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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 39.2
Min nTPM: 12.0
Std nTPM: 5.7
Median nTPM: 23.2
GTEX-1OJC4-2326-SM-DTXA5
50-59 years, female
39.2
GTEX-13112-2126-SM-5GCO4
50-59 years, male
38.8
GTEX-T5JC-1526-SM-4DM68
20-29 years, male
34.2
GTEX-S33H-1426-SM-EZ6L7
30-39 years, male
34.1
GTEX-NPJ8-2226-SM-3TW8D
40-49 years, male
33.6
GTEX-RN64-1626-SM-48FD7
50-59 years, male
31.5
GTEX-ZYT6-2226-SM-5GIC9
30-39 years, male
31.4
GTEX-O5YV-1226-SM-EV795
60-69 years, female
31.1
GTEX-ZDXO-0226-SM-4WKH7
60-69 years, male
30.6
GTEX-17HHY-2326-SM-7KFSR
50-59 years, male
30.2
GTEX-ZE9C-1426-SM-4WKGM
60-69 years, male
30.0
GTEX-1BAJH-1826-SM-731DA
70-79 years, male
28.8
GTEX-13OVL-1826-SM-5KLZR
50-59 years, male
28.5
GTEX-1QP6S-1526-SM-EXUSG
40-49 years, male
28.5
GTEX-1E2YA-1626-SM-7MGXS
50-59 years, male
28.4
GTEX-15DYW-2026-SM-6AJBD
60-69 years, female
27.4
GTEX-1HBPI-2026-SM-CE6RZ
50-59 years, male
27.3
GTEX-13NYB-1726-SM-5N9G2
40-49 years, male
27.2
GTEX-13RTJ-2226-SM-5S2Q1
60-69 years, male
27.0
GTEX-1H3VY-1926-SM-9JGHJ
50-59 years, male
26.7
GTEX-15CHQ-2126-SM-6871M
60-69 years, male
26.6
GTEX-1HCU7-1826-SM-A9G2A
50-59 years, male
26.6
GTEX-1GN1U-2126-SM-AHZ4J
50-59 years, female
26.0
GTEX-11OF3-1326-SM-5N9FJ
60-69 years, male
25.9
GTEX-ZC5H-1726-SM-5HL7X
40-49 years, female
25.6
GTEX-13OW6-1826-SM-5N9F9
50-59 years, male
25.5
GTEX-T6MN-1826-SM-EXOHN
50-59 years, male
25.2
GTEX-14E6D-2526-SM-5YYA9
50-59 years, male
24.6
GTEX-1399S-0526-SM-5IJG8
30-39 years, female
24.4
GTEX-1JMQJ-1726-SM-E9U4V
50-59 years, male
24.4
GTEX-1NV8Z-2226-SM-EXOJ2
60-69 years, male
24.4
GTEX-Y5V5-1226-SM-EYYVP
60-69 years, female
24.4
GTEX-17F97-1926-SM-7IGM4
50-59 years, male
24.3
GTEX-12WSG-0826-SM-5EQ5A
50-59 years, female
23.8
GTEX-1GF9V-1926-SM-9JGHE
60-69 years, male
23.8
GTEX-1IKK5-0926-SM-A9G2U
60-69 years, male
23.8
GTEX-1JMLX-1526-SM-AHZ3N
50-59 years, male
23.8
GTEX-16MT8-1926-SM-7EPGL
60-69 years, female
23.7
GTEX-17F96-1926-SM-7MGWY
70-79 years, male
23.6
GTEX-1CB4J-1926-SM-7MGX8
60-69 years, male
23.5
GTEX-ZLFU-0926-SM-5P9F8
40-49 years, male
23.4
GTEX-1J1OQ-1426-SM-AHZ3P
40-49 years, female
23.3
GTEX-QDT8-1726-SM-EYYV6
30-39 years, female
23.2
GTEX-14C39-2126-SM-664OH
40-49 years, male
23.1
GTEX-1N2DW-1826-SM-EAZ54
50-59 years, male
22.9
GTEX-1GMR3-2426-SM-7MXV2
40-49 years, male
22.6
GTEX-1KWVE-0826-SM-CXZKO
30-39 years, male
22.2
GTEX-1GTWX-1826-SM-9QEHG
60-69 years, male
21.9
GTEX-1IL2V-1826-SM-ARU7R
70-79 years, male
21.9
GTEX-1LG7Y-2726-SM-D5OVW
50-59 years, male
21.7
GTEX-1F48J-2226-SM-7MXTN
50-59 years, female
21.4
GTEX-1A3MW-2226-SM-73KUX
60-69 years, female
21.3
GTEX-1HB9E-1826-SM-D4P33
50-59 years, male
21.1
GTEX-1C6VQ-2326-SM-7IGN1
50-59 years, male
20.7
GTEX-REY6-1826-SM-EAZAT
60-69 years, male
20.5
GTEX-1GF9W-1326-SM-7P8PX
60-69 years, male
20.3
GTEX-1497J-0826-SM-5NQAJ
60-69 years, male
20.0
GTEX-1MUQO-2526-SM-E9TJN
60-69 years, male
20.0
GTEX-147F4-2626-SM-5Q5CS
50-59 years, male
19.8
GTEX-1H3NZ-2126-SM-9WPQ6
60-69 years, male
19.4
GTEX-ZVZP-0926-SM-5GIDB
50-59 years, male
18.9
GTEX-11GS4-2326-SM-5A5KS
60-69 years, male
18.5
GTEX-11TTK-1926-SM-5PNW8
60-69 years, female
18.3
GTEX-1I1GP-1926-SM-CNNQU
50-59 years, male
18.2
GTEX-1JJ6O-2526-SM-AHZ3J
60-69 years, male
17.8
GTEX-1JMQK-1926-SM-CJI3B
60-69 years, male
17.8
GTEX-1JMPZ-1226-SM-ARU8Y
30-39 years, male
17.7
GTEX-1K9T9-1826-SM-CXZK2
50-59 years, female
17.7
GTEX-Y5V6-2026-SM-5IFHO
60-69 years, male
17.2
GTEX-P4QS-1126-SM-3NMD5
60-69 years, male
16.8
GTEX-12696-0926-SM-5FQTV
60-69 years, male
16.6
GTEX-13O1R-2526-SM-5N9FW
60-69 years, male
16.5
GTEX-1EKGG-2226-SM-7IGOA
60-69 years, male
16.5
GTEX-14C5O-2026-SM-5YYB1
60-69 years, male
15.9
GTEX-1AX8Z-2326-SM-731CR
60-69 years, male
15.9
GTEX-QDVN-1626-SM-48TZC
50-59 years, male
15.8
GTEX-13OVI-1126-SM-5KLZF
60-69 years, female
15.7
GTEX-1R9PO-1626-SM-E6CPT
60-69 years, female
15.7
GTEX-XPVG-0526-SM-4B65N
50-59 years, male
15.5
GTEX-1A8FM-2026-SM-7P8RN
50-59 years, female
15.2
GTEX-ZYFG-1626-SM-5GZYY
60-69 years, female
14.6
GTEX-1N2EF-1426-SM-EXUSH
60-69 years, male
14.6
GTEX-1PWST-2226-SM-EVR3G
70-79 years, male
14.5
GTEX-145MN-0326-SM-5QGQI
30-39 years, male
14.2
GTEX-QLQW-1626-SM-CMKFE
30-39 years, male
12.0
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Kidney - Medulla Average nTPM: 27.5
Samples: 4
Max nTPM: 36.8
Min nTPM: 20.2
Std nTPM: 5.9
Median nTPM: 26.5
GTEX-R55E-2026-SM-EZ6L1
20-29 years, male
36.8
GTEX-RU72-1926-SM-EAZ3F
50-59 years, female
26.6
GTEX-T5JC-1626-SM-EZ6KW
20-29 years, male
26.4
GTEX-TKQ2-0626-SM-EZ6LB
50-59 years, male
20.2
KIDNEY - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.