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  • STMN4
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:152.3 nTPM
HPA:152.3 nTPM
GTEx:200.4 nTPM
FANTOM5:28.8 Scaled Tags Per Million
Pig:248.0 nTPM
Mouse:259.2 nTPM
Allen mouse:4.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 152.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 129.5
2411 Female, age 72, unknown 147.7
1870 Female, age 42, unknown 142.5
1830 Male, age 51, unknown 140.9
2019 Male, age 18, unknown 138.3
1833 Male, age 53, unknown 131.3
2666 Male, age 74, left hemisphere 129.3
2828 Female, age 72, unknown 127.7
1827 Male, age 72, unknown 125.2
2219 Male, age 76, both hemispheres 111.3
2586 Male, age 75, left hemisphere 100.3
Dorsal raphe nucleus
nTPM: 115.6
2750 Male, age 76, both hemispheres 175.0
1828 Male, age 53, unknown 107.2
2298 Female, age 72, unknown 99.4
2047 Male, age 72, unknown 98.2
2016 Female, age 72, unknown 98.0
Inferior colliculus
nTPM: 111.3
1848 Female, age 42, unknown 116.8
2849 Male, age 72, unknown 113.8
2097 Female, age 72, unknown 108.2
1890 Male, age 53, unknown 106.5
Median raphe nucleus
nTPM: 126.0
2220 Male, age 76, midline 126.0
Pedunculopontine tegmental nucleus
nTPM: 133.4
2334 Male, age 80, both hemispheres 135.2
2338 Male, age 61, both hemispheres 133.2
1921 Female, age 85, both hemispheres 131.7
Periaquaductal grey, anterior
nTPM: 108.4
1947 Male, age 18, unknown 113.2
2502 Female, age 75, unknown 107.1
1795 Male, age 51, unknown 104.9
Periaquaductal grey, dorsal
nTPM: 98.5
2464 Female, age 72, unknown 110.4
1831 Male, age 72, unknown 107.5
1840 Male, age 53, unknown 91.8
2850 Male, age 76, both hemispheres 84.5
Periaquaductal grey, lateral
nTPM: 103.4
2272 Male, age 74, both hemispheres 116.8
2053 Male, age 18, unknown 108.5
2140 Male, age 76, both hemispheres 84.7
Pretectal area
nTPM: 122.1
1817 Female, age 42, unknown 145.9
1815 Male, age 53, unknown 145.4
2007 Male, age 72, unknown 139.7
1944 Female, age 72, unknown 139.6
2316 Male, age 76, right hemisphere 125.4
1816 Male, age 51, unknown 117.4
2825 Male, age 18, unknown 113.3
2273 Male, age 74, both hemispheres 111.1
2407 Male, age 75, both hemispheres 109.9
2224 Female, age 72, unknown 105.8
2667 Female, age 75, unknown 89.0
Red nucleus
nTPM: 152.3
2823 Male, age 76, right hemisphere 174.4
1865 Male, age 51, unknown 173.7
2588 Male, age 74, left hemisphere 162.2
1904 Male, age 53, unknown 157.7
2725 Female, age 75, unknown 154.7
2785 Male, age 18, unknown 154.4
2503 Female, age 72, unknown 150.6
1954 Female, age 42, unknown 148.2
1821 Female, age 72, unknown 145.3
2227 Male, age 72, unknown 142.4
2769 Male, age 72, unknown 141.7
2584 Male, age 75, left hemisphere 122.9
Substantia nigra
nTPM: 107.0
1889 Female, age 72, unknown 135.4
2590 Female, age 75, unknown 126.6
2583 Male, age 75, right hemisphere 111.2
1851 Male, age 51, unknown 108.5
2409 Female, age 72, unknown 106.3
1941 Male, age 53, unknown 99.6
1916 Female, age 42, unknown 98.3
2241 Male, age 72, unknown 97.6
2665 Male, age 74, both hemispheres 94.9
2699 Male, age 18, unknown 91.2
Superior colliculus
nTPM: 132.9
2668 Female, age 75, unknown 156.2
1913 Female, age 42, unknown 147.1
2587 Male, age 74, left hemisphere 141.3
1995 Male, age 72, unknown 138.7
2087 Female, age 72, unknown 135.3
1895 Male, age 76, right hemisphere 134.9
1796 Male, age 53, unknown 134.0
2261 Male, age 18, unknown 132.9
1839 Male, age 51, unknown 115.0
2664 Male, age 75, both hemispheres 93.4
Ventral tegmental area
nTPM: 118.5
2223 Female, age 72, unknown 140.7
2218 Male, age 76, both hemispheres 119.5
2410 Female, age 72, unknown 119.3
2021 Male, age 53, unknown 112.2
1942 Male, age 51, unknown 111.4
1915 Female, age 42, unknown 107.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 200.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 200.4
Samples: 139

Max nTPM: 932.7
Min nTPM: 30.7
Std nTPM: 151.6
Median nTPM: 158.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 932.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 833.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 738.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 667.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 648.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 559.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 466.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 465.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 436.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 423.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 421.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 419.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 399.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 377.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 371.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 364.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 357.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 347.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 334.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 326.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 315.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 313.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 312.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 310.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 306.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 287.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 287.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 278.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 275.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 246.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 244.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 244.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 244.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 242.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 231.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 228.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 225.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 221.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 220.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 219.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 217.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 215.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 214.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 213.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 213.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 210.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 209.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 206.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 206.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 205.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 199.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 197.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 194.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 192.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 191.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 187.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 184.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 183.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 181.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 180.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 176.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 174.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 173.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 173.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 168.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 168.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 163.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 162.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 162.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 158.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 156.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 153.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 152.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 152.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 151.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 149.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 148.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 148.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 147.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 145.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 143.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 143.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 140.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 138.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 137.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 134.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 130.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 130.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 130.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 128.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 127.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 127.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 121.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 119.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 118.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 116.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 113.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 113.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 112.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 111.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 109.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 108.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 105.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 104.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 104.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 103.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 100.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 100.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 97.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 97.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 96.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 95.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 92.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 89.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 88.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 87.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 86.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 85.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 85.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 85.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 84.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 83.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 80.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 78.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 65.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 61.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 57.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 56.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 53.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 51.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 50.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 50.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 48.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 47.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 40.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 40.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 38.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 33.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 30.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 28.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 28.8
FF:10158-103A5 76 years, female 28.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 248.0
Pig sample Sample description nTPM
Midbrain
nTPM: 248.0
Samples: 4

Max nTPM: 436.8
Min nTPM: 162.6
Sample A Female 436.8
Sample B Female 196.8
Sample C Male 195.8
Sample D Male 162.6
Periaqueductal gray
nTPM: 139.1
Samples: 3

Max nTPM: 151.0
Min nTPM: 125.7
Sample B Female 151.0
Sample C Male 125.7
Sample D Male 140.6
Substantia nigra
nTPM: 192.6
Samples: 4

Max nTPM: 297.0
Min nTPM: 104.3
Sample A Female 202.5
Sample B Female 104.3
Sample C Male 166.7
Sample D Male 297.0
Superior colliculi
nTPM: 194.4
Samples: 4

Max nTPM: 238.5
Min nTPM: 102.1
Sample A Female 217.0
Sample B Female 102.1
Sample C Male 220.1
Sample D Male 238.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 259.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 259.2
Samples: 4

Max nTPM: 275.1
Min nTPM: 248.3
Sample A Male 275.1
Sample B Male 248.3
Sample C Female 253.3
Sample D Female 260.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.6
1007 Antisense, RP_Baylor_103218, Mouse strain C57BL/6J (56 days, male) 8.3
1006 Antisense, RP_Baylor_103218, Mouse strain C57BL/6J (56 days, male) 7.7
1008 Sense, RPS_Baylor_37084, Mouse strain C57BL/6J (56 days, male) 0.8

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