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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:47.1 nTPM
HPA:47.1 nTPM
FANTOM5:188.6 Scaled Tags Per Million
Pig:103.1 nTPM
Mouse:74.9 nTPM
Allen mouse:6.9 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 47.1
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 34.3
2301 Female, age 85, both hemispheres 46.1
2188 Female, age 91, both hemispheres 41.6
2090 Male, age 80, both hemispheres 32.6
1984 Male, age 76, both hemispheres 17.0
Area postrema
nTPM: 16.4
2306 Male, age 80, both hemispheres 20.2
2054 Male, age 76, both hemispheres 17.5
2799 Male, age 61, both hemispheres 11.4
Cuneate nuclei
nTPM: 26.6
2381 Male, age 80, both hemispheres 34.4
2376 Male, age 61, both hemispheres 23.1
2131 Male, age 76, both hemispheres 22.2
Dorsal cochlear nucleus
nTPM: 22.5
2187 Female, age 91, both hemispheres 34.5
2802 Male, age 74, right hemisphere 22.1
2378 Male, age 80, both hemispheres 20.6
2058 Male, age 76, both hemispheres 19.8
2370 Male, age 61, both hemispheres 15.4
Dorsal medullary reticular nucleus
nTPM: 26.5
2088 Male, age 76, both hemispheres 31.2
2373 Male, age 61, both hemispheres 25.1
2040 Female, age 85, both hemispheres 23.2
Dorsal motor vagal complex
nTPM: 16.2
2185 Male, age 76, both hemispheres 22.5
2807 Female, age 85, both hemispheres 19.4
2000 Male, age 74, unknown 19.2
2844 Male, age 55, unknown 15.6
2797 Male, age 61, both hemispheres 13.8
2813 Female, age 72, unknown 13.3
2133 Female, age 91, both hemispheres 13.2
2643 Male, age 74, both hemispheres 12.2
Dorsal tegmental nucleus
nTPM: 20.7
2083 Male, age 80, both hemispheres 27.0
2326 Male, age 74, both hemispheres 26.4
1936 Male, age 76, left hemisphere 19.0
2358 Male, age 61, both hemispheres 10.6
Dorsolateral tegmental area
nTPM: 23.6
2751 Female, age 85, both hemispheres 41.1
2654 Male, age 80, both hemispheres 25.0
2360 Male, age 74, both hemispheres 18.9
2337 Male, age 61, both hemispheres 18.8
2141 Male, age 76, both hemispheres 14.3
Gigantocellular reticular nuclei, medullary
nTPM: 25.7
2314 Male, age 61, both hemispheres 36.3
2387 Female, age 91, both hemispheres 33.4
1876 Female, age 85, both hemispheres 31.1
2310 Male, age 80, both hemispheres 21.8
2022 Male, age 76, right hemisphere 17.9
2462 Male, age 74, both hemispheres 13.9
Gigantocellular reticular nuclei, pars
nTPM: 23.3
2336 Male, age 61, both hemispheres 25.9
2706 Male, age 80, both hemispheres 24.7
2330 Male, age 80, both hemispheres 24.1
2084 Female, age 85, both hemispheres 23.9
2168 Male, age 76, both hemispheres 18.1
Inferior olive
nTPM: 26.5
2085 Female, age 85, both hemispheres 31.8
2178 Male, age 61, both hemispheres 28.9
2379 Male, age 80, both hemispheres 25.3
2563 Male, age 74, both hemispheres 24.0
2628 Female, age 91, both hemispheres 22.7
Kolliker-Fuse nucleus
nTPM: 24.6
2793 Female, age 91, left hemisphere 37.7
2163 Male, age 80, both hemispheres 22.6
2315 Male, age 76, right hemisphere 13.6
Lateral lemniscal nuclei
nTPM: 23.8
2320 Female, age 91, left hemisphere 34.0
2453 Male, age 74, right hemisphere 24.9
2036 Male, age 80, both hemispheres 23.7
2746 Female, age 85, left hemisphere 19.4
2169 Male, age 76, both hemispheres 16.8
Lateral medullary reticular nucleus
nTPM: 31.2
2305 Male, age 74, both hemispheres 44.0
2852 Male, age 80, both hemispheres 33.6
2190 Female, age 85, both hemispheres 33.3
2374 Male, age 61, both hemispheres 31.6
2804 Female, age 91, both hemispheres 24.1
2044 Male, age 76, both hemispheres 20.5
Lateral parabrachial nucleus
nTPM: 24.1
2792 Male, age 76, both hemispheres 40.3
2013 Male, age 80, both hemispheres 21.6
2790 Male, age 61, both hemispheres 21.6
2139 Female, age 85, right hemisphere 12.8
Lateral vestibular nucleus
nTPM: 23.4
2311 Male, age 80, both hemispheres 25.9
2184 Male, age 76, both hemispheres 21.0
Locus coeruleus
nTPM: 14.2
2162 Male, age 80, both hemispheres 19.5
2014 Male, age 55, unknown 16.3
2720 Male, age 74, both hemispheres 15.4
2788 Male, age 74, unknown 14.8
2317 Female, age 72, unknown 12.1
2123 Female, age 91, both hemispheres 11.3
1980 Male, age 76, both hemispheres 10.1
Medial olivary nucleus
nTPM: 32.1
1962 Male, age 76, both hemispheres 49.4
1943 Male, age 61, both hemispheres 30.7
2138 Female, age 91, both hemispheres 25.2
2851 Male, age 80, both hemispheres 23.3
Medial parabrachial nucleus
nTPM: 28.6
2170 Female, age 91, both hemispheres 40.9
2463 Female, age 85, right hemisphere 33.5
2786 Male, age 76, both hemispheres 26.7
2854 Male, age 80, both hemispheres 26.5
2156 Male, age 61, both hemispheres 15.6
Medial periolivary nuclei
nTPM: 23.9
2458 Female, age 91, both hemispheres 33.6
2791 Male, age 74, right hemisphere 30.6
2081 Male, age 80, both hemispheres 28.6
2171 Female, age 85, both hemispheres 14.5
2063 Male, age 76, both hemispheres 12.3
Medial vestibular nucleus
nTPM: 22.7
2801 Male, age 74, both hemispheres 35.9
2803 Female, age 91, both hemispheres 28.8
2093 Male, age 80, both hemispheres 25.5
2743 Female, age 85, both hemispheres 20.9
2624 Male, age 61, both hemispheres 14.8
2134 Male, age 76, both hemispheres 10.4
Motor facial nucleus
nTPM: 22.9
2365 Male, age 74, right hemisphere 30.2
2697 Female, age 85, both hemispheres 29.6
2126 Male, age 61, both hemispheres 26.7
2795 Female, age 91, both hemispheres 21.0
2327 Male, age 80, both hemispheres 18.4
2062 Male, age 76, both hemispheres 11.7
Motor hypoglossal nucleus
nTPM: 23.5
2182 Male, age 80, both hemispheres 32.1
2125 Female, age 91, both hemispheres 29.2
2132 Female, age 85, both hemispheres 25.3
2277 Male, age 76, both hemispheres 16.1
2461 Male, age 61, both hemispheres 15.0
Motor trigeminal nucleus
nTPM: 25.4
2321 Female, age 91, both hemispheres 37.1
2560 Male, age 74, both hemispheres 31.4
2309 Male, age 76, both hemispheres 24.2
2079 Male, age 80, both hemispheres 19.6
2335 Male, age 61, both hemispheres 14.5
Nuclei of the trapezoid body
nTPM: 19.4
2166 Male, age 80, both hemispheres 28.5
2368 Female, age 91, both hemispheres 27.5
2159 Male, age 61, both hemispheres 16.5
2735 Female, age 85, both hemispheres 12.8
1983 Male, age 76, both hemispheres 11.7
Nucleus ambiguus
nTPM: 26.6
2071 Male, age 76, both hemispheres 33.0
2096 Female, age 85, both hemispheres 20.2
Nucleus cuneatus
nTPM: 27.6
2380 Male, age 80, both hemispheres 38.0
2808 Female, age 85, both hemispheres 32.8
2100 Male, age 76, both hemispheres 31.0
2805 Female, age 91, both hemispheres 25.3
2564 Male, age 74, both hemispheres 22.5
2562 Male, age 61, both hemispheres 16.2
Nucleus gracilis
nTPM: 27.1
2382 Male, age 80, both hemispheres 37.0
2627 Male, age 74, both hemispheres 24.9
2299 Female, age 85, both hemispheres 19.5
Nucleus raphe magnus
nTPM: 17.6
2459 Female, age 91, both hemispheres 26.6
2455 Male, age 74, both hemispheres 21.9
2328 Male, age 80, both hemispheres 19.9
2051 Male, age 76, both hemispheres 15.9
2160 Male, age 61, both hemispheres 12.1
2172 Female, age 85, both hemispheres 8.9
Nucleus raphe obscurus
nTPM: 47.1
2142 Male, age 76, midline 48.9
2845 Female, age 85, midline 48.9
2800 Male, age 61, midline 43.5
Nucleus raphe pallidus
nTPM: 34.4
2145 Male, age 76, midline 50.8
2183 Male, age 80, midline 27.5
1924 Male, age 61, midline 24.8
Nucleus tractus solitarii
nTPM: 13.1
2656 Male, age 76, both hemispheres 17.6
2307 Male, age 80, both hemispheres 14.0
2191 Female, age 85, both hemispheres 13.0
2144 Female, age 91, right hemisphere 7.9
Paramedian reticular nucleus
nTPM: 27.5
2052 Male, age 76, both hemispheres 38.4
2057 Male, age 80, both hemispheres 28.4
2050 Female, age 85, both hemispheres 25.0
2313 Male, age 61, both hemispheres 18.2
Parvicellular reticular nuclei
nTPM: 29.7
2095 Male, age 76, both hemispheres 36.6
2119 Male, age 80, both hemispheres 29.3
2558 Male, age 74, both hemispheres 23.3
Parvicellular reticular nuclei, medullary
nTPM: 18.9
2189 Female, age 91, both hemispheres 22.9
2091 Female, age 85, both hemispheres 17.5
2181 Male, age 80, left hemisphere 16.3
Peritrigeminal nucleus
nTPM: 22.4
2136 Male, age 76, both hemispheres 25.4
2067 Female, age 85, both hemispheres 20.8
2179 Male, age 61, both hemispheres 20.8
Pontine nuclei
nTPM: 24.2
2454 Male, age 74, left hemisphere 44.2
2319 Female, age 91, both hemispheres 36.3
2109 Female, age 72, unknown 26.8
2115 Male, age 80, left hemisphere 24.0
1863 Male, age 55, unknown 18.3
1968 Male, age 76, left hemisphere 17.1
2727 Male, age 61, right hemisphere 15.7
2787 Female, age 85, both hemispheres 11.2
Pontine raphe nucleus
nTPM: 17.7
2122 Female, age 85, midline 17.7
2853 Male, age 76, midline 17.7
Posteroventral cochlear nucleus
nTPM: 31.9
2135 Female, age 91, both hemispheres 60.1
2341 Male, age 80, both hemispheres 38.1
2070 Male, age 76, both hemispheres 26.8
2752 Female, age 85, both hemispheres 17.9
2371 Male, age 61, both hemispheres 16.6
Prepositus hypoglossal nucleus
nTPM: 24.5
2855 Female, age 85, right hemisphere 33.7
2086 Male, age 80, both hemispheres 15.3
Principal sensory trigeminal nucleus
nTPM: 22.2
2367 Female, age 91, left hemisphere 36.3
2008 Male, age 80, left hemisphere 19.8
2324 Male, age 76, both hemispheres 19.1
2158 Male, age 61, both hemispheres 13.4
Reticular pontine nucleus, caudal
nTPM: 28.6
2559 Male, age 74, both hemispheres 43.7
2457 Female, age 91, both hemispheres 31.5
2092 Male, age 76, both hemispheres 23.6
2332 Male, age 80, right hemisphere 15.8
Reticular pontine nucleus, oral
nTPM: 31.8
2361 Male, age 74, both hemispheres 42.1
2366 Female, age 91, both hemispheres 36.9
1939 Male, age 80, both hemispheres 28.9
2012 Female, age 85, both hemispheres 25.7
2167 Male, age 76, both hemispheres 25.6
Reticulotegmental nucleus
nTPM: 22.9
2322 Female, age 91, both hemispheres 27.1
2452 Male, age 74, both hemispheres 25.5
2333 Male, age 80, both hemispheres 20.4
2325 Male, age 76, both hemispheres 18.6
Spinal trigeminal nucleus, caudal
nTPM: 21.2
2308 Male, age 80, both hemispheres 23.2
2312 Male, age 61, both hemispheres 23.0
2447 Male, age 76, both hemispheres 20.3
2642 Male, age 74, both hemispheres 20.2
2390 Female, age 91, both hemispheres 19.4
Spinal trigeminal nucleus, interpolar
nTPM: 16.0
2033 Male, age 80, both hemispheres 18.6
2386 Female, age 85, both hemispheres 18.1
2389 Female, age 91, both hemispheres 18.1
2066 Male, age 76, right hemisphere 17.0
2625 Male, age 61, both hemispheres 8.2
Spinal trigeminal nucleus, oral
nTPM: 19.5
2164 Male, age 80, both hemispheres 23.4
1978 Male, age 76, both hemispheres 18.2
2737 Female, age 85, both hemispheres 16.7
Spinal vestibular nucleus
nTPM: 25.0
2384 Male, age 74, both hemispheres 35.8
2806 Female, age 85, both hemispheres 29.7
2748 Male, age 76, both hemispheres 26.2
2186 Female, age 91, both hemispheres 24.7
2780 Male, age 80, both hemispheres 20.7
2796 Male, age 61, both hemispheres 13.2
Subcoeruleus area
nTPM: 26.0
2369 Female, age 85, left hemisphere 48.9
2089 Male, age 76, left hemisphere 24.4
1958 Male, age 80, both hemispheres 21.1
2451 Male, age 74, both hemispheres 20.7
2323 Female, age 91, left hemisphere 14.6
Superior olive
nTPM: 26.6
2364 Male, age 74, right hemisphere 31.3
2020 Male, age 76, both hemispheres 28.4
2561 Female, age 91, both hemispheres 26.8
2329 Male, age 80, right hemisphere 26.1
1875 Female, age 85, both hemispheres 20.3
Superior vestibular nucleus
nTPM: 20.6
2015 Male, age 80, both hemispheres 21.0
2061 Male, age 76, both hemispheres 20.5
2383 Male, age 74, both hemispheres 20.4
Ventral medullary reticular nucleus
nTPM: 33.0
2372 Male, age 61, both hemispheres 36.4
2060 Male, age 76, both hemispheres 29.6
Ventral periolivary nuclei
nTPM: 23.7
2023 Male, age 76, both hemispheres 33.6
2794 Female, age 91, left hemisphere 26.5
2165 Male, age 80, both hemispheres 19.1
2130 Female, age 85, both hemispheres 15.6
Ventrolateral medulla, A1-C1 cell groups
nTPM: 24.8
2118 Male, age 80, both hemispheres 32.1
2180 Male, age 61, both hemispheres 27.2
1986 Male, age 76, both hemispheres 24.0
2302 Female, age 91, both hemispheres 20.9
2741 Female, age 85, both hemispheres 19.7
Ventrolateral tegmental area, A5 NE cell group
nTPM: 23.6
2456 Female, age 91, both hemispheres 34.0
2449 Male, age 74, both hemispheres 24.1
1959 Male, age 76, both hemispheres 23.1
2840 Female, age 85, both hemispheres 22.7
2161 Male, age 80, both hemispheres 18.9
2359 Male, age 61, both hemispheres 18.8

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 188.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 188.6
FF:10182-103D2 60 years, female 251.8
FF:10165-103B3 76 years, female 125.5
Medulla oblongata
Scaled Tags Per Million: 160.4
FF:10174-103C3 60 years, female 197.4
FF:10038-101F2 18-64 years, mixed 192.4
FF:10155-103A2 76 years, female 91.3
Pons
Scaled Tags Per Million: 147.3
FF:10033-101E6 18-54 years, mixed 147.3

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 103.1
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 103.1
Samples: 4

Max nTPM: 133.7
Min nTPM: 59.0
Sample A Female 118.1
Sample B Female 59.0
Sample C Male 101.7
Sample D Male 133.7
Pons
nTPM: 59.3
Samples: 4

Max nTPM: 92.8
Min nTPM: 40.9
Sample A Female 50.8
Sample B Female 40.9
Sample C Male 52.5
Sample D Male 92.8

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 74.9
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 74.9
Samples: 4

Max nTPM: 82.1
Min nTPM: 68.9
Sample A Male 71.1
Sample B Male 68.9
Sample C Female 77.3
Sample D Female 82.1

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.9
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 6.9
73718048 Antisense, RP_051121_04_C02, Mouse strain C57BL/6J (56 days, male) 7.4
69549632 Antisense, RP_050303_02_G08, Mouse strain C57BL/6J (56 days, male) 6.3
Pons
Expression energy: 6.3
73718048 Antisense, RP_051121_04_C02, Mouse strain C57BL/6J (56 days, male) 7.1
69549632 Antisense, RP_050303_02_G08, Mouse strain C57BL/6J (56 days, male) 5.5

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