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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:48.5 nTPM
HPA:48.5 nTPM
GTEx:87.6 nTPM
FANTOM5:118.3 Scaled Tags Per Million
Pig:104.6 nTPM
Mouse:6.0 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 48.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 38.8
2828 Female, age 72, unknown 52.4
2666 Male, age 74, left hemisphere 44.5
1833 Male, age 53, unknown 40.3
1830 Male, age 51, unknown 39.6
2219 Male, age 76, both hemispheres 38.9
2019 Male, age 18, unknown 37.4
2586 Male, age 75, left hemisphere 36.7
1827 Male, age 72, unknown 33.3
1870 Female, age 42, unknown 32.9
2411 Female, age 72, unknown 32.1
Dorsal raphe nucleus
nTPM: 46.8
2047 Male, age 72, unknown 61.4
1828 Male, age 53, unknown 59.5
2016 Female, age 72, unknown 39.2
2298 Female, age 72, unknown 38.3
2750 Male, age 76, both hemispheres 35.8
Inferior colliculus
nTPM: 40.6
2849 Male, age 72, unknown 56.3
1848 Female, age 42, unknown 40.9
1890 Male, age 53, unknown 34.2
2097 Female, age 72, unknown 30.9
Median raphe nucleus
nTPM: 48.5
2220 Male, age 76, midline 48.5
Pedunculopontine tegmental nucleus
nTPM: 35.9
2334 Male, age 80, both hemispheres 39.6
2338 Male, age 61, both hemispheres 37.6
1921 Female, age 85, both hemispheres 30.5
Periaquaductal grey, anterior
nTPM: 33.7
1795 Male, age 51, unknown 35.7
2502 Female, age 75, unknown 35.7
1947 Male, age 18, unknown 29.5
Periaquaductal grey, dorsal
nTPM: 43.4
2850 Male, age 76, both hemispheres 53.3
2464 Female, age 72, unknown 46.3
1840 Male, age 53, unknown 39.8
1831 Male, age 72, unknown 34.3
Periaquaductal grey, lateral
nTPM: 40.9
2140 Male, age 76, both hemispheres 46.7
2272 Male, age 74, both hemispheres 43.6
2053 Male, age 18, unknown 32.4
Pretectal area
nTPM: 35.3
2825 Male, age 18, unknown 41.8
2273 Male, age 74, both hemispheres 39.5
1817 Female, age 42, unknown 36.6
2224 Female, age 72, unknown 35.1
2407 Male, age 75, both hemispheres 35.1
2667 Female, age 75, unknown 34.4
2007 Male, age 72, unknown 34.2
1815 Male, age 53, unknown 33.6
1944 Female, age 72, unknown 33.6
2316 Male, age 76, right hemisphere 33.2
1816 Male, age 51, unknown 31.4
Red nucleus
nTPM: 42.0
2503 Female, age 72, unknown 47.5
2823 Male, age 76, right hemisphere 46.4
2769 Male, age 72, unknown 45.7
2227 Male, age 72, unknown 45.3
2725 Female, age 75, unknown 44.3
2584 Male, age 75, left hemisphere 42.5
1954 Female, age 42, unknown 41.2
1865 Male, age 51, unknown 41.0
2785 Male, age 18, unknown 39.6
2588 Male, age 74, left hemisphere 37.7
1821 Female, age 72, unknown 36.8
1904 Male, age 53, unknown 36.3
Substantia nigra
nTPM: 39.9
2699 Male, age 18, unknown 62.5
2665 Male, age 74, both hemispheres 43.1
1916 Female, age 42, unknown 42.9
1851 Male, age 51, unknown 40.1
1941 Male, age 53, unknown 39.5
2590 Female, age 75, unknown 39.1
2583 Male, age 75, right hemisphere 36.4
2409 Female, age 72, unknown 34.2
1889 Female, age 72, unknown 33.8
2241 Male, age 72, unknown 27.3
Superior colliculus
nTPM: 35.2
2587 Male, age 74, left hemisphere 38.9
1796 Male, age 53, unknown 38.2
1839 Male, age 51, unknown 37.5
2087 Female, age 72, unknown 37.1
2664 Male, age 75, both hemispheres 36.5
1995 Male, age 72, unknown 36.4
1895 Male, age 76, right hemisphere 33.9
2668 Female, age 75, unknown 31.3
1913 Female, age 42, unknown 31.1
2261 Male, age 18, unknown 30.6
Ventral tegmental area
nTPM: 38.7
2223 Female, age 72, unknown 45.0
1915 Female, age 42, unknown 38.8
2218 Male, age 76, both hemispheres 38.7
2021 Male, age 53, unknown 37.3
2410 Female, age 72, unknown 36.9
1942 Male, age 51, unknown 35.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 87.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 87.6
Samples: 139

Max nTPM: 288.2
Min nTPM: 12.8
Std nTPM: 44.2
Median nTPM: 82.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 288.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 257.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 221.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 194.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 173.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 167.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 161.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 160.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 157.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 152.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 150.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 150.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 148.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 147.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 147.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 140.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 137.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 135.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 132.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 132.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 128.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 128.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 125.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 124.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 122.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 117.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 116.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 112.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 112.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 111.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 110.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 109.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 108.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 108.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 108.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 108.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 107.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 107.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 107.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 107.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 106.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 106.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 105.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 100.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 99.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 99.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 99.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 99.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 98.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 97.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 96.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 91.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 90.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 88.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 88.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 87.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 87.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 87.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 87.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 85.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 85.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 85.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 85.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 84.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 83.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 83.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 82.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 82.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 82.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 82.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 82.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 80.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 78.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 78.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 77.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 77.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 76.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 75.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 74.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 73.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 72.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 71.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 70.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 68.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 68.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 67.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 67.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 67.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 67.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 64.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 64.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 64.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 62.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 62.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 61.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 61.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 60.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 60.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 59.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 58.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 58.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 58.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 58.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 57.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 56.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 56.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 56.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 55.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 54.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 53.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 52.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 52.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 51.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 50.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 50.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 50.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 49.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 49.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 49.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 48.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 48.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 47.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 46.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 45.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 42.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 39.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 38.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 38.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 37.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 34.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 30.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 28.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 26.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 22.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 21.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 18.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 17.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 12.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 118.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 118.3
FF:10158-103A5 76 years, female 118.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 104.6
Pig sample Sample description nTPM
Midbrain
nTPM: 103.3
Samples: 4

Max nTPM: 177.3
Min nTPM: 55.7
Sample A Female 177.3
Sample B Female 85.7
Sample C Male 94.4
Sample D Male 55.7
Periaqueductal gray
nTPM: 78.1
Samples: 3

Max nTPM: 81.6
Min nTPM: 75.2
Sample B Female 77.6
Sample C Male 81.6
Sample D Male 75.2
Substantia nigra
nTPM: 93.1
Samples: 4

Max nTPM: 115.7
Min nTPM: 79.3
Sample A Female 115.7
Sample B Female 91.6
Sample C Male 85.6
Sample D Male 79.3
Superior colliculi
nTPM: 104.6
Samples: 4

Max nTPM: 128.9
Min nTPM: 75.0
Sample A Female 128.9
Sample B Female 75.0
Sample C Male 107.4
Sample D Male 107.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 6.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 6.0
Samples: 4

Max nTPM: 8.6
Min nTPM: 4.3
Sample A Male 8.6
Sample B Male 4.3
Sample C Female 5.4
Sample D Female 5.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
74882616 Antisense, RP_060315_04_F07, Mouse strain C57BL/6J (56 days, male) 0.1
69735162 Antisense, RP_050503_02_B12, Mouse strain C57BL/6J (56 days, male) 0.0

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