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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:37.1 nTPM
HPA:37.1 nTPM
GTEx:84.3 nTPM
FANTOM5:65.2 Scaled Tags Per Million
Pig:42.9 nTPM
Mouse:112.9 nTPM
Allen mouse:14.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 37.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 36.5
2586 Male, age 75, left hemisphere 49.3
2666 Male, age 74, left hemisphere 40.5
1870 Female, age 42, unknown 37.2
2828 Female, age 72, unknown 36.7
2019 Male, age 18, unknown 36.2
2411 Female, age 72, unknown 36.2
1827 Male, age 72, unknown 35.4
1830 Male, age 51, unknown 33.3
1833 Male, age 53, unknown 32.9
2219 Male, age 76, both hemispheres 27.5
Dorsal raphe nucleus
nTPM: 36.6
2298 Female, age 72, unknown 40.4
1828 Male, age 53, unknown 37.0
2047 Male, age 72, unknown 36.7
2016 Female, age 72, unknown 34.8
2750 Male, age 76, both hemispheres 34.1
Inferior colliculus
nTPM: 32.9
1848 Female, age 42, unknown 34.2
2097 Female, age 72, unknown 33.9
1890 Male, age 53, unknown 32.1
2849 Male, age 72, unknown 31.5
Median raphe nucleus
nTPM: 33.8
2220 Male, age 76, midline 33.8
Pedunculopontine tegmental nucleus
nTPM: 37.1
2338 Male, age 61, both hemispheres 43.6
2334 Male, age 80, both hemispheres 35.9
1921 Female, age 85, both hemispheres 31.7
Periaquaductal grey, anterior
nTPM: 36.7
1947 Male, age 18, unknown 37.6
2502 Female, age 75, unknown 36.7
1795 Male, age 51, unknown 35.8
Periaquaductal grey, dorsal
nTPM: 32.0
1840 Male, age 53, unknown 33.7
2850 Male, age 76, both hemispheres 33.5
1831 Male, age 72, unknown 32.5
2464 Female, age 72, unknown 28.4
Periaquaductal grey, lateral
nTPM: 32.0
2272 Male, age 74, both hemispheres 32.5
2053 Male, age 18, unknown 32.2
2140 Male, age 76, both hemispheres 31.2
Pretectal area
nTPM: 34.9
1817 Female, age 42, unknown 39.5
2007 Male, age 72, unknown 38.1
1815 Male, age 53, unknown 37.9
2224 Female, age 72, unknown 36.6
1944 Female, age 72, unknown 36.3
2825 Male, age 18, unknown 36.0
1816 Male, age 51, unknown 35.9
2273 Male, age 74, both hemispheres 34.9
2667 Female, age 75, unknown 33.1
2407 Male, age 75, both hemispheres 28.5
2316 Male, age 76, right hemisphere 27.3
Red nucleus
nTPM: 36.0
1821 Female, age 72, unknown 39.7
1954 Female, age 42, unknown 39.4
2725 Female, age 75, unknown 37.1
2503 Female, age 72, unknown 37.0
2584 Male, age 75, left hemisphere 37.0
1904 Male, age 53, unknown 36.7
2785 Male, age 18, unknown 36.6
2769 Male, age 72, unknown 36.2
1865 Male, age 51, unknown 35.8
2227 Male, age 72, unknown 35.2
2588 Male, age 74, left hemisphere 31.4
2823 Male, age 76, right hemisphere 30.3
Substantia nigra
nTPM: 35.5
1916 Female, age 42, unknown 41.2
1851 Male, age 51, unknown 37.9
2665 Male, age 74, both hemispheres 37.9
2583 Male, age 75, right hemisphere 37.8
1889 Female, age 72, unknown 37.3
2590 Female, age 75, unknown 36.1
1941 Male, age 53, unknown 33.1
2699 Male, age 18, unknown 32.8
2241 Male, age 72, unknown 30.6
2409 Female, age 72, unknown 30.6
Superior colliculus
nTPM: 33.7
1995 Male, age 72, unknown 37.3
1913 Female, age 42, unknown 36.8
1796 Male, age 53, unknown 35.1
2664 Male, age 75, both hemispheres 33.8
2087 Female, age 72, unknown 33.3
2668 Female, age 75, unknown 33.2
2261 Male, age 18, unknown 32.9
1839 Male, age 51, unknown 32.5
2587 Male, age 74, left hemisphere 31.9
1895 Male, age 76, right hemisphere 29.9
Ventral tegmental area
nTPM: 36.4
1915 Female, age 42, unknown 39.9
1942 Male, age 51, unknown 37.7
2410 Female, age 72, unknown 36.6
2021 Male, age 53, unknown 35.0
2223 Female, age 72, unknown 34.8
2218 Male, age 76, both hemispheres 34.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 84.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 84.3
Samples: 139

Max nTPM: 175.1
Min nTPM: 40.8
Std nTPM: 22.1
Median nTPM: 80.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 175.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 160.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 159.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 136.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 133.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 132.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 126.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 123.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 117.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 117.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 115.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 114.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 113.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 112.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 112.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 110.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 108.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 107.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 106.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 106.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 105.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 102.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 102.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 101.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 101.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 100.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 99.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 99.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 99.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 98.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 98.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 97.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 97.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 96.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 95.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 93.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 92.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 92.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 92.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 91.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 91.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 89.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 89.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 89.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 88.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 88.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 88.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 88.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 87.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 87.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 87.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 87.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 87.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 87.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 86.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 86.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 85.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 85.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 84.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 84.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 83.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 83.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 83.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 82.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 82.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 81.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 81.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 81.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 81.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 80.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 80.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 80.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 80.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 80.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 80.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 80.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 79.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 79.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 79.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 78.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 78.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 78.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 77.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 77.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 77.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 77.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 77.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 76.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 76.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 75.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 74.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 74.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 74.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 73.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 72.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 72.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 71.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 71.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 70.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 70.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 69.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 69.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 69.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 69.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 68.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 68.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 68.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 67.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 67.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 67.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 66.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 66.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 65.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 65.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 64.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 64.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 64.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 63.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 63.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 62.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 62.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 62.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 62.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 61.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 60.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 59.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 59.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 58.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 58.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 58.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 57.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 55.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 55.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 55.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 54.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 53.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 52.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 41.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 40.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 65.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 65.2
FF:10158-103A5 76 years, female 65.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 42.9
Pig sample Sample description nTPM
Midbrain
nTPM: 36.4
Samples: 4

Max nTPM: 57.4
Min nTPM: 24.3
Sample A Female 57.4
Sample B Female 29.0
Sample C Male 35.0
Sample D Male 24.3
Periaqueductal gray
nTPM: 27.6
Samples: 3

Max nTPM: 30.6
Min nTPM: 24.3
Sample B Female 28.0
Sample C Male 30.6
Sample D Male 24.3
Substantia nigra
nTPM: 36.3
Samples: 4

Max nTPM: 43.4
Min nTPM: 30.7
Sample A Female 43.4
Sample B Female 38.8
Sample C Male 32.2
Sample D Male 30.7
Superior colliculi
nTPM: 42.9
Samples: 4

Max nTPM: 61.4
Min nTPM: 30.9
Sample A Female 46.3
Sample B Female 61.4
Sample C Male 32.9
Sample D Male 30.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 112.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 112.9
Samples: 4

Max nTPM: 116.5
Min nTPM: 109.2
Sample A Male 116.5
Sample B Male 109.2
Sample C Female 111.8
Sample D Female 114.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 14.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.9
74658245 Antisense, RP_060220_02_D11, Mouse strain C57BL/6J (56 days, male) 15.6
68443256 Antisense, RP_050111_01_F06, Mouse strain C57BL/6J (56 days, male) 14.3

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