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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:510.0 nTPM
HPA:510.0 nTPM
GTEx:478.4 nTPM
FANTOM5:75.5 Scaled Tags Per Million
Pig:131.4 nTPM
Mouse:115.4 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 510.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 487.2
1870 Female, age 42, unknown 505.4
1833 Male, age 53, unknown 492.3
1830 Male, age 51, unknown 490.0
2219 Male, age 76, both hemispheres 489.3
2411 Female, age 72, unknown 487.8
1827 Male, age 72, unknown 487.5
2666 Male, age 74, left hemisphere 484.5
2019 Male, age 18, unknown 482.9
2828 Female, age 72, unknown 482.0
2586 Male, age 75, left hemisphere 470.8
Dorsal raphe nucleus
nTPM: 492.9
2750 Male, age 76, both hemispheres 497.7
2016 Female, age 72, unknown 493.2
2047 Male, age 72, unknown 492.2
1828 Male, age 53, unknown 491.5
2298 Female, age 72, unknown 489.9
Inferior colliculus
nTPM: 499.1
2849 Male, age 72, unknown 505.3
2097 Female, age 72, unknown 500.2
1848 Female, age 42, unknown 497.4
1890 Male, age 53, unknown 493.3
Median raphe nucleus
nTPM: 500.6
2220 Male, age 76, midline 500.6
Pedunculopontine tegmental nucleus
nTPM: 510.0
2338 Male, age 61, both hemispheres 517.2
2334 Male, age 80, both hemispheres 510.1
1921 Female, age 85, both hemispheres 502.7
Periaquaductal grey, anterior
nTPM: 489.6
1947 Male, age 18, unknown 491.6
2502 Female, age 75, unknown 491.1
1795 Male, age 51, unknown 485.9
Periaquaductal grey, dorsal
nTPM: 495.5
2850 Male, age 76, both hemispheres 506.5
1840 Male, age 53, unknown 500.7
1831 Male, age 72, unknown 488.6
2464 Female, age 72, unknown 486.1
Periaquaductal grey, lateral
nTPM: 489.1
2053 Male, age 18, unknown 493.6
2140 Male, age 76, both hemispheres 493.3
2272 Male, age 74, both hemispheres 480.3
Pretectal area
nTPM: 493.5
2224 Female, age 72, unknown 502.3
2667 Female, age 75, unknown 501.8
1817 Female, age 42, unknown 497.0
2407 Male, age 75, both hemispheres 496.6
2825 Male, age 18, unknown 496.0
1944 Female, age 72, unknown 493.4
1815 Male, age 53, unknown 490.7
1816 Male, age 51, unknown 490.2
2273 Male, age 74, both hemispheres 487.7
2007 Male, age 72, unknown 487.3
2316 Male, age 76, right hemisphere 485.2
Red nucleus
nTPM: 494.7
1821 Female, age 72, unknown 504.8
2725 Female, age 75, unknown 503.6
1865 Male, age 51, unknown 500.8
2227 Male, age 72, unknown 498.9
2503 Female, age 72, unknown 498.4
1954 Female, age 42, unknown 498.2
1904 Male, age 53, unknown 494.6
2769 Male, age 72, unknown 494.4
2823 Male, age 76, right hemisphere 492.0
2584 Male, age 75, left hemisphere 485.4
2588 Male, age 74, left hemisphere 483.4
2785 Male, age 18, unknown 481.7
Substantia nigra
nTPM: 495.3
2699 Male, age 18, unknown 510.6
2665 Male, age 74, both hemispheres 502.7
1889 Female, age 72, unknown 502.5
1916 Female, age 42, unknown 502.2
1851 Male, age 51, unknown 495.9
1941 Male, age 53, unknown 494.9
2241 Male, age 72, unknown 494.8
2590 Female, age 75, unknown 486.5
2409 Female, age 72, unknown 482.0
2583 Male, age 75, right hemisphere 480.9
Superior colliculus
nTPM: 490.7
1895 Male, age 76, right hemisphere 503.1
2587 Male, age 74, left hemisphere 500.3
1913 Female, age 42, unknown 495.2
1839 Male, age 51, unknown 492.8
1995 Male, age 72, unknown 492.4
1796 Male, age 53, unknown 488.0
2087 Female, age 72, unknown 485.2
2261 Male, age 18, unknown 484.9
2664 Male, age 75, both hemispheres 483.7
2668 Female, age 75, unknown 481.6
Ventral tegmental area
nTPM: 495.6
2223 Female, age 72, unknown 504.8
1915 Female, age 42, unknown 500.9
2021 Male, age 53, unknown 495.3
2218 Male, age 76, both hemispheres 494.4
2410 Female, age 72, unknown 489.3
1942 Male, age 51, unknown 488.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 478.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 478.4
Samples: 139

Max nTPM: 1019.1
Min nTPM: 264.3
Std nTPM: 129.6
Median nTPM: 459.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1019.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 919.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 898.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 825.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 795.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 751.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 727.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 709.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 674.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 630.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 628.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 628.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 626.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 625.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 622.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 620.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 611.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 599.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 597.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 595.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 590.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 585.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 580.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 579.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 573.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 571.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 571.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 570.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 566.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 565.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 555.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 555.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 553.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 552.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 551.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 549.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 535.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 534.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 533.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 531.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 531.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 522.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 517.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 515.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 513.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 513.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 511.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 511.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 507.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 506.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 505.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 500.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 498.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 498.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 497.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 495.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 489.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 487.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 487.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 486.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 486.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 481.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 479.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 478.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 475.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 474.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 472.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 469.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 462.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 459.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 457.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 452.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 449.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 448.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 447.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 446.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 446.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 445.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 443.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 442.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 440.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 440.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 439.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 438.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 437.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 435.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 433.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 430.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 427.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 424.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 424.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 422.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 422.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 418.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 417.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 416.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 414.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 410.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 408.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 406.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 399.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 394.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 392.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 389.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 388.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 388.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 385.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 381.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 378.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 377.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 376.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 374.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 372.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 365.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 362.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 361.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 357.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 352.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 351.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 349.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 349.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 348.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 345.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 343.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 340.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 331.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 324.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 323.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 320.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 320.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 289.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 287.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 285.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 284.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 281.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 274.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 272.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 266.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 264.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 75.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 75.5
FF:10158-103A5 76 years, female 75.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 131.4
Pig sample Sample description nTPM
Midbrain
nTPM: 118.2
Samples: 4

Max nTPM: 132.8
Min nTPM: 105.1
Sample A Female 132.8
Sample B Female 126.1
Sample C Male 105.1
Sample D Male 108.7
Periaqueductal gray
nTPM: 115.7
Samples: 3

Max nTPM: 128.1
Min nTPM: 107.0
Sample B Female 107.0
Sample C Male 128.1
Sample D Male 112.1
Substantia nigra
nTPM: 131.4
Samples: 4

Max nTPM: 168.4
Min nTPM: 97.7
Sample A Female 168.4
Sample B Female 132.7
Sample C Male 126.7
Sample D Male 97.7
Superior colliculi
nTPM: 123.6
Samples: 4

Max nTPM: 162.1
Min nTPM: 92.9
Sample A Female 162.1
Sample B Female 92.9
Sample C Male 132.5
Sample D Male 106.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 115.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 115.4
Samples: 4

Max nTPM: 126.0
Min nTPM: 98.9
Sample A Male 126.0
Sample B Male 117.6
Sample C Female 98.9
Sample D Female 119.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
71763951 Antisense, RP_050921_02_H07, Mouse strain C57BL/6J (56 days, male) 0.1

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