Lung cancer

The upper left dot plot(s) shows the consistency between the cancer type related cell lines and their corresponding TCGA disease cohort based on Spearman correlation and normalized enrichment score (NES). In the lower left is a list of the cell lines ranked according to their similarity to the cancer type. By clicking on a cell line in the dot plot or in the ranked list lollipop plots showing the activity of cancer-related pathways inferred using PROGENy and CytoSig cytokines for that particular cell line will be displayed. For more details about the analysis see Methods summary and information about all cell lines can be found here.

Lung Adenocarcinoma (LUAD)

Explore the disease cohort in TCGA

Ranking Cell line Corr NES
1 NCI-H3255 0.78 2.2
2 NCI-H1734 0.78 2.35
3 RERF-LC-Ad1 0.78 2.16
4 HCC4006 0.78 2.2
5 HCC1195 0.77 2.08
6 HCC2935 0.78 1.89
6 NCI-H1781 0.77 1.97
8 NCI-H2347 0.77 2.03
9 NCI-H2291 0.78 1.88
10 HCC78 0.77 1.88
11 NCI-H2110 0.77 2.09
12 NCI-H1869 0.77 1.92
13 NCI-H2087 0.77 2.03
14 NCI-H441 0.76 2.08
15 NCI-H1437 0.77 1.94
16 SW900 0.78 1.76
17 NCI-H2122 0.77 1.83
18 HCC827 GR5 0.76 1.91
19 RERF-LC-KJ 0.77 1.78
20 NCI-H2126 0.76 1.81
21 NCI-H3122 0.77 1.74
22 NCI-H2444 0.77 1.68
23 EKVX 0.75 1.88
24 RERF-LC-MS 0.76 1.78
25 NCI-H727 0.75 2.03
26 NCI-H2228 0.78 1.56
27 NCI-H2023 0.76 1.79
27 NCI-H647 0.77 1.71
29 LCLC-97TM1 0.77 1.58
30 NCI-H1651 0.75 1.8
31 NCI-H1573 0.76 1.77
32 NCI-H1838 0.76 1.75
33 Calu-3 0.77 1.58
33 RERF-LC-Ad2 0.76 1.67
35 PC-14 0.77 1.59
36 NCI-H1568 0.75 1.88
37 NCI-H1648 0.78 1.46
37 NCI-H1793 0.75 1.83
39 NCI-H2342 0.75 1.73
40 NCI-H1395 0.75 1.67
40 NCI-H1666 0.77 1.5
42 NCI-H2170 0.76 1.55
43 NCI-H1944 0.74 1.81
44 Lu-65 0.74 1.76
45 HCC515 0.75 1.55
45 MOR/CPR 0.75 1.64
47 A-549 0.75 1.64
48 NCI-H2073 0.77 1.32
49 SK-MES-1 0.75 1.5
50 DMS 53 0.73 1.88
51 HCC1833 0.73 1.78
52 ABC-1 0.74 1.65
52 NCI-H1623 0.74 1.7
52 NCI-H358 0.74 1.62
55 NCI-H854 0.74 1.58
56 HCC827 0.76 1.38
56 NCI-H2009 0.75 1.43
56 Sq-1 0.76 1.32
59 BEN 0.73 1.8
60 PC-9 0.75 1.41
61 IA-LM 0.73 1.72
61 LUDLU-1 0.76 1.35
63 HCC1171 0.77 1.24
64 HCC2279 0.76 1.31
65 NCI-H1755 0.75 1.45
66 NCI-H1819 0.73 1.67
66 NCI-H292 0.76 1.28
68 COR-L23 0.74 1.53
69 ChaGo-K-1 0.74 1.54
69 NCI-H596 0.77 1.12
71 HCC95 0.74 1.48
71 NCI-H1650 0.75 1.32
73 NCI-H1373 0.75 1.32
74 COR-L95 0.72 1.72
74 HCC1588 0.75 1.29
76 NCI-H1355 0.73 1.55
77 NCI-H1563 0.75 1.39
78 KNS-62 0.77 1.16
79 DV-90 0.74 1.48
80 NCI-H2405 0.76 1.19
81 HCC44 0.75 1.29
82 T3M-10 0.77 1.05
83 CAL-12T 0.75 1.31
84 HOP-92 0.75 1.23
84 NCI-H2029 0.7 1.77
84 NCI-H510A 0.7 1.77
87 DMS 153 0.71 1.71
87 NCI-H1435 0.74 1.31
87 NCI-H460 0.72 1.59
90 COLO 668 0.71 1.67
91 SHP-77 0.69 1.81
92 LXF 289 0.75 1.27
93 NCI-H157 0.72 1.57
94 NCI-H2196 0.71 1.63
95 HCC366 0.74 1.27
96 HCC15 0.75 1.19
96 HCC2108 0.73 1.46
98 HCC1438 0.74 1.33
99 NCI-H2066 0.71 1.54
100 NCI-H2030 0.73 1.4
101 NCI-H661 0.72 1.51
102 NCI-H2085 0.74 1.21
103 NCI-H2172 0.72 1.46
104 NCI-H1048 0.72 1.48
105 NCI-H1975 0.75 1.05
105 RERF-LC-Sq1 0.74 1.28
107 NCI-H1155 0.69 1.62
108 DMS 79 0.68 1.66
109 NCI-H209 0.68 1.64
110 HCC364 0.75 1.07
111 COR-L105 0.74 1.19
112 Calu-1 0.74 1.22
112 EPLC-272H 0.75 1.08
114 NCI-H1915 0.7 1.52
115 Calu-6 0.73 1.26
116 LCLC-103H 0.73 1.24
117 HCC2814 0.74 1.17
117 JL-1 0.75 1.09
119 DMS 454 0.71 1.47
119 NCI-H2887 0.74 1.21
121 HOP-62 0.75 0.98
121 RERF-LC-A1 0.73 1.26
123 NCI-H1385 0.67 1.62
124 NCI-H146 0.67 1.6
125 NCI-H650 0.71 1.43
126 NCI-H322 0.74 1.07
127 COR-L279 0.68 1.52
128 COR-L88 0.69 1.46
129 NCI-H1792 0.74 1.04
130 NCI-H889 0.67 1.54
131 NCI-H1436 0.67 1.52
131 NCI-H1836 0.68 1.5
133 NCI-H226 0.73 1.21
134 COR-L311 0.67 1.5
134 NCI-H2882 0.73 1.2
136 NCI-H520 0.71 1.32
136 NCI-H526 0.7 1.39
138 NCI-H1618 0.7 1.37
139 HARA [Human squamous 0.73 1.1
139 NCI-H23 0.72 1.21
141 LC-1F 0.73 1.1
142 EBC-1 0.74 0.8
142 NCI-H2452 0.74 0.95
144 HCC33 0.65 1.51
144 LK-2 0.72 1.15
146 SCLC-21H 0.69 1.35
146 MPP 89 0.74 0.96
146 NCI-H2286 0.73 1.1
149 ACC-MESO-1 0.71 1.22
150 NCI-H69 0.66 1.43
151 NCI-H1930 0.66 1.44
152 HCC461 0.74 0.78
152 NCI-H1184 0.66 1.43
154 NCI-H810 0.69 1.31
155 SW1573 0.74 0.75
156 NCI-H2052 0.73 0.83
157 NCI-H211 0.69 1.26
158 COR-L47 0.68 1.3
159 NCI-H1694 0.65 1.4
160 HCC1359 0.72 0.97
160 IST-Mes2 0.74 0.64
162 NCI-H1581 0.69 1.23
163 NCI-H2227 0.65 1.33
164 IST-Mes1 0.73 0.76
165 HCC2450 0.71 1.07
166 LOU-NH91 0.72 0.93
166 NCI-H838 0.7 1.11
168 A-427 0.71 1.02
169 COR-L24 0.65 1.31
170 NCI-H28 0.72 0.94
171 NCI-H1693 0.71 0.98
171 SK-LU-1 0.72 0.84
173 Lu-99 0.72 0.65
174 DMS 114 0.69 1.14
174 NCI-H1876 0.69 1.11
174 SW1271 0.72 0.92
177 NCI-H2081 0.67 1.2
178 NCI-H1963 0.66 1.24
179 HCC2429 0.71 0.95
179 MSTO-211H 0.72 0.58
181 NCI-H196 0.72 0.72
181 NCI-H82 0.66 1.22
183 SBC-5 0.7 1.03
184 NCI-H524 0.65 1.22
185 NCI-H1092 0.65 1.22
186 DMS 273 0.7 1
186 NCI-H446 0.66 1.19
188 NCI-H522 0.7 0.96
189 NCI-H1703 0.71 0.62
190 NCI-H1341 0.71 0.76
191 NCI-H841 0.7 0.92
192 NCI-H2171 0.67 1.09
193 NCI-H1299 0.71 0.56
193 NCI-H2077 0.69 0.95
195 NCI-H2106 0.66 1.06
196 NCI-H1105 0.66 1.07
CELL LINE DATA
Cell line NCI-H3255
Patient: Female, 52
Disease subtype: Non-Small Cell Lung Cancer (NSCLC), Adenocarcinoma
Primary/metastasis: Primary
Sample collection site: Lung
Cellosaurus: CVCL_6831
PROGENy
CytoSig

Lung Squamous Cell Carcinoma (LUSC)

Explore the disease cohort in TCGA

Ranking Cell line Corr NES
1 NCI-H1648 0.8 2.1
2 HCC2814 0.79 2.09
2 LUDLU-1 0.79 2.17
4 KNS-62 0.8 2.03
5 HCC95 0.79 2.08
6 NCI-H1666 0.79 1.83
7 LC-1F 0.77 1.99
8 NCI-H1734 0.78 1.76
9 EPLC-272H 0.78 1.68
10 NCI-H596 0.79 1.65
11 PC-14 0.78 1.71
12 RERF-LC-MS 0.77 1.95
13 NCI-H2228 0.77 1.68
14 NCI-H292 0.77 1.65
15 HARA [Human squamous 0.77 1.65
16 NCI-H2170 0.76 1.8
16 RERF-LC-Sq1 0.76 1.76
18 NCI-H2023 0.76 1.79
19 NCI-H1793 0.75 1.78
20 NCI-H647 0.77 1.47
21 NCI-H1781 0.76 1.53
22 PC-9 0.76 1.55
23 HCC366 0.76 1.61
24 NCI-H2122 0.77 1.49
24 NCI-H3255 0.78 1.39
26 CAL-12T 0.76 1.47
26 RERF-LC-Ad1 0.77 1.41
28 NCI-H322 0.75 1.59
29 NCI-H1650 0.77 1.39
30 NCI-H1437 0.76 1.52
31 LXF 289 0.76 1.5
31 NCI-H1755 0.75 1.64
33 NCI-H1573 0.75 1.56
34 NCI-H1623 0.75 1.66
35 NCI-H2444 0.78 1.28
35 SK-MES-1 0.76 1.46
37 NCI-H1869 0.76 1.41
38 ChaGo-K-1 0.75 1.52
38 NCI-H1568 0.76 1.45
40 Calu-3 0.77 1.35
41 NCI-H1792 0.76 1.46
42 LK-2 0.75 1.61
43 HCC1438 0.75 1.49
43 MOR/CPR 0.75 1.52
45 JL-1 0.76 1.37
46 HCC2429 0.74 1.77
47 NCI-H2085 0.76 1.33
47 NCI-H2286 0.74 1.64
47 RERF-LC-Ad2 0.78 1.21
50 NCI-H157 0.74 1.74
51 NCI-H2110 0.76 1.31
52 NCI-H2405 0.77 1.25
53 EKVX 0.76 1.37
54 HCC2935 0.77 1.19
55 LCLC-103H 0.75 1.49
56 NCI-H1341 0.74 1.58
57 HCC15 0.75 1.44
57 NCI-H1435 0.74 1.51
59 SW900 0.78 1.11
60 NCI-H661 0.74 1.62
61 SBC-5 0.71 1.83
62 NCI-H2126 0.75 1.33
63 ABC-1 0.75 1.37
64 NCI-H1944 0.73 1.58
64 RERF-LC-A1 0.74 1.44
66 NCI-H2347 0.77 1.14
67 BEN 0.71 1.77
68 COR-L23 0.75 1.35
68 NCI-H2342 0.75 1.34
68 T3M-10 0.78 0.98
71 NCI-H2087 0.76 1.17
72 HCC4006 0.77 0.97
72 NCI-H2291 0.77 0.99
74 NCI-H460 0.74 1.47
75 NCI-H441 0.75 1.29
76 NCI-H520 0.73 1.49
76 NCI-H650 0.72 1.55
78 HCC1171 0.77 0.96
78 NCI-H2073 0.77 0.98
80 DMS 454 0.7 1.68
81 DMS 53 0.71 1.58
81 LCLC-97TM1 0.77 0.98
81 MPP 89 0.75 1.22
81 NCI-H841 0.72 1.54
85 DMS 114 0.71 1.59
85 HCC78 0.77 0.99
87 A-549 0.75 1.23
88 DV-90 0.74 1.37
88 NCI-H3122 0.77 0.89
90 NCI-H2009 0.76 1.07
91 HOP-62 0.76 0.98
92 NCI-H146 0.68 1.68
93 NCI-H1355 0.74 1.33
93 NCI-H2066 0.72 1.46
95 NCI-H1373 0.75 1.14
96 HCC44 0.76 1.05
96 NCI-H2887 0.74 1.36
96 NCI-H510A 0.71 1.5
99 NCI-H226 0.74 1.25
100 A-427 0.73 1.38
101 NCI-H1618 0.71 1.46
101 NCI-H2882 0.74 1.32
103 NCI-H2227 0.67 1.72
104 NCI-H1930 0.68 1.64
105 NCI-H2172 0.73 1.36
106 HCC2279 0.76 0.9
106 IST-Mes1 0.75 1.2
108 RERF-LC-KJ 0.75 1.02
109 NCI-H1563 0.75 1.05
110 HCC1195 0.76 0.85
111 NCI-H1975 0.76 0.88
112 NCI-H2052 0.75 0.99
112 Sq-1 0.76 0.85
114 SCLC-21H 0.7 1.44
115 HCC827 0.76 0.58
116 HOP-92 0.75 0.93
116 SW1271 0.73 1.27
118 NCI-H69 0.68 1.52
119 HCC2108 0.74 1.15
120 NCI-H1299 0.72 1.32
120 NCI-H1703 0.73 1.28
120 NCI-H358 0.74 1.13
123 NCI-H23 0.74 1.13
124 NCI-H1819 0.74 1.14
125 NCI-H838 0.72 1.3
126 NCI-H196 0.74 1.21
126 NCI-H2081 0.69 1.43
126 NCI-H727 0.73 1.23
129 NCI-H2029 0.7 1.38
130 NCI-H1693 0.72 1.26
130 SHP-77 0.69 1.4
132 NCI-H810 0.69 1.41
133 COR-L47 0.7 1.38
133 NCI-H28 0.73 1.23
135 NCI-H1836 0.69 1.41
136 NCI-H1651 0.75 0.97
137 HCC2450 0.73 1.22
138 NCI-H1838 0.75 0.79
139 DMS 273 0.72 1.23
139 NCI-H889 0.68 1.39
141 IST-Mes2 0.75 0.96
142 COR-L24 0.67 1.43
142 NCI-H2171 0.69 1.36
142 NCI-H2196 0.71 1.28
145 COR-L105 0.75 0.87
146 HCC364 0.75 0.55
146 NCI-H854 0.73 1.17
148 HCC1833 0.72 1.22
149 COR-L88 0.7 1.3
149 HCC1588 0.74 1.03
149 HCC33 0.67 1.43
152 COR-L279 0.69 1.34
153 IA-LM 0.74 1.07
153 NCI-H82 0.68 1.37
155 EBC-1 0.75 0.72
155 NCI-H1876 0.72 1.21
157 NCI-H2452 0.75 0.57
158 HCC827 GR5 0.75 0.77
158 NCI-H1155 0.71 1.25
160 COR-L95 0.72 1.14
160 SW1573 0.75 0.8
162 HCC461 0.75 0.79
163 DMS 153 0.72 1.16
164 Calu-1 0.75 0.71
164 NCI-H1048 0.74 0.96
164 NCI-H1436 0.69 1.26
167 NCI-H1915 0.71 1.2
168 NCI-H1694 0.68 1.33
169 HCC1359 0.74 0.62
170 Calu-6 0.74 0.64
170 HCC515 0.74 0.55
170 NCI-H211 0.71 1.14
173 COLO 668 0.7 1.19
174 NCI-H2030 0.74 0.84
175 MSTO-211H 0.74 0.64
176 Lu-99 0.74 0.56
177 NCI-H1385 0.67 1.25
177 NCI-H526 0.71 1.09
179 Lu-65 0.74 0.61
180 NCI-H446 0.68 1.2
180 NCI-H522 0.71 1.03
182 DMS 79 0.7 1.12
183 NCI-H1581 0.7 1.08
184 NCI-H1395 0.73 0.79
184 NCI-H209 0.7 1.12
186 LOU-NH91 0.73 0.6
186 SK-LU-1 0.74 0.54
188 ACC-MESO-1 0.72 0.81
189 NCI-H524 0.68 1.17
190 COR-L311 0.69 1.11
191 NCI-H2106 0.68 1.11
192 NCI-H1184 0.68 1.12
193 NCI-H2077 0.7 0.88
194 NCI-H1105 0.68 1.03
195 NCI-H1963 0.68 0.83
196 NCI-H1092 0.66 0.83
CELL LINE DATA
Cell line NCI-H1648
Patient: Male, 39
Disease subtype: Non-Small Cell Lung Cancer (NSCLC), Adenocarcinoma
Primary/metastasis: Metastasis
Sample collection site: Lymph node
Cellosaurus: CVCL_1482
PROGENy
CytoSig

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The Human Protein Atlas

The Human Protein Atlas project is funded
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