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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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101.508
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:431.3 nTPM
HPA:431.3 nTPM
FANTOM5:2760.9 Scaled Tags Per Million
Pig:425.9 nTPM
Allen mouse:16.3 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody HPA022275
Pons mean intensity 101.508
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 38.662
Parabrachial nucleus 37.626
Principle sensory trigeminal nucleus 30.113
Locus coeruleus 84.648
Pontine nucleus 36.012
Vestibular nucleus 38.523
Pontine reticular nucleus, oral 14.131
Lateral lemniscus 18.579
Superior paraolivary nucleus 11.077

PONS - HPA Brain RNA-seq
Max nTPM 431.3
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 143.0
2301 Female, age 85, both hemispheres 174.4
2188 Female, age 91, both hemispheres 168.0
1984 Male, age 76, both hemispheres 155.0
2090 Male, age 80, both hemispheres 74.6
Dorsal cochlear nucleus
nTPM: 132.4
2187 Female, age 91, both hemispheres 200.3
2058 Male, age 76, both hemispheres 161.7
2802 Male, age 74, right hemisphere 161.2
2370 Male, age 61, both hemispheres 83.9
2378 Male, age 80, both hemispheres 54.9
Dorsal tegmental nucleus
nTPM: 163.1
2083 Male, age 80, both hemispheres 200.6
2326 Male, age 74, both hemispheres 159.5
2358 Male, age 61, both hemispheres 154.7
1936 Male, age 76, left hemisphere 137.6
Dorsolateral tegmental area
nTPM: 127.4
2751 Female, age 85, both hemispheres 183.4
2654 Male, age 80, both hemispheres 175.5
2141 Male, age 76, both hemispheres 129.3
2360 Male, age 74, both hemispheres 95.2
2337 Male, age 61, both hemispheres 53.6
Kolliker-Fuse nucleus
nTPM: 213.4
2163 Male, age 80, both hemispheres 375.4
2793 Female, age 91, left hemisphere 168.9
2315 Male, age 76, right hemisphere 95.8
Lateral lemniscal nuclei
nTPM: 268.4
2169 Male, age 76, both hemispheres 391.2
2036 Male, age 80, both hemispheres 287.7
2453 Male, age 74, right hemisphere 264.0
2746 Female, age 85, left hemisphere 257.1
2320 Female, age 91, left hemisphere 142.1
Lateral parabrachial nucleus
nTPM: 174.3
2139 Female, age 85, right hemisphere 300.3
2790 Male, age 61, both hemispheres 199.9
2013 Male, age 80, both hemispheres 152.9
2792 Male, age 76, both hemispheres 44.1
Lateral vestibular nucleus
nTPM: 269.5
2184 Male, age 76, both hemispheres 398.4
2311 Male, age 80, both hemispheres 140.5
Locus coeruleus
nTPM: 431.3
2123 Female, age 91, both hemispheres 673.2
2720 Male, age 74, both hemispheres 472.4
2014 Male, age 55, unknown 460.3
1980 Male, age 76, both hemispheres 417.1
2788 Male, age 74, unknown 387.1
2317 Female, age 72, unknown 327.8
2162 Male, age 80, both hemispheres 281.2
Medial olivary nucleus
nTPM: 98.1
2138 Female, age 91, both hemispheres 117.5
2851 Male, age 80, both hemispheres 110.1
1962 Male, age 76, both hemispheres 98.6
1943 Male, age 61, both hemispheres 66.1
Medial parabrachial nucleus
nTPM: 204.4
2170 Female, age 91, both hemispheres 258.7
2156 Male, age 61, both hemispheres 242.5
2854 Male, age 80, both hemispheres 214.1
2463 Female, age 85, right hemisphere 161.0
2786 Male, age 76, both hemispheres 145.7
Medial periolivary nuclei
nTPM: 260.2
2171 Female, age 85, both hemispheres 464.2
2063 Male, age 76, both hemispheres 401.2
2791 Male, age 74, right hemisphere 215.3
2458 Female, age 91, both hemispheres 122.7
2081 Male, age 80, both hemispheres 97.3
Motor facial nucleus
nTPM: 262.1
2062 Male, age 76, both hemispheres 440.7
2365 Male, age 74, right hemisphere 292.3
2697 Female, age 85, both hemispheres 263.3
2327 Male, age 80, both hemispheres 235.3
2126 Male, age 61, both hemispheres 185.0
2795 Female, age 91, both hemispheres 155.7
Motor trigeminal nucleus
nTPM: 166.0
2079 Male, age 80, both hemispheres 246.3
2560 Male, age 74, both hemispheres 163.4
2309 Male, age 76, both hemispheres 145.8
2321 Female, age 91, both hemispheres 139.5
2335 Male, age 61, both hemispheres 134.9
Nuclei of the trapezoid body
nTPM: 339.5
2159 Male, age 61, both hemispheres 541.0
2735 Female, age 85, both hemispheres 409.3
1983 Male, age 76, both hemispheres 385.6
2166 Male, age 80, both hemispheres 211.7
2368 Female, age 91, both hemispheres 149.9
Paramedian reticular nucleus
nTPM: 279.0
2050 Female, age 85, both hemispheres 325.3
2057 Male, age 80, both hemispheres 320.2
2313 Male, age 61, both hemispheres 299.8
2052 Male, age 76, both hemispheres 170.6
Pontine nuclei
nTPM: 368.2
2727 Male, age 61, right hemisphere 687.5
1863 Male, age 55, unknown 579.6
2109 Female, age 72, unknown 446.2
2787 Female, age 85, both hemispheres 431.3
1968 Male, age 76, left hemisphere 339.5
2454 Male, age 74, left hemisphere 230.5
2319 Female, age 91, both hemispheres 122.2
2115 Male, age 80, left hemisphere 108.8
Pontine raphe nucleus
nTPM: 284.3
2122 Female, age 85, midline 349.0
2853 Male, age 76, midline 219.5
Posteroventral cochlear nucleus
nTPM: 139.1
2070 Male, age 76, both hemispheres 233.7
2752 Female, age 85, both hemispheres 223.9
2371 Male, age 61, both hemispheres 85.7
2341 Male, age 80, both hemispheres 80.8
2135 Female, age 91, both hemispheres 71.2
Principal sensory trigeminal nucleus
nTPM: 337.0
2158 Male, age 61, both hemispheres 592.4
2324 Male, age 76, both hemispheres 307.4
2008 Male, age 80, left hemisphere 294.9
2367 Female, age 91, left hemisphere 153.1
Reticular pontine nucleus, caudal
nTPM: 205.3
2332 Male, age 80, right hemisphere 276.7
2092 Male, age 76, both hemispheres 243.8
2559 Male, age 74, both hemispheres 161.5
2457 Female, age 91, both hemispheres 139.0
Reticular pontine nucleus, oral
nTPM: 215.7
2012 Female, age 85, both hemispheres 281.1
2361 Male, age 74, both hemispheres 266.4
1939 Male, age 80, both hemispheres 226.0
2167 Male, age 76, both hemispheres 172.4
2366 Female, age 91, both hemispheres 132.6
Reticulotegmental nucleus
nTPM: 221.2
2325 Male, age 76, both hemispheres 289.4
2452 Male, age 74, both hemispheres 237.8
2322 Female, age 91, both hemispheres 198.2
2333 Male, age 80, both hemispheres 159.5
Spinal trigeminal nucleus, oral
nTPM: 225.0
2164 Male, age 80, both hemispheres 313.0
2737 Female, age 85, both hemispheres 238.6
1978 Male, age 76, both hemispheres 123.5
Subcoeruleus area
nTPM: 199.7
2323 Female, age 91, left hemisphere 253.3
1958 Male, age 80, both hemispheres 249.2
2089 Male, age 76, left hemisphere 224.4
2451 Male, age 74, both hemispheres 151.4
2369 Female, age 85, left hemisphere 120.3
Superior olive
nTPM: 237.5
1875 Female, age 85, both hemispheres 376.7
2364 Male, age 74, right hemisphere 245.1
2020 Male, age 76, both hemispheres 218.6
2329 Male, age 80, right hemisphere 206.0
2561 Female, age 91, both hemispheres 141.0
Superior vestibular nucleus
nTPM: 167.2
2015 Male, age 80, both hemispheres 207.8
2383 Male, age 74, both hemispheres 152.5
2061 Male, age 76, both hemispheres 141.5
Ventral periolivary nuclei
nTPM: 272.8
2130 Female, age 85, both hemispheres 395.8
2165 Male, age 80, both hemispheres 345.2
2023 Male, age 76, both hemispheres 194.7
2794 Female, age 91, left hemisphere 155.5
Ventrolateral tegmental area, A5 NE cell group
nTPM: 216.4
2449 Male, age 74, both hemispheres 298.1
2840 Female, age 85, both hemispheres 273.0
1959 Male, age 76, both hemispheres 242.6
2359 Male, age 61, both hemispheres 202.9
2161 Male, age 80, both hemispheres 194.8
2456 Female, age 91, both hemispheres 87.0

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 2760.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 1268.0
FF:10182-103D2 60 years, female 1710.2
FF:10165-103B3 76 years, female 825.9
Pons
Scaled Tags Per Million: 2760.9
FF:10033-101E6 18-54 years, mixed 2760.9

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 425.9
Pig sample Sample description nTPM
Pons
nTPM: 425.9
Samples: 4

Max nTPM: 528.5
Min nTPM: 342.2
Sample A Female 528.5
Sample B Female 342.2
Sample C Male 413.5
Sample D Male 419.3

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 16.3
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 16.3
71570737 Antisense, RP_050505_01_H06, Mouse strain C57BL/6J (56 days, male) 17.3
73834355 Antisense, RP_051212_03_G08, Mouse strain C57BL/6J (56 days, male) 15.4

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.