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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:1296.9 nTPM
HPA:1296.9 nTPM
GTEx:760.2 nTPM
FANTOM5:689.1 Scaled Tags Per Million
Pig:569.7 nTPM
Mouse:738.8 nTPM
Allen mouse:9.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 1296.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1243.9
2411 Female, age 72, unknown 1298.8
2586 Male, age 75, left hemisphere 1297.8
2828 Female, age 72, unknown 1249.7
2019 Male, age 18, unknown 1244.7
1827 Male, age 72, unknown 1235.0
1833 Male, age 53, unknown 1232.3
2219 Male, age 76, both hemispheres 1227.8
1870 Female, age 42, unknown 1226.9
1830 Male, age 51, unknown 1222.5
2666 Male, age 74, left hemisphere 1202.9
Dorsal raphe nucleus
nTPM: 1226.4
2750 Male, age 76, both hemispheres 1258.7
2298 Female, age 72, unknown 1248.0
1828 Male, age 53, unknown 1218.0
2047 Male, age 72, unknown 1206.9
2016 Female, age 72, unknown 1200.2
Inferior colliculus
nTPM: 1200.8
2097 Female, age 72, unknown 1225.0
1890 Male, age 53, unknown 1202.7
1848 Female, age 42, unknown 1192.5
2849 Male, age 72, unknown 1182.9
Median raphe nucleus
nTPM: 1238.5
2220 Male, age 76, midline 1238.5
Pedunculopontine tegmental nucleus
nTPM: 1232.8
2334 Male, age 80, both hemispheres 1258.0
1921 Female, age 85, both hemispheres 1250.2
2338 Male, age 61, both hemispheres 1190.1
Periaquaductal grey, anterior
nTPM: 1253.9
2502 Female, age 75, unknown 1261.7
1947 Male, age 18, unknown 1259.5
1795 Male, age 51, unknown 1240.6
Periaquaductal grey, dorsal
nTPM: 1191.7
2464 Female, age 72, unknown 1208.6
1840 Male, age 53, unknown 1201.0
2850 Male, age 76, both hemispheres 1179.7
1831 Male, age 72, unknown 1177.7
Periaquaductal grey, lateral
nTPM: 1186.8
2140 Male, age 76, both hemispheres 1192.5
2053 Male, age 18, unknown 1190.4
2272 Male, age 74, both hemispheres 1177.6
Pretectal area
nTPM: 1234.6
1817 Female, age 42, unknown 1278.1
1944 Female, age 72, unknown 1274.7
1815 Male, age 53, unknown 1273.9
2007 Male, age 72, unknown 1272.3
1816 Male, age 51, unknown 1270.4
2667 Female, age 75, unknown 1214.7
2224 Female, age 72, unknown 1213.2
2825 Male, age 18, unknown 1213.0
2316 Male, age 76, right hemisphere 1204.0
2273 Male, age 74, both hemispheres 1189.0
2407 Male, age 75, both hemispheres 1177.1
Red nucleus
nTPM: 1268.3
2503 Female, age 72, unknown 1303.7
1821 Female, age 72, unknown 1291.7
2227 Male, age 72, unknown 1283.7
1904 Male, age 53, unknown 1282.6
1865 Male, age 51, unknown 1278.2
2769 Male, age 72, unknown 1277.4
2725 Female, age 75, unknown 1277.2
2785 Male, age 18, unknown 1267.0
1954 Female, age 42, unknown 1265.5
2588 Male, age 74, left hemisphere 1264.2
2823 Male, age 76, right hemisphere 1236.5
2584 Male, age 75, left hemisphere 1191.7
Substantia nigra
nTPM: 1296.9
1851 Male, age 51, unknown 1370.0
1916 Female, age 42, unknown 1344.0
2665 Male, age 74, both hemispheres 1329.7
2241 Male, age 72, unknown 1296.2
2699 Male, age 18, unknown 1294.7
2409 Female, age 72, unknown 1276.0
2583 Male, age 75, right hemisphere 1274.9
1941 Male, age 53, unknown 1272.5
1889 Female, age 72, unknown 1256.9
2590 Female, age 75, unknown 1254.1
Superior colliculus
nTPM: 1242.8
2668 Female, age 75, unknown 1281.5
2087 Female, age 72, unknown 1278.5
1796 Male, age 53, unknown 1260.8
1913 Female, age 42, unknown 1250.3
2261 Male, age 18, unknown 1248.5
1995 Male, age 72, unknown 1244.1
2664 Male, age 75, both hemispheres 1226.1
2587 Male, age 74, left hemisphere 1221.1
1895 Male, age 76, right hemisphere 1209.1
1839 Male, age 51, unknown 1208.1
Ventral tegmental area
nTPM: 1279.9
2410 Female, age 72, unknown 1336.6
1915 Female, age 42, unknown 1316.9
2223 Female, age 72, unknown 1292.2
2218 Male, age 76, both hemispheres 1269.1
1942 Male, age 51, unknown 1241.4
2021 Male, age 53, unknown 1223.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 760.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 760.2
Samples: 139

Max nTPM: 1683.1
Min nTPM: 327.2
Std nTPM: 218.3
Median nTPM: 747.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1683.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1444.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1440.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1431.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1191.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1187.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1169.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1169.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1159.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1127.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1112.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1069.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1055.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1052.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1046.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1003.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 994.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 973.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 956.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 955.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 935.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 927.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 916.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 904.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 901.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 897.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 896.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 884.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 877.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 875.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 873.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 867.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 863.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 848.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 848.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 844.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 837.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 834.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 833.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 832.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 830.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 829.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 823.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 821.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 818.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 815.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 808.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 805.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 804.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 795.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 785.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 780.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 780.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 771.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 771.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 767.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 766.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 765.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 765.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 764.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 761.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 761.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 756.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 756.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 754.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 751.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 750.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 749.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 749.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 747.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 740.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 739.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 736.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 729.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 725.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 722.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 705.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 705.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 703.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 702.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 702.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 702.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 700.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 698.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 694.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 688.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 686.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 671.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 668.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 662.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 661.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 659.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 659.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 654.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 645.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 644.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 642.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 642.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 638.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 632.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 630.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 621.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 621.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 615.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 612.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 611.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 610.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 610.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 608.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 607.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 594.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 594.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 592.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 591.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 584.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 579.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 570.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 569.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 566.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 547.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 541.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 540.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 537.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 535.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 534.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 528.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 519.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 508.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 504.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 494.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 485.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 479.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 472.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 458.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 434.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 407.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 384.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 333.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 327.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 689.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 689.1
FF:10158-103A5 76 years, female 689.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 569.7
Pig sample Sample description nTPM
Midbrain
nTPM: 503.6
Samples: 4

Max nTPM: 596.8
Min nTPM: 361.4
Sample A Female 596.8
Sample B Female 466.2
Sample C Male 590.1
Sample D Male 361.4
Periaqueductal gray
nTPM: 326.9
Samples: 3

Max nTPM: 363.3
Min nTPM: 301.4
Sample B Female 316.0
Sample C Male 363.3
Sample D Male 301.4
Substantia nigra
nTPM: 569.7
Samples: 4

Max nTPM: 853.2
Min nTPM: 377.8
Sample A Female 853.2
Sample B Female 448.9
Sample C Male 598.7
Sample D Male 377.8
Superior colliculi
nTPM: 552.0
Samples: 4

Max nTPM: 640.6
Min nTPM: 474.8
Sample A Female 640.6
Sample B Female 490.6
Sample C Male 601.8
Sample D Male 474.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 738.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 738.8
Samples: 4

Max nTPM: 855.2
Min nTPM: 644.4
Sample A Male 855.2
Sample B Male 691.2
Sample C Female 644.4
Sample D Female 764.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 9.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.4
69873540 Antisense, RP_050512_01_E03, Mouse strain C57BL/6J (56 days, male) 9.4

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