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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 0.5
Min nTPM: 0.0
Std nTPM: 0.1
Median nTPM: 0.1
GTEX-11TTK-1926-SM-5PNW8
60-69 years, female
0.5
GTEX-13112-2126-SM-5GCO4
50-59 years, male
0.4
GTEX-13OVI-1126-SM-5KLZF
60-69 years, female
0.4
GTEX-147F4-2626-SM-5Q5CS
50-59 years, male
0.4
GTEX-RN64-1626-SM-48FD7
50-59 years, male
0.4
GTEX-ZLFU-0926-SM-5P9F8
40-49 years, male
0.4
GTEX-ZVZP-0926-SM-5GIDB
50-59 years, male
0.4
GTEX-ZYFG-1626-SM-5GZYY
60-69 years, female
0.4
GTEX-T5JC-1526-SM-4DM68
20-29 years, male
0.3
GTEX-Y5V6-2026-SM-5IFHO
60-69 years, male
0.3
GTEX-ZDXO-0226-SM-4WKH7
60-69 years, male
0.3
GTEX-1F48J-2226-SM-7MXTN
50-59 years, female
0.3
GTEX-1GMR3-2426-SM-7MXV2
40-49 years, male
0.3
GTEX-1H3VY-1926-SM-9JGHJ
50-59 years, male
0.3
GTEX-1JMLX-1526-SM-AHZ3N
50-59 years, male
0.3
GTEX-1N2DW-1826-SM-EAZ54
50-59 years, male
0.3
GTEX-O5YV-1226-SM-EV795
60-69 years, female
0.3
GTEX-17F97-1926-SM-7IGM4
50-59 years, male
0.2
GTEX-1E2YA-1626-SM-7MGXS
50-59 years, male
0.2
GTEX-1GN1U-2126-SM-AHZ4J
50-59 years, female
0.2
GTEX-1H3NZ-2126-SM-9WPQ6
60-69 years, male
0.2
GTEX-1LG7Y-2726-SM-D5OVW
50-59 years, male
0.2
GTEX-1OJC4-2326-SM-DTXA5
50-59 years, female
0.2
GTEX-11GS4-2326-SM-5A5KS
60-69 years, male
0.1
GTEX-11OF3-1326-SM-5N9FJ
60-69 years, male
0.1
GTEX-1399S-0526-SM-5IJG8
30-39 years, female
0.1
GTEX-13RTJ-2226-SM-5S2Q1
60-69 years, male
0.1
GTEX-14C39-2126-SM-664OH
40-49 years, male
0.1
GTEX-14C5O-2026-SM-5YYB1
60-69 years, male
0.1
GTEX-15DYW-2026-SM-6AJBD
60-69 years, female
0.1
GTEX-1AX8Z-2326-SM-731CR
60-69 years, male
0.1
GTEX-QDVN-1626-SM-48TZC
50-59 years, male
0.1
GTEX-XPVG-0526-SM-4B65N
50-59 years, male
0.1
GTEX-ZE9C-1426-SM-4WKGM
60-69 years, male
0.1
GTEX-ZYT6-2226-SM-5GIC9
30-39 years, male
0.1
GTEX-1A8FM-2026-SM-7P8RN
50-59 years, female
0.1
GTEX-1HB9E-1826-SM-D4P33
50-59 years, male
0.1
GTEX-1IL2V-1826-SM-ARU7R
70-79 years, male
0.1
GTEX-1J1OQ-1426-SM-AHZ3P
40-49 years, female
0.1
GTEX-1JMQK-1926-SM-CJI3B
60-69 years, male
0.1
GTEX-1K9T9-1826-SM-CXZK2
50-59 years, female
0.1
GTEX-1MUQO-2526-SM-E9TJN
60-69 years, male
0.1
GTEX-1PWST-2226-SM-EVR3G
70-79 years, male
0.1
GTEX-1R9PO-1626-SM-E6CPT
60-69 years, female
0.1
GTEX-12696-0926-SM-5FQTV
60-69 years, male
0.0
GTEX-12WSG-0826-SM-5EQ5A
50-59 years, female
0.0
GTEX-13NYB-1726-SM-5N9G2
40-49 years, male
0.0
GTEX-13O1R-2526-SM-5N9FW
60-69 years, male
0.0
GTEX-13OVL-1826-SM-5KLZR
50-59 years, male
0.0
GTEX-13OW6-1826-SM-5N9F9
50-59 years, male
0.0
GTEX-145MN-0326-SM-5QGQI
30-39 years, male
0.0
GTEX-1497J-0826-SM-5NQAJ
60-69 years, male
0.0
GTEX-14E6D-2526-SM-5YYA9
50-59 years, male
0.0
GTEX-15CHQ-2126-SM-6871M
60-69 years, male
0.0
GTEX-16MT8-1926-SM-7EPGL
60-69 years, female
0.0
GTEX-17HHY-2326-SM-7KFSR
50-59 years, male
0.0
GTEX-1A3MW-2226-SM-73KUX
60-69 years, female
0.0
GTEX-1BAJH-1826-SM-731DA
70-79 years, male
0.0
GTEX-1C6VQ-2326-SM-7IGN1
50-59 years, male
0.0
GTEX-1EKGG-2226-SM-7IGOA
60-69 years, male
0.0
GTEX-NPJ8-2226-SM-3TW8D
40-49 years, male
0.0
GTEX-P4QS-1126-SM-3NMD5
60-69 years, male
0.0
GTEX-ZC5H-1726-SM-5HL7X
40-49 years, female
0.0
GTEX-17F96-1926-SM-7MGWY
70-79 years, male
0.0
GTEX-1CB4J-1926-SM-7MGX8
60-69 years, male
0.0
GTEX-1GF9V-1926-SM-9JGHE
60-69 years, male
0.0
GTEX-1GF9W-1326-SM-7P8PX
60-69 years, male
0.0
GTEX-1GTWX-1826-SM-9QEHG
60-69 years, male
0.0
GTEX-1HBPI-2026-SM-CE6RZ
50-59 years, male
0.0
GTEX-1HCU7-1826-SM-A9G2A
50-59 years, male
0.0
GTEX-1I1GP-1926-SM-CNNQU
50-59 years, male
0.0
GTEX-1IKK5-0926-SM-A9G2U
60-69 years, male
0.0
GTEX-1JJ6O-2526-SM-AHZ3J
60-69 years, male
0.0
GTEX-1JMPZ-1226-SM-ARU8Y
30-39 years, male
0.0
GTEX-1JMQJ-1726-SM-E9U4V
50-59 years, male
0.0
GTEX-1KWVE-0826-SM-CXZKO
30-39 years, male
0.0
GTEX-1N2EF-1426-SM-EXUSH
60-69 years, male
0.0
GTEX-1NV8Z-2226-SM-EXOJ2
60-69 years, male
0.0
GTEX-1QP6S-1526-SM-EXUSG
40-49 years, male
0.0
GTEX-QDT8-1726-SM-EYYV6
30-39 years, female
0.0
GTEX-QLQW-1626-SM-CMKFE
30-39 years, male
0.0
GTEX-REY6-1826-SM-EAZAT
60-69 years, male
0.0
GTEX-S33H-1426-SM-EZ6L7
30-39 years, male
0.0
GTEX-T6MN-1826-SM-EXOHN
50-59 years, male
0.0
GTEX-Y5V5-1226-SM-EYYVP
60-69 years, female
0.0
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Kidney - Medulla Average nTPM: 0.1
Samples: 4
Max nTPM: 0.2
Min nTPM: 0.0
Std nTPM: 0.0
Median nTPM: 0.2
GTEX-R55E-2026-SM-EZ6L1
20-29 years, male
0.2
GTEX-TKQ2-0626-SM-EZ6LB
50-59 years, male
0.2
GTEX-T5JC-1626-SM-EZ6KW
20-29 years, male
0.1
GTEX-RU72-1926-SM-EAZ3F
50-59 years, female
0.0
KIDNEY - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.