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AQP4
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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66.214
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:333.3 nTPM
HPA:333.3 nTPM
FANTOM5:645.6 Scaled Tags Per Million
Pig:542.8 nTPM
Allen mouse:5.1 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody CAB005079
Pons mean intensity 66.214
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 25.077
Parabrachial nucleus 66.214
Principle sensory trigeminal nucleus 37.887
Locus coeruleus 39.258
Pontine nucleus 34.922
Vestibular nucleus 28.961
Pontine reticular nucleus, oral 19.950
Lateral lemniscus 15.124
Superior paraolivary nucleus 16.565

PONS - HPA Brain RNA-seq
Max nTPM 333.3
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 154.1
2301 Female, age 85, both hemispheres 187.0
2090 Male, age 80, both hemispheres 166.4
1984 Male, age 76, both hemispheres 159.5
2188 Female, age 91, both hemispheres 103.6
Dorsal cochlear nucleus
nTPM: 194.8
2370 Male, age 61, both hemispheres 287.1
2058 Male, age 76, both hemispheres 198.8
2378 Male, age 80, both hemispheres 176.0
2802 Male, age 74, right hemisphere 164.8
2187 Female, age 91, both hemispheres 147.4
Dorsal tegmental nucleus
nTPM: 199.1
1936 Male, age 76, left hemisphere 235.3
2083 Male, age 80, both hemispheres 219.9
2326 Male, age 74, both hemispheres 200.6
2358 Male, age 61, both hemispheres 140.7
Dorsolateral tegmental area
nTPM: 220.6
2360 Male, age 74, both hemispheres 370.4
2751 Female, age 85, both hemispheres 223.1
2654 Male, age 80, both hemispheres 213.0
2141 Male, age 76, both hemispheres 180.4
2337 Male, age 61, both hemispheres 116.1
Kolliker-Fuse nucleus
nTPM: 204.4
2315 Male, age 76, right hemisphere 380.7
2163 Male, age 80, both hemispheres 156.2
2793 Female, age 91, left hemisphere 76.5
Lateral lemniscal nuclei
nTPM: 115.5
2746 Female, age 85, left hemisphere 155.4
2169 Male, age 76, both hemispheres 141.1
2036 Male, age 80, both hemispheres 124.9
2453 Male, age 74, right hemisphere 83.9
2320 Female, age 91, left hemisphere 72.4
Lateral parabrachial nucleus
nTPM: 201.7
2139 Female, age 85, right hemisphere 285.0
2792 Male, age 76, both hemispheres 242.4
2013 Male, age 80, both hemispheres 183.8
2790 Male, age 61, both hemispheres 95.5
Lateral vestibular nucleus
nTPM: 187.0
2311 Male, age 80, both hemispheres 188.8
2184 Male, age 76, both hemispheres 185.3
Locus coeruleus
nTPM: 190.3
2317 Female, age 72, unknown 268.8
2788 Male, age 74, unknown 237.0
2014 Male, age 55, unknown 197.6
1980 Male, age 76, both hemispheres 192.2
2123 Female, age 91, both hemispheres 191.3
2162 Male, age 80, both hemispheres 146.0
2720 Male, age 74, both hemispheres 99.0
Medial olivary nucleus
nTPM: 270.8
2138 Female, age 91, both hemispheres 351.8
1943 Male, age 61, both hemispheres 288.1
1962 Male, age 76, both hemispheres 248.6
2851 Male, age 80, both hemispheres 194.9
Medial parabrachial nucleus
nTPM: 163.2
2463 Female, age 85, right hemisphere 196.4
2786 Male, age 76, both hemispheres 178.2
2156 Male, age 61, both hemispheres 166.4
2170 Female, age 91, both hemispheres 153.3
2854 Male, age 80, both hemispheres 121.8
Medial periolivary nuclei
nTPM: 160.1
2791 Male, age 74, right hemisphere 314.2
2063 Male, age 76, both hemispheres 166.4
2171 Female, age 85, both hemispheres 141.9
2081 Male, age 80, both hemispheres 97.4
2458 Female, age 91, both hemispheres 80.7
Motor facial nucleus
nTPM: 133.6
2365 Male, age 74, right hemisphere 199.2
2062 Male, age 76, both hemispheres 184.6
2126 Male, age 61, both hemispheres 140.1
2795 Female, age 91, both hemispheres 130.5
2697 Female, age 85, both hemispheres 87.2
2327 Male, age 80, both hemispheres 60.2
Motor trigeminal nucleus
nTPM: 123.8
2309 Male, age 76, both hemispheres 193.1
2335 Male, age 61, both hemispheres 175.9
2079 Male, age 80, both hemispheres 96.2
2321 Female, age 91, both hemispheres 83.3
2560 Male, age 74, both hemispheres 70.7
Nuclei of the trapezoid body
nTPM: 128.3
1983 Male, age 76, both hemispheres 172.9
2735 Female, age 85, both hemispheres 146.5
2368 Female, age 91, both hemispheres 122.8
2159 Male, age 61, both hemispheres 107.1
2166 Male, age 80, both hemispheres 92.2
Paramedian reticular nucleus
nTPM: 176.7
2057 Male, age 80, both hemispheres 208.3
2052 Male, age 76, both hemispheres 191.0
2313 Male, age 61, both hemispheres 175.8
2050 Female, age 85, both hemispheres 131.5
Pontine nuclei
nTPM: 102.9
1863 Male, age 55, unknown 153.7
1968 Male, age 76, left hemisphere 133.2
2115 Male, age 80, left hemisphere 105.1
2787 Female, age 85, both hemispheres 104.8
2109 Female, age 72, unknown 101.4
2727 Male, age 61, right hemisphere 88.8
2319 Female, age 91, both hemispheres 88.3
2454 Male, age 74, left hemisphere 47.8
Pontine raphe nucleus
nTPM: 154.4
2853 Male, age 76, midline 175.8
2122 Female, age 85, midline 133.0
Posteroventral cochlear nucleus
nTPM: 171.0
2371 Male, age 61, both hemispheres 273.4
2752 Female, age 85, both hemispheres 182.2
2070 Male, age 76, both hemispheres 153.2
2341 Male, age 80, both hemispheres 145.6
2135 Female, age 91, both hemispheres 100.6
Principal sensory trigeminal nucleus
nTPM: 122.1
2324 Male, age 76, both hemispheres 209.6
2158 Male, age 61, both hemispheres 109.5
2008 Male, age 80, left hemisphere 101.0
2367 Female, age 91, left hemisphere 68.2
Reticular pontine nucleus, caudal
nTPM: 98.1
2092 Male, age 76, both hemispheres 194.7
2457 Female, age 91, both hemispheres 69.6
2332 Male, age 80, right hemisphere 64.1
2559 Male, age 74, both hemispheres 63.9
Reticular pontine nucleus, oral
nTPM: 141.2
1939 Male, age 80, both hemispheres 233.5
2167 Male, age 76, both hemispheres 181.6
2012 Female, age 85, both hemispheres 174.0
2366 Female, age 91, both hemispheres 72.6
2361 Male, age 74, both hemispheres 44.1
Reticulotegmental nucleus
nTPM: 135.7
2325 Male, age 76, both hemispheres 172.2
2333 Male, age 80, both hemispheres 150.6
2322 Female, age 91, both hemispheres 126.5
2452 Male, age 74, both hemispheres 93.4
Spinal trigeminal nucleus, oral
nTPM: 143.4
2737 Female, age 85, both hemispheres 172.2
1978 Male, age 76, both hemispheres 158.5
2164 Male, age 80, both hemispheres 99.6
Subcoeruleus area
nTPM: 162.2
2369 Female, age 85, left hemisphere 222.9
1958 Male, age 80, both hemispheres 175.5
2323 Female, age 91, left hemisphere 150.5
2451 Male, age 74, both hemispheres 134.8
2089 Male, age 76, left hemisphere 127.4
Superior olive
nTPM: 145.1
2364 Male, age 74, right hemisphere 313.0
2020 Male, age 76, both hemispheres 145.1
1875 Female, age 85, both hemispheres 107.7
2561 Female, age 91, both hemispheres 81.1
2329 Male, age 80, right hemisphere 78.4
Superior vestibular nucleus
nTPM: 333.3
2383 Male, age 74, both hemispheres 495.9
2061 Male, age 76, both hemispheres 265.4
2015 Male, age 80, both hemispheres 238.6
Ventral periolivary nuclei
nTPM: 131.6
2130 Female, age 85, both hemispheres 165.1
2023 Male, age 76, both hemispheres 152.2
2165 Male, age 80, both hemispheres 124.7
2794 Female, age 91, left hemisphere 84.3
Ventrolateral tegmental area, A5 NE cell group
nTPM: 138.7
2359 Male, age 61, both hemispheres 188.8
1959 Male, age 76, both hemispheres 152.7
2840 Female, age 85, both hemispheres 152.0
2449 Male, age 74, both hemispheres 126.0
2456 Female, age 91, both hemispheres 107.4
2161 Male, age 80, both hemispheres 105.4

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 645.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 645.6
FF:10165-103B3 76 years, female 736.3
FF:10182-103D2 60 years, female 554.8
Pons
Scaled Tags Per Million: 474.2
FF:10033-101E6 18-54 years, mixed 474.2

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 542.8
Pig sample Sample description nTPM
Pons
nTPM: 542.8
Samples: 4

Max nTPM: 666.7
Min nTPM: 463.4
Sample A Female 477.7
Sample B Female 463.4
Sample C Male 563.5
Sample D Male 666.7

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 5.1
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 5.1
77454660 Antisense, RP_070129_01_C02, Mouse strain C57BL/6J (56 days, male) 6.2
79556722 Antisense, RP_071204_01_E02, Mouse strain C57BL/6J (56 days, male) 4.8
109 Antisense, RP_040324_01_F07, Mouse strain C57BL/6J (56 days, male) 4.2
108 Antisense, RP_040324_01_F07, Mouse strain C57BL/6J (56 days, male) 4.2

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.