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  • ATP5IF1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:96.8 nTPM
HPA:96.8 nTPM
GTEx:293.8 nTPM
FANTOM5:222.3 Scaled Tags Per Million
Pig:204.3 nTPM
Mouse:449.1 nTPM
Allen mouse:9.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 96.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 91.2
1870 Female, age 42, unknown 95.5
2219 Male, age 76, both hemispheres 94.6
2411 Female, age 72, unknown 93.6
1827 Male, age 72, unknown 93.0
2019 Male, age 18, unknown 90.7
1833 Male, age 53, unknown 90.3
2666 Male, age 74, left hemisphere 89.6
1830 Male, age 51, unknown 89.5
2828 Female, age 72, unknown 88.2
2586 Male, age 75, left hemisphere 87.5
Dorsal raphe nucleus
nTPM: 91.9
1828 Male, age 53, unknown 94.3
2047 Male, age 72, unknown 93.1
2750 Male, age 76, both hemispheres 92.6
2298 Female, age 72, unknown 92.2
2016 Female, age 72, unknown 87.3
Inferior colliculus
nTPM: 94.5
2849 Male, age 72, unknown 96.5
1890 Male, age 53, unknown 95.1
2097 Female, age 72, unknown 93.9
1848 Female, age 42, unknown 92.4
Median raphe nucleus
nTPM: 96.6
2220 Male, age 76, midline 96.6
Pedunculopontine tegmental nucleus
nTPM: 96.8
1921 Female, age 85, both hemispheres 97.5
2338 Male, age 61, both hemispheres 97.1
2334 Male, age 80, both hemispheres 95.9
Periaquaductal grey, anterior
nTPM: 92.4
2502 Female, age 75, unknown 93.3
1795 Male, age 51, unknown 92.8
1947 Male, age 18, unknown 91.0
Periaquaductal grey, dorsal
nTPM: 91.2
2850 Male, age 76, both hemispheres 93.4
1840 Male, age 53, unknown 93.0
1831 Male, age 72, unknown 89.7
2464 Female, age 72, unknown 88.8
Periaquaductal grey, lateral
nTPM: 90.8
2140 Male, age 76, both hemispheres 91.5
2272 Male, age 74, both hemispheres 91.3
2053 Male, age 18, unknown 89.8
Pretectal area
nTPM: 93.3
2007 Male, age 72, unknown 97.0
1816 Male, age 51, unknown 96.6
1944 Female, age 72, unknown 96.4
1817 Female, age 42, unknown 95.5
2667 Female, age 75, unknown 95.1
2224 Female, age 72, unknown 92.7
2825 Male, age 18, unknown 91.8
1815 Male, age 53, unknown 91.7
2407 Male, age 75, both hemispheres 91.6
2273 Male, age 74, both hemispheres 90.0
2316 Male, age 76, right hemisphere 88.1
Red nucleus
nTPM: 92.1
2725 Female, age 75, unknown 95.7
1821 Female, age 72, unknown 94.7
1954 Female, age 42, unknown 92.7
2785 Male, age 18, unknown 92.5
1865 Male, age 51, unknown 92.1
2227 Male, age 72, unknown 92.1
2588 Male, age 74, left hemisphere 92.1
2769 Male, age 72, unknown 91.5
2503 Female, age 72, unknown 90.9
2823 Male, age 76, right hemisphere 90.5
2584 Male, age 75, left hemisphere 90.2
1904 Male, age 53, unknown 90.0
Substantia nigra
nTPM: 93.6
1916 Female, age 42, unknown 98.9
1889 Female, age 72, unknown 98.5
2699 Male, age 18, unknown 96.7
1851 Male, age 51, unknown 95.2
1941 Male, age 53, unknown 94.6
2665 Male, age 74, both hemispheres 92.4
2409 Female, age 72, unknown 92.1
2241 Male, age 72, unknown 91.2
2590 Female, age 75, unknown 89.4
2583 Male, age 75, right hemisphere 87.0
Superior colliculus
nTPM: 91.1
1895 Male, age 76, right hemisphere 96.2
2587 Male, age 74, left hemisphere 94.0
1796 Male, age 53, unknown 92.9
2087 Female, age 72, unknown 92.4
2261 Male, age 18, unknown 91.5
1913 Female, age 42, unknown 89.7
1839 Male, age 51, unknown 89.1
2668 Female, age 75, unknown 89.1
2664 Male, age 75, both hemispheres 88.9
1995 Male, age 72, unknown 87.3
Ventral tegmental area
nTPM: 93.9
2218 Male, age 76, both hemispheres 97.1
2410 Female, age 72, unknown 95.8
1915 Female, age 42, unknown 94.9
2223 Female, age 72, unknown 93.8
1942 Male, age 51, unknown 92.0
2021 Male, age 53, unknown 89.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 293.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 293.8
Samples: 139

Max nTPM: 619.3
Min nTPM: 133.3
Std nTPM: 104.1
Median nTPM: 268.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 619.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 612.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 592.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 580.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 527.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 473.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 472.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 467.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 466.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 463.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 462.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 462.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 443.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 441.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 441.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 434.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 432.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 426.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 420.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 417.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 416.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 409.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 405.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 405.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 405.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 403.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 394.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 393.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 391.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 381.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 363.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 356.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 356.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 354.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 351.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 349.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 347.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 346.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 345.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 343.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 339.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 335.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 335.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 334.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 333.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 333.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 332.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 321.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 312.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 311.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 310.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 307.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 306.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 304.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 299.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 298.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 298.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 297.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 292.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 290.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 289.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 285.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 284.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 282.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 278.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 274.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 274.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 273.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 269.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 268.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 267.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 266.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 265.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 264.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 261.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 259.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 255.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 250.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 248.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 247.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 245.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 244.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 242.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 242.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 242.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 239.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 237.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 237.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 236.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 234.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 233.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 231.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 230.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 227.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 225.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 225.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 224.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 222.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 221.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 221.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 217.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 214.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 214.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 213.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 209.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 209.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 209.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 208.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 208.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 208.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 205.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 204.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 203.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 202.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 199.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 198.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 195.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 194.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 192.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 192.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 191.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 190.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 190.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 188.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 188.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 180.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 177.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 177.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 176.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 176.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 168.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 165.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 159.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 158.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 156.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 153.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 149.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 139.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 133.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 222.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 222.3
FF:10158-103A5 76 years, female 222.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 204.3
Pig sample Sample description nTPM
Midbrain
nTPM: 181.1
Samples: 4

Max nTPM: 198.4
Min nTPM: 162.2
Sample A Female 162.2
Sample B Female 176.7
Sample C Male 198.4
Sample D Male 187.0
Periaqueductal gray
nTPM: 135.1
Samples: 3

Max nTPM: 158.2
Min nTPM: 116.2
Sample B Female 130.8
Sample C Male 158.2
Sample D Male 116.2
Substantia nigra
nTPM: 195.1
Samples: 4

Max nTPM: 313.1
Min nTPM: 101.3
Sample A Female 313.1
Sample B Female 155.4
Sample C Male 210.6
Sample D Male 101.3
Superior colliculi
nTPM: 204.3
Samples: 4

Max nTPM: 251.4
Min nTPM: 157.6
Sample A Female 245.1
Sample B Female 163.2
Sample C Male 251.4
Sample D Male 157.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 449.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 449.1
Samples: 4

Max nTPM: 501.3
Min nTPM: 403.7
Sample A Male 501.3
Sample B Male 423.3
Sample C Female 403.7
Sample D Female 468.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 9.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.1
75774682 Antisense, RP_060530_01_D07, Mouse strain C57BL/6J (56 days, male) 10.9
67978746 Antisense, RP_040923_01_G06, Mouse strain C57BL/6J (56 days, male) 7.4

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