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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:156.2 nTPM
HPA:156.2 nTPM
GTEx:166.3 nTPM
FANTOM5:77.4 Scaled Tags Per Million
Pig:132.1 nTPM
Mouse:104.2 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 156.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 145.1
1870 Female, age 42, unknown 150.9
2019 Male, age 18, unknown 149.9
2411 Female, age 72, unknown 149.8
1827 Male, age 72, unknown 148.1
2828 Female, age 72, unknown 146.5
2219 Male, age 76, both hemispheres 142.6
1833 Male, age 53, unknown 142.4
1830 Male, age 51, unknown 142.3
2666 Male, age 74, left hemisphere 140.5
2586 Male, age 75, left hemisphere 137.9
Dorsal raphe nucleus
nTPM: 149.4
2298 Female, age 72, unknown 159.3
2750 Male, age 76, both hemispheres 148.5
2047 Male, age 72, unknown 148.2
1828 Male, age 53, unknown 146.9
2016 Female, age 72, unknown 144.3
Inferior colliculus
nTPM: 143.7
2097 Female, age 72, unknown 150.9
1890 Male, age 53, unknown 142.8
1848 Female, age 42, unknown 142.6
2849 Male, age 72, unknown 138.5
Median raphe nucleus
nTPM: 150.4
2220 Male, age 76, midline 150.4
Pedunculopontine tegmental nucleus
nTPM: 154.7
2338 Male, age 61, both hemispheres 158.3
2334 Male, age 80, both hemispheres 154.5
1921 Female, age 85, both hemispheres 151.4
Periaquaductal grey, anterior
nTPM: 151.2
2502 Female, age 75, unknown 152.8
1947 Male, age 18, unknown 151.4
1795 Male, age 51, unknown 149.3
Periaquaductal grey, dorsal
nTPM: 144.7
2850 Male, age 76, both hemispheres 146.6
1840 Male, age 53, unknown 145.1
1831 Male, age 72, unknown 143.8
2464 Female, age 72, unknown 143.4
Periaquaductal grey, lateral
nTPM: 147.0
2272 Male, age 74, both hemispheres 150.1
2053 Male, age 18, unknown 149.1
2140 Male, age 76, both hemispheres 141.8
Pretectal area
nTPM: 150.4
1816 Male, age 51, unknown 160.5
1944 Female, age 72, unknown 153.9
2007 Male, age 72, unknown 153.9
1817 Female, age 42, unknown 153.5
2273 Male, age 74, both hemispheres 151.9
2224 Female, age 72, unknown 151.8
1815 Male, age 53, unknown 151.7
2667 Female, age 75, unknown 145.0
2825 Male, age 18, unknown 144.5
2407 Male, age 75, both hemispheres 144.1
2316 Male, age 76, right hemisphere 143.8
Red nucleus
nTPM: 146.5
1821 Female, age 72, unknown 155.1
2725 Female, age 75, unknown 154.2
2823 Male, age 76, right hemisphere 148.6
1954 Female, age 42, unknown 147.9
1865 Male, age 51, unknown 146.4
2503 Female, age 72, unknown 146.4
1904 Male, age 53, unknown 145.6
2227 Male, age 72, unknown 145.5
2769 Male, age 72, unknown 143.6
2785 Male, age 18, unknown 142.6
2584 Male, age 75, left hemisphere 141.9
2588 Male, age 74, left hemisphere 139.8
Substantia nigra
nTPM: 156.2
1941 Male, age 53, unknown 170.4
2241 Male, age 72, unknown 165.8
1916 Female, age 42, unknown 163.6
1851 Male, age 51, unknown 162.3
1889 Female, age 72, unknown 156.2
2409 Female, age 72, unknown 152.5
2665 Male, age 74, both hemispheres 150.3
2699 Male, age 18, unknown 149.5
2590 Female, age 75, unknown 148.1
2583 Male, age 75, right hemisphere 143.7
Superior colliculus
nTPM: 147.3
2261 Male, age 18, unknown 154.5
2587 Male, age 74, left hemisphere 150.6
2668 Female, age 75, unknown 149.5
2087 Female, age 72, unknown 148.8
1895 Male, age 76, right hemisphere 148.3
1913 Female, age 42, unknown 146.7
1796 Male, age 53, unknown 146.5
1995 Male, age 72, unknown 144.8
2664 Male, age 75, both hemispheres 142.9
1839 Male, age 51, unknown 140.4
Ventral tegmental area
nTPM: 151.9
1915 Female, age 42, unknown 156.5
2410 Female, age 72, unknown 156.4
2218 Male, age 76, both hemispheres 152.0
1942 Male, age 51, unknown 150.2
2223 Female, age 72, unknown 150.2
2021 Male, age 53, unknown 146.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 166.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 166.3
Samples: 139

Max nTPM: 400.2
Min nTPM: 103.6
Std nTPM: 43.2
Median nTPM: 157.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 400.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 305.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 288.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 285.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 272.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 259.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 255.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 242.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 241.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 232.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 230.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 221.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 219.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 213.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 210.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 210.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 208.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 206.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 206.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 205.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 204.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 203.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 202.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 199.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 197.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 197.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 195.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 194.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 194.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 189.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 186.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 185.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 183.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 183.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 183.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 182.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 181.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 179.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 179.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 178.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 177.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 177.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 175.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 174.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 173.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 172.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 172.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 172.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 171.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 170.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 169.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 169.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 169.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 167.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 167.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 166.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 165.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 165.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 164.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 164.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 163.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 162.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 161.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 160.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 159.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 159.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 158.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 158.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 158.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 157.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 155.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 155.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 155.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 155.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 155.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 154.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 154.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 153.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 153.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 152.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 152.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 151.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 149.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 148.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 148.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 147.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 147.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 146.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 146.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 145.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 145.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 145.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 144.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 144.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 144.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 143.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 143.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 142.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 141.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 141.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 140.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 140.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 140.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 139.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 139.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 136.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 136.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 134.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 133.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 133.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 132.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 132.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 131.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 130.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 129.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 129.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 129.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 129.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 127.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 127.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 127.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 127.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 126.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 126.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 124.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 123.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 123.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 123.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 122.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 122.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 119.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 117.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 114.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 112.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 111.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 108.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 107.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 104.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 103.6
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 77.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 77.4
FF:10158-103A5 76 years, female 77.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 132.1
Pig sample Sample description nTPM
Midbrain
nTPM: 113.3
Samples: 4

Max nTPM: 126.2
Min nTPM: 99.7
Sample A Female 121.3
Sample B Female 106.1
Sample C Male 126.2
Sample D Male 99.7
Periaqueductal gray
nTPM: 84.6
Samples: 3

Max nTPM: 91.7
Min nTPM: 79.7
Sample B Female 82.4
Sample C Male 91.7
Sample D Male 79.7
Substantia nigra
nTPM: 116.6
Samples: 4

Max nTPM: 171.2
Min nTPM: 75.6
Sample A Female 171.2
Sample B Female 113.3
Sample C Male 106.3
Sample D Male 75.6
Superior colliculi
nTPM: 132.1
Samples: 4

Max nTPM: 147.4
Min nTPM: 93.8
Sample A Female 147.4
Sample B Female 141.0
Sample C Male 146.2
Sample D Male 93.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 104.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 104.2
Samples: 4

Max nTPM: 115.6
Min nTPM: 92.8
Sample A Male 115.6
Sample B Male 100.4
Sample C Female 92.8
Sample D Female 108.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
73573289 Antisense, RP_051121_03_F10, Mouse strain C57BL/6J (56 days, male) 0.7

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