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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:34.8 nTPM
HPA:34.8 nTPM
GTEx:58.5 nTPM
FANTOM5:46.1 Scaled Tags Per Million
Pig:69.1 nTPM
Mouse:151.8 nTPM
Allen mouse:1.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 34.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 32.6
2586 Male, age 75, left hemisphere 34.7
2019 Male, age 18, unknown 33.7
1870 Female, age 42, unknown 33.6
2411 Female, age 72, unknown 33.3
1827 Male, age 72, unknown 33.2
1833 Male, age 53, unknown 32.9
1830 Male, age 51, unknown 32.3
2828 Female, age 72, unknown 31.7
2219 Male, age 76, both hemispheres 30.4
2666 Male, age 74, left hemisphere 30.2
Dorsal raphe nucleus
nTPM: 31.7
2750 Male, age 76, both hemispheres 33.3
1828 Male, age 53, unknown 32.4
2298 Female, age 72, unknown 31.7
2016 Female, age 72, unknown 30.7
2047 Male, age 72, unknown 30.6
Inferior colliculus
nTPM: 31.9
2097 Female, age 72, unknown 32.7
1848 Female, age 42, unknown 32.6
1890 Male, age 53, unknown 31.9
2849 Male, age 72, unknown 30.5
Median raphe nucleus
nTPM: 31.5
2220 Male, age 76, midline 31.5
Pedunculopontine tegmental nucleus
nTPM: 32.5
2334 Male, age 80, both hemispheres 33.2
2338 Male, age 61, both hemispheres 32.4
1921 Female, age 85, both hemispheres 31.9
Periaquaductal grey, anterior
nTPM: 32.9
1947 Male, age 18, unknown 33.7
2502 Female, age 75, unknown 33.3
1795 Male, age 51, unknown 31.6
Periaquaductal grey, dorsal
nTPM: 30.5
1831 Male, age 72, unknown 31.7
2850 Male, age 76, both hemispheres 30.9
1840 Male, age 53, unknown 30.3
2464 Female, age 72, unknown 29.0
Periaquaductal grey, lateral
nTPM: 30.5
2272 Male, age 74, both hemispheres 31.7
2053 Male, age 18, unknown 30.5
2140 Male, age 76, both hemispheres 29.5
Pretectal area
nTPM: 32.7
2007 Male, age 72, unknown 35.6
1816 Male, age 51, unknown 34.8
1815 Male, age 53, unknown 34.3
1817 Female, age 42, unknown 33.9
2825 Male, age 18, unknown 32.9
1944 Female, age 72, unknown 32.7
2667 Female, age 75, unknown 32.3
2273 Male, age 74, both hemispheres 32.1
2407 Male, age 75, both hemispheres 31.2
2224 Female, age 72, unknown 30.1
2316 Male, age 76, right hemisphere 29.5
Red nucleus
nTPM: 34.8
1821 Female, age 72, unknown 36.1
2769 Male, age 72, unknown 36.0
1954 Female, age 42, unknown 35.4
2227 Male, age 72, unknown 35.4
2785 Male, age 18, unknown 35.4
2503 Female, age 72, unknown 35.0
2584 Male, age 75, left hemisphere 34.5
2725 Female, age 75, unknown 34.4
1865 Male, age 51, unknown 34.3
1904 Male, age 53, unknown 34.3
2823 Male, age 76, right hemisphere 34.0
2588 Male, age 74, left hemisphere 33.2
Substantia nigra
nTPM: 33.6
2665 Male, age 74, both hemispheres 36.0
1916 Female, age 42, unknown 35.2
1889 Female, age 72, unknown 35.1
1851 Male, age 51, unknown 34.6
2409 Female, age 72, unknown 33.7
1941 Male, age 53, unknown 33.6
2583 Male, age 75, right hemisphere 33.5
2699 Male, age 18, unknown 32.2
2590 Female, age 75, unknown 32.0
2241 Male, age 72, unknown 30.0
Superior colliculus
nTPM: 32.6
2668 Female, age 75, unknown 34.2
1913 Female, age 42, unknown 33.8
2087 Female, age 72, unknown 33.4
1895 Male, age 76, right hemisphere 33.0
1995 Male, age 72, unknown 32.9
1839 Male, age 51, unknown 32.3
2587 Male, age 74, left hemisphere 32.1
2664 Male, age 75, both hemispheres 31.8
1796 Male, age 53, unknown 31.6
2261 Male, age 18, unknown 31.1
Ventral tegmental area
nTPM: 32.2
2223 Female, age 72, unknown 33.6
2410 Female, age 72, unknown 33.3
1915 Female, age 42, unknown 33.2
1942 Male, age 51, unknown 31.3
2218 Male, age 76, both hemispheres 31.0
2021 Male, age 53, unknown 30.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 58.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 58.5
Samples: 139

Max nTPM: 95.6
Min nTPM: 24.9
Std nTPM: 12.5
Median nTPM: 57.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 95.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 92.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 89.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 89.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 87.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 87.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 85.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 84.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 82.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 82.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 81.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 77.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 76.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 76.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 74.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 73.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 72.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 70.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 69.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 69.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 69.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 69.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 68.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 68.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 68.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 68.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 67.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 67.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 66.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 65.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 65.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 65.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 64.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 64.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 64.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 64.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 63.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 63.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 63.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 63.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 63.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 62.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 62.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 62.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 62.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 62.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 62.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 61.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 61.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 61.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 61.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 61.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 60.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 60.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 60.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 60.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 60.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 59.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 59.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 59.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 58.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 58.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 58.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 58.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 58.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 58.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 58.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 57.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 57.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 57.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 57.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 56.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 56.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 56.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 56.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 56.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 56.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 55.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 55.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 55.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 55.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 55.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 54.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 54.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 54.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 54.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 54.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 53.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 53.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 53.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 53.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 53.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 53.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 52.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 52.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 52.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 52.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 52.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 51.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 51.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 51.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 50.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 50.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 50.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 49.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 49.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 49.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 49.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 49.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 49.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 49.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 49.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 48.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 48.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 48.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 48.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 47.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 47.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 47.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 45.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 45.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 45.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 45.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 45.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 44.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 44.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 43.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 43.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 42.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 42.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 41.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 40.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 39.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 38.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 37.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 36.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 35.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 32.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 24.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 46.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 46.1
FF:10158-103A5 76 years, female 46.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 69.1
Pig sample Sample description nTPM
Midbrain
nTPM: 69.1
Samples: 4

Max nTPM: 105.9
Min nTPM: 53.4
Sample A Female 105.9
Sample B Female 62.3
Sample C Male 54.9
Sample D Male 53.4
Periaqueductal gray
nTPM: 49.6
Samples: 3

Max nTPM: 54.4
Min nTPM: 46.0
Sample B Female 48.5
Sample C Male 54.4
Sample D Male 46.0
Substantia nigra
nTPM: 65.2
Samples: 4

Max nTPM: 92.6
Min nTPM: 52.2
Sample A Female 92.6
Sample B Female 53.4
Sample C Male 62.7
Sample D Male 52.2
Superior colliculi
nTPM: 64.5
Samples: 4

Max nTPM: 85.8
Min nTPM: 48.8
Sample A Female 85.8
Sample B Female 48.8
Sample C Male 60.2
Sample D Male 63.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 151.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 151.8
Samples: 4

Max nTPM: 164.6
Min nTPM: 140.5
Sample A Male 164.6
Sample B Male 141.0
Sample C Female 140.5
Sample D Female 161.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.0
678683 Antisense, RP_040914_02_D02, Mouse strain C57BL/6J (56 days, male) 1.0

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