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C4orf48
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:63.2 nTPM
HPA:63.2 nTPM
GTEx:117.3 nTPM
FANTOM5:86.0 Scaled Tags Per Million
Pig:21.6 nTPM
Mouse:2.4 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 63.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 54.1
2586 Male, age 75, left hemisphere 88.0
2411 Female, age 72, unknown 61.5
2019 Male, age 18, unknown 56.3
1870 Female, age 42, unknown 55.4
2828 Female, age 72, unknown 53.6
1830 Male, age 51, unknown 52.1
1833 Male, age 53, unknown 44.4
1827 Male, age 72, unknown 44.1
2666 Male, age 74, left hemisphere 43.9
2219 Male, age 76, both hemispheres 41.8
Dorsal raphe nucleus
nTPM: 51.4
2750 Male, age 76, both hemispheres 67.5
2047 Male, age 72, unknown 50.7
2016 Female, age 72, unknown 48.4
1828 Male, age 53, unknown 46.9
2298 Female, age 72, unknown 43.6
Inferior colliculus
nTPM: 34.4
1890 Male, age 53, unknown 38.5
1848 Female, age 42, unknown 35.3
2097 Female, age 72, unknown 32.9
2849 Male, age 72, unknown 30.8
Median raphe nucleus
nTPM: 50.9
2220 Male, age 76, midline 50.9
Pedunculopontine tegmental nucleus
nTPM: 39.4
2334 Male, age 80, both hemispheres 47.5
1921 Female, age 85, both hemispheres 42.7
2338 Male, age 61, both hemispheres 28.0
Periaquaductal grey, anterior
nTPM: 63.2
1795 Male, age 51, unknown 66.2
1947 Male, age 18, unknown 64.1
2502 Female, age 75, unknown 59.4
Periaquaductal grey, dorsal
nTPM: 30.7
1831 Male, age 72, unknown 33.9
2464 Female, age 72, unknown 31.4
1840 Male, age 53, unknown 30.5
2850 Male, age 76, both hemispheres 26.8
Periaquaductal grey, lateral
nTPM: 42.1
2272 Male, age 74, both hemispheres 59.7
2053 Male, age 18, unknown 37.2
2140 Male, age 76, both hemispheres 29.5
Pretectal area
nTPM: 48.3
2007 Male, age 72, unknown 60.7
2224 Female, age 72, unknown 54.5
2273 Male, age 74, both hemispheres 51.5
1817 Female, age 42, unknown 50.2
1815 Male, age 53, unknown 47.8
2667 Female, age 75, unknown 47.5
2407 Male, age 75, both hemispheres 46.2
1816 Male, age 51, unknown 45.0
2825 Male, age 18, unknown 44.0
1944 Female, age 72, unknown 42.9
2316 Male, age 76, right hemisphere 41.4
Red nucleus
nTPM: 59.6
2503 Female, age 72, unknown 79.9
2785 Male, age 18, unknown 74.3
2227 Male, age 72, unknown 68.9
2588 Male, age 74, left hemisphere 64.9
2769 Male, age 72, unknown 64.7
1904 Male, age 53, unknown 61.4
1954 Female, age 42, unknown 58.0
1865 Male, age 51, unknown 57.1
1821 Female, age 72, unknown 51.2
2584 Male, age 75, left hemisphere 49.4
2725 Female, age 75, unknown 44.7
2823 Male, age 76, right hemisphere 40.1
Substantia nigra
nTPM: 46.2
2583 Male, age 75, right hemisphere 65.9
1916 Female, age 42, unknown 56.2
1851 Male, age 51, unknown 53.9
1889 Female, age 72, unknown 50.7
1941 Male, age 53, unknown 49.1
2590 Female, age 75, unknown 45.9
2665 Male, age 74, both hemispheres 41.3
2409 Female, age 72, unknown 36.5
2699 Male, age 18, unknown 36.2
2241 Male, age 72, unknown 26.8
Superior colliculus
nTPM: 50.1
2668 Female, age 75, unknown 67.6
1995 Male, age 72, unknown 57.7
2587 Male, age 74, left hemisphere 57.0
2664 Male, age 75, both hemispheres 55.5
1913 Female, age 42, unknown 54.4
2261 Male, age 18, unknown 52.0
1796 Male, age 53, unknown 51.9
1839 Male, age 51, unknown 46.2
1895 Male, age 76, right hemisphere 31.9
2087 Female, age 72, unknown 27.1
Ventral tegmental area
nTPM: 53.2
2223 Female, age 72, unknown 61.5
2410 Female, age 72, unknown 52.4
1915 Female, age 42, unknown 51.9
2218 Male, age 76, both hemispheres 51.7
2021 Male, age 53, unknown 51.5
1942 Male, age 51, unknown 50.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 117.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 117.3
Samples: 139

Max nTPM: 558.5
Min nTPM: 13.7
Std nTPM: 79.9
Median nTPM: 103.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 558.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 489.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 424.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 334.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 319.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 239.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 229.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 228.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 226.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 224.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 224.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 212.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 209.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 206.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 195.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 190.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 188.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 184.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 183.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 183.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 177.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 175.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 174.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 173.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 159.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 158.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 152.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 152.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 149.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 146.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 146.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 146.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 144.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 142.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 141.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 141.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 139.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 139.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 131.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 129.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 129.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 129.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 129.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 128.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 127.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 123.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 123.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 120.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 120.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 116.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 115.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 115.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 113.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 113.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 113.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 112.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 111.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 110.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 110.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 109.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 109.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 108.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 107.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 107.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 107.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 105.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 103.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 103.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 103.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 103.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 102.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 102.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 102.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 102.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 99.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 99.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 97.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 94.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 94.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 93.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 93.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 93.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 91.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 91.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 90.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 88.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 88.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 87.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 86.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 83.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 81.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 80.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 78.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 78.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 77.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 76.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 76.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 73.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 70.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 70.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 69.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 67.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 66.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 66.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 66.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 66.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 62.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 62.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 62.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 62.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 61.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 60.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 59.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 58.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 56.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 52.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 52.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 51.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 51.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 51.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 51.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 49.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 49.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 49.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 48.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 46.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 46.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 44.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 43.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 41.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 41.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 39.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 39.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 33.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 29.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 26.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 23.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 13.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 13.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 86.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 86.0
FF:10158-103A5 76 years, female 86.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 21.6
Pig sample Sample description nTPM
Midbrain
nTPM: 21.5
Samples: 4

Max nTPM: 24.4
Min nTPM: 19.5
Sample A Female 24.4
Sample B Female 19.5
Sample C Male 21.7
Sample D Male 20.4
Periaqueductal gray
nTPM: 21.6
Samples: 3

Max nTPM: 23.9
Min nTPM: 19.8
Sample B Female 21.1
Sample C Male 23.9
Sample D Male 19.8
Substantia nigra
nTPM: 20.0
Samples: 4

Max nTPM: 37.6
Min nTPM: 8.1
Sample A Female 37.6
Sample B Female 15.5
Sample C Male 18.9
Sample D Male 8.1
Superior colliculi
nTPM: 20.0
Samples: 4

Max nTPM: 33.3
Min nTPM: 12.4
Sample A Female 33.3
Sample B Female 12.4
Sample C Male 17.3
Sample D Male 17.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 2.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 2.4
Samples: 4

Max nTPM: 3.8
Min nTPM: 1.6
Sample A Male 3.8
Sample B Male 1.8
Sample C Female 2.5
Sample D Female 1.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
74581181 Antisense, RP_060215_02_G02, Mouse strain C57BL/6J (56 days, male) 0.2

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