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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 9.2
Min nTPM: 1.1
Std nTPM: 2.2
Median nTPM: 2.4
GTEX-TSE9-2826-SM-4DXTF
60-69 years, female
9.2
GTEX-P78B-2326-SM-EZ6KO
40-49 years, female
3.5
GTEX-S32W-1526-SM-4AD6Z
50-59 years, female
3.2
GTEX-Q2AG-2326-SM-EZ6KY
40-49 years, female
3.0
GTEX-T5JW-0726-SM-4DM6D
20-29 years, female
2.4
GTEX-N7MT-0826-SM-EV794
60-69 years, female
2.2
GTEX-U3ZN-1626-SM-4DXTZ
30-39 years, female
1.6
GTEX-S341-1126-SM-4AD6T
40-49 years, female
1.5
GTEX-S4UY-1426-SM-4AD6Y
40-49 years, female
1.1
Cervix - Endocervix Average nTPM: 2.3
Samples: 10
Max nTPM: 6.2
Min nTPM: 1.1
Std nTPM: 1.3
Median nTPM: 2.0
GTEX-TSE9-2726-SM-4DXSQ
60-69 years, female
6.2
GTEX-S32W-1626-SM-4AD6G
50-59 years, female
2.9
GTEX-T5JW-0826-SM-EYYVD
20-29 years, female
2.5
GTEX-S341-1326-SM-4AD72
40-49 years, female
2.1
GTEX-T6MO-1426-SM-4DM73
40-49 years, female
2.0
GTEX-PLZ4-2226-SM-EZ6KS
50-59 years, female
2.0
GTEX-OHPN-2226-SM-E9TI7
60-69 years, female
1.6
GTEX-TML8-0726-SM-4DXTT
40-49 years, female
1.5
GTEX-ZPIC-1326-SM-DO91Y
40-49 years, female
1.5
GTEX-P78B-2426-SM-EWRM2
40-49 years, female
1.1
CERVIX - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
