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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:37.1 nTPM
HPA:37.1 nTPM
GTEx:36.3 nTPM
FANTOM5:43.9 Scaled Tags Per Million
Pig:5.2 nTPM
Mouse:30.7 nTPM
Allen mouse:1.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 37.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 35.5
2411 Female, age 72, unknown 36.8
2586 Male, age 75, left hemisphere 36.8
2019 Male, age 18, unknown 36.7
1870 Female, age 42, unknown 36.0
2666 Male, age 74, left hemisphere 35.4
2828 Female, age 72, unknown 35.1
1833 Male, age 53, unknown 34.9
1827 Male, age 72, unknown 34.8
1830 Male, age 51, unknown 34.8
2219 Male, age 76, both hemispheres 33.2
Dorsal raphe nucleus
nTPM: 35.0
2750 Male, age 76, both hemispheres 35.9
2047 Male, age 72, unknown 35.5
2016 Female, age 72, unknown 35.1
1828 Male, age 53, unknown 34.7
2298 Female, age 72, unknown 34.0
Inferior colliculus
nTPM: 34.5
1890 Male, age 53, unknown 35.3
2097 Female, age 72, unknown 34.5
1848 Female, age 42, unknown 34.2
2849 Male, age 72, unknown 33.8
Median raphe nucleus
nTPM: 33.7
2220 Male, age 76, midline 33.7
Pedunculopontine tegmental nucleus
nTPM: 34.3
1921 Female, age 85, both hemispheres 35.6
2334 Male, age 80, both hemispheres 33.6
2338 Male, age 61, both hemispheres 33.6
Periaquaductal grey, anterior
nTPM: 35.0
2502 Female, age 75, unknown 35.2
1795 Male, age 51, unknown 35.0
1947 Male, age 18, unknown 34.7
Periaquaductal grey, dorsal
nTPM: 33.8
2464 Female, age 72, unknown 34.7
1831 Male, age 72, unknown 34.4
1840 Male, age 53, unknown 33.8
2850 Male, age 76, both hemispheres 32.3
Periaquaductal grey, lateral
nTPM: 34.1
2272 Male, age 74, both hemispheres 34.2
2140 Male, age 76, both hemispheres 34.1
2053 Male, age 18, unknown 33.9
Pretectal area
nTPM: 34.2
2407 Male, age 75, both hemispheres 35.5
1815 Male, age 53, unknown 34.9
1816 Male, age 51, unknown 34.8
1817 Female, age 42, unknown 34.6
2007 Male, age 72, unknown 34.6
2316 Male, age 76, right hemisphere 34.4
1944 Female, age 72, unknown 33.9
2224 Female, age 72, unknown 33.9
2825 Male, age 18, unknown 33.9
2667 Female, age 75, unknown 32.8
2273 Male, age 74, both hemispheres 32.7
Red nucleus
nTPM: 37.1
2588 Male, age 74, left hemisphere 40.4
2503 Female, age 72, unknown 39.3
1821 Female, age 72, unknown 37.4
2227 Male, age 72, unknown 37.4
1904 Male, age 53, unknown 37.3
2769 Male, age 72, unknown 37.3
2725 Female, age 75, unknown 36.9
1865 Male, age 51, unknown 36.2
1954 Female, age 42, unknown 36.2
2823 Male, age 76, right hemisphere 36.0
2584 Male, age 75, left hemisphere 35.8
2785 Male, age 18, unknown 35.4
Substantia nigra
nTPM: 35.0
2590 Female, age 75, unknown 36.8
2409 Female, age 72, unknown 36.5
2665 Male, age 74, both hemispheres 36.1
1851 Male, age 51, unknown 34.9
1941 Male, age 53, unknown 34.7
2699 Male, age 18, unknown 34.4
1889 Female, age 72, unknown 34.3
1916 Female, age 42, unknown 34.2
2241 Male, age 72, unknown 34.2
2583 Male, age 75, right hemisphere 33.8
Superior colliculus
nTPM: 34.4
2261 Male, age 18, unknown 36.0
2587 Male, age 74, left hemisphere 35.4
1895 Male, age 76, right hemisphere 34.6
1796 Male, age 53, unknown 34.4
2087 Female, age 72, unknown 34.3
2668 Female, age 75, unknown 34.3
1913 Female, age 42, unknown 34.2
1995 Male, age 72, unknown 34.2
1839 Male, age 51, unknown 33.7
2664 Male, age 75, both hemispheres 33.1
Ventral tegmental area
nTPM: 35.0
1942 Male, age 51, unknown 36.2
1915 Female, age 42, unknown 35.7
2223 Female, age 72, unknown 35.7
2410 Female, age 72, unknown 35.6
2021 Male, age 53, unknown 33.8
2218 Male, age 76, both hemispheres 32.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 36.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 36.3
Samples: 139

Max nTPM: 103.5
Min nTPM: 19.4
Std nTPM: 12.3
Median nTPM: 33.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 103.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 80.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 73.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 65.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 65.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 60.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 60.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 56.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 56.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 55.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 55.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 54.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 53.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 52.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 51.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 51.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 50.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 48.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 48.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 48.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 47.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 46.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 45.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 45.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 44.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 44.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 44.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 43.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 43.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 42.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 42.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 42.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 42.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 42.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 42.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 41.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 41.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 41.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 40.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 40.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 40.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 39.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 39.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 39.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 39.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 39.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 38.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 38.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 38.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 38.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 37.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 37.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 36.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 36.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 36.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 35.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 35.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 35.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 34.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 34.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 34.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 34.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 34.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 34.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 34.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 33.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 33.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 33.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 33.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 33.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 31.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 31.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 31.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 31.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 31.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 31.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 31.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 31.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 31.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 31.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 31.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 31.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 30.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 30.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 30.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 30.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 30.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 29.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 29.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 29.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 29.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 29.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 29.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 29.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 29.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 28.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 28.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 28.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 28.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 28.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 28.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 28.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 28.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 28.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 28.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 28.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 27.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 27.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 27.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 27.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 27.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 26.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 26.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 26.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 26.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 26.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 26.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 26.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 26.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 26.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 25.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 25.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 25.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 25.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 25.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 24.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 24.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 24.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 24.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 23.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 23.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 23.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 23.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 22.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 22.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 21.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 21.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 21.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 19.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 43.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 43.9
FF:10158-103A5 76 years, female 43.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 5.2
Pig sample Sample description nTPM
Midbrain
nTPM: 5.2
Samples: 4

Max nTPM: 6.6
Min nTPM: 4.5
Sample A Female 6.6
Sample B Female 4.5
Sample C Male 4.8
Sample D Male 5.0
Periaqueductal gray
nTPM: 4.5
Samples: 3

Max nTPM: 4.8
Min nTPM: 4.3
Sample B Female 4.8
Sample C Male 4.5
Sample D Male 4.3
Substantia nigra
nTPM: 5.0
Samples: 4

Max nTPM: 5.2
Min nTPM: 4.7
Sample A Female 4.8
Sample B Female 4.7
Sample C Male 5.2
Sample D Male 5.2
Superior colliculi
nTPM: 5.0
Samples: 4

Max nTPM: 5.3
Min nTPM: 4.5
Sample A Female 5.3
Sample B Female 4.5
Sample C Male 5.0
Sample D Male 5.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 30.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 30.7
Samples: 4

Max nTPM: 32.0
Min nTPM: 29.9
Sample A Male 29.9
Sample B Male 30.9
Sample C Female 32.0
Sample D Female 29.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.2
74822880 Antisense, RP_051130_02_E10, Mouse strain C57BL/6J (56 days, male) 1.2

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