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C7orf50
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:66.2 nTPM
HPA:66.2 nTPM
GTEx:93.2 nTPM
FANTOM5:35.6 Scaled Tags Per Million
Pig:15.6 nTPM
Mouse:3.1 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 66.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 65.4
2586 Male, age 75, left hemisphere 87.3
2019 Male, age 18, unknown 66.7
2828 Female, age 72, unknown 66.4
1827 Male, age 72, unknown 65.6
1870 Female, age 42, unknown 63.8
2411 Female, age 72, unknown 62.5
1830 Male, age 51, unknown 61.9
1833 Male, age 53, unknown 61.7
2666 Male, age 74, left hemisphere 60.6
2219 Male, age 76, both hemispheres 57.7
Dorsal raphe nucleus
nTPM: 60.9
1828 Male, age 53, unknown 61.9
2016 Female, age 72, unknown 61.8
2047 Male, age 72, unknown 61.1
2298 Female, age 72, unknown 60.0
2750 Male, age 76, both hemispheres 59.5
Inferior colliculus
nTPM: 63.9
2849 Male, age 72, unknown 67.8
1848 Female, age 42, unknown 64.5
1890 Male, age 53, unknown 64.3
2097 Female, age 72, unknown 59.1
Median raphe nucleus
nTPM: 60.2
2220 Male, age 76, midline 60.2
Pedunculopontine tegmental nucleus
nTPM: 61.9
2338 Male, age 61, both hemispheres 64.6
2334 Male, age 80, both hemispheres 61.1
1921 Female, age 85, both hemispheres 59.9
Periaquaductal grey, anterior
nTPM: 65.3
2502 Female, age 75, unknown 68.6
1795 Male, age 51, unknown 66.6
1947 Male, age 18, unknown 60.9
Periaquaductal grey, dorsal
nTPM: 64.9
1840 Male, age 53, unknown 68.6
1831 Male, age 72, unknown 65.4
2464 Female, age 72, unknown 63.0
2850 Male, age 76, both hemispheres 62.7
Periaquaductal grey, lateral
nTPM: 61.2
2140 Male, age 76, both hemispheres 64.0
2053 Male, age 18, unknown 62.9
2272 Male, age 74, both hemispheres 56.7
Pretectal area
nTPM: 63.7
2007 Male, age 72, unknown 69.8
1816 Male, age 51, unknown 68.2
2407 Male, age 75, both hemispheres 65.9
1817 Female, age 42, unknown 65.5
2825 Male, age 18, unknown 64.3
2316 Male, age 76, right hemisphere 63.8
1815 Male, age 53, unknown 63.4
1944 Female, age 72, unknown 63.1
2667 Female, age 75, unknown 59.5
2224 Female, age 72, unknown 58.8
2273 Male, age 74, both hemispheres 58.6
Red nucleus
nTPM: 65.7
2584 Male, age 75, left hemisphere 72.5
2588 Male, age 74, left hemisphere 69.3
2503 Female, age 72, unknown 66.5
2769 Male, age 72, unknown 66.1
2785 Male, age 18, unknown 66.1
2227 Male, age 72, unknown 66.0
1904 Male, age 53, unknown 65.1
2823 Male, age 76, right hemisphere 64.5
1954 Female, age 42, unknown 64.2
1865 Male, age 51, unknown 62.9
2725 Female, age 75, unknown 62.9
1821 Female, age 72, unknown 62.1
Substantia nigra
nTPM: 62.3
2583 Male, age 75, right hemisphere 69.9
2590 Female, age 75, unknown 67.2
2665 Male, age 74, both hemispheres 66.3
1889 Female, age 72, unknown 62.7
2699 Male, age 18, unknown 61.1
1851 Male, age 51, unknown 60.6
1916 Female, age 42, unknown 60.6
2409 Female, age 72, unknown 60.6
1941 Male, age 53, unknown 60.1
2241 Male, age 72, unknown 54.1
Superior colliculus
nTPM: 66.2
2664 Male, age 75, both hemispheres 85.8
1796 Male, age 53, unknown 66.9
1839 Male, age 51, unknown 66.3
2261 Male, age 18, unknown 65.6
2668 Female, age 75, unknown 64.3
2087 Female, age 72, unknown 64.0
1995 Male, age 72, unknown 63.4
1913 Female, age 42, unknown 62.6
1895 Male, age 76, right hemisphere 61.5
2587 Male, age 74, left hemisphere 61.2
Ventral tegmental area
nTPM: 61.4
1915 Female, age 42, unknown 64.7
2223 Female, age 72, unknown 62.3
1942 Male, age 51, unknown 61.9
2021 Male, age 53, unknown 60.6
2410 Female, age 72, unknown 60.3
2218 Male, age 76, both hemispheres 58.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 93.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 93.2
Samples: 139

Max nTPM: 313.2
Min nTPM: 33.5
Std nTPM: 41.8
Median nTPM: 84.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 313.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 254.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 210.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 203.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 191.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 182.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 182.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 173.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 162.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 162.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 155.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 150.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 145.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 144.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 142.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 135.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 133.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 132.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 132.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 131.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 127.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 127.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 126.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 124.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 120.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 119.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 116.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 115.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 115.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 115.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 114.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 114.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 112.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 111.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 110.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 109.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 109.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 109.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 107.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 103.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 101.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 101.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 100.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 98.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 97.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 96.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 95.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 93.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 93.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 93.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 93.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 93.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 92.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 92.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 92.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 90.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 89.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 89.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 88.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 88.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 88.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 87.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 87.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 86.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 86.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 86.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 85.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 84.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 84.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 84.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 83.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 81.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 81.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 80.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 80.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 79.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 79.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 79.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 79.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 78.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 78.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 77.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 76.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 75.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 75.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 75.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 75.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 74.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 74.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 73.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 73.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 73.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 73.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 73.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 73.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 71.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 70.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 70.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 70.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 69.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 68.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 67.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 67.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 67.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 67.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 66.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 66.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 65.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 65.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 65.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 63.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 62.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 61.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 60.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 58.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 58.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 58.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 57.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 55.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 55.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 55.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 55.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 55.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 54.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 54.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 53.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 52.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 52.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 52.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 49.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 49.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 46.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 46.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 44.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 42.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 41.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 40.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 40.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 33.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 35.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 35.6
FF:10158-103A5 76 years, female 35.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 15.6
Pig sample Sample description nTPM
Midbrain
nTPM: 14.7
Samples: 4

Max nTPM: 17.7
Min nTPM: 11.4
Sample A Female 17.7
Sample B Female 15.2
Sample C Male 14.3
Sample D Male 11.4
Periaqueductal gray
nTPM: 12.2
Samples: 3

Max nTPM: 15.1
Min nTPM: 9.6
Sample B Female 11.8
Sample C Male 15.1
Sample D Male 9.6
Substantia nigra
nTPM: 14.4
Samples: 4

Max nTPM: 20.2
Min nTPM: 9.4
Sample A Female 20.2
Sample B Female 14.7
Sample C Male 13.3
Sample D Male 9.4
Superior colliculi
nTPM: 15.6
Samples: 4

Max nTPM: 18.8
Min nTPM: 12.2
Sample A Female 18.8
Sample B Female 16.0
Sample C Male 15.2
Sample D Male 12.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 3.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 3.2
Samples: 4

Max nTPM: 4.3
Min nTPM: 2.3
Sample A Male 4.3
Sample B Male 3.2
Sample C Female 2.3
Sample D Female 2.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
71656695 Antisense, RP_050927_04_B03, Mouse strain C57BL/6J (56 days, male) 0.0

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