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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:51.1 nTPM
HPA:51.1 nTPM
GTEx:49.7 nTPM
FANTOM5:30.1 Scaled Tags Per Million
Pig:91.9 nTPM
Mouse:291.8 nTPM
Allen mouse:17.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 51.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 44.0
2019 Male, age 18, unknown 56.5
1827 Male, age 72, unknown 47.7
2586 Male, age 75, left hemisphere 47.5
2411 Female, age 72, unknown 45.5
1870 Female, age 42, unknown 43.2
2828 Female, age 72, unknown 42.3
2219 Male, age 76, both hemispheres 42.1
2666 Male, age 74, left hemisphere 41.9
1833 Male, age 53, unknown 37.7
1830 Male, age 51, unknown 36.2
Dorsal raphe nucleus
nTPM: 48.8
2298 Female, age 72, unknown 58.8
1828 Male, age 53, unknown 51.8
2047 Male, age 72, unknown 50.5
2750 Male, age 76, both hemispheres 43.0
2016 Female, age 72, unknown 39.7
Inferior colliculus
nTPM: 46.7
2097 Female, age 72, unknown 54.0
1890 Male, age 53, unknown 49.2
1848 Female, age 42, unknown 46.3
2849 Male, age 72, unknown 37.4
Median raphe nucleus
nTPM: 45.8
2220 Male, age 76, midline 45.8
Pedunculopontine tegmental nucleus
nTPM: 44.9
1921 Female, age 85, both hemispheres 52.1
2334 Male, age 80, both hemispheres 44.2
2338 Male, age 61, both hemispheres 38.4
Periaquaductal grey, anterior
nTPM: 45.3
1795 Male, age 51, unknown 46.0
1947 Male, age 18, unknown 45.1
2502 Female, age 75, unknown 44.8
Periaquaductal grey, dorsal
nTPM: 40.3
1840 Male, age 53, unknown 41.9
2464 Female, age 72, unknown 40.9
1831 Male, age 72, unknown 39.6
2850 Male, age 76, both hemispheres 38.7
Periaquaductal grey, lateral
nTPM: 39.2
2272 Male, age 74, both hemispheres 42.5
2053 Male, age 18, unknown 39.0
2140 Male, age 76, both hemispheres 36.0
Pretectal area
nTPM: 51.1
1816 Male, age 51, unknown 67.4
1817 Female, age 42, unknown 63.6
1944 Female, age 72, unknown 63.6
2007 Male, age 72, unknown 61.9
2667 Female, age 75, unknown 54.6
1815 Male, age 53, unknown 49.3
2224 Female, age 72, unknown 46.0
2273 Male, age 74, both hemispheres 43.6
2316 Male, age 76, right hemisphere 40.5
2825 Male, age 18, unknown 38.4
2407 Male, age 75, both hemispheres 33.8
Red nucleus
nTPM: 45.2
1821 Female, age 72, unknown 59.8
2785 Male, age 18, unknown 50.4
2725 Female, age 75, unknown 49.1
1954 Female, age 42, unknown 45.8
2503 Female, age 72, unknown 45.0
1904 Male, age 53, unknown 44.0
2823 Male, age 76, right hemisphere 43.9
2588 Male, age 74, left hemisphere 43.4
2227 Male, age 72, unknown 43.2
2769 Male, age 72, unknown 42.1
1865 Male, age 51, unknown 41.5
2584 Male, age 75, left hemisphere 34.0
Substantia nigra
nTPM: 50.9
1916 Female, age 42, unknown 69.1
1889 Female, age 72, unknown 59.3
1851 Male, age 51, unknown 57.9
2241 Male, age 72, unknown 55.2
1941 Male, age 53, unknown 53.4
2409 Female, age 72, unknown 48.6
2665 Male, age 74, both hemispheres 43.0
2699 Male, age 18, unknown 42.1
2590 Female, age 75, unknown 41.6
2583 Male, age 75, right hemisphere 39.2
Superior colliculus
nTPM: 43.7
2087 Female, age 72, unknown 53.4
1796 Male, age 53, unknown 48.3
1895 Male, age 76, right hemisphere 46.2
2261 Male, age 18, unknown 45.8
2587 Male, age 74, left hemisphere 45.4
2668 Female, age 75, unknown 43.1
2664 Male, age 75, both hemispheres 40.5
1995 Male, age 72, unknown 39.0
1839 Male, age 51, unknown 38.6
1913 Female, age 42, unknown 36.9
Ventral tegmental area
nTPM: 48.5
2410 Female, age 72, unknown 58.0
1915 Female, age 42, unknown 57.3
2218 Male, age 76, both hemispheres 49.5
1942 Male, age 51, unknown 46.1
2223 Female, age 72, unknown 40.3
2021 Male, age 53, unknown 39.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 49.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 49.7
Samples: 139

Max nTPM: 159.1
Min nTPM: 12.5
Std nTPM: 23.6
Median nTPM: 45.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 159.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 145.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 110.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 110.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 102.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 99.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 92.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 90.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 86.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 81.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 80.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 78.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 77.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 77.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 75.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 73.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 72.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 72.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 72.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 71.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 71.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 71.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 70.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 69.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 69.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 69.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 69.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 67.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 66.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 66.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 66.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 65.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 65.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 65.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 64.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 63.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 62.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 59.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 59.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 57.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 57.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 57.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 56.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 56.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 56.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 54.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 54.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 54.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 54.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 53.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 52.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 51.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 51.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 50.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 49.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 48.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 48.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 48.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 48.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 47.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 47.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 46.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 46.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 46.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 46.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 46.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 45.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 45.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 45.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 45.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 44.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 44.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 44.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 44.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 43.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 43.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 42.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 42.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 42.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 42.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 42.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 41.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 41.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 41.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 41.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 39.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 39.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 39.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 39.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 38.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 38.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 38.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 37.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 37.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 37.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 37.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 37.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 36.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 36.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 35.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 35.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 34.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 33.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 33.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 33.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 32.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 32.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 32.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 32.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 30.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 30.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 30.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 29.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 29.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 28.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 28.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 28.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 27.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 27.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 27.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 27.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 26.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 26.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 26.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 25.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 25.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 24.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 24.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 24.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 20.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 20.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 19.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 19.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 19.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 19.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 18.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 17.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 14.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 12.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 30.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 30.1
FF:10158-103A5 76 years, female 30.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 91.9
Pig sample Sample description nTPM
Midbrain
nTPM: 78.6
Samples: 4

Max nTPM: 106.6
Min nTPM: 55.6
Sample A Female 57.1
Sample B Female 55.6
Sample C Male 106.6
Sample D Male 94.9
Periaqueductal gray
nTPM: 59.4
Samples: 3

Max nTPM: 65.9
Min nTPM: 53.3
Sample B Female 59.0
Sample C Male 65.9
Sample D Male 53.3
Substantia nigra
nTPM: 61.9
Samples: 4

Max nTPM: 77.5
Min nTPM: 45.4
Sample A Female 77.5
Sample B Female 45.4
Sample C Male 75.0
Sample D Male 49.6
Superior colliculi
nTPM: 91.9
Samples: 4

Max nTPM: 121.3
Min nTPM: 64.6
Sample A Female 96.8
Sample B Female 64.6
Sample C Male 121.3
Sample D Male 85.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 291.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 291.8
Samples: 4

Max nTPM: 302.0
Min nTPM: 280.0
Sample A Male 289.0
Sample B Male 280.0
Sample C Female 302.0
Sample D Female 296.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 17.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.2
67870466 Antisense, RP_041018_01_D08, Mouse strain C57BL/6J (56 days, male) 21.3
75694394 Antisense, RP_060518_03_F09, Mouse strain C57BL/6J (56 days, male) 13.1

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