We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
NEDD8
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • METABOLIC
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • METABOLIC

  • NEDD8
BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:162.4 nTPM
HPA:162.4 nTPM
FANTOM5:171.2 Scaled Tags Per Million
Pig:96.1 nTPM
Allen mouse:5.0 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 162.4
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 152.7
2188 Female, age 91, both hemispheres 155.6
2301 Female, age 85, both hemispheres 153.3
2090 Male, age 80, both hemispheres 152.4
1984 Male, age 76, both hemispheres 149.6
Dorsal cochlear nucleus
nTPM: 155.4
2802 Male, age 74, right hemisphere 160.5
2187 Female, age 91, both hemispheres 158.6
2370 Male, age 61, both hemispheres 153.6
2378 Male, age 80, both hemispheres 152.4
2058 Male, age 76, both hemispheres 152.2
Dorsal tegmental nucleus
nTPM: 155.7
2083 Male, age 80, both hemispheres 160.2
2358 Male, age 61, both hemispheres 157.5
2326 Male, age 74, both hemispheres 155.0
1936 Male, age 76, left hemisphere 150.3
Dorsolateral tegmental area
nTPM: 156.5
2654 Male, age 80, both hemispheres 161.8
2751 Female, age 85, both hemispheres 156.7
2141 Male, age 76, both hemispheres 156.0
2337 Male, age 61, both hemispheres 155.6
2360 Male, age 74, both hemispheres 152.5
Kolliker-Fuse nucleus
nTPM: 157.0
2163 Male, age 80, both hemispheres 160.7
2793 Female, age 91, left hemisphere 156.5
2315 Male, age 76, right hemisphere 153.6
Lateral lemniscal nuclei
nTPM: 155.4
2169 Male, age 76, both hemispheres 165.3
2746 Female, age 85, left hemisphere 159.1
2453 Male, age 74, right hemisphere 155.1
2320 Female, age 91, left hemisphere 148.9
2036 Male, age 80, both hemispheres 148.6
Lateral parabrachial nucleus
nTPM: 158.2
2139 Female, age 85, right hemisphere 165.6
2790 Male, age 61, both hemispheres 157.4
2013 Male, age 80, both hemispheres 155.5
2792 Male, age 76, both hemispheres 154.4
Lateral vestibular nucleus
nTPM: 155.8
2184 Male, age 76, both hemispheres 156.6
2311 Male, age 80, both hemispheres 155.0
Locus coeruleus
nTPM: 162.4
2123 Female, age 91, both hemispheres 169.7
2720 Male, age 74, both hemispheres 166.8
2014 Male, age 55, unknown 165.9
2788 Male, age 74, unknown 161.4
2317 Female, age 72, unknown 158.0
1980 Male, age 76, both hemispheres 157.6
2162 Male, age 80, both hemispheres 157.5
Medial olivary nucleus
nTPM: 153.6
2851 Male, age 80, both hemispheres 154.8
2138 Female, age 91, both hemispheres 154.5
1943 Male, age 61, both hemispheres 153.4
1962 Male, age 76, both hemispheres 151.6
Medial parabrachial nucleus
nTPM: 157.8
2170 Female, age 91, both hemispheres 163.5
2854 Male, age 80, both hemispheres 162.9
2156 Male, age 61, both hemispheres 155.3
2786 Male, age 76, both hemispheres 154.8
2463 Female, age 85, right hemisphere 152.4
Medial periolivary nuclei
nTPM: 156.9
2063 Male, age 76, both hemispheres 163.7
2171 Female, age 85, both hemispheres 162.6
2791 Male, age 74, right hemisphere 157.7
2081 Male, age 80, both hemispheres 150.5
2458 Female, age 91, both hemispheres 149.9
Motor facial nucleus
nTPM: 159.3
2062 Male, age 76, both hemispheres 166.0
2365 Male, age 74, right hemisphere 162.0
2697 Female, age 85, both hemispheres 162.0
2795 Female, age 91, both hemispheres 156.2
2126 Male, age 61, both hemispheres 155.2
2327 Male, age 80, both hemispheres 154.2
Motor trigeminal nucleus
nTPM: 152.8
2079 Male, age 80, both hemispheres 154.5
2309 Male, age 76, both hemispheres 154.4
2335 Male, age 61, both hemispheres 153.6
2560 Male, age 74, both hemispheres 152.9
2321 Female, age 91, both hemispheres 148.7
Nuclei of the trapezoid body
nTPM: 160.4
2159 Male, age 61, both hemispheres 171.1
1983 Male, age 76, both hemispheres 166.3
2735 Female, age 85, both hemispheres 161.3
2166 Male, age 80, both hemispheres 155.1
2368 Female, age 91, both hemispheres 148.0
Paramedian reticular nucleus
nTPM: 159.2
2050 Female, age 85, both hemispheres 168.9
2313 Male, age 61, both hemispheres 158.7
2057 Male, age 80, both hemispheres 157.1
2052 Male, age 76, both hemispheres 152.1
Pontine nuclei
nTPM: 161.5
1863 Male, age 55, unknown 171.2
2787 Female, age 85, both hemispheres 170.1
2727 Male, age 61, right hemisphere 166.7
1968 Male, age 76, left hemisphere 162.2
2109 Female, age 72, unknown 161.5
2454 Male, age 74, left hemisphere 155.3
2319 Female, age 91, both hemispheres 153.9
2115 Male, age 80, left hemisphere 151.3
Pontine raphe nucleus
nTPM: 161.3
2122 Female, age 85, midline 162.7
2853 Male, age 76, midline 159.8
Posteroventral cochlear nucleus
nTPM: 154.6
2752 Female, age 85, both hemispheres 158.4
2070 Male, age 76, both hemispheres 155.5
2135 Female, age 91, both hemispheres 154.7
2341 Male, age 80, both hemispheres 153.1
2371 Male, age 61, both hemispheres 151.3
Principal sensory trigeminal nucleus
nTPM: 157.7
2158 Male, age 61, both hemispheres 167.3
2008 Male, age 80, left hemisphere 156.8
2324 Male, age 76, both hemispheres 155.1
2367 Female, age 91, left hemisphere 151.6
Reticular pontine nucleus, caudal
nTPM: 155.1
2092 Male, age 76, both hemispheres 161.0
2332 Male, age 80, right hemisphere 154.9
2559 Male, age 74, both hemispheres 154.4
2457 Female, age 91, both hemispheres 149.9
Reticular pontine nucleus, oral
nTPM: 157.1
2012 Female, age 85, both hemispheres 161.1
1939 Male, age 80, both hemispheres 159.6
2167 Male, age 76, both hemispheres 158.5
2366 Female, age 91, both hemispheres 155.2
2361 Male, age 74, both hemispheres 151.0
Reticulotegmental nucleus
nTPM: 156.5
2325 Male, age 76, both hemispheres 160.6
2322 Female, age 91, both hemispheres 157.5
2333 Male, age 80, both hemispheres 154.0
2452 Male, age 74, both hemispheres 153.9
Spinal trigeminal nucleus, oral
nTPM: 154.9
2164 Male, age 80, both hemispheres 157.7
2737 Female, age 85, both hemispheres 154.2
1978 Male, age 76, both hemispheres 152.7
Subcoeruleus area
nTPM: 157.7
1958 Male, age 80, both hemispheres 162.2
2323 Female, age 91, left hemisphere 161.7
2369 Female, age 85, left hemisphere 156.4
2089 Male, age 76, left hemisphere 155.7
2451 Male, age 74, both hemispheres 152.6
Superior olive
nTPM: 158.8
1875 Female, age 85, both hemispheres 168.7
2364 Male, age 74, right hemisphere 161.9
2020 Male, age 76, both hemispheres 158.2
2329 Male, age 80, right hemisphere 153.6
2561 Female, age 91, both hemispheres 151.6
Superior vestibular nucleus
nTPM: 158.1
2383 Male, age 74, both hemispheres 163.4
2015 Male, age 80, both hemispheres 157.8
2061 Male, age 76, both hemispheres 153.2
Ventral periolivary nuclei
nTPM: 160.5
2130 Female, age 85, both hemispheres 164.3
2165 Male, age 80, both hemispheres 160.9
2023 Male, age 76, both hemispheres 159.7
2794 Female, age 91, left hemisphere 157.1
Ventrolateral tegmental area, A5 NE cell group
nTPM: 156.5
2840 Female, age 85, both hemispheres 163.0
1959 Male, age 76, both hemispheres 160.2
2449 Male, age 74, both hemispheres 157.1
2359 Male, age 61, both hemispheres 156.5
2161 Male, age 80, both hemispheres 155.2
2456 Female, age 91, both hemispheres 146.8

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 171.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 171.2
FF:10165-103B3 76 years, female 171.3
FF:10182-103D2 60 years, female 171.1
Pons
Scaled Tags Per Million: 167.7
FF:10033-101E6 18-54 years, mixed 167.7

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 96.1
Pig sample Sample description nTPM
Pons
nTPM: 96.1
Samples: 4

Max nTPM: 108.3
Min nTPM: 74.6
Sample A Female 103.3
Sample B Female 74.6
Sample C Male 108.3
Sample D Male 98.2

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 5.0
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 5.0
393259 Antisense, RP_040809_01_B01, Mouse strain C57BL/6J (56 days, male) 5.0

Contact

  • NEWS ARTICLES
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.