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ATP5F1A
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  • ATP5F1A
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:237.8 nTPM
HPA:237.8 nTPM
GTEx:319.5 nTPM
FANTOM5:139.2 Scaled Tags Per Million
Pig:152.4 nTPM
Mouse:798.7 nTPM
Allen mouse:12.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 237.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 192.2
2219 Male, age 76, both hemispheres 218.8
1827 Male, age 72, unknown 203.1
2411 Female, age 72, unknown 203.0
2019 Male, age 18, unknown 202.9
2828 Female, age 72, unknown 190.7
1833 Male, age 53, unknown 189.1
1870 Female, age 42, unknown 188.9
1830 Male, age 51, unknown 177.1
2666 Male, age 74, left hemisphere 175.7
2586 Male, age 75, left hemisphere 172.7
Dorsal raphe nucleus
nTPM: 205.2
2298 Female, age 72, unknown 226.0
1828 Male, age 53, unknown 221.0
2047 Male, age 72, unknown 202.3
2750 Male, age 76, both hemispheres 190.7
2016 Female, age 72, unknown 186.2
Inferior colliculus
nTPM: 208.7
2097 Female, age 72, unknown 228.0
1890 Male, age 53, unknown 212.0
1848 Female, age 42, unknown 206.3
2849 Male, age 72, unknown 188.7
Median raphe nucleus
nTPM: 192.3
2220 Male, age 76, midline 192.3
Pedunculopontine tegmental nucleus
nTPM: 200.8
1921 Female, age 85, both hemispheres 212.5
2334 Male, age 80, both hemispheres 205.8
2338 Male, age 61, both hemispheres 184.1
Periaquaductal grey, anterior
nTPM: 193.0
1947 Male, age 18, unknown 204.2
1795 Male, age 51, unknown 190.1
2502 Female, age 75, unknown 184.6
Periaquaductal grey, dorsal
nTPM: 186.1
1840 Male, age 53, unknown 196.4
2464 Female, age 72, unknown 183.8
1831 Male, age 72, unknown 183.4
2850 Male, age 76, both hemispheres 180.9
Periaquaductal grey, lateral
nTPM: 188.3
2272 Male, age 74, both hemispheres 208.3
2053 Male, age 18, unknown 179.6
2140 Male, age 76, both hemispheres 177.0
Pretectal area
nTPM: 208.7
1816 Male, age 51, unknown 232.1
1944 Female, age 72, unknown 230.5
2667 Female, age 75, unknown 229.0
1817 Female, age 42, unknown 226.8
2007 Male, age 72, unknown 223.1
2273 Male, age 74, both hemispheres 210.5
1815 Male, age 53, unknown 204.7
2224 Female, age 72, unknown 197.3
2316 Male, age 76, right hemisphere 189.2
2825 Male, age 18, unknown 185.0
2407 Male, age 75, both hemispheres 167.6
Red nucleus
nTPM: 197.9
1821 Female, age 72, unknown 241.2
2725 Female, age 75, unknown 215.1
1954 Female, age 42, unknown 205.3
2503 Female, age 72, unknown 200.5
2823 Male, age 76, right hemisphere 197.3
2769 Male, age 72, unknown 194.8
2227 Male, age 72, unknown 194.5
2785 Male, age 18, unknown 194.0
1904 Male, age 53, unknown 193.4
1865 Male, age 51, unknown 190.5
2588 Male, age 74, left hemisphere 179.0
2584 Male, age 75, left hemisphere 168.9
Substantia nigra
nTPM: 237.8
1916 Female, age 42, unknown 299.0
2241 Male, age 72, unknown 270.5
1851 Male, age 51, unknown 260.4
1889 Female, age 72, unknown 237.4
2409 Female, age 72, unknown 233.3
2699 Male, age 18, unknown 232.4
1941 Male, age 53, unknown 230.6
2665 Male, age 74, both hemispheres 229.3
2590 Female, age 75, unknown 206.5
2583 Male, age 75, right hemisphere 178.1
Superior colliculus
nTPM: 192.3
2087 Female, age 72, unknown 221.1
1895 Male, age 76, right hemisphere 216.3
1796 Male, age 53, unknown 202.3
2261 Male, age 18, unknown 200.9
2587 Male, age 74, left hemisphere 195.5
2668 Female, age 75, unknown 185.8
1839 Male, age 51, unknown 185.0
1913 Female, age 42, unknown 174.1
1995 Male, age 72, unknown 172.4
2664 Male, age 75, both hemispheres 169.4
Ventral tegmental area
nTPM: 217.1
1915 Female, age 42, unknown 249.0
2410 Female, age 72, unknown 243.0
2218 Male, age 76, both hemispheres 240.5
1942 Male, age 51, unknown 205.6
2223 Female, age 72, unknown 183.7
2021 Male, age 53, unknown 180.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 319.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 319.5
Samples: 139

Max nTPM: 705.6
Min nTPM: 123.1
Std nTPM: 114.9
Median nTPM: 316.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 705.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 689.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 668.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 643.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 576.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 572.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 564.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 559.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 496.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 491.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 487.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 480.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 468.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 457.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 454.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 452.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 446.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 436.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 436.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 433.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 431.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 424.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 417.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 416.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 405.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 399.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 391.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 391.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 389.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 387.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 381.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 378.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 376.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 373.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 372.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 371.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 368.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 368.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 365.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 365.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 365.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 364.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 364.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 363.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 363.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 360.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 358.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 354.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 353.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 349.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 339.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 338.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 338.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 336.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 336.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 335.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 334.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 332.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 331.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 326.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 324.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 324.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 323.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 321.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 319.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 318.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 316.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 316.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 316.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 316.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 315.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 311.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 301.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 300.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 300.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 296.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 294.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 291.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 289.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 288.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 286.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 286.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 280.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 280.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 279.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 273.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 273.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 268.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 266.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 265.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 262.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 261.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 258.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 258.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 256.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 255.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 253.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 249.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 247.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 245.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 241.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 240.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 237.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 236.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 235.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 235.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 231.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 231.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 230.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 227.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 227.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 224.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 222.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 221.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 217.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 215.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 214.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 207.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 206.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 204.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 203.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 201.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 197.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 196.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 194.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 190.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 187.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 185.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 160.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 160.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 157.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 151.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 150.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 149.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 148.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 145.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 132.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 125.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 123.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 139.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 139.2
FF:10158-103A5 76 years, female 139.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 152.4
Pig sample Sample description nTPM
Midbrain
nTPM: 130.0
Samples: 4

Max nTPM: 164.8
Min nTPM: 109.1
Sample A Female 124.0
Sample B Female 109.1
Sample C Male 164.8
Sample D Male 122.0
Periaqueductal gray
nTPM: 101.2
Samples: 3

Max nTPM: 114.1
Min nTPM: 85.3
Sample B Female 104.2
Sample C Male 114.1
Sample D Male 85.3
Substantia nigra
nTPM: 116.8
Samples: 4

Max nTPM: 162.4
Min nTPM: 85.6
Sample A Female 162.4
Sample B Female 95.5
Sample C Male 123.6
Sample D Male 85.6
Superior colliculi
nTPM: 152.4
Samples: 4

Max nTPM: 184.5
Min nTPM: 122.3
Sample A Female 179.4
Sample B Female 122.3
Sample C Male 184.5
Sample D Male 123.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 798.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 798.7
Samples: 4

Max nTPM: 815.6
Min nTPM: 768.3
Sample A Male 815.6
Sample B Male 799.5
Sample C Female 768.3
Sample D Female 811.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.3
1579 Antisense, RP_040526_01_D04, Mouse strain C57BL/6J (56 days, male) 12.3
1580 Antisense, RP_040526_01_D04, Mouse strain C57BL/6J (56 days, male) 10.9

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