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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:36.3 nTPM
HPA:36.3 nTPM
GTEx:27.1 nTPM
FANTOM5:109.0 Scaled Tags Per Million
Pig:24.9 nTPM
Mouse:29.4 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 36.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 29.4
1830 Male, age 51, unknown 38.3
1833 Male, age 53, unknown 38.3
1870 Female, age 42, unknown 35.4
2411 Female, age 72, unknown 35.1
2219 Male, age 76, both hemispheres 31.2
2019 Male, age 18, unknown 28.6
2828 Female, age 72, unknown 26.5
1827 Male, age 72, unknown 22.9
2586 Male, age 75, left hemisphere 19.7
2666 Male, age 74, left hemisphere 18.4
Dorsal raphe nucleus
nTPM: 22.0
2750 Male, age 76, both hemispheres 38.1
2016 Female, age 72, unknown 23.1
1828 Male, age 53, unknown 19.3
2047 Male, age 72, unknown 15.2
2298 Female, age 72, unknown 14.0
Inferior colliculus
nTPM: 22.5
2849 Male, age 72, unknown 24.5
1848 Female, age 42, unknown 24.2
1890 Male, age 53, unknown 22.4
2097 Female, age 72, unknown 19.0
Median raphe nucleus
nTPM: 25.2
2220 Male, age 76, midline 25.2
Pedunculopontine tegmental nucleus
nTPM: 25.7
2334 Male, age 80, both hemispheres 29.6
1921 Female, age 85, both hemispheres 27.4
2338 Male, age 61, both hemispheres 20.2
Periaquaductal grey, anterior
nTPM: 16.1
2502 Female, age 75, unknown 19.3
1947 Male, age 18, unknown 17.1
1795 Male, age 51, unknown 11.9
Periaquaductal grey, dorsal
nTPM: 16.6
2464 Female, age 72, unknown 23.2
1831 Male, age 72, unknown 15.7
1840 Male, age 53, unknown 14.6
2850 Male, age 76, both hemispheres 13.0
Periaquaductal grey, lateral
nTPM: 17.5
2272 Male, age 74, both hemispheres 21.2
2053 Male, age 18, unknown 19.3
2140 Male, age 76, both hemispheres 12.0
Pretectal area
nTPM: 20.6
2667 Female, age 75, unknown 28.0
2316 Male, age 76, right hemisphere 26.0
1815 Male, age 53, unknown 24.7
2407 Male, age 75, both hemispheres 22.4
2825 Male, age 18, unknown 20.7
2273 Male, age 74, both hemispheres 20.6
1817 Female, age 42, unknown 19.9
2224 Female, age 72, unknown 19.7
2007 Male, age 72, unknown 19.2
1944 Female, age 72, unknown 13.7
1816 Male, age 51, unknown 11.8
Red nucleus
nTPM: 36.3
1865 Male, age 51, unknown 48.3
1904 Male, age 53, unknown 43.5
2503 Female, age 72, unknown 39.7
1821 Female, age 72, unknown 39.3
1954 Female, age 42, unknown 39.1
2769 Male, age 72, unknown 38.4
2823 Male, age 76, right hemisphere 36.2
2227 Male, age 72, unknown 34.9
2588 Male, age 74, left hemisphere 34.8
2785 Male, age 18, unknown 34.2
2584 Male, age 75, left hemisphere 27.3
2725 Female, age 75, unknown 20.0
Substantia nigra
nTPM: 27.1
2409 Female, age 72, unknown 32.8
2699 Male, age 18, unknown 32.1
2590 Female, age 75, unknown 31.5
2241 Male, age 72, unknown 29.7
1851 Male, age 51, unknown 28.8
2583 Male, age 75, right hemisphere 28.2
1916 Female, age 42, unknown 25.5
1889 Female, age 72, unknown 24.4
1941 Male, age 53, unknown 21.1
2665 Male, age 74, both hemispheres 17.0
Superior colliculus
nTPM: 23.4
1913 Female, age 42, unknown 33.6
1895 Male, age 76, right hemisphere 33.4
1995 Male, age 72, unknown 31.7
1839 Male, age 51, unknown 26.0
2587 Male, age 74, left hemisphere 24.3
2668 Female, age 75, unknown 20.8
1796 Male, age 53, unknown 18.3
2261 Male, age 18, unknown 15.9
2664 Male, age 75, both hemispheres 15.9
2087 Female, age 72, unknown 14.1
Ventral tegmental area
nTPM: 28.7
2223 Female, age 72, unknown 36.4
2410 Female, age 72, unknown 31.7
2218 Male, age 76, both hemispheres 30.2
2021 Male, age 53, unknown 25.4
1942 Male, age 51, unknown 24.5
1915 Female, age 42, unknown 23.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 27.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 27.1
Samples: 139

Max nTPM: 69.5
Min nTPM: 13.2
Std nTPM: 9.1
Median nTPM: 25.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 69.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 58.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 52.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 52.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 50.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 45.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 45.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 44.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 43.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 42.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 41.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 40.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 39.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 39.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 38.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 37.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 36.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 36.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 35.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 35.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 35.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 34.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 34.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 34.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 33.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 33.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 32.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 32.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 32.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 31.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 31.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 31.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 31.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 31.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 30.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 30.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 30.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 30.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 30.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 29.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 29.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 29.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 29.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 29.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 29.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 29.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 28.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 28.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 28.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 28.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 28.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 28.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 28.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 28.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 28.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 27.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 27.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 27.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 26.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 26.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 26.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 26.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 26.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 26.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 26.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 26.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 26.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 25.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 25.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 25.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 25.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 25.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 24.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 24.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 24.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 24.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 24.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 24.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 24.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 24.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 24.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 24.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 24.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 24.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 23.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 23.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 23.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 23.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 23.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 22.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 22.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 22.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 22.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 21.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 21.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 21.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 21.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 21.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 21.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 21.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 21.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 21.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 21.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 20.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 20.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 20.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 20.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 20.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 20.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 20.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 20.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 20.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 19.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 19.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 19.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 19.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 19.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 18.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 18.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 18.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 18.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 18.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 17.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 17.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 17.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 17.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 16.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 16.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 15.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 15.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 15.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 15.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 15.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 15.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 15.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 15.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 14.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 13.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 13.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 109.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 109.0
FF:10158-103A5 76 years, female 109.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 24.9
Pig sample Sample description nTPM
Midbrain
nTPM: 23.1
Samples: 4

Max nTPM: 25.6
Min nTPM: 21.3
Sample A Female 21.8
Sample B Female 21.3
Sample C Male 23.6
Sample D Male 25.6
Periaqueductal gray
nTPM: 17.5
Samples: 3

Max nTPM: 19.0
Min nTPM: 16.1
Sample B Female 19.0
Sample C Male 17.3
Sample D Male 16.1
Substantia nigra
nTPM: 25.0
Samples: 4

Max nTPM: 26.2
Min nTPM: 22.0
Sample A Female 22.0
Sample B Female 26.0
Sample C Male 25.6
Sample D Male 26.2
Superior colliculi
nTPM: 21.5
Samples: 4

Max nTPM: 25.6
Min nTPM: 16.6
Sample A Female 21.1
Sample B Female 16.6
Sample C Male 22.5
Sample D Male 25.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 29.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 29.4
Samples: 4

Max nTPM: 32.0
Min nTPM: 27.4
Sample A Male 28.6
Sample B Male 32.0
Sample C Female 29.7
Sample D Female 27.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
72081756 Antisense, RP_051019_01_A07, Mouse strain C57BL/6J (56 days, male) 0.1

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