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MT-ND1
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:84925.4 nTPM
HPA:84925.4 nTPM
GTEx:65906.9 nTPM
Pig:13885.9 nTPM
Mouse:12252.4 nTPM
Allen mouse:25.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 84925.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 74804.9
2219 Male, age 76, both hemispheres 83613.2
2586 Male, age 75, left hemisphere 81436.5
2666 Male, age 74, left hemisphere 78309.9
2828 Female, age 72, unknown 76227.6
1870 Female, age 42, unknown 75749.6
1833 Male, age 53, unknown 75423.2
1830 Male, age 51, unknown 74330.2
1827 Male, age 72, unknown 68631.8
2019 Male, age 18, unknown 67485.1
2411 Female, age 72, unknown 66841.7
Dorsal raphe nucleus
nTPM: 68099.8
1828 Male, age 53, unknown 72001.1
2750 Male, age 76, both hemispheres 69899.3
2047 Male, age 72, unknown 68924.0
2016 Female, age 72, unknown 67169.3
2298 Female, age 72, unknown 62505.1
Inferior colliculus
nTPM: 74871.4
2849 Male, age 72, unknown 90170.4
1848 Female, age 42, unknown 73436.9
1890 Male, age 53, unknown 71743.0
2097 Female, age 72, unknown 64135.2
Median raphe nucleus
nTPM: 84925.4
2220 Male, age 76, midline 84925.4
Pedunculopontine tegmental nucleus
nTPM: 73509.0
2334 Male, age 80, both hemispheres 77674.2
2338 Male, age 61, both hemispheres 75801.7
1921 Female, age 85, both hemispheres 67050.9
Periaquaductal grey, anterior
nTPM: 68432.7
2502 Female, age 75, unknown 71402.8
1795 Male, age 51, unknown 67350.2
1947 Male, age 18, unknown 66545.1
Periaquaductal grey, dorsal
nTPM: 71901.7
2850 Male, age 76, both hemispheres 79191.6
2464 Female, age 72, unknown 71165.4
1840 Male, age 53, unknown 68745.5
1831 Male, age 72, unknown 68504.5
Periaquaductal grey, lateral
nTPM: 66775.0
2140 Male, age 76, both hemispheres 69230.6
2053 Male, age 18, unknown 66724.4
2272 Male, age 74, both hemispheres 64369.9
Pretectal area
nTPM: 70461.5
2667 Female, age 75, unknown 76720.6
1944 Female, age 72, unknown 74468.4
2825 Male, age 18, unknown 73535.7
1817 Female, age 42, unknown 73438.4
1816 Male, age 51, unknown 72864.9
1815 Male, age 53, unknown 72791.9
2007 Male, age 72, unknown 71058.3
2407 Male, age 75, both hemispheres 68077.8
2224 Female, age 72, unknown 65706.2
2316 Male, age 76, right hemisphere 63454.3
2273 Male, age 74, both hemispheres 62960.4
Red nucleus
nTPM: 74612.5
2503 Female, age 72, unknown 80675.7
2588 Male, age 74, left hemisphere 78696.0
1954 Female, age 42, unknown 78069.4
1865 Male, age 51, unknown 76474.6
2823 Male, age 76, right hemisphere 76404.4
2584 Male, age 75, left hemisphere 74350.8
2227 Male, age 72, unknown 73945.0
1904 Male, age 53, unknown 73205.0
2785 Male, age 18, unknown 72831.3
2769 Male, age 72, unknown 72434.2
2725 Female, age 75, unknown 70098.7
1821 Female, age 72, unknown 68164.9
Substantia nigra
nTPM: 76142.8
2665 Male, age 74, both hemispheres 96513.9
2699 Male, age 18, unknown 92172.9
1916 Female, age 42, unknown 77140.7
1941 Male, age 53, unknown 73899.6
2241 Male, age 72, unknown 72083.4
1889 Female, age 72, unknown 71139.4
2583 Male, age 75, right hemisphere 70789.7
2409 Female, age 72, unknown 70145.6
1851 Male, age 51, unknown 69883.7
2590 Female, age 75, unknown 67659.4
Superior colliculus
nTPM: 70989.8
2664 Male, age 75, both hemispheres 78077.0
2087 Female, age 72, unknown 72533.0
2587 Male, age 74, left hemisphere 71839.3
2668 Female, age 75, unknown 71155.2
1839 Male, age 51, unknown 70348.1
1913 Female, age 42, unknown 70299.7
1895 Male, age 76, right hemisphere 69927.9
1796 Male, age 53, unknown 69694.9
1995 Male, age 72, unknown 68334.4
2261 Male, age 18, unknown 67688.3
Ventral tegmental area
nTPM: 73972.2
2218 Male, age 76, both hemispheres 84978.2
2223 Female, age 72, unknown 77292.0
1942 Male, age 51, unknown 72896.5
2410 Female, age 72, unknown 70309.6
1915 Female, age 42, unknown 70054.6
2021 Male, age 53, unknown 68302.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 65906.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 65906.9
Samples: 139

Max nTPM: 254934.5
Min nTPM: 11766.7
Std nTPM: 44229.1
Median nTPM: 53854.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 254934.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 218902.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 181629.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 177912.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 169419.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 167816.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 157266.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 153245.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 147717.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 147707.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 145882.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 145382.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 140302.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 136775.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 135874.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 126445.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 124127.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 120158.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 120008.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 112379.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 112148.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 111632.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 107418.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 100323.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 99513.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 98360.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 90488.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 87013.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 86954.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 85373.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 85238.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 84669.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 83278.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 83252.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 82294.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 80512.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 80003.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 77267.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 76991.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 76191.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 75603.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 75130.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 74690.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 74027.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 71210.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 71171.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 71164.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 70225.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 69361.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 69308.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 68630.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 68621.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 67680.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 66876.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 66161.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 64840.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 63914.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 63595.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 63322.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 61960.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 61451.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 61450.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 61084.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 58667.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 58091.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 57179.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 56739.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 55716.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 54816.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 53854.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 52122.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 51448.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 51033.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 50658.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 50471.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 50335.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 49525.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 49309.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 48130.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 46433.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 46389.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 46066.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 45480.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 44398.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 44197.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 43895.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 43814.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 41007.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 39268.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 39145.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 39056.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 38255.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 37851.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 37700.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 36709.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 36658.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 36068.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 35575.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 35131.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 34975.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 34740.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 34460.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 34204.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 33750.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 33174.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 33041.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 32311.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 32082.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 31490.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 31103.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 30468.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 29829.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 29323.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 28927.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 28833.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 28605.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 28100.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 28020.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 27647.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 27227.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 27059.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 27059.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 26487.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 26295.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 25991.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 25929.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 25872.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 23429.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 23415.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 22949.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 22279.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 21467.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 20784.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 20413.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 17528.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 17003.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 15323.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 12181.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 11766.7
Show allShow less

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 13885.9
Pig sample Sample description nTPM
Midbrain
nTPM: 13885.9
Samples: 4

Max nTPM: 19506.7
Min nTPM: 8955.2
Sample A Female 13047.8
Sample B Female 19506.7
Sample C Male 14034.0
Sample D Male 8955.2
Periaqueductal gray
nTPM: 10671.1
Samples: 3

Max nTPM: 11387.3
Min nTPM: 9275.8
Sample B Female 11350.1
Sample C Male 11387.3
Sample D Male 9275.8
Substantia nigra
nTPM: 11180.3
Samples: 4

Max nTPM: 14745.3
Min nTPM: 6889.5
Sample A Female 14745.3
Sample B Female 10011.5
Sample C Male 13075.0
Sample D Male 6889.5
Superior colliculi
nTPM: 10916.0
Samples: 4

Max nTPM: 14790.2
Min nTPM: 2052.8
Sample A Female 13145.7
Sample B Female 2052.8
Sample C Male 14790.2
Sample D Male 13675.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 12252.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 12252.4
Samples: 4

Max nTPM: 12793.7
Min nTPM: 11886.7
Sample A Male 12275.8
Sample B Male 12053.3
Sample C Female 12793.7
Sample D Female 11886.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 25.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 25.1
74357749 Antisense, RP_051219_04_A03, Mouse strain C57BL/6J (56 days, male) 25.1

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