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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:141.0 nTPM
HPA:141.0 nTPM
GTEx:163.1 nTPM
FANTOM5:407.6 Scaled Tags Per Million
Pig:153.3 nTPM
Mouse:143.4 nTPM
Allen mouse:2.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 141.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 124.2
2411 Female, age 72, unknown 141.6
1830 Male, age 51, unknown 140.7
1833 Male, age 53, unknown 139.6
1870 Female, age 42, unknown 136.2
2019 Male, age 18, unknown 131.0
2828 Female, age 72, unknown 129.0
1827 Male, age 72, unknown 115.4
2219 Male, age 76, both hemispheres 106.6
2666 Male, age 74, left hemisphere 105.3
2586 Male, age 75, left hemisphere 96.7
Dorsal raphe nucleus
nTPM: 121.5
2750 Male, age 76, both hemispheres 139.8
2016 Female, age 72, unknown 126.4
2298 Female, age 72, unknown 119.7
1828 Male, age 53, unknown 116.8
2047 Male, age 72, unknown 104.7
Inferior colliculus
nTPM: 108.5
2097 Female, age 72, unknown 112.2
1848 Female, age 42, unknown 109.3
1890 Male, age 53, unknown 106.6
2849 Male, age 72, unknown 106.1
Median raphe nucleus
nTPM: 112.9
2220 Male, age 76, midline 112.9
Pedunculopontine tegmental nucleus
nTPM: 126.6
2338 Male, age 61, both hemispheres 130.9
2334 Male, age 80, both hemispheres 130.6
1921 Female, age 85, both hemispheres 118.2
Periaquaductal grey, anterior
nTPM: 110.8
1947 Male, age 18, unknown 115.4
2502 Female, age 75, unknown 109.1
1795 Male, age 51, unknown 107.8
Periaquaductal grey, dorsal
nTPM: 113.6
2850 Male, age 76, both hemispheres 122.8
2464 Female, age 72, unknown 121.3
1831 Male, age 72, unknown 112.2
1840 Male, age 53, unknown 98.2
Periaquaductal grey, lateral
nTPM: 118.8
2272 Male, age 74, both hemispheres 124.5
2140 Male, age 76, both hemispheres 119.7
2053 Male, age 18, unknown 112.1
Pretectal area
nTPM: 115.4
2316 Male, age 76, right hemisphere 135.5
2273 Male, age 74, both hemispheres 134.0
1815 Male, age 53, unknown 128.3
1817 Female, age 42, unknown 121.1
2224 Female, age 72, unknown 114.9
2667 Female, age 75, unknown 113.9
2825 Male, age 18, unknown 112.7
2007 Male, age 72, unknown 108.9
2407 Male, age 75, both hemispheres 105.0
1816 Male, age 51, unknown 97.9
1944 Female, age 72, unknown 97.3
Red nucleus
nTPM: 141.0
1904 Male, age 53, unknown 168.5
1821 Female, age 72, unknown 164.7
1865 Male, age 51, unknown 153.4
2503 Female, age 72, unknown 147.7
1954 Female, age 42, unknown 147.3
2227 Male, age 72, unknown 146.3
2823 Male, age 76, right hemisphere 144.2
2769 Male, age 72, unknown 142.1
2785 Male, age 18, unknown 141.7
2725 Female, age 75, unknown 126.8
2588 Male, age 74, left hemisphere 106.9
2584 Male, age 75, left hemisphere 102.3
Substantia nigra
nTPM: 110.9
2590 Female, age 75, unknown 125.5
1889 Female, age 72, unknown 114.7
1851 Male, age 51, unknown 114.5
2409 Female, age 72, unknown 113.1
2699 Male, age 18, unknown 112.3
2583 Male, age 75, right hemisphere 109.1
1941 Male, age 53, unknown 107.6
2241 Male, age 72, unknown 107.1
1916 Female, age 42, unknown 104.1
2665 Male, age 74, both hemispheres 101.1
Superior colliculus
nTPM: 123.3
1995 Male, age 72, unknown 159.1
1913 Female, age 42, unknown 157.0
2587 Male, age 74, left hemisphere 127.6
1895 Male, age 76, right hemisphere 127.2
1839 Male, age 51, unknown 121.2
1796 Male, age 53, unknown 115.8
2668 Female, age 75, unknown 113.4
2261 Male, age 18, unknown 109.1
2087 Female, age 72, unknown 105.5
2664 Male, age 75, both hemispheres 96.7
Ventral tegmental area
nTPM: 126.6
2223 Female, age 72, unknown 161.0
2410 Female, age 72, unknown 138.0
1942 Male, age 51, unknown 118.2
1915 Female, age 42, unknown 115.7
2218 Male, age 76, both hemispheres 115.0
2021 Male, age 53, unknown 111.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 163.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 163.1
Samples: 139

Max nTPM: 488.6
Min nTPM: 55.1
Std nTPM: 63.9
Median nTPM: 145.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 488.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 361.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 327.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 323.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 313.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 291.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 291.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 272.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 269.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 266.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 255.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 251.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 250.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 248.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 243.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 243.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 241.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 237.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 235.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 229.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 227.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 226.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 224.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 219.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 218.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 214.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 214.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 210.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 207.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 205.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 204.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 204.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 202.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 196.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 195.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 195.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 193.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 185.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 183.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 182.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 181.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 179.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 178.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 177.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 176.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 175.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 174.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 173.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 171.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 171.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 171.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 165.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 163.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 161.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 161.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 161.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 160.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 154.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 151.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 151.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 151.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 150.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 150.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 149.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 148.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 146.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 146.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 146.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 145.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 145.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 144.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 144.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 141.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 141.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 140.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 140.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 140.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 139.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 139.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 137.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 136.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 135.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 134.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 133.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 132.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 131.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 130.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 130.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 129.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 129.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 129.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 128.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 128.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 127.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 127.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 127.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 126.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 125.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 122.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 122.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 122.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 122.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 121.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 121.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 120.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 119.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 119.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 119.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 118.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 118.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 118.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 118.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 111.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 111.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 108.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 108.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 107.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 107.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 106.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 106.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 106.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 105.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 103.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 103.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 103.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 100.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 99.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 98.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 98.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 97.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 97.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 94.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 90.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 86.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 86.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 81.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 80.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 80.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 55.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 407.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 407.6
FF:10158-103A5 76 years, female 407.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 153.3
Pig sample Sample description nTPM
Midbrain
nTPM: 148.7
Samples: 4

Max nTPM: 308.3
Min nTPM: 65.8
Sample A Female 308.3
Sample B Female 132.1
Sample C Male 88.6
Sample D Male 65.8
Periaqueductal gray
nTPM: 122.3
Samples: 3

Max nTPM: 133.5
Min nTPM: 108.1
Sample B Female 125.4
Sample C Male 108.1
Sample D Male 133.5
Substantia nigra
nTPM: 153.4
Samples: 4

Max nTPM: 209.1
Min nTPM: 116.8
Sample A Female 169.8
Sample B Female 117.7
Sample C Male 116.8
Sample D Male 209.1
Superior colliculi
nTPM: 115.3
Samples: 4

Max nTPM: 127.8
Min nTPM: 91.0
Sample A Female 127.8
Sample B Female 91.0
Sample C Male 126.4
Sample D Male 116.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 143.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 143.4
Samples: 4

Max nTPM: 147.2
Min nTPM: 138.5
Sample A Male 147.2
Sample B Male 138.5
Sample C Female 143.5
Sample D Female 144.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.1
69540635 Antisense, RP_050426_02_B06, Mouse strain C57BL/6J (56 days, male) 3.3
73520971 Antisense, RP_051017_04_E11, Mouse strain C57BL/6J (56 days, male) 1.0

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