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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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76.078
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:25.3 nTPM
HPA:25.3 nTPM
FANTOM5:126.2 Scaled Tags Per Million
Pig:39.3 nTPM

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody HPA006563
Pons mean intensity 76.078
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 16.797
Parabrachial nucleus 35.229
Principle sensory trigeminal nucleus 16.420
Locus coeruleus 76.078
Pontine nucleus 31.859
Vestibular nucleus 16.627
Pontine reticular nucleus, oral 9.872
Lateral lemniscus 20.682
Superior paraolivary nucleus 6.956

PONS - HPA Brain RNA-seq
Max nTPM 25.3
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 13.8
2301 Female, age 85, both hemispheres 16.0
1984 Male, age 76, both hemispheres 14.5
2090 Male, age 80, both hemispheres 13.3
2188 Female, age 91, both hemispheres 11.5
Dorsal cochlear nucleus
nTPM: 21.3
2802 Male, age 74, right hemisphere 28.9
2370 Male, age 61, both hemispheres 23.5
2378 Male, age 80, both hemispheres 19.4
2058 Male, age 76, both hemispheres 18.8
2187 Female, age 91, both hemispheres 15.9
Dorsal tegmental nucleus
nTPM: 21.5
2083 Male, age 80, both hemispheres 22.5
1936 Male, age 76, left hemisphere 22.2
2326 Male, age 74, both hemispheres 22.0
2358 Male, age 61, both hemispheres 19.2
Dorsolateral tegmental area
nTPM: 18.9
2654 Male, age 80, both hemispheres 23.4
2751 Female, age 85, both hemispheres 19.3
2360 Male, age 74, both hemispheres 18.0
2337 Male, age 61, both hemispheres 17.1
2141 Male, age 76, both hemispheres 16.8
Kolliker-Fuse nucleus
nTPM: 22.1
2315 Male, age 76, right hemisphere 38.1
2163 Male, age 80, both hemispheres 16.8
2793 Female, age 91, left hemisphere 11.4
Lateral lemniscal nuclei
nTPM: 12.0
2453 Male, age 74, right hemisphere 14.1
2169 Male, age 76, both hemispheres 13.0
2036 Male, age 80, both hemispheres 11.6
2746 Female, age 85, left hemisphere 10.8
2320 Female, age 91, left hemisphere 10.5
Lateral parabrachial nucleus
nTPM: 18.5
2792 Male, age 76, both hemispheres 22.2
2139 Female, age 85, right hemisphere 19.2
2790 Male, age 61, both hemispheres 18.1
2013 Male, age 80, both hemispheres 14.3
Lateral vestibular nucleus
nTPM: 18.6
2184 Male, age 76, both hemispheres 18.7
2311 Male, age 80, both hemispheres 18.6
Locus coeruleus
nTPM: 20.7
2720 Male, age 74, both hemispheres 21.9
2014 Male, age 55, unknown 21.7
1980 Male, age 76, both hemispheres 21.6
2788 Male, age 74, unknown 21.6
2123 Female, age 91, both hemispheres 20.8
2317 Female, age 72, unknown 20.6
2162 Male, age 80, both hemispheres 16.8
Medial olivary nucleus
nTPM: 25.3
2138 Female, age 91, both hemispheres 34.8
1962 Male, age 76, both hemispheres 25.4
1943 Male, age 61, both hemispheres 20.9
2851 Male, age 80, both hemispheres 20.2
Medial parabrachial nucleus
nTPM: 17.2
2786 Male, age 76, both hemispheres 20.0
2156 Male, age 61, both hemispheres 19.2
2463 Female, age 85, right hemisphere 16.5
2170 Female, age 91, both hemispheres 15.2
2854 Male, age 80, both hemispheres 15.2
Medial periolivary nuclei
nTPM: 12.9
2791 Male, age 74, right hemisphere 17.6
2063 Male, age 76, both hemispheres 13.9
2458 Female, age 91, both hemispheres 11.7
2081 Male, age 80, both hemispheres 11.0
2171 Female, age 85, both hemispheres 10.5
Motor facial nucleus
nTPM: 15.0
2795 Female, age 91, both hemispheres 27.1
2126 Male, age 61, both hemispheres 15.5
2365 Male, age 74, right hemisphere 15.1
2062 Male, age 76, both hemispheres 14.9
2697 Female, age 85, both hemispheres 9.1
2327 Male, age 80, both hemispheres 8.5
Motor trigeminal nucleus
nTPM: 14.3
2309 Male, age 76, both hemispheres 18.6
2335 Male, age 61, both hemispheres 16.4
2560 Male, age 74, both hemispheres 15.0
2321 Female, age 91, both hemispheres 11.3
2079 Male, age 80, both hemispheres 10.2
Nuclei of the trapezoid body
nTPM: 12.6
2368 Female, age 91, both hemispheres 18.2
1983 Male, age 76, both hemispheres 14.3
2166 Male, age 80, both hemispheres 12.0
2735 Female, age 85, both hemispheres 10.8
2159 Male, age 61, both hemispheres 7.6
Paramedian reticular nucleus
nTPM: 15.9
2052 Male, age 76, both hemispheres 18.0
2057 Male, age 80, both hemispheres 17.1
2313 Male, age 61, both hemispheres 15.7
2050 Female, age 85, both hemispheres 12.9
Pontine nuclei
nTPM: 10.0
1863 Male, age 55, unknown 13.1
2109 Female, age 72, unknown 12.0
1968 Male, age 76, left hemisphere 11.8
2115 Male, age 80, left hemisphere 10.8
2319 Female, age 91, both hemispheres 10.5
2454 Male, age 74, left hemisphere 9.5
2787 Female, age 85, both hemispheres 7.4
2727 Male, age 61, right hemisphere 5.2
Pontine raphe nucleus
nTPM: 17.4
2853 Male, age 76, midline 22.2
2122 Female, age 85, midline 12.6
Posteroventral cochlear nucleus
nTPM: 16.4
2371 Male, age 61, both hemispheres 23.9
2070 Male, age 76, both hemispheres 16.6
2752 Female, age 85, both hemispheres 16.1
2341 Male, age 80, both hemispheres 14.3
2135 Female, age 91, both hemispheres 10.9
Principal sensory trigeminal nucleus
nTPM: 12.4
2324 Male, age 76, both hemispheres 22.2
2008 Male, age 80, left hemisphere 9.8
2367 Female, age 91, left hemisphere 9.6
2158 Male, age 61, both hemispheres 7.9
Reticular pontine nucleus, caudal
nTPM: 13.2
2092 Male, age 76, both hemispheres 16.7
2559 Male, age 74, both hemispheres 13.6
2457 Female, age 91, both hemispheres 13.2
2332 Male, age 80, right hemisphere 9.4
Reticular pontine nucleus, oral
nTPM: 14.9
1939 Male, age 80, both hemispheres 21.7
2167 Male, age 76, both hemispheres 19.9
2012 Female, age 85, both hemispheres 13.0
2366 Female, age 91, both hemispheres 11.1
2361 Male, age 74, both hemispheres 9.0
Reticulotegmental nucleus
nTPM: 17.4
2333 Male, age 80, both hemispheres 19.3
2322 Female, age 91, both hemispheres 18.2
2452 Male, age 74, both hemispheres 18.0
2325 Male, age 76, both hemispheres 14.2
Spinal trigeminal nucleus, oral
nTPM: 16.2
1978 Male, age 76, both hemispheres 16.9
2164 Male, age 80, both hemispheres 16.0
2737 Female, age 85, both hemispheres 15.7
Subcoeruleus area
nTPM: 17.9
2451 Male, age 74, both hemispheres 22.6
2369 Female, age 85, left hemisphere 19.9
2323 Female, age 91, left hemisphere 17.9
1958 Male, age 80, both hemispheres 16.6
2089 Male, age 76, left hemisphere 12.4
Superior olive
nTPM: 12.2
2364 Male, age 74, right hemisphere 15.3
2020 Male, age 76, both hemispheres 13.3
2561 Female, age 91, both hemispheres 12.2
2329 Male, age 80, right hemisphere 11.3
1875 Female, age 85, both hemispheres 9.1
Superior vestibular nucleus
nTPM: 21.9
2061 Male, age 76, both hemispheres 23.5
2383 Male, age 74, both hemispheres 22.6
2015 Male, age 80, both hemispheres 19.5
Ventral periolivary nuclei
nTPM: 12.4
2023 Male, age 76, both hemispheres 13.6
2130 Female, age 85, both hemispheres 13.6
2165 Male, age 80, both hemispheres 12.7
2794 Female, age 91, left hemisphere 9.6
Ventrolateral tegmental area, A5 NE cell group
nTPM: 15.7
2359 Male, age 61, both hemispheres 21.0
2456 Female, age 91, both hemispheres 16.7
2840 Female, age 85, both hemispheres 15.1
1959 Male, age 76, both hemispheres 14.5
2449 Male, age 74, both hemispheres 13.7
2161 Male, age 80, both hemispheres 13.2

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 126.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 126.2
FF:10182-103D2 60 years, female 140.9
FF:10165-103B3 76 years, female 111.5
Pons
Scaled Tags Per Million: 69.8
FF:10033-101E6 18-54 years, mixed 69.8

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 39.3
Pig sample Sample description nTPM
Pons
nTPM: 39.3
Samples: 4

Max nTPM: 45.2
Min nTPM: 35.1
Sample A Female 45.2
Sample B Female 35.1
Sample C Male 38.2
Sample D Male 38.8

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.