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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:155.2 nTPM
HPA:155.2 nTPM
GTEx:227.3 nTPM
FANTOM5:544.5 Scaled Tags Per Million
Pig:97.2 nTPM
Mouse:89.0 nTPM
Allen mouse:2.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 155.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 137.0
1870 Female, age 42, unknown 156.6
1830 Male, age 51, unknown 149.4
1833 Male, age 53, unknown 144.9
2019 Male, age 18, unknown 140.2
2411 Female, age 72, unknown 138.5
2666 Male, age 74, left hemisphere 135.3
1827 Male, age 72, unknown 135.2
2828 Female, age 72, unknown 132.6
2219 Male, age 76, both hemispheres 120.6
2586 Male, age 75, left hemisphere 117.0
Dorsal raphe nucleus
nTPM: 126.3
2750 Male, age 76, both hemispheres 145.0
2016 Female, age 72, unknown 133.4
1828 Male, age 53, unknown 126.9
2047 Male, age 72, unknown 115.2
2298 Female, age 72, unknown 110.9
Inferior colliculus
nTPM: 135.9
2849 Male, age 72, unknown 145.2
1890 Male, age 53, unknown 135.3
1848 Female, age 42, unknown 133.6
2097 Female, age 72, unknown 129.6
Median raphe nucleus
nTPM: 134.5
2220 Male, age 76, midline 134.5
Pedunculopontine tegmental nucleus
nTPM: 138.9
2334 Male, age 80, both hemispheres 143.8
2338 Male, age 61, both hemispheres 138.1
1921 Female, age 85, both hemispheres 134.9
Periaquaductal grey, anterior
nTPM: 126.4
1947 Male, age 18, unknown 132.5
2502 Female, age 75, unknown 129.4
1795 Male, age 51, unknown 117.3
Periaquaductal grey, dorsal
nTPM: 131.6
2850 Male, age 76, both hemispheres 140.7
1831 Male, age 72, unknown 133.2
2464 Female, age 72, unknown 130.5
1840 Male, age 53, unknown 122.0
Periaquaductal grey, lateral
nTPM: 129.7
2053 Male, age 18, unknown 132.9
2140 Male, age 76, both hemispheres 130.7
2272 Male, age 74, both hemispheres 125.5
Pretectal area
nTPM: 133.2
1815 Male, age 53, unknown 143.4
2407 Male, age 75, both hemispheres 140.0
2316 Male, age 76, right hemisphere 137.5
2825 Male, age 18, unknown 135.3
1944 Female, age 72, unknown 135.2
2667 Female, age 75, unknown 134.7
1817 Female, age 42, unknown 131.6
1816 Male, age 51, unknown 129.2
2007 Male, age 72, unknown 128.1
2273 Male, age 74, both hemispheres 126.6
2224 Female, age 72, unknown 123.3
Red nucleus
nTPM: 155.2
1865 Male, age 51, unknown 171.3
2823 Male, age 76, right hemisphere 161.2
2503 Female, age 72, unknown 161.0
1904 Male, age 53, unknown 159.5
1821 Female, age 72, unknown 156.3
1954 Female, age 42, unknown 155.2
2769 Male, age 72, unknown 152.8
2227 Male, age 72, unknown 152.1
2725 Female, age 75, unknown 151.8
2588 Male, age 74, left hemisphere 149.0
2584 Male, age 75, left hemisphere 147.4
2785 Male, age 18, unknown 145.0
Substantia nigra
nTPM: 134.6
2583 Male, age 75, right hemisphere 146.7
2409 Female, age 72, unknown 146.4
2590 Female, age 75, unknown 145.6
1889 Female, age 72, unknown 136.4
2699 Male, age 18, unknown 134.3
2241 Male, age 72, unknown 131.7
1941 Male, age 53, unknown 129.8
2665 Male, age 74, both hemispheres 129.8
1851 Male, age 51, unknown 129.4
1916 Female, age 42, unknown 116.0
Superior colliculus
nTPM: 137.4
1913 Female, age 42, unknown 164.6
1995 Male, age 72, unknown 152.2
1895 Male, age 76, right hemisphere 144.7
2587 Male, age 74, left hemisphere 141.7
1839 Male, age 51, unknown 136.4
2087 Female, age 72, unknown 133.7
1796 Male, age 53, unknown 128.8
2261 Male, age 18, unknown 128.7
2668 Female, age 75, unknown 123.7
2664 Male, age 75, both hemispheres 119.5
Ventral tegmental area
nTPM: 132.3
2223 Female, age 72, unknown 141.1
2410 Female, age 72, unknown 137.4
2218 Male, age 76, both hemispheres 132.1
2021 Male, age 53, unknown 131.7
1942 Male, age 51, unknown 127.4
1915 Female, age 42, unknown 123.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 227.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 227.3
Samples: 139

Max nTPM: 478.0
Min nTPM: 101.7
Std nTPM: 63.7
Median nTPM: 220.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 478.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 470.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 389.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 381.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 378.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 375.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 364.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 342.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 338.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 331.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 326.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 324.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 322.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 322.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 307.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 298.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 289.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 285.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 281.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 277.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 276.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 275.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 275.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 275.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 270.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 267.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 267.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 265.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 265.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 263.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 262.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 261.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 260.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 259.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 253.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 253.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 251.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 251.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 250.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 250.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 250.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 249.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 247.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 246.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 246.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 246.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 244.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 243.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 243.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 239.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 236.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 235.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 234.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 231.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 231.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 229.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 227.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 227.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 226.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 226.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 226.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 225.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 224.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 224.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 223.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 223.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 222.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 222.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 221.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 220.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 220.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 219.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 217.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 216.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 216.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 213.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 211.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 211.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 210.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 209.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 208.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 207.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 207.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 207.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 203.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 203.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 202.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 199.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 197.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 197.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 195.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 195.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 194.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 194.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 193.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 193.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 193.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 192.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 190.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 190.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 187.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 186.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 184.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 183.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 183.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 182.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 181.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 181.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 181.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 181.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 179.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 179.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 178.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 178.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 177.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 175.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 173.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 172.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 172.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 171.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 170.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 170.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 166.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 163.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 161.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 159.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 159.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 153.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 149.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 146.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 144.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 143.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 138.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 133.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 133.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 122.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 116.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 116.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 101.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 544.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 544.5
FF:10158-103A5 76 years, female 544.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 97.2
Pig sample Sample description nTPM
Midbrain
nTPM: 97.2
Samples: 4

Max nTPM: 128.8
Min nTPM: 83.0
Sample A Female 128.8
Sample B Female 91.5
Sample C Male 85.5
Sample D Male 83.0
Periaqueductal gray
nTPM: 84.4
Samples: 3

Max nTPM: 86.2
Min nTPM: 82.6
Sample B Female 82.6
Sample C Male 86.2
Sample D Male 84.5
Substantia nigra
nTPM: 84.9
Samples: 4

Max nTPM: 96.7
Min nTPM: 72.1
Sample A Female 82.6
Sample B Female 72.1
Sample C Male 88.1
Sample D Male 96.7
Superior colliculi
nTPM: 84.4
Samples: 4

Max nTPM: 96.2
Min nTPM: 62.9
Sample A Female 85.0
Sample B Female 62.9
Sample C Male 96.2
Sample D Male 93.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 89.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 89.0
Samples: 4

Max nTPM: 101.2
Min nTPM: 80.0
Sample A Male 101.2
Sample B Male 87.8
Sample C Female 86.9
Sample D Female 80.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.3
68445161 Antisense, RP_050111_02_H06, Mouse strain C57BL/6J (56 days, male) 4.5
572 Antisense, RP_Baylor_103185, Mouse strain C57BL/6J (56 days, male) 0.2
571 Antisense, RP_Baylor_103185, Mouse strain C57BL/6J (56 days, male) 0.0

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