112.9
2338 Male, age 61, both hemispheres 112.4
Periaquaductal grey, anterior
nTPM: 111.6
1947 Male, age 18, unknown 113.9
2502 Female, age 75, unknown 112.6
1795 Male, age 51, unknown 108.5
Periaquaductal grey, dorsal
nTPM: 106.6
1840 Male, age 53, unknown 109.7
2464 Female, age 72, unknown 107.0
1831 Male, age 72, unknown 105.0
2850 Male, age 76, both hemispheres 104.6
Periaquaductal grey, lateral
nTPM: 105.1
2272 Male, age 74, both hemispheres 107.0
2053 Male, age 18, unknown 105.6
2140 Male, age 76, both hemispheres 102.6
Pretectal area
nTPM: 112.1
1816 Male, age 51, unknown 121.4
2007 Male, age 72, unknown 120.3
1817 Female, age 42, unknown 117.9
1944 Female, age 72, unknown 115.4
1815 Male, age 53, unknown 114.2
2224 Female, age 72, unknown 110.8
2407 Male, age 75, both hemispheres 109.5
2825 Male, age 18, unknown 107.2
2667 Female, age 75, unknown 106.1
2273 Male, age 74, both hemispheres 106.0
2316 Male, age 76, right hemisphere 104.0
Red nucleus
nTPM: 111.0
1821 Female, age 72, unknown 118.1
2588 Male, age 74, left hemisphere 117.4
2725 Female, age 75, unknown 116.5
2503 Female, age 72, unknown 113.6
2785 Male, age 18, unknown 112.3
1865 Male, age 51, unknown 110.4
1954 Female, age 42, unknown 110.2
1904 Male, age 53, unknown 109.3
2769 Male, age 72, unknown 106.6
2584 Male, age 75, left hemisphere 105.9
2823 Male, age 76, right hemisphere 105.8
2227 Male, age 72, unknown 105.4
Substantia nigra
nTPM: 115.9
2241 Male, age 72, unknown 123.5
1851 Male, age 51, unknown 121.4
1916 Female, age 42, unknown 120.8
1889 Female, age 72, unknown 118.5
1941 Male, age 53, unknown 115.7
2590 Female, age 75, unknown 114.9
2665 Male, age 74, both hemispheres 114.7
2409 Female, age 72, unknown 114.4
2699 Male, age 18, unknown 108.7
2583 Male, age 75, right hemisphere 105.9
Superior colliculus
nTPM: 108.8
2587 Male, age 74, left hemisphere 115.9
2087 Female, age 72, unknown 113.1
1796 Male, age 53, unknown 111.2
1895 Male, age 76, right hemisphere 109.6
2261 Male, age 18, unknown 109.4
2668 Female, age 75, unknown 108.6
1913 Female, age 42, unknown 108.3
1839 Male, age 51, unknown 107.1
1995 Male, age 72, unknown 104.4
2664 Male, age 75, both hemispheres 100.9
Ventral tegmental area
nTPM: 112.6
2410 Female, age 72, unknown 120.3
1915 Female, age 42, unknown 114.2
2223 Female, age 72, unknown 112.8
2021 Male, age 53, unknown 110.7
2218 Male, age 76, both hemispheres 109.8
1942 Male, age 51, unknown 108.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 115.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 115.9
Samples: 139

Max nTPM: 346.2
Min nTPM: 69.2
Std nTPM: 39.1
Median nTPM: 106.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 346.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 273.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 261.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 225.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 204.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 202.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 190.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 187.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 185.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 181.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 179.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 168.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 164.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 162.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 156.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 156.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 155.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 152.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 144.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 143.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 138.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 136.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 135.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 133.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 128.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 128.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 128.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 128.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 126.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 126.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 126.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 126.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 125.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 124.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 123.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 122.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 122.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 121.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 121.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 120.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 119.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 118.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 118.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 116.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 116.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 115.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 115.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 113.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 113.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 113.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 112.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 112.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 112.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 111.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 111.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 111.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 111.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 110.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 110.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 110.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 109.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 109.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 108.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 108.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 108.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 107.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 107.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 107.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 107.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 106.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 106.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 105.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 105.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 105.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 105.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 104.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 104.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 103.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 102.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 102.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 101.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 101.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 100.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 100.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 99.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 99.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 99.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 99.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 99.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 98.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 98.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 98.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 98.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 97.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 97.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 97.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 97.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 97.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 96.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 96.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 96.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 95.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 95.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 95.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 94.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 93.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 93.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 92.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 92.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 92.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 92.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 92.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 90.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 90.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 90.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 89.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 88.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 86.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 86.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 86.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 85.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 85.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 85.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 85.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 84.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 84.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 83.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 83.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 82.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 82.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 81.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 80.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 80.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 77.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 74.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 74.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 70.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 69.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 69.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 85.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 85.8
FF:10158-103A5 76 years, female 85.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 61.1
Pig sample Sample description nTPM
Midbrain
nTPM: 61.1
Samples: 4

Max nTPM: 79.3
Min nTPM: 49.8
Sample A Female 79.3
Sample B Female 49.8
Sample C Male 59.6
Sample D Male 55.6
Periaqueductal gray
nTPM: 50.2
Samples: 3

Max nTPM: 58.5
Min nTPM: 46.1
Sample B Female 46.1
Sample C Male 58.5
Sample D Male 46.1
Substantia nigra
nTPM: 59.9
Samples: 4

Max nTPM: 79.8
Min nTPM: 45.0
Sample A Female 79.8
Sample B Female 45.0
Sample C Male 67.2
Sample D Male 47.4
Superior colliculi
nTPM: 60.0
Samples: 4

Max nTPM: 67.2
Min nTPM: 48.2
Sample A Female 67.2
Sample B Female 48.2
Sample C Male 67.0
Sample D Male 57.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 200.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 200.9
Samples: 4

Max nTPM: 205.7
Min nTPM: 192.8
Sample A Male 203.5
Sample B Male 205.7
Sample C Female 201.5
Sample D Female 192.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.4
68191552 Antisense, RP_041129_01_D07, Mouse strain C57BL/6J (56 days, male) 2.4

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