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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 351.2
Min nTPM: 90.9
Std nTPM: 41.1
Median nTPM: 158.6
GTEX-QDVN-1626-SM-48TZC
50-59 years, male
351.2
GTEX-ZLFU-0926-SM-5P9F8
40-49 years, male
304.7
GTEX-1JMQK-1926-SM-CJI3B
60-69 years, male
278.3
GTEX-145MN-0326-SM-5QGQI
30-39 years, male
247.4
GTEX-1GN1U-2126-SM-AHZ4J
50-59 years, female
230.6
GTEX-QLQW-1626-SM-CMKFE
30-39 years, male
229.6
GTEX-ZVZP-0926-SM-5GIDB
50-59 years, male
221.7
GTEX-1E2YA-1626-SM-7MGXS
50-59 years, male
221.0
GTEX-1399S-0526-SM-5IJG8
30-39 years, female
216.5
GTEX-Y5V5-1226-SM-EYYVP
60-69 years, female
215.1
GTEX-Y5V6-2026-SM-5IFHO
60-69 years, male
212.8
GTEX-1MUQO-2526-SM-E9TJN
60-69 years, male
208.6
GTEX-XPVG-0526-SM-4B65N
50-59 years, male
208.0
GTEX-1A3MW-2226-SM-73KUX
60-69 years, female
201.3
GTEX-1PWST-2226-SM-EVR3G
70-79 years, male
193.9
GTEX-17F97-1926-SM-7IGM4
50-59 years, male
193.4
GTEX-ZYFG-1626-SM-5GZYY
60-69 years, female
192.9
GTEX-12WSG-0826-SM-5EQ5A
50-59 years, female
188.9
GTEX-ZYT6-2226-SM-5GIC9
30-39 years, male
185.8
GTEX-13OVI-1126-SM-5KLZF
60-69 years, female
184.5
GTEX-1CB4J-1926-SM-7MGX8
60-69 years, male
184.0
GTEX-ZDXO-0226-SM-4WKH7
60-69 years, male
183.8
GTEX-15CHQ-2126-SM-6871M
60-69 years, male
180.9
GTEX-17F96-1926-SM-7MGWY
70-79 years, male
180.7
GTEX-1JMLX-1526-SM-AHZ3N
50-59 years, male
179.5
GTEX-1BAJH-1826-SM-731DA
70-79 years, male
179.0
GTEX-1C6VQ-2326-SM-7IGN1
50-59 years, male
172.2
GTEX-ZC5H-1726-SM-5HL7X
40-49 years, female
171.5
GTEX-QDT8-1726-SM-EYYV6
30-39 years, female
171.3
GTEX-13O1R-2526-SM-5N9FW
60-69 years, male
169.2
GTEX-1QP6S-1526-SM-EXUSG
40-49 years, male
167.8
GTEX-1H3VY-1926-SM-9JGHJ
50-59 years, male
167.3
GTEX-16MT8-1926-SM-7EPGL
60-69 years, female
165.1
GTEX-1N2DW-1826-SM-EAZ54
50-59 years, male
164.3
GTEX-ZE9C-1426-SM-4WKGM
60-69 years, male
163.5
GTEX-11GS4-2326-SM-5A5KS
60-69 years, male
163.0
GTEX-1H3NZ-2126-SM-9WPQ6
60-69 years, male
162.6
GTEX-1J1OQ-1426-SM-AHZ3P
40-49 years, female
162.0
GTEX-1HBPI-2026-SM-CE6RZ
50-59 years, male
160.8
GTEX-T5JC-1526-SM-4DM68
20-29 years, male
159.5
GTEX-13OW6-1826-SM-5N9F9
50-59 years, male
158.9
GTEX-13RTJ-2226-SM-5S2Q1
60-69 years, male
158.7
GTEX-11TTK-1926-SM-5PNW8
60-69 years, female
158.6
GTEX-12696-0926-SM-5FQTV
60-69 years, male
156.4
GTEX-1NV8Z-2226-SM-EXOJ2
60-69 years, male
155.9
GTEX-1JMPZ-1226-SM-ARU8Y
30-39 years, male
155.7
GTEX-11OF3-1326-SM-5N9FJ
60-69 years, male
154.7
GTEX-13112-2126-SM-5GCO4
50-59 years, male
153.7
GTEX-1AX8Z-2326-SM-731CR
60-69 years, male
153.6
GTEX-1IL2V-1826-SM-ARU7R
70-79 years, male
153.2
GTEX-REY6-1826-SM-EAZAT
60-69 years, male
152.7
GTEX-1GTWX-1826-SM-9QEHG
60-69 years, male
152.6
GTEX-T6MN-1826-SM-EXOHN
50-59 years, male
152.5
GTEX-1EKGG-2226-SM-7IGOA
60-69 years, male
151.8
GTEX-15DYW-2026-SM-6AJBD
60-69 years, female
150.9
GTEX-1HCU7-1826-SM-A9G2A
50-59 years, male
150.5
GTEX-1497J-0826-SM-5NQAJ
60-69 years, male
150.4
GTEX-14C5O-2026-SM-5YYB1
60-69 years, male
147.9
GTEX-RN64-1626-SM-48FD7
50-59 years, male
147.4
GTEX-P4QS-1126-SM-3NMD5
60-69 years, male
146.8
GTEX-1HB9E-1826-SM-D4P33
50-59 years, male
146.3
GTEX-S33H-1426-SM-EZ6L7
30-39 years, male
146.3
GTEX-1A8FM-2026-SM-7P8RN
50-59 years, female
143.3
GTEX-O5YV-1226-SM-EV795
60-69 years, female
143.1
GTEX-1F48J-2226-SM-7MXTN
50-59 years, female
143.0
GTEX-147F4-2626-SM-5Q5CS
50-59 years, male
142.7
GTEX-1KWVE-0826-SM-CXZKO
30-39 years, male
141.0
GTEX-1GMR3-2426-SM-7MXV2
40-49 years, male
140.8
GTEX-1GF9W-1326-SM-7P8PX
60-69 years, male
140.1
GTEX-17HHY-2326-SM-7KFSR
50-59 years, male
138.9
GTEX-1GF9V-1926-SM-9JGHE
60-69 years, male
138.9
GTEX-1K9T9-1826-SM-CXZK2
50-59 years, female
137.0
GTEX-1JJ6O-2526-SM-AHZ3J
60-69 years, male
136.7
GTEX-13NYB-1726-SM-5N9G2
40-49 years, male
136.6
GTEX-14C39-2126-SM-664OH
40-49 years, male
136.0
GTEX-1OJC4-2326-SM-DTXA5
50-59 years, female
134.0
GTEX-NPJ8-2226-SM-3TW8D
40-49 years, male
133.5
GTEX-1R9PO-1626-SM-E6CPT
60-69 years, female
126.0
GTEX-13OVL-1826-SM-5KLZR
50-59 years, male
124.9
GTEX-1I1GP-1926-SM-CNNQU
50-59 years, male
124.4
GTEX-1N2EF-1426-SM-EXUSH
60-69 years, male
113.6
GTEX-1IKK5-0926-SM-A9G2U
60-69 years, male
108.6
GTEX-14E6D-2526-SM-5YYA9
50-59 years, male
105.1
GTEX-1JMQJ-1726-SM-E9U4V
50-59 years, male
103.0
GTEX-1LG7Y-2726-SM-D5OVW
50-59 years, male
90.9
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Kidney - Medulla Average nTPM: 136.0
Samples: 4
Max nTPM: 161.6
Min nTPM: 107.5
Std nTPM: 19.5
Median nTPM: 137.5
GTEX-TKQ2-0626-SM-EZ6LB
50-59 years, male
161.6
GTEX-RU72-1926-SM-EAZ3F
50-59 years, female
142.8
GTEX-R55E-2026-SM-EZ6L1
20-29 years, male
132.3
GTEX-T5JC-1626-SM-EZ6KW
20-29 years, male
107.5
KIDNEY - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.